GENE:SOCS1
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | SOCS1 |
FullNmae | suppressor of cytokine signaling 1 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:19383 |
EnsembleID | ENSG00000185338 |
Uniprot | O15524 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
SOCS1 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
SOCS1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
SOCS1 | GO:0001817,GO:0001932,GO:0004860,GO:0005159,GO:0005515,GO:0005654,GO:0005737,GO:0005829,GO:0005942,GO:0007259,GO:0016567,GO:0019210,GO:0019221,GO:0019901,GO:0030225,GO:0031410,GO:0035556,GO:0036464,GO:0042532,GO:0042532,GO:0043372,GO:0043377,GO:0045444,GO:0045591,GO:0046426,GO:0046426,GO:0046426,GO:0046627,GO:0046854,GO:0046935,GO:0071230 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
SOCS1 | hsa:8651 | path:hsa04120 | Ubiquitin mediated proteolysis - Homo sapiens (human) |
SOCS1 | hsa:8651 | path:hsa04380 | Osteoclast differentiation - Homo sapiens (human) |
SOCS1 | hsa:8651 | path:hsa04630 | JAK-STAT signaling pathway - Homo sapiens (human) |
SOCS1 | hsa:8651 | path:hsa04910 | Insulin signaling pathway - Homo sapiens (human) |
SOCS1 | hsa:8651 | path:hsa04917 | Prolactin signaling pathway - Homo sapiens (human) |
SOCS1 | hsa:8651 | path:hsa04930 | Type II diabetes mellitus - Homo sapiens (human) |
SOCS1 | hsa:8651 | path:hsa04935 | Growth hormone synthesis, secretion and action - Homo sapiens (human) |
SOCS1 | hsa:8651 | path:hsa05145 | Toxoplasmosis - Homo sapiens (human) |
SOCS1 | hsa:8651 | path:hsa05206 | MicroRNAs in cancer - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
SOCS1 | RELA | 10485906 12193701 12811837 14690596 23180781 26192618 | interaction type,physical association | anti tag coimmunoprecipitation | ACSN,InnateDB |
SOCS1 | STAT6 | 10485906 12193701 12223527 12811837 21469115 23124025 26192618 | interaction type | N/A | ACSN |
IRF1 | SOCS1 | 10485906 10820262 11399519 11875494 12417340 12433365 15644117 16127449 16597464 17260466 17689680 18345002 21097505 22461508 23390297 26192618 6357187 8871614 | interaction type | N/A | ACSN |
IL13 | SOCS1 | 10485906 10820262 12223527 12401408 12433365 14610620 14657224 15099563 18250477 18451175 20184663 21097505 26192618 26755705 9535722 | interaction type | N/A | ACSN |
IL4 | SOCS1 | 10485906 10820262 11160275 11371360 11870632 12401408 12433365 12496409 12818165 18250477 1825141 20184663 20856220 21097505 23124025 26192618 2965306 9834059 | interaction type | N/A | ACSN |
STAT1 | SOCS1 | 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 26192618 6357187 7594497 8683106 8871614 | interaction type | N/A | ACSN |
SOCS1 | RIPK1 | 10485906 12193701 12223527 12811837 21469115 23124025 26192618 | interaction type | N/A | ACSN |
SOCS1 | IFNG | 10485906 12193701 12223527 12811837 21469115 23124025 26192618 | interaction type | N/A | ACSN |
SOCS1 | IFNGR1 | 10485906 12193701 12223527 12811837 15522878 18708154 18988627 21469115 23124025 23331499 26192618 | interaction type,stimulation | N/A | ACSN,SignaLink,SignaLink |
SOCS1 | IFNGR2 | 10485906 12193701 12223527 12811837 21469115 23124025 26192618 | interaction type | N/A | ACSN |
SOCS1 | JAK1 | 10201892 10485906 11133764 12193701 12223527 12811837 18988627 21469115 23124025 23331499 26192618 | interaction type,stimulation | N/A | ACSN,SignaLink,SignaLink |
SOCS1 | JAK2 | 10064597 10485906 11713228 11971965 12193701 12223527 12811837 14522994 18988627 19287004 21071413 21469115 23124025 23180781 23331499 26192618 9202126 9344848 | interaction type,stimulation,physical association | pull down | ACSN,InnateDB,SignaLink,SignaLink |
SOCS1 | TIRAP | 16415872 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
SOCS1 | EGR1 | 15545275 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
SOCS1 | IRF1 | 15545275 19482358 23180781 | physical association | anti tag coimmunoprecipitation,electrophoretic mobility supershift assay | InnateDB |
SOCS1 | IRF2 | 15545275 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
SOCS1 | MAP3K5 | 19287004 23180781 | physical association | anti tag coimmunoprecipitation,pull down | InnateDB |
SOCS1 | RASA1 | 18556463 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
SOCS1 | PDCD1 | 21263070 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
SOCS1 | GLI2 | 23180781 24058673 | physical association | anti tag coimmunoprecipitation | InnateDB |
PTPN6 | SOCS1 | 14551136 23331499 | stimulation | N/A | SignaLink,SignaLink |
AXL | SOCS1 | 12470648 23331499 | stimulation | N/A | SignaLink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
SOCS1 | PIK3R2 | 20005715 | interaction type | N/A | PSP |
SOCS1 | JAK2 | 20005715 | interaction type | N/A | PSP,SignaLink |
SOCS1 | ERBB2 | 20005715 | interaction type | N/A | PSP,SignaLink |
SOCS1 | INSR | 20005715 | interaction type | N/A | PSP |
SOCS1 | FYN | 20005715 | interaction type | N/A | PSP |
SOCS1 | CSF1R | 20005715 | interaction type | N/A | PSP |
SOCS1 | IGF1R | 20005715 | interaction type | N/A | PSP |
SOCS1 | PDGFRB | 20005715 | interaction type | N/A | PSP |
SOCS1 | IL2RB | 20005715 | interaction type | N/A | PSP |
SOCS1 | IFNGR1 | 20005715 | interaction type | N/A | PSP,SignaLink |
SOCS1 | JAK1 | 20005715 | interaction type | N/A | PSP |
SOCS1 | AXL | 20005715 | interaction type | N/A | PSP |
SOCS1 | FLT3 | 20005715 | interaction type | N/A | PSP |
SOCS1 | MPL | 20005715 | interaction type | N/A | PSP |
SOCS1 | TEC | 20005715 | interaction type | N/A | PSP |
SOCS1 | JAK3 | 20005715 | interaction type | N/A | PSP |
SOCS1 | TIRAP | 20005715 | interaction type | N/A | PSP,SignaLink |
SOCS1 | CXCR4 | 20005715 | interaction type | N/A | PSP |
SOCS1 | TEK | 20005715 | interaction type | N/A | PSP |
SOCS1 | ITK | 20005715 | interaction type | N/A | PSP |
SOCS1 | CXCR4 | 12163560 18988627 20005715 | N/A | N/A | SignaLink |
SOCS1 | IGF1R | 18988627 20005715 9727029 | N/A | N/A | SignaLink |
SOCS1 | AXL | 20005715 20005715 | N/A | N/A | SignaLink |
SOCS1 | CSF1R | 10022833 11297560 11297560 11297560 11297560 18988627 20005715 20005715 21071413 | N/A | N/A | SignaLink |
SOCS1 | FLT3 | 10022833 18988627 20005715 20005715 | N/A | N/A | SignaLink |
SOCS1 | FYN | 10022833 10022833 18988627 20005715 20005715 21071413 | N/A | N/A | SignaLink |
SOCS1 | IL2RB | 11133764 11133764 18988627 20005715 20005715 21071413 | N/A | N/A | SignaLink |
SOCS1 | INSR | 15169905 18988627 20005715 20005715 | N/A | N/A | SignaLink |
SOCS1 | ITK | 10022833 10022833 18988627 20005715 20005715 21071413 | N/A | N/A | SignaLink |
SOCS1 | JAK1 | 20005715 20005715 | N/A | N/A | SignaLink |
SOCS1 | JAK3 | 11133764 18988627 20005715 20005715 | N/A | N/A | SignaLink |
SOCS1 | MPL | 10517496 20005715 20005715 21071413 | N/A | N/A | SignaLink |
SOCS1 | PDGFRB | 20005715 20005715 | N/A | N/A | SignaLink |
SOCS1 | PIK3R2 | 20005715 20005715 | N/A | N/A | SignaLink |
SOCS1 | TEC | 18988627 20005715 20005715 21071413 9341160 9341160 9341160 | N/A | N/A | SignaLink |
SOCS1 | TEK | 10022833 18988627 20005715 20005715 | N/A | N/A | SignaLink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ETS1 | SOCS1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
YBX1 | SOCS1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
SMARCA4 | SOCS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | SOCS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | SOCS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | SOCS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | SOCS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | SOCS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | SOCS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | SOCS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | SOCS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TAL1 | SOCS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ZNF263 | SOCS1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
GLI1 | SOCS1 | 24058673 | trascriptional regulation,stimulation | inferred by curator | TFlink |
GLI2 | SOCS1 | 24058673 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HIF1A | SOCS1 | 20003295 | trascriptional regulation,stimulation | inferred by curator | TFlink |
IRF1 | SOCS1 | 20644166 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SP1 | SOCS1 | 20644166 | trascriptional regulation,stimulation | inferred by curator | TFlink |
DAND5 | SOCS1 | 20644166 | trascriptional regulation,stimulation | inferred by curator | TFlink |
STAT3 | SOCS1 | 14630083 20003295 20357037 | trascriptional regulation,stimulation | inferred by curator | TFlink |
STAT6 | SOCS1 | 15199062 18342537 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000237CBD | SOCS1 | 21742974 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
URS00003380CC | SOCS1 | 23348614 | rna interference,inhibition | experimental interaction detection | miRSponge |
URS0000338542 | SOCS1 | 20354188 22387553 22771905 \N | rna interference,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
URS000006FDD4 | SOCS1 | 18728182 \N | rna interference,inhibition | western blot,miRNA interference luciferase reporter assay | miRSponge |
URS00002152A8 | SOCS1 | 22387553 | rna interference,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
URS0000338542 | SOCS1 | 18668040 18927107 19144316 20354188 21355095 22387553 22473208 22771905 23436936 24351865 25416803 25998827 27470349 27811366 27817193 | mrna cleavage,inhibition | array technology,experimental interaction detection,western blot,northern blot,rna immunoprecipitation,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay | miR2Disease,TarBase |
URS000006FDD4 | SOCS1 | 18728182 22291592 22473208 23592263 23621248 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay | TarBase |
URS00002152A8 | SOCS1 | 22291592 22387553 22473208 23592263 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay | TarBase |
URS0000237CBD | SOCS1 | 21742974 23592263 25416803 | mrna cleavage,inhibition | clip,miRNA interference luciferase reporter assay | TarBase |
URS00003380CC | SOCS1 | 23348614 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
URS000005CF5F | SOCS1 | 22291592 22473208 23231923 23592263 25416803 | mrna cleavage,inhibition | western blot,clip,miRNA interference luciferase reporter assay | TarBase |
URS0000170CF4 | SOCS1 | 25019494 25416803 | mrna cleavage,inhibition | western blot,miRNA interference luciferase reporter assay | TarBase |
URS000023133F | SOCS1 | 22291592 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000F6E49 | SOCS1 | 22291592 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001123BD | SOCS1 | 22291592 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002CAE0C | SOCS1 | 22291592 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000C5BAA | SOCS1 | 22291592 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001EE123 | SOCS1 | 22291592 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001597DC | SOCS1 | 22291592 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000065D58 | SOCS1 | 22291592 22473208 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001DE669 | SOCS1 | 22291592 22473208 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000A07C1 | SOCS1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000029979D | SOCS1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000032EF64 | SOCS1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000122ED0 | SOCS1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000000B1C9 | SOCS1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000031E12 | SOCS1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000324096 | SOCS1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001E0AEA | SOCS1 | 25416803 26436920 | mrna cleavage,inhibition | array technology,experimental interaction detection,experimental interaction detection,experimental interaction detection,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
URS000009262D | SOCS1 | 25416803 27811366 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
PIK3R2 | SOCS1 | 10022833 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
PIM2 | SOCS1 | 11854514 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
JOSD1 | SOCS1 | 25348397 | N/A | physical interaction | ComPPI |
TRAF6 | SOCS1 | 25348397 | N/A | physical interaction | ComPPI |
TYK2 | SOCS1 | 25348397 | N/A | physical interaction | ComPPI |
CRK | SOCS1 | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
ERBB2 | SOCS1 | 16273093 24234451 25348397 | N/A | protein array,physical interaction | ComPPI,IntAct |
VAV1 | SOCS1 | 10022833 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
TEC | SOCS1 | 14525934 25348397 9341160 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
SOCS1 | KIT | 10022833 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
SOCS1 | PIK3R1 | 10022833 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
SOCS1 | ITK | 10022833 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
SOCS1 | GRB2 | 10022833 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
SOCS1 | JAK3 | 11133764 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
SOCS1 | VAV2 | 10022833 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
SOCS1 | NCK1 | 10022833 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
SOCS1 | ELOB | 10051596 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
SOCS1 | ELOC | 10051596 14525934 15304214 15601820 16643902 17183367 19385048 21119685 22787435 24234451 25348397 27898060 9869640 | physical association | two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid array,in vitro,in vivo | ComPPI,HPRD,IntAct,OmniPath |
SOCS1 | GHR | 10585430 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
SOCS1 | TRIM8 | 12163497 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
SOCS1 | PDGFRB | 10022833 14525934 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
SOCS1 | AXL | 12470648 14525934 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
SOCS1 | CSF1 | 11297560 14525934 25348397 | N/A | two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid | ComPPI,HPRD |
SOCS1 | IFNGR1 | 14525934 15522878 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
SOCS1 | CXCR4 | 12163560 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
SOCS1 | MPL | 10517496 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
SOCS1 | IRS2 | 12228220 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
SOCS1 | TIRAP | 25348397 | N/A | physical interaction,in vivo | ComPPI |
SOCS1 | COMMD1 | 14525934 17183367 24234451 25348397 | physical association | anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro | ComPPI,HPRD,IntAct |
SOCS1 | RELA | 14525934 14690596 17183367 24234451 25348397 | physical association | experimental interaction detection,pull down,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
SOCS1 | EGFR | 12070153 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
SOCS1 | FLT3 | 10022833 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
SOCS1 | FYN | 10022833 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
SOCS1 | IL2RB | 11133764 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
SOCS1 | IRS1 | 11208867 12228220 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
SOCS1 | INSR | 14525934 15169905 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD |
SOCS1 | JAK1 | 11133764 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
SOCS1 | JAK2 | 10064597 10421843 11971965 14525934 24234451 25348397 9202126 | physical association | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct |
SOCS1 | CSF1R | 10022833 11297560 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
SOCS1 | ELOA | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | SOCS2 | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | ALK | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | MAP3K5 | 16407264 24234451 25348397 | association | pull down,physical interaction | ComPPI,IntAct |
SOCS1 | IRF3 | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | IFNAR1 | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | PTPN11 | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | CLEC7A | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | TUBG1 | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | VHL | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | DAB1 | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | RASA1 | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | PDCD1 | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | FGFR3 | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | LCK | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | TP53 | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | ATM | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | ATR | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | CYTIP | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | ABL1 | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | CSF2RB | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | CRKL | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array,validated two hybrid | ComPPI,IntAct |
SOCS1 | MET | 24234451 24728074 25348397 25728680 27898060 | N/A | fluorescence polarization spectroscopy,physical interaction | ComPPI,IntAct,OmniPath |
SOCS1 | NECTIN1 | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | IL7R | 25348397 | N/A | physical interaction | ComPPI |
SOCS1 | TUBA3C | 19327355 24234451 25348397 27898060 | colocalization | fluorescence microscopy | ComPPI,IntAct,OmniPath |
SOCS1 | CUL2 | 19327355 24234451 25348397 | association | pull down | ComPPI,IntAct |
SOCS1 | SH3GL1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
ETV6 | SOCS1 | 25348397 | N/A | physical interaction | ComPPI |
IGF1R | SOCS1 | 14525934 25348397 9727029 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
SOCS1 | TEK | 10022833 14525934 | N/A | two hybrid | HPRD |
SOCS1 | IFNGR1 | 15522878 1552288 18708154 27898060 | inhibition,stimulant | N/A | OmniPath |
PDCD1 | SOCS1 | 21263070 27898060 | N/A | N/A | OmniPath |
SOCS1 | JAK3 | 11133764 21508344 27898060 | inhibition | N/A | OmniPath |
KAT2A | SOCS1 | 19339690 27898060 | stimulant | N/A | OmniPath |
SOCS1 | MAP3K5 | 16407264 18776134 19287004 27898060 | N/A | N/A | OmniPath |
MAP3K5 | SOCS1 | 16407264 18776134 19287004 27898060 | N/A | N/A | OmniPath |
PTPN6 | SOCS1 | 14551136 27898060 | stimulant | N/A | OmniPath |
STAT1 | SOCS1 | 15240659 27898060 | inhibition,stimulant | N/A | OmniPath |
SOCS1 | JAK1 | 10201892 1113376 11133764 15456882 23663276 23990909 27898060 9202126 | inhibition,stimulant | N/A | OmniPath |
RELA | SOCS1 | 14690596 17183367 21084693 27898060 | N/A | N/A | OmniPath |
TRIM8 | SOCS1 | 12163497 27898060 | inhibition | N/A | OmniPath |
SOCS1 | JAK2 | 10064597 10421843 10455112 11314018 11713228 11971965 14522994 18508766 19287004 27898060 9202126 9344848 | inhibition,stimulant | N/A | OmniPath |
JAK2 | SOCS1 | 10064597 10421843 10455112 11314018 11713228 11971965 14522994 18508766 19287004 27898060 9202126 9344848 | N/A | N/A | OmniPath |
SOCS1 | TIRAP | 16415872 27898060 | N/A | N/A | OmniPath |
TIRAP | SOCS1 | 16415872 27898060 | N/A | N/A | OmniPath |
SOCS1 | IRAK1 | 12433373 27898060 | inhibition | N/A | OmniPath |
SOCS1 | RASA1 | 18556463 27898060 | N/A | N/A | OmniPath |
AXL | SOCS1 | 12470648 27898060 | stimulant | N/A | OmniPath |