Gene Information gene info

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GENE：ANO6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ANO6
FullNmae anoctamin 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25240
EnsembleID ENSG00000177119
Uniprot Q4KMQ2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ANO6 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ANO6 GO:0002543,GO:0005227,GO:0005227,GO:0005227,GO:0005229,GO:0005229,GO:0005244,GO:0005247,GO:0005254,GO:0005515,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0006812,GO:0006821,GO:0007596,GO:0009986,GO:0016020,GO:0017121,GO:0017121,GO:0017128,GO:0030501,GO:0032060,GO:0034220,GO:0034707,GO:0034767,GO:0035579,GO:0035590,GO:0035725,GO:0043065,GO:0045794,GO:0046872,GO:0046931,GO:0046983,GO:0060100,GO:0061589,GO:0061590,GO:0070062,GO:0070588,GO:0070821,GO:0090026,GO:0097045,GO:1902476,GO:1902476,GO:1903766,GO:2000353

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ANO6 hsa:196527 path:hsa04148 Efferocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ANO6 CEBPD 21072181 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR ANO6 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ANO6 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ANO6 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 ANO6 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ANO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ANO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ANO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ANO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ANO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ANO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ANO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ANO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ANO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 ANO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ANO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ANO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR ANO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 ANO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B59A2 ANO6 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 ANO6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CC379 ANO6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 ANO6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004818BD ANO6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002CCA6E ANO6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 ANO6 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LGALS9C ANO6 25348397 N/A physical interaction ComPPI
CDC16 ANO6 25348397 N/A physical interaction ComPPI
CANX ANO6 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
LGALS8 ANO6 25348397 N/A physical interaction ComPPI
ELAVL1 ANO6 25348397 N/A physical interaction ComPPI
SLC51A ANO6 25348397 N/A physical interaction ComPPI
ANAPC5 ANO6 25348397 N/A physical interaction ComPPI
UPK1A ANO6 25348397 N/A physical interaction ComPPI
CDC27 ANO6 25348397 N/A physical interaction ComPPI
PREB ANO6 25348397 N/A physical interaction ComPPI
FAM189A2 ANO6 25348397 N/A physical interaction ComPPI
CDC23 ANO6 25348397 N/A physical interaction ComPPI
TMEM216 ANO6 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CDC26 ANO6 25348397 N/A physical interaction ComPPI
ANAPC1 ANO6 25348397 N/A physical interaction ComPPI
ANAPC4 ANO6 25348397 N/A physical interaction ComPPI
DLK1 ANO6 25348397 N/A physical interaction ComPPI
ZNRF4 ANO6 25348397 N/A physical interaction ComPPI
MIA3 ANO6 25348397 N/A physical interaction ComPPI
TCTN2 ANO6 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ANO6 POPDC2 25348397 N/A physical interaction ComPPI
ANO6 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ANO6 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ANO6 MIA2 25348397 N/A physical interaction ComPPI
ANO6 LMAN2L 25348397 N/A physical interaction ComPPI
ANO6 ADGRG5 25348397 N/A physical interaction ComPPI
ANO6 GPR21 25348397 N/A physical interaction ComPPI
ANO6 LRRC8B 25348397 N/A physical interaction ComPPI
ANO6 LEMD2 25348397 N/A physical interaction ComPPI

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