Gene Information gene info

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GENE：FADS1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FADS1
FullNmae fatty acid desaturase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3574
EnsembleID ENSG00000149485
Uniprot O60427

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FADS1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FADS1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FADS1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FADS1 GO:0000248,GO:0005739,GO:0005789,GO:0005789,GO:0006355,GO:0006629,GO:0006636,GO:0006636,GO:0007267,GO:0008654,GO:0009267,GO:0016020,GO:0016020,GO:0016213,GO:0016491,GO:0016717,GO:0036109,GO:0042759,GO:0043231,GO:0043651,GO:0045485,GO:0045595,GO:0046456,GO:0062076

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FADS1 hsa:3992 path:hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human)
FADS1 hsa:3992 path:hsa01100 Metabolic pathways - Homo sapiens (human)
FADS1 hsa:3992 path:hsa01212 Fatty acid metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FADS1 DHCR7 17353931 23180781 physical association anti tag coimmunoprecipitation InnateDB
FADS1 PAAF1 17353931 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR FADS1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 FADS1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 FADS1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 FADS1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 FADS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FADS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FADS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FADS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 FADS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FADS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 FADS1 N/A rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 FADS1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS0000237AF9 FADS1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000F31F4 FADS1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 FADS1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000C85B2 FADS1 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000527B00 FADS1 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000355E82 FADS1 20371350 21572407 23446348 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000411752 FADS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002B7450 FADS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000018D2BE FADS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 FADS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 FADS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 FADS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF FADS1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 FADS1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00005F305A FADS1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001B12A4 FADS1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000331800 FADS1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000005481D FADS1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 FADS1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 FADS1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 FADS1 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CCDC22 FADS1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTH1R FADS1 25348397 N/A physical interaction ComPPI
SIRT2 FADS1 25348397 N/A physical interaction ComPPI
XRN1 FADS1 25348397 N/A physical interaction ComPPI
GRPR FADS1 25348397 N/A physical interaction ComPPI
HTR2C FADS1 25348397 N/A physical interaction ComPPI
TRIM25 FADS1 25348397 N/A physical interaction ComPPI
PAAF1 FADS1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TACR1 FADS1 25348397 N/A physical interaction ComPPI
FADS1 DHCR7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FADS1 GABRE 25348397 N/A physical interaction ComPPI
FADS1 RNF181 25348397 N/A physical interaction ComPPI
FADS1 GPR21 25348397 N/A physical interaction ComPPI
FADS1 SLC18A1 25348397 N/A physical interaction ComPPI
FADS1 UQCC1 25348397 N/A physical interaction ComPPI
FADS1 SLC39A12 25348397 N/A physical interaction ComPPI
FADS1 TMCO3 25348397 N/A physical interaction ComPPI
FADS1 ASPSCR1 25348397 N/A physical interaction ComPPI
FADS1 IL17RC 25348397 N/A physical interaction ComPPI

Visualization










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