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GENE：PEBP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PEBP1
FullNmae phosphatidylethanolamine binding protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8630
EnsembleID ENSG00000089220
Uniprot P30086

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PEBP1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PEBP1 ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PEBP1 GO:0003723,GO:0004867,GO:0005515,GO:0005524,GO:0005634,GO:0005829,GO:0008429,GO:0019899,GO:0019901,GO:0043409,GO:0070062

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PEBP1 MAP3K7 11585904 23180781 23331499 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink
RAF1 PEBP1 11585904 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAP3K14 PEBP1 11585904 23180781 physical association anti tag coimmunoprecipitation InnateDB
IKBKB PEBP1 11585904 23180781 physical association anti tag coimmunoprecipitation InnateDB
PEBP1 ERLIN1 11585904 23180781 physical association anti tag coimmunoprecipitation InnateDB
PEBP1 HNF1A 18160415 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL7R PEBP1 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
PEBP1 BRAF 10490027 23331499 stimulation N/A SignaLink,SignaLink
PEBP1 RAF1 10490027 10757792 17097642 23331499 stimulation N/A SignaLink
PEBP1 MAP2K1 10490027 10757792 23331499 stimulation N/A SignaLink
PEBP1 MAP4K4 11585904 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
SMARCA4 PEBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PEBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PEBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PEBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PEBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PEBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
AR PEBP1 23095933 trascriptional regulation,stimulation inferred by curator TFlink
EZH2 PEBP1 22505648 trascriptional regulation,stimulation inferred by curator TFlink
SNAI1 PEBP1 18477483 19538137 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PEBP1 9334192 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000184017 PEBP1 22809510 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000184017 PEBP1 22809510 25017365 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000ED600 PEBP1 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS0000338542 PEBP1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000153377 PEBP1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000018C928 PEBP1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 PEBP1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA PEBP1 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000243FF1 PEBP1 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D PEBP1 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 PEBP1 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A PEBP1 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA PEBP1 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000008C563 PEBP1 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC0F4 PEBP1 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D50C PEBP1 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000302909 PEBP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 PEBP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004900F1 PEBP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF PEBP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 PEBP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 PEBP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F PEBP1 25128483 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
PRKCD PEBP1 22135298 phosphorylation N/A PhosphoSite
TBK1 PEBP1 22135298 phosphorylation N/A PhosphoSite
PRKCA PEBP1 22135298 phosphorylation N/A PhosphoSite
RAF1 PEBP1 25361965 interaction type N/A PTMCode2
PEBP1 RAF1 25361965 interaction type N/A PTMCode2
MAPK1 PEBP1 25361965 interaction type N/A PTMCode2
PEBP1 MAPK1 25361965 interaction type N/A PTMCode2
PEBP1 PRKCG 25361965 interaction type N/A PTMCode2
PRKCG PEBP1 25361965 interaction type N/A PTMCode2
PEBP1 MAP2K1 25361965 interaction type N/A PTMCode2
MAP2K1 PEBP1 25361965 interaction type N/A PTMCode2
PEBP1 PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ PEBP1 25361965 interaction type N/A PTMCode2
PEBP1 PEBP1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LGALS3 PEBP1 25348397 N/A physical interaction ComPPI
PACSIN3 PEBP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 PEBP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
BAG3 PEBP1 25348397 N/A physical interaction ComPPI
CFL1 PEBP1 25348397 N/A physical interaction ComPPI
TRAF6 PEBP1 20043910 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GABARAPL2 PEBP1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
KEAP1 PEBP1 25348397 N/A physical interaction ComPPI
PICK1 PEBP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK1 PEBP1 10490027 10757792 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PIK3R1 PEBP1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PRKCA PEBP1 12551925 14525934 14654844 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PRKCD PEBP1 12551925 14525934 14654844 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
STIP1 PEBP1 25348397 N/A physical interaction ComPPI
PRDX1 PEBP1 25348397 N/A physical interaction ComPPI
IKBKB PEBP1 11585904 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MAP2K1 PEBP1 10757792 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PEBP1 PRKCB 12551925 14525934 14654844 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PEBP1 PRKCG 12551925 14525934 14654844 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PEBP1 PRKCZ 12551925 14525934 14654844 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PEBP1 MAP3K7 11585904 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PEBP1 PPARD 14525934 15001550 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PEBP1 GRK2 14525934 14654844 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PEBP1 CACHD1 12421765 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
PEBP1 CHUK 11585904 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PEBP1 NR2C2 11585904 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PEBP1 MED10 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PEBP1 RAF1 14525934 17097642 21831839 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,peptide array,pull down,surface plasmon resonance,physical interaction,in vitro ComPPI,HPRD,IntAct
PEBP1 STC2 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PEBP1 AKT1 25348397 N/A physical interaction ComPPI
PEBP1 IGBP1 25348397 N/A physical interaction ComPPI
PEBP1 PTGR1 25348397 N/A physical interaction ComPPI
PEBP1 HNF1A 25348397 N/A physical interaction ComPPI
PEBP1 IQCB1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PEBP1 NKX3-1 25348397 N/A physical interaction ComPPI
PEBP1 GSDMB 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PEBP1 MOV10 25348397 N/A physical interaction ComPPI
PEBP1 NXF1 25348397 N/A physical interaction ComPPI
PEBP1 ABCE1 25348397 N/A physical interaction ComPPI
PEBP1 ASNS 25348397 N/A physical interaction ComPPI
PEBP1 C11ORF54 25348397 N/A physical interaction ComPPI
PEBP1 GNPDA2 25348397 N/A physical interaction ComPPI
PEBP1 HSPE1 25348397 N/A physical interaction ComPPI
PEBP1 LDHAL6A 25348397 N/A physical interaction ComPPI
PEBP1 PABPC3 25348397 N/A physical interaction ComPPI
PEBP1 SOD1 25348397 N/A physical interaction ComPPI
PEBP1 SOD2 25348397 N/A physical interaction ComPPI
PEBP1 SPR 25348397 N/A physical interaction ComPPI
PEBP1 UCHL3 25348397 N/A physical interaction ComPPI
PEBP1 YKT6 25348397 N/A physical interaction ComPPI
PEBP1 PGLS 25348397 N/A physical interaction ComPPI
PEBP1 PPIA 25348397 N/A physical interaction ComPPI
PEBP1 PRDX5 25348397 N/A physical interaction ComPPI
PEBP1 RFK 25348397 N/A physical interaction ComPPI
PEBP1 SLC25A32 25348397 N/A physical interaction ComPPI
PEBP1 SCLT1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PEBP1 ALOX15 21831839 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PEBP1 STYX 25348397 N/A physical interaction ComPPI
PEBP1 PINX1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PEBP1 VHL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PEBP1 TMBIM4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PEBP1 FTSJ1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PEBP1 SMYD2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PEBP1 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PEBP1 CDK2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PEBP1 EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PEBP1 PHOSPHO1 24234451 25348397 28330616 association pull down ComPPI,IntAct
MAP3K14 PEBP1 11585904 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PEBP1 PEBP1 14525934 9782050 N/A experimental interaction detection HPRD
SMARCB1 PEBP1 24234451 30108113 association proximity-dependent biotin identification IntAct
PEBP1 TNFRSF19 24234451 30337686 colocalization,physical association anti bait coimmunoprecipitation,fluorescence microscopy IntAct
PRKCA PEBP1 12551925 14654844 20068231 20166139 27898060 stimulant N/A OmniPath
PRKCB PEBP1 12551925 14654844 20068231 20166139 27898060 N/A N/A OmniPath
MAP3K7 PEBP1 11585904 27898060 N/A N/A OmniPath
PEBP1 MAP3K7 11585904 27898060 stimulant N/A OmniPath
PRKCD PEBP1 12551925 14654844 17170028 19096942 20068231 20166139 27898060 stimulant N/A OmniPath
PEBP1 MAP2K1 10490027 1075779 10757792 27898060 stimulant N/A OmniPath
MAP3K14 PEBP1 11585904 27898060 N/A N/A OmniPath
IL7R PEBP1 20167604 27898060 N/A N/A OmniPath
PEBP1 BRAF 10490027 27898060 stimulant N/A OmniPath
PRKCG PEBP1 12551925 14654844 20068231 20166139 27898060 stimulant N/A OmniPath
PRKCZ PEBP1 12551925 14654844 20068231 20166139 27898060 stimulant N/A OmniPath
RAF1 PEBP1 10490027 10757792 11585904 12551925 14654844 17097642 27898060 N/A N/A OmniPath
PEBP1 RAF1 10490027 10757792 11585904 12551925 14654844 17097642 27898060 inhibition,stimulant N/A OmniPath
IKBKB PEBP1 11585904 27898060 N/A N/A OmniPath
PEBP1 MAP4K4 11585904 27898060 stimulant N/A OmniPath

Visualization










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