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GENE：CYB5R1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CYB5R1
FullNmae cytochrome b5 reductase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13397
EnsembleID ENSG00000159348
Uniprot Q9UHQ9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CYB5R1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CYB5R1 GO:0004128,GO:0005515,GO:0005739,GO:0005739,GO:0005739,GO:0005789,GO:0005829,GO:0005886,GO:0015701,GO:0016020,GO:0016126,GO:0031092,GO:0070062,GO:0071949

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CYB5R1 hsa:51706 path:hsa00520 Amino sugar and nucleotide sugar metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR CYB5R1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 CYB5R1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 CYB5R1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CYB5R1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CYB5R1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CYB5R1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CYB5R1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CYB5R1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CYB5R1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
SGTA CYB5R1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CYCS CYB5R1 14525934 25348397 9760250 N/A experimental interaction detection,in vitro ComPPI,HPRD
SLC7A1 CYB5R1 25348397 N/A physical interaction ComPPI
TTC1 CYB5R1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CYB5R1 UBC 25348397 N/A physical interaction ComPPI
CYB5R1 PRKN 25348397 N/A physical interaction ComPPI
CYB5R1 UBQLN1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CYB5R1 KCNA5 25348397 N/A physical interaction ComPPI
CYB5R1 IL20RA 25348397 N/A physical interaction ComPPI
CYB5R1 TMEM30A 25348397 N/A physical interaction ComPPI
CYB5R1 SIRT4 24234451 25348397 25525879 association anti tag coimmunoprecipitation ComPPI,IntAct
CYB5R1 COX6B1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct

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