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GENE：UIMC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UIMC1
FullNmae ubiquitin interaction motif containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30298
EnsembleID ENSG00000087206
Uniprot Q96RL1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UIMC1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
UIMC1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UIMC1 GO:0003677,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0006282,GO:0006302,GO:0006302,GO:0006325,GO:0007095,GO:0010212,GO:0016604,GO:0035861,GO:0042393,GO:0042393,GO:0044818,GO:0045739,GO:0045739,GO:0045892,GO:0046872,GO:0061649,GO:0070530,GO:0070530,GO:0070531,GO:0070531,GO:0070531

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UIMC1 hsa:51720 path:hsa03440 Homologous recombination - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 UIMC1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 UIMC1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 UIMC1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 UIMC1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 UIMC1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC UIMC1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 UIMC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UIMC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UIMC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 UIMC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UIMC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 UIMC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UIMC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UIMC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 UIMC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 UIMC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CSNK2A1 UIMC1 22135298 phosphorylation N/A PhosphoSite
CHEK1 UIMC1 22135298 phosphorylation N/A PhosphoSite
CDK1 UIMC1 22135298 phosphorylation N/A PhosphoSite
ATR UIMC1 22135298 phosphorylation N/A PhosphoSite
ATM UIMC1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
UBE2I UIMC1 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
SPATA2 UIMC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DPY30 UIMC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SKIL UIMC1 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
AMOT UIMC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WBP2 UIMC1 25348397 N/A physical interaction ComPPI
TP53BP1 UIMC1 22884692 24234451 25348397 29656893 colocalization,association confocal microscopy,proximity-dependent biotin identification ComPPI,IntAct
H2BC4 UIMC1 25348397 N/A physical interaction ComPPI
INO80B UIMC1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ABRAXAS2 UIMC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUMO1 UIMC1 25348397 N/A physical interaction ComPPI
CPNE1 UIMC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAXIP1 UIMC1 25348397 N/A physical interaction ComPPI
UBB UIMC1 25348397 N/A nuclear magnetic resonance,physical interaction ComPPI
UBC UIMC1 17311814 17525341 19015238 19261749 19305427 19536136 19944020 20698691 22350954 22605335 22689573 23211528 23314748 23562397 23823328 24627472 25348397 25756347 27898060 N/A nuclear magnetic resonance,physical interaction ComPPI,OmniPath
RPS27A UIMC1 25348397 N/A nuclear magnetic resonance,physical interaction ComPPI
UBA52 UIMC1 25348397 N/A nuclear magnetic resonance,physical interaction ComPPI
PARP1 UIMC1 25348397 N/A physical interaction ComPPI
CAPZA1 UIMC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
C1QBP UIMC1 25348397 N/A physical interaction ComPPI
CASK UIMC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAD51 UIMC1 17525340 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
BLM UIMC1 23708797 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
H2BC21 UIMC1 25348397 N/A physical interaction ComPPI
RBBP8 UIMC1 17525340 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS2 UIMC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS6 UIMC1 25348397 N/A physical interaction ComPPI
RAD23A UIMC1 25348397 N/A physical interaction ComPPI
USP13 UIMC1 25348397 N/A physical interaction ComPPI
SUMO2 UIMC1 22689573 23211528 25348397 26719330 27898060 N/A physical interaction ComPPI,OmniPath
NAE1 UIMC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DVL2 UIMC1 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MDM2 UIMC1 25348397 N/A physical interaction ComPPI
HSPA4 UIMC1 25348397 N/A physical interaction ComPPI
RIOX2 UIMC1 25348397 N/A physical interaction ComPPI
MDC1 UIMC1 21622030 21857162 22990118 24234451 25348397 27898060 29656893 association anti bait coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct,OmniPath
TRAIP UIMC1 25348397 N/A physical interaction ComPPI
F7 UIMC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H3C1 UIMC1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
LIN7C UIMC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BARD1 UIMC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM25 UIMC1 25348397 N/A physical interaction ComPPI
H2AX UIMC1 18001824 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
NR6A1 UIMC1 12080054 14525934 17416745 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
ESR1 UIMC1 25348397 N/A physical interaction ComPPI
RFC4 UIMC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRCA1 UIMC1 17525340 24234451 25348397 29656893 colocalization,association,physical association anti bait coimmunoprecipitation,pull down,physical interaction,fluorescence microscopy,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
CCNA2 UIMC1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 CEP57 12954732 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD,OmniPath
UIMC1 ABRAXAS1 14525934 17525340 19615732 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
UIMC1 BABAM2 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 BRCC3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 ALB 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 CAPZB 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 CDK1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 DLST 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 NRDC 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 PFAS 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 UBA3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 BAG5 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 ERP44 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 BABAM1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 SSU72 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 NOP53 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 G3BP1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 G3BP2 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 WDR48 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 PYCR3 25348397 N/A physical interaction ComPPI
UIMC1 THNSL1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UIMC1 TP53 25348397 N/A physical interaction ComPPI
UIMC1 ATP8A2 25348397 N/A physical interaction ComPPI
UIMC1 H2AC20 25348397 N/A physical interaction ComPPI
UIMC1 FANCG 25348397 N/A physical interaction ComPPI
UIMC1 SHMT2 25348397 N/A physical interaction ComPPI
UIMC1 MOV10 25348397 N/A physical interaction ComPPI
UIMC1 NXF1 25348397 N/A physical interaction ComPPI
UIMC1 H2BC11 25348397 N/A physical interaction ComPPI
UIMC1 COMMD8 25348397 N/A physical interaction ComPPI
UIMC1 LDLRAD4 25348397 N/A physical interaction ComPPI
ECPAS UIMC1 25348397 N/A physical interaction ComPPI
ATR UIMC1 18519686 27898060 stimulant N/A OmniPath
CDK1 UIMC1 19615732 23264621 27898060 N/A N/A OmniPath
UBE2I UIMC1 17698038 19549727 27898060 stimulant N/A OmniPath
SUMO1 UIMC1 17698038 27898060 stimulant N/A OmniPath
UIMC1 BRCA1 17525340 17525341 17525342 17621610 19261748 19305427 19615732 19766185 21622030 24085845 25184681 25252691 27898060 stimulant N/A OmniPath

Visualization










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