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GENE：DNAJB6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DNAJB6
FullNmae DnaJ heat shock protein family (Hsp40) member B6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14888
EnsembleID ENSG00000105993
Uniprot O75190

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DNAJB6 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DNAJB6 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DNAJB6 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DNAJB6 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DNAJB6 GO:0001671,GO:0001671,GO:0003677,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0006457,GO:0016020,GO:0030018,GO:0030036,GO:0030198,GO:0030544,GO:0031072,GO:0032880,GO:0034504,GO:0043154,GO:0044183,GO:0045109,GO:0045892,GO:0048471,GO:0051082,GO:0051082,GO:0051087,GO:0051087,GO:0051087,GO:0060710,GO:0060715,GO:0060717,GO:0061077,GO:0090084,GO:0090084,GO:1900034

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR DNAJB6 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DNAJB6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 DNAJB6 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 DNAJB6 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DNAJB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DNAJB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DNAJB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DNAJB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DNAJB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DNAJB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DNAJB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DNAJB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 DNAJB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DNAJB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 DNAJB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 DNAJB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 DNAJB6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000600E6 DNAJB6 17242205 22012620 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS00000EED18 DNAJB6 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00004F24A9 DNAJB6 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 DNAJB6 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB DNAJB6 22012620 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000012A1DD DNAJB6 22012620 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000171525 DNAJB6 22012620 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000055BBE5 DNAJB6 22012620 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000004203C DNAJB6 22012620 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000105D19 DNAJB6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 DNAJB6 22012620 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B2B DNAJB6 22012620 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 DNAJB6 22012620 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000075A513 DNAJB6 22012620 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 DNAJB6 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA DNAJB6 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003677B2 DNAJB6 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 DNAJB6 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 DNAJB6 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE DNAJB6 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F DNAJB6 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 DNAJB6 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 DNAJB6 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 DNAJB6 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA DNAJB6 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HSPA8 DNAJB6 25361965 interaction type N/A PTMCode2
DNAJB6 HSPA8 25361965 interaction type N/A PTMCode2
DNAJB6 USP8 25361965 interaction type N/A PTMCode2
USP8 DNAJB6 25361965 interaction type N/A PTMCode2
DNAJB6 KRT18 25361965 interaction type N/A PTMCode2
KRT18 DNAJB6 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KRT18 DNAJB6 10954706 14525934 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,cosedimentation,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
HSPA8 DNAJB6 10954706 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
CIAO2B DNAJB6 25348397 N/A physical interaction ComPPI
BAG3 DNAJB6 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
S100A4 DNAJB6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRMS1 DNAJB6 16919237 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction,in vivo ComPPI,IntAct
HSPB8 DNAJB6 25348397 N/A physical interaction ComPPI
ERBB2 DNAJB6 24189400 24234451 25348397 association tandem affinity purification ComPPI,IntAct
SKAP2 DNAJB6 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
HDAC4 DNAJB6 18163532 20159555 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TTN DNAJB6 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
CUL3 DNAJB6 25348397 N/A physical interaction ComPPI
PIK3CA DNAJB6 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBC DNAJB6 25348397 N/A physical interaction ComPPI
UBE2N DNAJB6 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
PGM1 DNAJB6 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
NTRK1 DNAJB6 25348397 N/A physical interaction ComPPI
BAG1 DNAJB6 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
STIP1 DNAJB6 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPA1A DNAJB6 25348397 N/A physical interaction ComPPI
HSPA1B DNAJB6 25348397 N/A physical interaction ComPPI
MYC DNAJB6 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DNAJB2 DNAJB6 25348397 N/A physical interaction ComPPI
SGCG DNAJB6 23414517 24234451 25348397 physical association two hybrid fragment pooling approach,proximity ligation assay ComPPI,IntAct
DUSP16 DNAJB6 24234451 25348397 28330616 association pull down ComPPI,IntAct
CFTR DNAJB6 25348397 N/A physical interaction ComPPI
MAPK6 DNAJB6 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
TP73 DNAJB6 25348397 N/A physical interaction ComPPI
XPO1 DNAJB6 25348397 N/A physical interaction ComPPI
CUL2 DNAJB6 25348397 N/A physical interaction ComPPI
SOX2 DNAJB6 25348397 N/A physical interaction ComPPI
TUBA1A DNAJB6 24234451 25348397 27291054 29568061 association pull down ComPPI,IntAct
MYOM1 DNAJB6 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
ANKRD1 DNAJB6 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
HDAC6 DNAJB6 25348397 N/A physical interaction ComPPI
ASAP1 DNAJB6 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
USP8 DNAJB6 14525934 15342353 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TP63 DNAJB6 25348397 N/A physical interaction ComPPI
SIRT2 DNAJB6 25348397 N/A physical interaction ComPPI
TUBGCP3 DNAJB6 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
BAG4 DNAJB6 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD2 DNAJB6 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HIF1AN DNAJB6 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
HDAC11 DNAJB6 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA1 DNAJB6 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
TRIM25 DNAJB6 25348397 N/A physical interaction ComPPI
DYNLT1 DNAJB6 25348397 N/A physical interaction ComPPI
ESR1 DNAJB6 25348397 N/A physical interaction ComPPI
BRAF DNAJB6 25348397 N/A physical interaction ComPPI
DYSF DNAJB6 23414517 24234451 25348397 physical association two hybrid fragment pooling approach,proximity ligation assay ComPPI,IntAct
STUB1 DNAJB6 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ESRRB DNAJB6 25348397 N/A physical interaction ComPPI
UBE2V1 DNAJB6 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
DNAJB6 TP53 25348397 N/A physical interaction ComPPI
DNAJB6 ALKBH1 25348397 N/A physical interaction ComPPI
DNAJB6 APP 25348397 N/A physical interaction ComPPI
DNAJB6 POLR1D 25348397 N/A physical interaction ComPPI
DNAJB6 POLR1D 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DNAJB6 TARDBP 25348397 N/A physical interaction ComPPI
DNAJB6 BAG2 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DNAJB6 FKBP5 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DNAJB6 MLF2 23414517 24234451 25036637 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,two hybrid fragment pooling approach ComPPI,IntAct
DNAJB6 CIAO2A 25348397 N/A physical interaction ComPPI
DNAJB6 HSPA6 25348397 N/A physical interaction ComPPI
DNAJB6 MAP3K1 25348397 N/A physical interaction ComPPI
DNAJB6 MLF1 23414517 24234451 25036637 25348397 physical association physical interaction,two hybrid fragment pooling approach,luminescence based mammalian interactome mapping ComPPI,IntAct
DNAJB6 NOPCHAP1 25348397 N/A physical interaction ComPPI
DNAJB6 CEP164 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
DNAJB6 MATR3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DNAJB6 ZNF746 25348397 N/A physical interaction ComPPI
DNAJB6 CYLD 25348397 N/A physical interaction ComPPI
DNAJB6 PHLDA3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DNAJB6 TSC22D1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DNAJB6 GH1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DNAJB6 KRT8 10954706 24234451 25348397 physical association cosedimentation,cosedimentation in solution ComPPI,IntAct
DNAJB6 SLX4 19596235 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
DNAJB6 CAND2 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
DNAJB6 MRTO4 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
DNAJB6 MYBPC1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
DNAJB6 SUPT6H 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
DNAJB6 L3MBTL1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
DNAJB6 ZNF211 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
DNAJB6 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
DNAJB6 TCTE1 24234451 25348397 26638075 association proximity-dependent biotin identification ComPPI,IntAct
DNAJB6 IFT27 24234451 25348397 27173435 association anti tag coimmunoprecipitation ComPPI,IntAct
DNAJB6 NBEAL2 24234451 25348397 29187380 association tandem affinity purification ComPPI,IntAct
METTL3 DNAJB6 24234451 29507755 association anti tag coimmunoprecipitation IntAct
GPX8 DNAJB6 24234451 30021884 physical association cross-linking study IntAct

Source Target Pmid Interactiontype Methods Database
URS00008B448E DNAJB6 27087310 direct interaction,inhibition N/A NPInter

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