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GENE：SLC1A5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SLC1A5
FullNmae solute carrier family 1 member 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10943
EnsembleID ENSG00000105281
Uniprot Q15758

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SLC1A5 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SLC1A5 ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SLC1A5 GO:0001618,GO:0005515,GO:0005886,GO:0005886,GO:0005886,GO:0006865,GO:0006868,GO:0006868,GO:0009925,GO:0010585,GO:0015171,GO:0015175,GO:0015183,GO:0015183,GO:0015186,GO:0015186,GO:0015194,GO:0015293,GO:0015297,GO:0015804,GO:0015825,GO:0016020,GO:0016020,GO:0022834,GO:0030218,GO:0038023,GO:0042470,GO:0046718,GO:0046872,GO:0070062,GO:0070207,GO:0140009,GO:0140009,GO:0150104,GO:0150104,GO:1903803

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SLC1A5 hsa:6510 path:hsa04974 Protein digestion and absorption - Homo sapiens (human)
SLC1A5 hsa:6510 path:hsa05230 Central carbon metabolism in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SLC1A5 CEBPD 21072181 23180781 physical association anti tag coimmunoprecipitation InnateDB
ADRB2 SLC1A5 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR SLC1A5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 SLC1A5 18414489 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation array,chromatin immunoprecipitation assay TFlink
ETS1 SLC1A5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 SLC1A5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SLC1A5 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 SLC1A5 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 SLC1A5 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C SLC1A5 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SLC1A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SLC1A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SLC1A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SLC1A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SLC1A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SLC1A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SLC1A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SLC1A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SLC1A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR SLC1A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SLC1A5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 SLC1A5 21512034 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000338542 SLC1A5 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00001F0C23 SLC1A5 20371350 23824327 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00000EED18 SLC1A5 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00002971AB SLC1A5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D SLC1A5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC SLC1A5 23622248 23824327 25416803 mrna cleavage,inhibition clip,clash TarBase
URS000041CB9C SLC1A5 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075AB14 SLC1A5 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000AB32B SLC1A5 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000239117 SLC1A5 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0874 SLC1A5 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 SLC1A5 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000076995 SLC1A5 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 SLC1A5 22291592 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 SLC1A5 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00000C48FA SLC1A5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 SLC1A5 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000022B729 SLC1A5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000272039 SLC1A5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001E3523 SLC1A5 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004214BB SLC1A5 23824327 24906430 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 SLC1A5 19536157 23824327 24906430 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS000008B558 SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E SLC1A5 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005CE28 SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEF5F SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EC1BE SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 SLC1A5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 SLC1A5 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002FB065 SLC1A5 23313552 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000016FD1A SLC1A5 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000024DFCE SLC1A5 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005D12AC SLC1A5 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 SLC1A5 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000007A060 SLC1A5 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00006DE17B SLC1A5 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000031B6ED SLC1A5 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00003E2232 SLC1A5 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000AD002 SLC1A5 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LGALS3 SLC1A5 25348397 N/A physical interaction ComPPI
ISG15 SLC1A5 24234451 25348397 26259872 association pull down ComPPI,IntAct
MCM2 SLC1A5 25348397 N/A physical interaction ComPPI
RNF5 SLC1A5 24234451 25348397 25759021 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
JUN SLC1A5 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
PAXIP1 SLC1A5 25348397 N/A physical interaction ComPPI
CUL3 SLC1A5 25348397 N/A physical interaction ComPPI
NTRK1 SLC1A5 25348397 N/A physical interaction ComPPI
CDH1 SLC1A5 25348397 N/A physical interaction ComPPI
TNFRSF1A SLC1A5 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
MAPK6 SLC1A5 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
VDAC1 SLC1A5 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
CD47 SLC1A5 25348397 N/A physical interaction ComPPI
ECT2 SLC1A5 25348397 N/A physical interaction ComPPI
ADRB2 SLC1A5 25348397 N/A physical interaction ComPPI
EGFR SLC1A5 25348397 N/A physical interaction ComPPI
ITCH SLC1A5 25348397 N/A physical interaction ComPPI
TNFRSF1B SLC1A5 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
CUL7 SLC1A5 25348397 N/A physical interaction ComPPI
CAND1 SLC1A5 25348397 N/A physical interaction ComPPI
HACD2 SLC1A5 25348397 N/A physical interaction ComPPI
NFKB1 SLC1A5 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
TRIM25 SLC1A5 25348397 N/A physical interaction ComPPI
TGOLN2 SLC1A5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
XRCC3 SLC1A5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NEK6 SLC1A5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TMEM132A SLC1A5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TES SLC1A5 25348397 N/A physical interaction ComPPI
NCDN SLC1A5 25348397 N/A physical interaction ComPPI
CYB5R3 SLC1A5 25348397 N/A physical interaction ComPPI
MPDU1 SLC1A5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FUS SLC1A5 25348397 N/A physical interaction ComPPI
SDHAF2 SLC1A5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TBC1D17 SLC1A5 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TUBA1C SLC1A5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YIPF5 SLC1A5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ALB SLC1A5 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ABCB8 SLC1A5 25348397 N/A physical interaction ComPPI
TMEM216 SLC1A5 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MTCH2 SLC1A5 25348397 N/A physical interaction ComPPI
MAP3K1 SLC1A5 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
LAMP1 SLC1A5 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ECPAS SLC1A5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GSTK1 SLC1A5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
LGALS9 SLC1A5 25348397 N/A physical interaction ComPPI
HLA-B SLC1A5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SLC1A5 USP19 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC1A5 USP50 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC1A5 MRPS35 25348397 N/A physical interaction ComPPI
SLC1A5 MCU 25348397 N/A physical interaction ComPPI
SLC1A5 LGR4 25348397 N/A physical interaction ComPPI
SLC1A5 CCDC8 25348397 N/A physical interaction ComPPI
SLC1A5 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SLC1A5 ACSL4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC1A5 TMEM63B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC1A5 MASTL 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC1A5 MBOAT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC1A5 PTPN3 25348397 N/A physical interaction ComPPI
SLC1A5 SLC25A24 25348397 N/A physical interaction ComPPI
SLC1A5 HSD17B7 25348397 N/A physical interaction ComPPI
SLC1A5 GPR89A 25348397 N/A physical interaction ComPPI
SLC1A5 GPR89B 25348397 N/A physical interaction ComPPI
SLC1A5 ATP9A 25348397 N/A physical interaction ComPPI
SLC1A5 ALG5 25348397 N/A physical interaction ComPPI
SLC1A5 SLC25A46 25348397 N/A physical interaction ComPPI
SLC1A5 ZDHHC18 25348397 N/A physical interaction ComPPI
SLC1A5 SERINC1 25348397 N/A physical interaction ComPPI
SLC1A5 TM2D3 25348397 N/A physical interaction ComPPI
SLC1A5 SPPL3 25348397 N/A physical interaction ComPPI
SLC1A5 COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SLC1A5 APOL3 25348397 N/A two hybrid ComPPI
SLC1A5 SFXN1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ERVW-1 SLC1A5 12050356 14525934 16820059 N/A experimental interaction detection HPRD

Visualization










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