Gene Information gene info

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GENE：ATG3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATG3
FullNmae autophagy related 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20962
EnsembleID ENSG00000144848
Uniprot Q9NT62

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATG3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATG3 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATG3 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ATG3 GO:0000045,GO:0000045,GO:0000045,GO:0000407,GO:0000422,GO:0005515,GO:0005737,GO:0005829,GO:0005829,GO:0005829,GO:0006612,GO:0016567,GO:0019776,GO:0019776,GO:0019777,GO:0019787,GO:0019899,GO:0034274,GO:0043653,GO:0044804,GO:0050765,GO:0061650,GO:1902017

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATG3 hsa:64422 path:hsa04136 Autophagy - other - Homo sapiens (human)
ATG3 hsa:64422 path:hsa04140 Autophagy - animal - Homo sapiens (human)
ATG3 hsa:64422 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CFLAR ATG3 12215447 15760909 17462996 19838173 23301705 23377657 23725295 24070470 26192618 26972597 association N/A ACSN
ATG7 ATG3 26192618 interaction type N/A ACSN
ATG12 ATG3 12207896 22093031 22166994 23030059 23180781 23301705 23725295 24070470 24257061 26192618 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
ATG5 ATG3 22093031 22166994 23030059 23301705 23725295 24070470 24257061 26192618 interaction type N/A ACSN
ATG3 FNBP1L 19342671 23180781 physical association anti tag coimmunoprecipitation InnateDB
ATG3 CFLAR 19838173 23180781 physical association anti tag coimmunoprecipitation InnateDB
ATG3 MAP1LC3A 19838173 23180781 physical association pull down InnateDB
ATG3 ATG12 12207896 23180781 physical association anti tag coimmunoprecipitation InnateDB
ATG3 ATG5 12207896 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR ATG3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ATG3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ATG3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 ATG3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ATG3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 ATG3 N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 ATG3 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS000016D2D4 ATG3 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
ATG3 ATG5 25361965 interaction type N/A PTMCode2
ATG5 ATG3 25361965 interaction type N/A PTMCode2
ATG3 ATG7 25361965 interaction type N/A PTMCode2
ATG7 ATG3 25361965 interaction type N/A PTMCode2
ATG3 BECN1 25361965 interaction type N/A PTMCode2
BECN1 ATG3 25361965 interaction type N/A PTMCode2
ATG3 ATG16L1 25361965 interaction type N/A PTMCode2
ATG16L1 ATG3 25361965 interaction type N/A PTMCode2
ATG3 ATG4B 25361965 interaction type N/A PTMCode2
ATG4B ATG3 25361965 interaction type N/A PTMCode2
GABARAPL1 ATG3 25361965 interaction type N/A PTMCode2
ATG3 GABARAPL1 25361965 interaction type N/A PTMCode2
GABARAPL2 ATG3 25361965 interaction type N/A PTMCode2
ATG3 GABARAPL2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
BAG3 ATG3 25348397 N/A physical interaction ComPPI
GABARAPL2 ATG3 14525934 16303767 17353931 20562859 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,comigration in non denaturing gel electrophoresis,in vitro ComPPI,HPRD,IntAct
MAP1LC3B ATG3 14525934 16303767 18083104 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,comigration in non denaturing gel electrophoresis,in vitro ComPPI,HPRD,IntAct
HRAS ATG3 25348397 N/A physical interaction ComPPI
GTF2F2 ATG3 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
CREBBP ATG3 25348397 N/A physical interaction ComPPI
CLU ATG3 25348397 N/A physical interaction ComPPI
GNAQ ATG3 25348397 N/A physical interaction ComPPI
DLD ATG3 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MAP1S ATG3 25348397 N/A physical interaction ComPPI
XPO1 ATG3 25348397 N/A physical interaction ComPPI
HUWE1 ATG3 25348397 N/A physical interaction ComPPI
GABARAP ATG3 11825910 14525934 16303767 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,comigration in non denaturing gel electrophoresis,in vitro,in vivo ComPPI,HPRD,IntAct
MAP1LC3A ATG3 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPA9 ATG3 25348397 N/A physical interaction ComPPI
FGB ATG3 25348397 N/A physical interaction ComPPI
ASS1 ATG3 25348397 N/A physical interaction ComPPI
CFLAR ATG3 25348397 N/A physical interaction ComPPI
BECN1 ATG3 25348397 N/A physical interaction ComPPI
DFFA ATG3 25348397 N/A physical interaction ComPPI
RPL23 ATG3 25348397 N/A physical interaction ComPPI
FNBP1L ATG3 19342671 25348397 27898060 N/A physical interaction ComPPI,OmniPath
ATG3 ATG12 17353931 20562859 23202584 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,isothermal titration calorimetry,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach ComPPI,IntAct
ATG3 ATG7 11825910 14525934 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
ATG3 AMBRA1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATG3 ATG10 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATG3 ATG16L1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATG3 TECPR1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATG3 ATG5 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATG3 KRT85 25348397 N/A physical interaction ComPPI
ATG3 MAP1B 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATG3 ATG4B 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATG3 OBSL1 25348397 N/A physical interaction ComPPI
ATG3 GABARAPL1 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
ATG3 MAP1LC3C 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATG3 NANS 25348397 N/A physical interaction ComPPI
ATG3 NHLRC2 25348397 N/A physical interaction ComPPI
ATG3 TNFAIP8 25348397 N/A physical interaction ComPPI
ATG3 MAP1LC3B2 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ATG3 ZNF414 25348397 N/A physical interaction ComPPI
ATG3 ACTBL2 25348397 N/A physical interaction ComPPI
ATG3 EFR3A 25348397 N/A physical interaction ComPPI
ATG3 SLX4IP 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ATG3 SLX1A 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ATG3 MOB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATG3 ATG3 20562859 24234451 physical association anti tag coimmunoprecipitation IntAct
SPTAN1 ATG3 24234451 30021884 physical association cross-linking study IntAct
FLOT2 ATG3 19303850 22539722 27898060 N/A N/A OmniPath
ATG7 ATG3 11139573 11825910 12965207 17227760 17986448 20562859 22055190 22055191 22056771 22170151 22325599 23142976 24186333 24191030 27898060 stimulant N/A OmniPath
TP63 ATG3 22356768 27898060 N/A N/A OmniPath
MAP1LC3B ATG3 11100732 11265251 11825910 15355958 16303767 17145710 17227760 20562859 22170151 24023838 27898060 stimulant N/A OmniPath
ATG3 MAP1LC3B 11100732 11265251 11825910 15355958 16303767 17145710 17227760 20562859 24023838 27898060 stimulant N/A OmniPath
ATG3 ATG12 11825910 12207896 17353931 17986448 20562859 20723759 23202584 24186333 27898060 N/A N/A OmniPath
MAP1LC3A ATG3 16303767 19838173 20061800 20562859 22170151 25503391 27898060 stimulant N/A OmniPath
CFLAR ATG3 19838173 27898060 inhibition N/A OmniPath
ATG3 ATG5 12207896 17986448 20562859 24186333 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B1000 ATG3 27087310 direct interaction,inhibition N/A NPInter

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