GENE：TFR2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | TFR2 |
| FullNmae | transferrin receptor 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:11762 |
| EnsembleID | ENSG00000106327 |
| Uniprot | Q9UP52 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| TFR2 | mpt | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TFR2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| TFR2 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| TFR2 | GO:0004998,GO:0004998,GO:0005515,GO:0005886,GO:0005886,GO:0005886,GO:0006826,GO:0006879,GO:0006879,GO:0006898,GO:0006953,GO:0009897,GO:0009897,GO:0010039,GO:0031410,GO:0033572,GO:0039706,GO:0045807,GO:0045944,GO:0060586,GO:0071281,GO:0090277,GO:0098794,GO:0099072,GO:0140298,GO:0140298,GO:1903319,GO:1990712 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| TFR2 | hsa:7036 | path:hsa04350 | TGF-beta signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GATA1 | TFR2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | TFR2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | TFR2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | TFR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | TFR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | TFR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | TFR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | TFR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MAD2L2 | TFR2 | 25348397 | N/A | physical interaction | ComPPI |
| SOCS3 | TFR2 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| SEC22A | TFR2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| OLFM4 | TFR2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CD81 | TFR2 | 25348397 25635054 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| PFKL | TFR2 | 25348397 | N/A | physical interaction | ComPPI |
| TFR2 | HFE | 10638746 14525934 25348397 9465039 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| TFR2 | TF | 11027676 14525934 25348397 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| TFR2 | ATP4A | 25348397 | N/A | physical interaction | ComPPI |
| TFR2 | FBXO6 | 25348397 | N/A | physical interaction | ComPPI |
| TFR2 | LRRFIP1 | 25348397 | N/A | physical interaction | ComPPI |
| TFR2 | EXT1 | 25348397 | N/A | physical interaction | ComPPI |
| TFR2 | 25348397 | N/A | physical interaction | ComPPI | |
| HFE | TFR2 | 10638746 16893896 19254567 27898060 9465039 | N/A | N/A | OmniPath |
| TFR2 | HFE | 10638746 16893896 19254567 27898060 9465039 | N/A | N/A | OmniPath |