GENE:POR
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | POR |
| FullNmae | cytochrome p450 oxidoreductase |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:9208 |
| EnsembleID | ENSG00000127948 |
| Uniprot | P16435 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| POR | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| POR | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| POR | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| POR | GO:0003958,GO:0003958,GO:0003958,GO:0005515,GO:0005789,GO:0005829,GO:0006805,GO:0009725,GO:0010181,GO:0016020,GO:0022900,GO:0032770,GO:0043231,GO:0050660,GO:0050661,GO:0090346 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ESR1 | POR | 21393444 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay,electrophoretic mobility shift assay | TFlink |
| ETS1 | POR | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMAD3 | POR | 21393444 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay | TFlink |
| SMAD4 | POR | 21393444 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay | TFlink |
| YBX1 | POR | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| THRA | POR | 21393444 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay,electrophoretic mobility shift assay | TFlink |
| THRB | POR | 21393444 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay | TFlink |
| SMARCA4 | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | POR | 10864447 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | POR | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SP1 | POR | 10864447 21900384 8660656 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| DAND5 | POR | 10864447 21900384 8660656 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | POR | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00002B7450 | POR | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000160683 | POR | 23905773 25416803 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NDUFB9 | POR | 25348397 | N/A | physical interaction | ComPPI |
| STAT1 | POR | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| CYCS | POR | 18230729 24234451 25348397 27898060 | N/A | physical interaction,enzymatic study | ComPPI,IntAct,OmniPath |
| HMOX1 | POR | 12626517 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| PLOD3 | POR | 25348397 | N/A | physical interaction | ComPPI |
| VAPA | POR | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | POR | 25348397 | N/A | physical interaction | ComPPI |
| XRCC6 | POR | 14525934 16169070 24234451 25348397 | physical association | two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| EVC2 | POR | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| EWSR1 | POR | 25348397 | N/A | physical interaction | ComPPI |
| XPO1 | POR | 25348397 | N/A | physical interaction | ComPPI |
| SYVN1 | POR | 25348397 | N/A | physical interaction | ComPPI |
| FANCC | POR | 25348397 27898060 9787138 | N/A | physical interaction | ComPPI,OmniPath |
| CYB5A | POR | 14525934 25348397 9398194 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| CYP17A1 | POR | 14525934 25348397 27898060 9888582 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD,OmniPath |
| INSIG1 | POR | 25348397 | N/A | physical interaction | ComPPI |
| DERL1 | POR | 25348397 | N/A | physical interaction | ComPPI |
| PGRMC1 | POR | 21081644 24234451 25348397 | colocalization,association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy | ComPPI,IntAct |
| CYP3A4 | POR | 25348397 | N/A | physical interaction | ComPPI |
| POR | CYP2E1 | 14525934 25348397 9398194 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| POR | SRPRB | 25348397 | N/A | physical interaction | ComPPI |
| POR | UBXN6 | 25348397 | N/A | physical interaction | ComPPI |
| POR | ATL3 | 25348397 | N/A | physical interaction | ComPPI |
| POR | NDUFV1 | 25348397 | N/A | physical interaction | ComPPI |
| POR | PLOD1 | 25348397 | N/A | physical interaction | ComPPI |
| POR | CTDNEP1 | 25348397 | N/A | physical interaction | ComPPI |
| WG | POR | 24234451 25348397 | physical association | experimental interaction detection,physical interaction | ComPPI,IntAct |
| PIP | POR | 14605208 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| POR | CYP4P2 | 14605208 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| POR | WNT5 | 25348397 | N/A | physical interaction | ComPPI |
| POR | WNT4 | 25348397 | N/A | physical interaction | ComPPI |
| WNT2 | POR | 25348397 | N/A | physical interaction | ComPPI |
