GENE：BACH1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | BACH1 |
| FullNmae | BTB domain and CNC homolog 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:935 |
| EnsembleID | ENSG00000156273 |
| Uniprot | O14867 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| BACH1 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| BACH1 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| BACH1 | ferroptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
| BACH1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| BACH1 | GO:0000083,GO:0000117,GO:0000122,GO:0000122,GO:0000122,GO:0000785,GO:0000978,GO:0000981,GO:0000981,GO:0001227,GO:0001227,GO:0001228,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0006281,GO:0006355,GO:0006357,GO:0006357,GO:0019222,GO:0020037,GO:0045944,GO:0090575,GO:0090575,GO:0090575 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | BACH1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | BACH1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | BACH1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | BACH1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | BACH1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | BACH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | BACH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | BACH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | BACH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | BACH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | BACH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | BACH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | BACH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | BACH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | BACH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | BACH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| BRCA1 | BACH1 | 14576433 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA1 | BACH1 | 16492768 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000338542 | BACH1 | N/A 17881434 18299402 18367535 19193853 20584899 21541331 | rna interference,inhibition | array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay | miRSponge |
| URS0000338542 | BACH1 | 17881434 18299402 18367535 19193853 20584899 21541331 23313552 25128227 25416803 | mrna cleavage,inhibition | array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay | TarBase |
| URS00004E008F | BACH1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000042E1F | BACH1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00002367FA | BACH1 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004719AB | BACH1 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00006097A6 | BACH1 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000070CD2 | BACH1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000346991 | BACH1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027080C | BACH1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E949 | BACH1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000508C13 | BACH1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000E601 | BACH1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039607D | BACH1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000037E170 | BACH1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000324096 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000031E12 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000A07C1 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000000B1C9 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000122ED0 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029979D | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000237CBD | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001E0AEA | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000052E1A6 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001941B8 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032EF64 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039A25B | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000272039 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C02E4 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008AA34 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000259AE4 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A4ABF | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003A8BB2 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AFAD1 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000080D0A | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000496C56 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000319E1 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000037B2E0 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000118224 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004283FE | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AEA5 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075B13F | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000CF1D2 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000004203C | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000047A67D | BACH1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000610EFA | BACH1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000030F801 | BACH1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003B59DF | BACH1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000001EB3 | BACH1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000028DE3F | BACH1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000083D87 | BACH1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D0874 | BACH1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000239117 | BACH1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FF9C | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | BACH1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002F5FEE | BACH1 | 22927820 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075B538 | BACH1 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | BACH1 | 22927820 23446348 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | BACH1 | 22927820 23446348 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000019F055 | BACH1 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E11D | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003D8730 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000260A3A | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000038718E | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000003BF62 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005E6F45 | BACH1 | 20371350 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FF522 | BACH1 | 20371350 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002F3336 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD002 | BACH1 | 20371350 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000036B845 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002CEB74 | BACH1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C28B2 | BACH1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016E46F | BACH1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C04A2 | BACH1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| BACH1 | MAFK | 25361965 | interaction type | N/A | PTMCode2 |
| MAFK | BACH1 | 25361965 | interaction type | N/A | PTMCode2 |
| BACH1 | BRCA1 | 25361965 | interaction type | N/A | PTMCode2 |
| BRCA1 | BACH1 | 25361965 | interaction type | N/A | PTMCode2 |
| BACH1 | MAFG | 25361965 | interaction type | N/A | PTMCode2 |
| MAFG | BACH1 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| BATF | BACH1 | 20102225 24234451 25348397 | N/A | peptide array | ComPPI,IntAct |
| CREBZF | BACH1 | 25348397 | N/A | physical interaction | ComPPI |
| NLK | BACH1 | 23602568 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| MAF | BACH1 | 20102225 24234451 25348397 | N/A | peptide array | ComPPI,IntAct |
| SMAD3 | BACH1 | 25348397 | N/A | physical interaction | ComPPI |
| MAFB | BACH1 | 20102225 24234451 25348397 | N/A | peptide array,physical interaction | ComPPI,IntAct |
| CREB5 | BACH1 | 25348397 | N/A | physical interaction | ComPPI |
| NFE2L2 | BACH1 | 25348397 | N/A | physical interaction | ComPPI |
| MAFG | BACH1 | 20102225 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,peptide array,physical interaction | ComPPI,IntAct |
| MAFF | BACH1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NCOR1 | BACH1 | 25348397 | N/A | physical interaction | ComPPI |
| BRCA2 | BACH1 | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | BACH1 | 15175654 25348397 26673895 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| TRIP11 | BACH1 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| PPHLN1 | BACH1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PRKN | BACH1 | 25348397 | N/A | physical interaction | ComPPI |
| BARD1 | BACH1 | 25348397 | N/A | physical interaction | ComPPI |
| MAFK | BACH1 | 14525934 24234451 25348397 26496610 8887638 | association | anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD,IntAct |
| BACH1 | PATZ1 | 10669750 14525934 25348397 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD |
| BACH1 | RBCK1 | 14525934 17682061 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| BACH1 | BRCA1 | 25348397 | N/A | physical interaction,genetic | ComPPI |
| BACH1 | TP53 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | HDAC1 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | BRCC3 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | NBN | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | MRE11 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | MLH1 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | TOPBP1 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | PALB2 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | DDIT3 | 20102225 24234451 25348397 | N/A | peptide array,physical interaction | ComPPI,IntAct |
| BACH1 | ANAPC5 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| BACH1 | FBXL17 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | CSNK1A1 | 23455922 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| BACH1 | SHMT2 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | MOV10 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | RFPL2 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | PLRG1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| BACH1 | TAF4B | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| BACH1 | DDX39B | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| BACH1 | PABPN1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| BACH1 | VIRMA | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| BACH1 | TMEM208 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | FAM83D | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | TBC1D10A | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | ATP23 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | KIF2B | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | ZNF131 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | SLX1A | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | ATF7 | 20102225 24234451 25348397 | N/A | peptide array,physical interaction | ComPPI,IntAct |
| BACH1 | FGFRL1 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | MLX | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | FBXO22 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | RELCH | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | ASAP3 | 25348397 | N/A | physical interaction | ComPPI |
| BACH1 | NME8 | 24234451 25348397 27173435 | physical association | physical interaction,tandem affinity purification,inference by socio-affinity scoring | ComPPI,IntAct |
| BACH1 | PTBP3 | 22575643 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| BACH1 | FOS | 20102225 24234451 25348397 | N/A | peptide array | ComPPI,IntAct |
| BACH1 | ATF1 | 20102225 24234451 25348397 | N/A | peptide array | ComPPI,IntAct |
| BACH1 | CREB1 | 20102225 24234451 25348397 | N/A | peptide array | ComPPI,IntAct |
| HMMR | BACH1 | 15809329 19011633 25348397 26496610 27898060 | N/A | anti tag coimmunoprecipitation,physical interaction | ComPPI,OmniPath |
| ATF2 | BACH1 | 20102225 24234451 25348397 | N/A | peptide array,physical interaction | ComPPI,IntAct |
| BATF3 | BACH1 | 25348397 | N/A | physical interaction | ComPPI |
| H3-4 | BACH1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| BACH1 | NQO1 | 15734732 27898060 | inhibition | N/A | OmniPath |
| BACH1 | NFE2L2 | 15734732 19897490 27898060 | inhibition | N/A | OmniPath |