Gene Information gene info

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GENE：WIPI1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol WIPI1
FullNmae WD repeat domain, phosphoinositide interacting 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25471
EnsembleID ENSG00000070540
Uniprot Q5MNZ9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
WIPI1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
WIPI1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
WIPI1 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
WIPI1 GO:0000045,GO:0000139,GO:0000407,GO:0000421,GO:0000422,GO:0005102,GO:0005515,GO:0005737,GO:0005802,GO:0005829,GO:0005829,GO:0005856,GO:0006497,GO:0006914,GO:0009267,GO:0010008,GO:0019898,GO:0030136,GO:0030331,GO:0030674,GO:0032266,GO:0032266,GO:0034045,GO:0034045,GO:0034497,GO:0044804,GO:0048203,GO:0050681,GO:0080025,GO:0080025,GO:2000786

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
WIPI1 hsa:55062 path:hsa04136 Autophagy - other - Homo sapiens (human)
WIPI1 hsa:55062 path:hsa04140 Autophagy - animal - Homo sapiens (human)
WIPI1 hsa:55062 path:hsa05010 Alzheimer disease - Homo sapiens (human)
WIPI1 hsa:55062 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
WIPI1 hsa:55062 path:hsa05016 Huntington disease - Homo sapiens (human)
WIPI1 hsa:55062 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
WIPI1 hsa:55062 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
WIPI1 hsa:55062 path:hsa05131 Shigellosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 WIPI1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 WIPI1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 WIPI1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 WIPI1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 WIPI1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 WIPI1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 WIPI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA WIPI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF WIPI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 WIPI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 WIPI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS WIPI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A WIPI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF WIPI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 WIPI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 WIPI1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
WIPI1 TPP1 25361965 interaction type N/A PTMCode2
TPP1 WIPI1 25361965 interaction type N/A PTMCode2
WIPI1 LMNA 25361965 interaction type N/A PTMCode2
LMNA WIPI1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
RACK1 WIPI1 25348397 N/A physical interaction ComPPI
AR WIPI1 14525934 15602573 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PPA1 WIPI1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
S100A7 WIPI1 25348397 N/A physical interaction ComPPI
PKP1 WIPI1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BECN1 WIPI1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
ESR1 WIPI1 14525934 15602573 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ESR2 WIPI1 14525934 15602573 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
UHRF1 WIPI1 25348397 N/A physical interaction ComPPI
ATG12 WIPI1 23088497 24234451 25348397 27898060 colocalization confocal microscopy ComPPI,IntAct,OmniPath
CEP76 WIPI1 25348397 N/A physical interaction ComPPI
WIPI1 KCTD15 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
WIPI1 ATG2A 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WIPI1 DNASE2B 25348397 N/A physical interaction ComPPI
LGALS7 WIPI1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WIPI1 WIPI1 20562859 24234451 physical association anti tag coimmunoprecipitation IntAct
ESR1 WIPI1 15602573 27898060 N/A N/A OmniPath
AR WIPI1 15602573 27898060 N/A N/A OmniPath
ESR2 WIPI1 15602573 27898060 N/A N/A OmniPath

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