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GENE：PHKG2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PHKG2
FullNmae phosphorylase kinase catalytic subunit gamma 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8931
EnsembleID ENSG00000156873
Uniprot P15735

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PHKG2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PHKG2 ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PHKG2 GO:0004674,GO:0004689,GO:0005515,GO:0005516,GO:0005524,GO:0005829,GO:0005829,GO:0005964,GO:0005977,GO:0005978,GO:0005980,GO:0006091,GO:0006468,GO:0019899,GO:0045819,GO:0050321

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PHKG2 hsa:5261 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
PHKG2 hsa:5261 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
PHKG2 hsa:5261 path:hsa04922 Glucagon signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PHKG2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PHKG2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F4 PHKG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PHKG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PHKG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 PHKG2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000007340 PHKG2 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF PHKG2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD PHKG2 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000042619A PHKG2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E PHKG2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 PHKG2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 PHKG2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 PHKG2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001938D9 PHKG2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001A6D0C PHKG2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 PHKG2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA PHKG2 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DRG1 PHKG2 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDKN1A PHKG2 25348397 N/A physical interaction ComPPI
MAGEA2 PHKG2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VCP PHKG2 25348397 N/A physical interaction ComPPI
RAC1 PHKG2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PPP1R3C PHKG2 24234451 25348397 28330616 association pull down ComPPI,IntAct
SETDB1 PHKG2 25348397 N/A physical interaction ComPPI
PRKDC PHKG2 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PRKAA1 PHKG2 25348397 N/A physical interaction ComPPI
PHKG1 PHKG2 14525934 25348397 9362479 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PHKG2 UBE3A 25348397 N/A physical interaction ComPPI
PHKG2 NDUFA4 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PHKG2 SCO2 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PHKG2 VDAC2 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PHKG2 FASN 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PHKG2 ACACA 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PHKG2 ZC3H15 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PHKG2 GCN1 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PHKG2 TNPO1 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PHKG2 ATAD3A 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PHKG2 STUB1 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PHKG2 HAUS2 25348397 N/A physical interaction ComPPI
PHKG2 TP53 25348397 N/A physical interaction ComPPI
PHKG2 DOK4 25348397 N/A physical interaction ComPPI
PHKG2 MED23 25348397 N/A physical interaction ComPPI
PHKG2 GAK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PHKG2 LAMC1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PHKG2 PHKB 25348397 N/A physical interaction ComPPI
PHKG2 GTF3C5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PHKG2 CLASP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PHKG2 AP5Z1 25348397 N/A physical interaction ComPPI
PHKG2 FOXK1 25348397 N/A physical interaction ComPPI
PHKG2 EYA2 25348397 N/A physical interaction ComPPI
PHKG2 PRKAB2 25348397 N/A physical interaction ComPPI
PHKG2 PRKAB1 25348397 N/A physical interaction ComPPI
PHKG2 PRKAG1 25348397 N/A physical interaction ComPPI
PHKG2 PRKAG2 25348397 N/A physical interaction ComPPI
PHKG2 DAPK1 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
H3C1 PHKG2 24234451 25348397 26496610 association anti tag coimmunoprecipitation ComPPI,IntAct

Visualization










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