Gene Information gene info

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GENE：PANX1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PANX1
FullNmae pannexin 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8599
EnsembleID ENSG00000110218
Uniprot Q96RD7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PANX1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PANX1 GO:0002020,GO:0002931,GO:0005102,GO:0005198,GO:0005262,GO:0005515,GO:0005783,GO:0005789,GO:0005886,GO:0005886,GO:0005886,GO:0005921,GO:0006812,GO:0006812,GO:0006816,GO:0007267,GO:0016020,GO:0022829,GO:0022840,GO:0032059,GO:0032730,GO:0032731,GO:0032991,GO:0033198,GO:0044325,GO:0048477,GO:0051015,GO:0060907,GO:0070588,GO:0097110

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PANX1 hsa:24145 path:hsa04148 Efferocytosis - Homo sapiens (human)
PANX1 hsa:24145 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NLRP2 PANX1 23180781 23625868 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR PANX1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 PANX1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 PANX1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PANX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PANX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PANX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PANX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PANX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PANX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PANX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PANX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PANX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PANX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B59A2 PANX1 16822819 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00001F0C23 PANX1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000016D2D4 PANX1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00003A8BB2 PANX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A PANX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 PANX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 PANX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B PANX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F PANX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 PANX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE PANX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 PANX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 PANX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 PANX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 PANX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C PANX1 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD02D PANX1 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PANX1 KCNAB3 25361965 interaction type N/A PTMCode2
KCNAB3 PANX1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
VAMP5 PANX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BAG3 PANX1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BCL2L2 PANX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
APOA2 PANX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NF2 PANX1 25348397 N/A physical interaction ComPPI
CASP3 PANX1 20944749 24234451 25348397 protein cleavage protease assay,protein cleavage ComPPI,IntAct
CASP7 PANX1 20944749 24234451 25348397 protein cleavage protease assay,protein cleavage ComPPI,IntAct
TNF PANX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GRPR PANX1 25348397 N/A physical interaction ComPPI
CDC37 PANX1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GNAS PANX1 25348397 N/A physical interaction ComPPI
FBXO7 PANX1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
C5AR2 PANX1 25348397 N/A physical interaction ComPPI
P2RX7 PANX1 17036048 25348397 27898060 N/A in vivo ComPPI,OmniPath
HTR3A PANX1 25348397 N/A physical interaction ComPPI
WFDC2 PANX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
APOL2 PANX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PANX1 GNAS 25348397 N/A physical interaction ComPPI
PANX1 GNAS 25348397 N/A physical interaction ComPPI
PANX1 C4ORF3 25348397 N/A physical interaction ComPPI
PANX1 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PANX1 SLC38A7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PANX1 FAXDC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PANX1 FDFT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AQP2 PANX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PANX1 BUD31 24234451 28298427 physical association ubiquitin reconstruction IntAct

Visualization










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