GENE：ALOX15B
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ALOX15B |
| FullNmae | arachidonate 15-lipoxygenase type B |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:434 |
| EnsembleID | ENSG00000179593 |
| Uniprot | O15296 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ALOX15B | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ALOX15B | GO:0005506,GO:0005509,GO:0005515,GO:0005634,GO:0005829,GO:0005829,GO:0005856,GO:0005886,GO:0005912,GO:0005925,GO:0006629,GO:0006629,GO:0006644,GO:0006915,GO:0008285,GO:0008285,GO:0008289,GO:0010744,GO:0016020,GO:0016165,GO:0019369,GO:0019369,GO:0019372,GO:0030336,GO:0030850,GO:0030856,GO:0032722,GO:0034440,GO:0035360,GO:0036403,GO:0043651,GO:0045618,GO:0045786,GO:0045926,GO:0050473,GO:0050473,GO:0051122,GO:0051122,GO:0070062,GO:0071926,GO:1901696,GO:1990136,GO:2001303 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ALOX15B | hsa:247 | path:hsa00590 | Arachidonic acid metabolism - Homo sapiens (human) |
| ALOX15B | hsa:247 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
| ALOX15B | hsa:247 | path:hsa04726 | Serotonergic synapse - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | ALOX15B | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| YBX1 | ALOX15B | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ALOX15B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ALOX15B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ALOX15B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ALOX15B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ALOX15B | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SP1 | ALOX15B | 15247906 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| DAND5 | ALOX15B | 15247906 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TRIM21 | ALOX15B | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| RARA | ALOX15B | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| RPH3A | ALOX15B | 25348397 | N/A | physical interaction | ComPPI |
| PPARG | ALOX15B | 25348397 | N/A | physical interaction | ComPPI |
| TRAIP | ALOX15B | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| NPPA | ALOX15B | 25348397 | N/A | physical interaction | ComPPI |
| RXRA | ALOX15B | 25348397 | N/A | physical interaction | ComPPI |
| KIF3A | ALOX15B | 25348397 | N/A | physical interaction | ComPPI |
| TAF5L | ALOX15B | 25348397 | N/A | physical interaction | ComPPI |
| ERAL1 | ALOX15B | 25348397 | N/A | physical interaction | ComPPI |
| KBTBD2 | ALOX15B | 25348397 | N/A | physical interaction | ComPPI |