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GENE：PTEN

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTEN
FullNmae phosphatase and tensin homolog
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9588
EnsembleID ENSG00000171862
Uniprot P60484

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTEN mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTEN immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTEN ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTEN apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTEN apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PTEN GO:0001933,GO:0001933,GO:0004438,GO:0004721,GO:0004722,GO:0004725,GO:0004725,GO:0005515,GO:0005576,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0005829,GO:0005886,GO:0005886,GO:0006470,GO:0006470,GO:0006470,GO:0006661,GO:0006915,GO:0007056,GO:0007270,GO:0007416,GO:0007417,GO:0007507,GO:0007611,GO:0007626,GO:0008284,GO:0008285,GO:0008285,GO:0008285,GO:0008289,GO:0009898,GO:0010719,GO:0010975,GO:0010977,GO:0010997,GO:0014069,GO:0016314,GO:0016314,GO:0016314,GO:0016324,GO:0016477,GO:0016605,GO:0017018,GO:0019899,GO:0021542,GO:0021955,GO:0030165,GO:0030336,GO:0031647,GO:0032286,GO:0032535,GO:0033137,GO:0033555,GO:0035176,GO:0035749,GO:0042802,GO:0042995,GO:0042995,GO:0043005,GO:0043197,GO:0043220,GO:0043491,GO:0043491,GO:0045475,GO:0045736,GO:0045792,GO:0046621,GO:0046856,GO:0046856,GO:0046856,GO:0048853,GO:0048854,GO:0048870,GO:0050771,GO:0050821,GO:0051091,GO:0051548,GO:0051717,GO:0051800,GO:0051800,GO:0051895,GO:0051896,GO:0051898,GO:0051898,GO:0051898,GO:0051898,GO:0052866,GO:0060024,GO:0060070,GO:0060074,GO:0060134,GO:0060997,GO:0061002,GO:0070373,GO:0071257,GO:0090394,GO:0097105,GO:0097107,GO:1902807,GO:1903690,GO:1903984,GO:1904668,GO:1904706,GO:1990381,GO:2000060,GO:2000134,GO:2000463,GO:2000773,GO:2000808

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PTEN hsa:5728 path:hsa00562 Inositol phosphate metabolism - Homo sapiens (human)
PTEN hsa:5728 path:hsa01100 Metabolic pathways - Homo sapiens (human)
PTEN hsa:5728 path:hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human)
PTEN hsa:5728 path:hsa04068 FoxO signaling pathway - Homo sapiens (human)
PTEN hsa:5728 path:hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human)
PTEN hsa:5728 path:hsa04071 Sphingolipid signaling pathway - Homo sapiens (human)
PTEN hsa:5728 path:hsa04115 p53 signaling pathway - Homo sapiens (human)
PTEN hsa:5728 path:hsa04140 Autophagy - animal - Homo sapiens (human)
PTEN hsa:5728 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
PTEN hsa:5728 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
PTEN hsa:5728 path:hsa04218 Cellular senescence - Homo sapiens (human)
PTEN hsa:5728 path:hsa04510 Focal adhesion - Homo sapiens (human)
PTEN hsa:5728 path:hsa04931 Insulin resistance - Homo sapiens (human)
PTEN hsa:5728 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
PTEN hsa:5728 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
PTEN hsa:5728 path:hsa05200 Pathways in cancer - Homo sapiens (human)
PTEN hsa:5728 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)
PTEN hsa:5728 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
PTEN hsa:5728 path:hsa05213 Endometrial cancer - Homo sapiens (human)
PTEN hsa:5728 path:hsa05214 Glioma - Homo sapiens (human)
PTEN hsa:5728 path:hsa05215 Prostate cancer - Homo sapiens (human)
PTEN hsa:5728 path:hsa05218 Melanoma - Homo sapiens (human)
PTEN hsa:5728 path:hsa05222 Small cell lung cancer - Homo sapiens (human)
PTEN hsa:5728 path:hsa05224 Breast cancer - Homo sapiens (human)
PTEN hsa:5728 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
PTEN hsa:5728 path:hsa05230 Central carbon metabolism in cancer - Homo sapiens (human)
PTEN hsa:5728 path:hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human)
PTEN hsa:5728 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PTEN ETS2 10753747 11747822 12040186 15721744 16288286 16982858 17218262 19847259 22179046 22465479 23732914 24254977 25364523 26192618 interaction type N/A ACSN
PTP4A3 PTEN 22677902 23691193 24376839 24686170 26192618 interaction type N/A ACSN
PTEN AKT1 10753747 11747822 12040186 12592338 15721744 16288286 16982858 17218262 17409395 19440036 19847259 19945467 20609352 21084277 22179046 22465479 23331499 23732914 24030100 24254977 25364523 26192618 26597054 27328425 27572739 interaction type N/A ACSN,SignaLink,SignaLink
ROCK1 PTEN 10652353 11698448 12194823 12778124 19349987 20008297 22074495 26192618 27785353 interaction type N/A ACSN
SNAI1 PTEN 10048576 11283614 11708773 12490555 12545156 12668723 14623871 14673164 15111329 15151915 15155580 15181457 15448698 15459715 16001073 16079281 16232121 16510505 16556862 16617148 16716598 16831886 17018611 17055429 17093497 17403902 17490644 17537911 17550342 17563753 17615296 17671186 18172008 18297062 18832382 19208835 19412634 19564415 19597490 19935649 20027199 20702634 20706219 20713526 20731704 21041997 21051859 21159887 21199805 21317430 21577210 21685935 21883379 2191300 22006115 22286765 22406545 22439866 22514743 22796940 22945800 23140366 23869868 26192618 8844971 9157999 9618481 interaction type N/A ACSN
PTEN GRB2 10648629 10753747 11747822 12040186 15584861 15721744 16288286 16982858 17218262 19847259 22179046 22465479 23732914 24254977 25364523 26192618 interaction type N/A ACSN
PTEN GAB1 10648629 10753747 11747822 12040186 15584861 15721744 16288286 16982858 17218262 19847259 22179046 22465479 23732914 24254977 25364523 26192618 interaction type N/A ACSN
FRK PTEN 17218260 17218261 19597351 19652529 26192618 interaction type N/A ACSN
NEDD4 PTEN 17218260 17218261 17996703 18498243 18562292 19345329 19652529 21071413 22679284 23331499 26192618 interaction type,stimulation N/A ACSN,SignaLink,SignaLink
PTEN RAD51 10753747 11747822 12040186 15721744 16288286 16982858 17218252 17218262 18716620 19847259 22179046 22465479 23732914 24254977 25364523 26192618 interaction type N/A ACSN
RHOA PTEN 10953004 11698448 11729192 11739775 11992112 12194823 12361600 12740575 12778124 14657501 14744429 15761148 15764699 15793569 15803130 17517963 18037882 18423981 20008297 20351293 20535745 21178402 21642958 21840487 22244698 22949611 23109003 24857661 24919149 26192618 26885855 27048821 27066895 7479854 9362522 9660866 9822605 interaction type,chemical activation reaction N/A ACSN,SignaLink
CTNNB1 PTEN 16219695 23180781 physical association anti tag coimmunoprecipitation InnateDB
PPP1CA PTEN 17274640 23180781 physical association anti tag coimmunoprecipitation InnateDB
PTEN POLR2F 23180781 23994473 physical association anti tag coimmunoprecipitation InnateDB
EZH2 PTEN 23180781 25955299 physical association anti tag coimmunoprecipitation InnateDB
PTEN PTEN 18794881 22413754 26467481 interaction type,dephosphorylation reaction,up-regulates activity,down-regulates activity N/A Signor
PTEN PDPK1 11943559 23331499 stimulation N/A SignaLink,SignaLink
PTEN AKT2 10970827 23331499 inhibition N/A SignaLink,SignaLink
PTEN AKT3 10644997 23331499 stimulation N/A SignaLink
PTEN RAC1 10753747 23331499 stimulation N/A SignaLink
CDC42 PTEN 16381926 23331499 stimulation N/A SignaLink
PTEN PTK2 10400703 23109003 inhibition N/A SignaLink
PTEN CBL 23109003 23118026 chemical activation reaction N/A SignaLink
CBLB PTEN 22763434 23109003 chemical activation reaction N/A SignaLink

Source Target Pmid Interactiontype Methods Database
CAV1 PTEN 20005715 interaction type N/A PSP
MAGI2 PTEN 20005715 interaction type N/A PSP
PXN PTEN 20005715 interaction type N/A PSP
SLC9A3R1 PTEN 20005715 interaction type N/A PSP
CAV1 PTEN 12176037 20005715 21071413 N/A N/A SignaLink
MAGI2 PTEN 10760291 18988627 20005715 N/A N/A SignaLink
PXN PTEN 11857088 20005715 21071413 N/A N/A SignaLink
SLC9A3R1 PTEN 20005715 21071413 21990315 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 PTEN 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
RBPJ PTEN 17245125 19479935 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
MYC PTEN 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 PTEN 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PTEN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PTEN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PTEN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PTEN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PTEN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PTEN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PTEN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PTEN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 PTEN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PTEN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR PTEN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
AR PTEN 20729295 21532617 23418309 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PTEN 17516844 20514024 20959484 trascriptional regulation,stimulation inferred by curator TFlink
EZH2 PTEN 22956625 trascriptional regulation,stimulation inferred by curator TFlink
GATD3B PTEN 18414037 trascriptional regulation,stimulation inferred by curator TFlink
HES1 PTEN 18414037 trascriptional regulation,stimulation inferred by curator TFlink
MTA1 PTEN 22700976 trascriptional regulation,stimulation inferred by curator TFlink
MXD1 PTEN 17998413 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 PTEN 17334236 19940030 trascriptional regulation,stimulation inferred by curator TFlink
PPARG PTEN 11378386 16425225 16775433 20198337 trascriptional regulation,stimulation inferred by curator TFlink
RELA PTEN 17334236 19940030 trascriptional regulation,stimulation inferred by curator TFlink
SALL4 PTEN 19440552 trascriptional regulation,stimulation inferred by curator TFlink
SP1 PTEN 22030357 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 PTEN 22030357 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 PTEN 22055460 trascriptional regulation,stimulation inferred by curator TFlink
TCF7L2 PTEN 21132538 trascriptional regulation,stimulation inferred by curator TFlink
TCF4 PTEN 21132538 trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A PTEN 18316341 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PTEN 11545734 17344317 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000600E6 PTEN 21283765 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS000008F0CF PTEN 22593189 rna interference,inhibition western blot miRSponge
URS000003E1A9 PTEN 20053927 rna interference,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay miRSponge
URS00002E92A8 PTEN 23125220 rna interference,inhibition western blot,rna immunoprecipitation,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00002075FA PTEN 20008935 20227518 21283765 23418359 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000035CC3E PTEN 20008935 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000006FDD4 PTEN N/A 14697198 18460397 21853360 \N rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000042E1F PTEN 20008935 21283765 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000009262D PTEN N/A 16762633 17681183 18850008 19072831 19253296 19641183 19672202 19906824 20048743 20216554 20223231 20797623 20813833 20978511 21544242 22267008 22761812 22770403 22879939 22956424 23226804 \N rna interference,inhibition array technology,experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,immunocytochemistry,miRNA interference luciferase reporter assay miRSponge
URS0000160683 PTEN N/A 18199536 20548023 21228352 \N rna interference,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000013ABA3 PTEN 20216554 23471579 \N rna interference,inhibition western blot,miRNA interference luciferase reporter assay miRSponge
URS0000060B2B PTEN 20216554 23471579 \N rna interference,inhibition western blot,miRNA interference luciferase reporter assay miRSponge
URS0000170CF4 PTEN 19962668 20618998 23372675 rna interference,inhibition experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS0000153377 PTEN 19962668 20618998 23028614 rna interference,inhibition experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS00001CC864 PTEN 23019365 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000183BED PTEN 23189187 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000076995 PTEN 21573166 23426367 rna interference,inhibition experimental interaction detection,miRNA interference luciferase reporter assay miRSponge
URS0000535FDD PTEN 20006626 22544933 rna interference,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000037D7E5 PTEN 22262409 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000298BA3 PTEN 22262409 rna interference,inhibition western blot,miRNA interference luciferase reporter assay miRSponge
URS00000DDD35 PTEN 22465665 rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr miRSponge
URS000006FDD4 PTEN 14697198 18460397 18927107 20388916 21853360 22473208 22743998 23603256 23824915 24220575 25416803 26098000 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay miR2Disease,miRDeathDB,TarBase
URS000009262D PTEN 16762633 17478730 17681183 18460397 18850008 18927107 19072831 19175831 19253296 19342589 19473551 19641183 19672202 19730150 19906824 20048743 20216554 20223231 20797623 20813833 20978511 21187093 21544242 21820606 22267008 22678116 22743998 22761812 22770403 22879939 22956257 22956424 23174819 23226804 23275230 23446999 23466500 23548551 23643356 23708209 23811941 23981302 24154840 24161401 24356956 24468088 24603539 24659669 24817011 24912785 25361012 25416803 25799148 25803229 25963606 26284486 26387848 26559642 26568302 26741162 26847601 26864640 26975392 27350731 27574331 27611950 27725205 27811366 28069514 28407783 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,immunocytochemistry,miRNA interference luciferase reporter assay miR2Disease,miRDeathDB,TarBase
URS0000160683 PTEN 18199536 18927107 20548023 21228352 21688200 22502680 22743998 23834902 25361012 25416803 27339596 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunocytochemistry,miRNA interference luciferase reporter assay miR2Disease,miRDeathDB,TarBase
URS0000170CF4 PTEN 19962668 20618998 22743998 23372675 24286315 25416803 26501139 26538296 27644883 mrna cleavage,inhibition experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRDeathDB,TarBase
URS0000153377 PTEN 19962668 20618998 22743998 23028614 23974492 23994196 25416803 27644883 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay miRDeathDB,TarBase
URS000013ABA3 PTEN 18927107 19543271 20216554 23471579 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS0000060B2B PTEN 18927107 19543271 20216554 23471579 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS00002075FA PTEN 20008935 20227518 20388916 21283765 22473208 23391506 23418359 23433743 24220575 24462867 24901013 24912422 25416803 26318586 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS0000535FDD PTEN 20006626 22544933 25416803 25662849 26045065 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000003E1A9 PTEN 20053927 23592263 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,clip,miRNA interference luciferase reporter assay TarBase
URS0000042E1F PTEN 20008935 21283765 22473208 25416803 26318586 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS000035CC3E PTEN 20008935 23511639 25416803 27291152 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00000600E6 PTEN 21283765 22473208 24842611 25041637 25416803 26238857 26318586 27270534 28288092 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,clip,miRNA interference luciferase reporter assay TarBase
URS0000298BA3 PTEN 22262409 22473208 25416803 mrna cleavage,inhibition western blot,clip,miRNA interference luciferase reporter assay TarBase
URS00000DDD35 PTEN 22465665 22473208 25416803 25823655 26087719 27119510 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000037D7E5 PTEN 22262409 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000008F0CF PTEN 22593189 25416803 mrna cleavage,inhibition western blot TarBase
URS0000096022 PTEN 20388916 25416803 26544868 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000C85B2 PTEN 20388916 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00001CC864 PTEN 23019365 24101522 24317043 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000076995 PTEN 21573166 23426367 23994196 25416803 26199111 27523474 27548517 mrna cleavage,inhibition array technology,experimental interaction detection,nucleotide sequence identification,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000183BED PTEN 23189187 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00002E92A8 PTEN 23125220 25416803 mrna cleavage,inhibition western blot,rna immunoprecipitation,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000039E1E1 PTEN 24108762 25416803 26097565 26306906 27510094 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000AA464 PTEN 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001CC379 PTEN 24867318 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000272A3D PTEN 23143395 25416803 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000048BA36 PTEN 24571667 25416803 mrna cleavage,inhibition western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000013E79D PTEN 24914051 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00001DA458 PTEN 22660396 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS00002FC5B0 PTEN 22473208 23524257 23617834 24123284 25416803 28319142 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000008DA94 PTEN 23592263 24413994 25416803 27983967 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00002C0FCB PTEN 24220575 25416803 25637514 26837847 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00001C11BC PTEN 24315818 25416803 26837847 27230112 27855389 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00002B3783 PTEN 22473208 23945289 25364498 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00004AC389 PTEN 23384558 24100613 25416803 27113763 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000338542 PTEN 23684381 25416803 27811366 28132399 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS0000016914 PTEN 23564023 23856247 24084898 25416803 25973003 27974696 mrna cleavage,inhibition experimental interaction detection,western blot,chromatin immunoprecipitation assay,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000055BBE5 PTEN 24866238 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS000016D2D4 PTEN 24100613 25416803 26317552 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS00001A7F58 PTEN 22473208 24099768 25416803 28337377 mrna cleavage,inhibition western blot,clip,miRNA interference luciferase reporter assay TarBase
URS000003ABC4 PTEN 24140453 24161401 25416803 26538296 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00003CF1AD PTEN 24161401 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000019F055 PTEN 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00000EED18 PTEN 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002A79D1 PTEN 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000759B6A PTEN 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 PTEN 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000002CF68 PTEN 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004C5774 PTEN 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000045B99E PTEN 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 PTEN 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 PTEN 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000046CDA6 PTEN 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 PTEN 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000015D23B PTEN 19536157 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C0D3F PTEN 19536157 23824327 25416803 27292025 27517917 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip TarBase
URS0000013DD8 PTEN 19536157 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000015188E PTEN 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 PTEN 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000007F792 PTEN 23824327 25416803 25998046 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000251D0B PTEN 25416803 26837847 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000315338 PTEN 25416803 26458524 27040383 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001E0AEA PTEN 25416803 27796281 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000367985 PTEN 25416803 26753960 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000FFE5F PTEN 25416803 26692329 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00004900F1 PTEN 25416803 27499479 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS0000070CD2 PTEN 25416803 26890744 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS000018C928 PTEN 25416803 25695913 mrna cleavage,inhibition experimental interaction detection,western blot,miRNA interference luciferase reporter assay TarBase
URS0000171525 PTEN 25416803 28008308 28029649 28411308 mrna cleavage,inhibition array technology,western blot,miRNA interference luciferase reporter assay TarBase
URS00000EC1BE PTEN 25416803 27533461 mrna cleavage,inhibition experimental interaction detection,western blot,rna immunoprecipitation,miRNA interference luciferase reporter assay TarBase
URS0000277201 PTEN 25416803 26544868 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000000C73C PTEN 25416803 27508033 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 PTEN 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
FRK PTEN 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
SRC PTEN 22135298 phosphorylation N/A PhosphoSite
STK11 PTEN 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
GSK3B PTEN 22135298 phosphorylation N/A PhosphoSite
LCK PTEN 22135298 phosphorylation N/A PhosphoSite
PLK1 PTEN 22135298 phosphorylation N/A PhosphoSite
FGFR3 PTEN 22135298 phosphorylation N/A PhosphoSite
ROCK1 PTEN 22135298 phosphorylation N/A PhosphoSite
INSR PTEN 22135298 phosphorylation N/A PhosphoSite
ATM PTEN 22135298 phosphorylation N/A PhosphoSite
PRKCZ PTEN 22135298 phosphorylation N/A PhosphoSite
PLK3 PTEN 22135298 phosphorylation N/A PhosphoSite
FGFR2 PTEN 22135298 phosphorylation N/A PhosphoSite
LYN PTEN 22135298 phosphorylation N/A PhosphoSite
NEDD4 PTEN 25361965 interaction type N/A PTMCode2
PTEN NEDD4 25361965 interaction type N/A PTMCode2
PTEN AR 25361965 interaction type N/A PTMCode2
AR PTEN 25361965 interaction type N/A PTMCode2
PTEN PINK1 25361965 interaction type N/A PTMCode2
PINK1 PTEN 25361965 interaction type N/A PTMCode2
PTEN PIK3CD 25361965 interaction type N/A PTMCode2
PIK3CD PTEN 25361965 interaction type N/A PTMCode2
PTEN SLC9A3R2 25361965 interaction type N/A PTMCode2
SLC9A3R2 PTEN 25361965 interaction type N/A PTMCode2
MVP PTEN 25361965 interaction type N/A PTMCode2
PTEN MVP 25361965 interaction type N/A PTMCode2
PIK3CA PTEN 25361965 interaction type N/A PTMCode2
PTEN PIK3CA 25361965 interaction type N/A PTMCode2
PTEN CSNK2A1 25361965 interaction type N/A PTMCode2
UBE2L3 PTEN 25361965 interaction type N/A PTMCode2
PTEN UBE2L3 25361965 interaction type N/A PTMCode2
IGF1R PTEN 25361965 interaction type N/A PTMCode2
PTEN IGF1R 25361965 interaction type N/A PTMCode2
CSNK2A2 PTEN 25361965 interaction type N/A PTMCode2
PTEN CSNK2A2 25361965 interaction type N/A PTMCode2
TP53 PTEN 25361965 interaction type N/A PTMCode2
PTEN TP53 25361965 interaction type N/A PTMCode2
CSF1R PTEN 25361965 interaction type N/A PTMCode2
PTEN CSF1R 25361965 interaction type N/A PTMCode2
AKT1 PTEN 25361965 interaction type N/A PTMCode2
PTEN AKT1 25361965 interaction type N/A PTMCode2
PTEN STK11 25361965 interaction type N/A PTMCode2
MAGI2 PTEN 25361965 interaction type N/A PTMCode2
PTEN MAGI2 25361965 interaction type N/A PTMCode2
SLC9A3R1 PTEN 25361965 interaction type N/A PTMCode2
PTEN SLC9A3R1 25361965 interaction type N/A PTMCode2
PTEN FRK 25361965 interaction type N/A PTMCode2
MAGI3 PTEN 25361965 interaction type N/A PTMCode2
PTEN MAGI3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PPL PTEN 25348397 N/A physical interaction ComPPI
PIK3R2 PTEN 25348397 N/A physical interaction ComPPI
UBE2I PTEN 12620973 14525934 22713753 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
YES1 PTEN 25348397 N/A physical interaction ComPPI
HSPA8 PTEN 25348397 N/A physical interaction ComPPI
HSPA2 PTEN 25348397 N/A physical interaction ComPPI
ANP32B PTEN 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
LDHB PTEN 25348397 N/A physical interaction ComPPI
CFL1 PTEN 25348397 N/A physical interaction ComPPI
TUBB PTEN 25348397 N/A physical interaction ComPPI
AMOT PTEN 25348397 N/A physical interaction ComPPI
NGB PTEN 25348397 N/A physical interaction ComPPI
CALM1 PTEN 25348397 N/A physical interaction ComPPI
RPS26 PTEN 25348397 N/A physical interaction ComPPI
SKP1 PTEN 25348397 N/A physical interaction ComPPI
XIAP PTEN 25348397 N/A physical interaction ComPPI
BMI1 PTEN 19903340 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,cross-linking study,physical interaction,fluorescence microscopy ComPPI,IntAct
HBA1 PTEN 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HSP90AB1 PTEN 25348397 N/A physical interaction ComPPI
TUFM PTEN 25348397 N/A physical interaction ComPPI
BEX1 PTEN 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RPL10A PTEN 25348397 N/A physical interaction ComPPI
CBL PTEN 25348397 N/A physical interaction ComPPI
PTK2B PTEN 25348397 N/A physical interaction ComPPI
CRKL PTEN 25348397 N/A physical interaction ComPPI
FBXW7 PTEN 25348397 N/A physical interaction ComPPI
INS PTEN 25348397 N/A physical interaction ComPPI
AR PTEN 14525934 15205473 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NCOA3 PTEN 23514585 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
USP7 PTEN 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,physical interaction ComPPI
SLC9A3R1 PTEN 14525934 16456542 21804599 24012959 24234451 25348397 physical association two hybrid,experimental interaction detection,filter binding,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
KAT2B PTEN 25348397 N/A physical interaction ComPPI
FZR1 PTEN 25348397 N/A physical interaction ComPPI
UBE2D2 PTEN 24234451 24656772 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
UBE2L3 PTEN 12620973 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RHOA PTEN 25348397 N/A physical interaction ComPPI
PKN2 PTEN 25348397 N/A physical interaction ComPPI
WWP1 PTEN 25348397 N/A physical interaction ComPPI
SLC9A3R2 PTEN 14525934 16456542 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,filter binding,pull down,in vivo ComPPI,HPRD,IntAct
JUP PTEN 25348397 N/A physical interaction ComPPI
GPC4 PTEN 25348397 N/A physical interaction ComPPI
PDGFRB PTEN 16456542 24012959 24234451 25241761 25348397 association,physical association filter binding,pull down,physical interaction,proximity ligation assay ComPPI,IntAct
TUBA1B PTEN 25348397 N/A physical interaction ComPPI
IRS4 PTEN 25348397 N/A physical interaction ComPPI
MVP PTEN 12177006 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
UBB PTEN 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,comigration in sds page ComPPI
UBC PTEN 18562292 19473982 24798731 25348397 27898060 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,comigration in sds page ComPPI,OmniPath
RPS27A PTEN 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,physical interaction,comigration in sds page ComPPI
UBA52 PTEN 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,comigration in sds page ComPPI
P3H4 PTEN 25348397 N/A physical interaction ComPPI
HSP90AA1 PTEN 25348397 N/A physical interaction ComPPI
PDGFRA PTEN 25348397 N/A physical interaction ComPPI
CDH1 PTEN 25348397 N/A physical interaction ComPPI
EIF2AK2 PTEN 25348397 N/A physical interaction ComPPI
WWP2 PTEN 25348397 N/A physical interaction ComPPI
CAV1 PTEN 12176037 14525934 24234451 25348397 colocalization,physical association coimmunoprecipitation,cosedimentation through density gradient,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
STIP1 PTEN 25348397 N/A physical interaction ComPPI
HSPA5 PTEN 18064632 24234451 25348397 colocalization cosedimentation,cosedimentation in solution ComPPI,IntAct
HSPA1A PTEN 25348397 N/A physical interaction ComPPI
HSPA1B PTEN 25348397 N/A physical interaction ComPPI
POLDIP2 PTEN 25348397 N/A physical interaction ComPPI
PRDX1 PTEN 19369943 24234451 25348397 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct,OmniPath
PLK1 PTEN 25348397 N/A anti bait coimmunoprecipitation,physical interaction,physical interaction ComPPI
CASP8 PTEN 25348397 N/A physical interaction ComPPI
PPP1CA PTEN 14525934 17274640 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,antibody array ComPPI,HPRD,IntAct
STAT5A PTEN 25348397 N/A genetic ComPPI
PXN PTEN 23397142 24234451 25348397 physical association physical interaction,in vivo,proximity ligation assay ComPPI,IntAct
HNRNPU PTEN 25348397 N/A physical interaction ComPPI
MAGI3 PTEN 10748157 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
PLEC PTEN 25348397 N/A physical interaction ComPPI
CSNK2A1 PTEN 12297295 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
AKAP12 PTEN 25348397 N/A physical interaction ComPPI
NME1 PTEN 25348397 N/A physical interaction ComPPI
TXN PTEN 25348397 N/A physical interaction ComPPI
HNRNPL PTEN 25348397 N/A physical interaction ComPPI
UHRF2 PTEN 21952639 24234451 25348397 physical association antibody array ComPPI,IntAct
NCF1 PTEN 25348397 N/A physical interaction ComPPI
SDC4 PTEN 25348397 N/A physical interaction ComPPI
SPTAN1 PTEN 25348397 N/A physical interaction ComPPI
PKM PTEN 25348397 N/A physical interaction ComPPI
ANG PTEN 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SDCBP PTEN 25348397 N/A physical interaction ComPPI
UTRN PTEN 25348397 N/A physical interaction ComPPI
USP4 PTEN 25348397 N/A physical interaction ComPPI
FRK PTEN 19345329 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,protein kinase assay ComPPI,IntAct
RPS6 PTEN 25348397 N/A physical interaction ComPPI
RPS25 PTEN 25348397 N/A physical interaction ComPPI
USP13 PTEN 24270891 25348397 26280536 26453058 27898060 N/A anti bait coimmunoprecipitation,physical interaction ComPPI,OmniPath
RPL12 PTEN 25348397 N/A physical interaction ComPPI
RPS13 PTEN 25348397 N/A physical interaction ComPPI
RPLP0 PTEN 25348397 N/A physical interaction ComPPI
RPLP2 PTEN 25348397 N/A physical interaction ComPPI
CCNE2 PTEN 25348397 N/A physical interaction ComPPI
DLG1 PTEN 10646847 14525934 25348397 N/A anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
CSNK2A2 PTEN 12297295 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SPTBN1 PTEN 25348397 N/A physical interaction ComPPI
EGFR PTEN 25348397 N/A physical interaction ComPPI
SDC1 PTEN 25348397 N/A physical interaction ComPPI
ANXA2 PTEN 25348397 N/A physical interaction ComPPI
MCRS1 PTEN 25348397 N/A physical interaction ComPPI
MAP2K6 PTEN 25348397 N/A physical interaction ComPPI
EPHB1 PTEN 25348397 N/A physical interaction ComPPI
AMHR2 PTEN 25348397 N/A physical interaction ComPPI
CTNNB1 PTEN 20123964 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
USP8 PTEN 25348397 N/A physical interaction ComPPI
TUBB4B PTEN 25348397 N/A physical interaction ComPPI
PTEN MAGI2 10760291 14525934 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
PTEN MAST2 14525934 15951562 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
PTEN MAST1 14525934 15951562 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
PTEN STK11 14525934 15987703 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
PTEN UTP14A 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PTEN COPS6 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PTEN CHGB 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PTEN MAST3 14525934 15951562 24234451 25348397 phosphorylation reaction,physical association beta galactosidase complementation,two hybrid,experimental interaction detection,pull down,protein kinase assay,in vitro,two hybrid ComPPI,HPRD,IntAct
PTEN AKT1 10866658 12077256 12297295 14525934 25348397 N/A experimental interaction detection,physical interaction,genetic,in vitro,in vivo ComPPI,HPRD
PTEN ESR1 25348397 N/A physical interaction ComPPI
PTEN TP53 12620407 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PTEN PTK2 23397142 24234451 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
PTEN NEDD4 19345329 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PTEN NDFIP1 20534535 22213801 23012657 24798731 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PTEN NDFIP2 25348397 N/A physical interaction ComPPI
PTEN PTPA 25348397 N/A physical interaction ComPPI
PTEN WNT4 25348397 N/A physical interaction ComPPI
PTEN QRFPR 25348397 N/A physical interaction ComPPI
PTEN ARHGAP26 25348397 N/A physical interaction ComPPI
PTEN G3BP2 25348397 N/A physical interaction ComPPI
PTEN CENPC 25348397 N/A physical interaction ComPPI
PTEN DBF4B 25348397 N/A physical interaction ComPPI
PTEN INHBE 25348397 N/A physical interaction ComPPI
PTEN GFRA2 25348397 N/A physical interaction ComPPI
PTEN SMTN 25348397 N/A physical interaction ComPPI
PTEN KRT14 25348397 N/A physical interaction ComPPI
PTEN PINK1 25348397 N/A physical interaction ComPPI
PTEN PTPN14 25348397 N/A physical interaction ComPPI
PTEN ELOA3P 25348397 N/A physical interaction ComPPI
PTEN BAP1 25348397 N/A physical interaction ComPPI
PTEN MED12 25348397 N/A physical interaction ComPPI
PTEN ZNF787 25348397 N/A physical interaction ComPPI
PTEN FBN2 25348397 N/A physical interaction ComPPI
PTEN TTBK2 25348397 N/A physical interaction ComPPI
PTEN PPP3CA 25348397 N/A physical interaction ComPPI
PTEN EGR1 25348397 N/A physical interaction ComPPI
PTEN STUB1 25348397 N/A physical interaction ComPPI
PTEN ELAVL1 25348397 N/A physical interaction ComPPI
PTEN SHARPIN 20458142 25152374 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PTEN PARK7 19885556 21426932 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PTEN CDC27 21241890 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
PTEN ANAPC4 21241890 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTEN ANAPC5 21241890 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTEN ANAPC7 21241890 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTEN LATS1 25348397 N/A physical interaction ComPPI
PTEN USP10 25348397 N/A physical interaction ComPPI
PTEN USP39 25348397 N/A physical interaction ComPPI
PTEN TNKS 25348397 N/A physical interaction ComPPI
PTEN TNKS2 25348397 N/A physical interaction ComPPI
PTEN RNF146 25348397 N/A physical interaction ComPPI
PTEN ACACA 25348397 N/A physical interaction ComPPI
PTEN PC 25348397 N/A physical interaction ComPPI
PTEN PCCA 25348397 N/A physical interaction ComPPI
PTEN PCCB 25348397 N/A physical interaction ComPPI
PTEN MCCC2 25348397 N/A physical interaction ComPPI
PTEN MCCC1 25348397 N/A physical interaction ComPPI
PTEN DBT 25348397 N/A physical interaction ComPPI
PTEN HSP90AA2P 25348397 N/A physical interaction ComPPI
PTEN TUBA3C 25348397 N/A physical interaction ComPPI
PTEN HSPA1L 25348397 N/A physical interaction ComPPI
PTEN TUBB2A 25348397 N/A physical interaction ComPPI
PTEN ETS1 25348397 N/A physical interaction ComPPI
PTEN HSPA6 25348397 N/A physical interaction ComPPI
PTEN ACACB 25348397 N/A physical interaction ComPPI
PTEN BCKDHA 25348397 N/A physical interaction ComPPI
PTEN TUBA1C 25348397 N/A physical interaction ComPPI
PTEN PPP1R10 25348397 N/A physical interaction ComPPI
PTEN MC1R 25348397 N/A physical interaction ComPPI
PTEN TUBB3 25348397 N/A physical interaction ComPPI
PTEN CXCL1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTEN IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTEN OSGIN1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTEN RPS2 25348397 N/A physical interaction ComPPI
PTEN RPLP0P6 25348397 N/A physical interaction ComPPI
PTEN SSR4 25348397 N/A physical interaction ComPPI
PTEN ANXA2P2 25348397 N/A physical interaction ComPPI
PTEN FASN 25348397 N/A physical interaction ComPPI
PTEN DBN1 23940795 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,fluorescent resonance energy transfer,physical interaction ComPPI,IntAct,OmniPath
PTEN DSP 25348397 N/A physical interaction ComPPI
PTEN HSD17B1 25348397 N/A physical interaction ComPPI
PTEN RPS9 25348397 N/A physical interaction ComPPI
PTEN RPL38 25348397 N/A physical interaction ComPPI
PTEN GNAI1 25348397 N/A physical interaction ComPPI
PTEN GNAI2 25348397 N/A physical interaction ComPPI
PTEN MPRIP 25348397 N/A physical interaction ComPPI
PTEN RPS15A 25348397 N/A physical interaction ComPPI
PTEN GSTM2 25348397 N/A physical interaction ComPPI
PTEN EEF2 25348397 N/A physical interaction ComPPI
PTEN GNB4 25348397 N/A physical interaction ComPPI
PTEN RPL27 25348397 N/A physical interaction ComPPI
PTEN ITPRID2 25348397 N/A physical interaction ComPPI
PTEN DNAJA1 25348397 N/A physical interaction ComPPI
PTEN LIMA1 25348397 N/A physical interaction ComPPI
PTEN RPL22L1 25348397 N/A physical interaction ComPPI
PTEN RPL27A 25348397 N/A physical interaction ComPPI
PTEN FLNB 25348397 N/A physical interaction ComPPI
PTEN MYO1D 25348397 N/A physical interaction ComPPI
PTEN MTHFD2 25348397 N/A physical interaction ComPPI
PTEN RPS17 25348397 N/A physical interaction ComPPI
PTEN RCC2 25348397 N/A physical interaction ComPPI
PTEN MYOF 25348397 N/A physical interaction ComPPI
PTEN GPC1 25348397 N/A physical interaction ComPPI
PTEN RPL7 25348397 N/A physical interaction ComPPI
PTEN ATP5F1C 25348397 N/A physical interaction ComPPI
PTEN RPL13A 25348397 N/A physical interaction ComPPI
PTEN NCF1B 25348397 N/A physical interaction ComPPI
PTEN RPS20 25348397 N/A physical interaction ComPPI
PTEN RPS27 25348397 N/A physical interaction ComPPI
PTEN H2AC4 25348397 N/A physical interaction ComPPI
PTEN S100A8 25348397 N/A physical interaction ComPPI
PTEN MYH10 25348397 N/A physical interaction ComPPI
PTEN HSPD1 25348397 N/A physical interaction ComPPI
PTEN ATP5F1A 25348397 N/A physical interaction ComPPI
PTEN KBTBD4 25348397 N/A physical interaction ComPPI
PTEN RPS4X 25348397 N/A physical interaction ComPPI
PTEN SLC25A5 25348397 N/A physical interaction ComPPI
PTEN DCAF11 25348397 N/A physical interaction ComPPI
PTEN S100A9 25348397 N/A physical interaction ComPPI
PTEN LGALS1 25348397 N/A physical interaction ComPPI
PTEN MYO1B 25348397 N/A physical interaction ComPPI
PTEN RPS3 25348397 N/A physical interaction ComPPI
PTEN MYL12B 25348397 N/A physical interaction ComPPI
PTEN MYL12A 25348397 N/A physical interaction ComPPI
PTEN SLC25A3 25348397 N/A physical interaction ComPPI
PTEN RPL31 25348397 N/A physical interaction ComPPI
PTEN SNTB2 25348397 N/A physical interaction ComPPI
PTEN MYO1C 25348397 N/A physical interaction ComPPI
PTEN SETX 25348397 N/A physical interaction ComPPI
PTEN RPL13 25348397 N/A physical interaction ComPPI
PTEN METTL26 25348397 N/A physical interaction ComPPI
PTEN DDB1 25348397 N/A physical interaction ComPPI
PTEN OTUD3 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,physical interaction ComPPI
PTEN PBK 25348397 N/A physical interaction ComPPI
PTEN BCAR1 25348397 N/A physical interaction ComPPI
PTEN SPOP 24234451 24656772 25348397 ubiquitination reaction,physical association anti tag coimmunoprecipitation,x-ray crystallography,physical interaction,ubiquitinase assay ComPPI,IntAct
PTEN PLEKHA1 25348397 N/A physical interaction ComPPI
PTEN PTPN13 25348397 N/A physical interaction ComPPI
PTEN AATK 25348397 N/A physical interaction ComPPI
PTEN ERBB3 25348397 N/A physical interaction ComPPI
PTEN PTK7 25348397 N/A physical interaction ComPPI
PTEN DLC1 25348397 N/A physical interaction ComPPI
PTEN ITPR3 25348397 N/A physical interaction ComPPI
PTEN ECSCR 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
PTEN KIF11 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
PTEN TRMO 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PTEN CCDC180 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PTEN TMEFF1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PTEN UBA1 24234451 24656772 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
PTEN PHLPP2 21804599 24234451 25348397 physical association filter binding ComPPI,IntAct
PTEN HAVCR2 24234451 25348397 26492563 association anti bait coimmunoprecipitation ComPPI,IntAct
ARF4 PTEN 25348397 N/A physical interaction ComPPI
RPL23 PTEN 25348397 N/A physical interaction ComPPI
RPL14 PTEN 25348397 N/A physical interaction ComPPI
EEF1A2 PTEN 25348397 N/A physical interaction ComPPI
PELO PTEN 25348397 N/A physical interaction ComPPI
PTEN PTEN 24234451 24766807 physical association anti tag coimmunoprecipitation,bioluminescence resonance energy transfer,pull down,comigration in non denaturing gel electrophoresis IntAct
PTEN MAGI1 15629897 15951562 27898060 N/A N/A OmniPath
SRC PTEN 12869565 21532586 23995781 25829446 27898060 inhibition N/A OmniPath
LCK PTEN 10866658 11948419 12077256 12297295 27898060 stimulant N/A OmniPath
CTNNB1 PTEN 16219695 20123964 27898060 N/A N/A OmniPath
PTEN CTNNB1 16219695 20123964 27898060 N/A N/A OmniPath
PTEN PDGFRB 14718524 16456542 25241761 27898060 N/A N/A OmniPath
PTEN CREB1 21385900 27898060 N/A N/A OmniPath
EGR1 PTEN 12384981 27898060 stimulant N/A OmniPath
ROCK1 PTEN 12297295 15793569 27898060 stimulant N/A OmniPath
STK11 PTEN 10866658 15987703 18321849 21779440 27898060 inhibition N/A OmniPath
PLK3 PTEN 12297295 16107342 19629644 20940307 24047694 27898060 inhibition N/A OmniPath
PTEN STAT5A 20596030 27898060 inhibition N/A OmniPath
PTEN PDPK1 11943559 27898060 stimulant N/A OmniPath
ATM PTEN 23888040 25701194 27898060 N/A N/A OmniPath
AKT1 PTEN 10866658 12077256 12297295 19903340 20596030 27898060 N/A N/A OmniPath
PTEN AKT1 10866658 12040186 12077256 12297295 14585353 15184909 15534002 16288286 19903340 20596030 27898060 9779982 inhibition N/A OmniPath
PTEN PPM1A 18482992 27898060 stimulant N/A OmniPath
PTEN PTK2 10400703 10427092 11857088 15717329 23397142 27898060 9616126 inhibition N/A OmniPath
NEDD4 PTEN 17218260 18498243 19345329 21986318 24063548 24141722 25547115 27898060 inhibition,stimulant N/A OmniPath
PTEN RAC1 10753747 27898060 stimulant N/A OmniPath
TP53 PTEN 12620407 14559824 18431400 24141722 27898060 stimulant N/A OmniPath
PTEN SHC1 10427092 21206972 27898060 inhibition N/A OmniPath
PTEN E2F1 17218262 27898060 stimulant N/A OmniPath
PIK3C3 PTEN 20212113 27898060 stimulant N/A OmniPath
PTEN SP1 12804776 27898060 inhibition N/A OmniPath
PPP1CA PTEN 17274640 27898060 N/A N/A OmniPath
RELA PTEN 14729949 27898060 inhibition N/A OmniPath
PTEN AKT3 10644997 27898060 inhibition,stimulant N/A OmniPath
CSNK2A1 PTEN 10866658 11035045 11431330 12077256 12297295 12869565 14976311 15717329 16107342 16690621 17240336 17565999 18321849 21779440 22413754 24706748 24766807 25823029 26411369 27898060 inhibition N/A OmniPath
PPARG PTEN 23128507 27898060 inhibition N/A OmniPath
CDC42 PTEN 16381926 27898060 stimulant N/A OmniPath
PTEN AKT2 10970827 27898060 inhibition N/A OmniPath
PREX2 PTEN 19729658 27898060 inhibition N/A OmniPath
GSK3B PTEN 16107342 27898060 inhibition N/A OmniPath
PTEN PIK3CB 18794881 27898060 inhibition N/A OmniPath
FGFR3 PTEN 11948419 19345329 22891331 27898060 N/A N/A OmniPath
CSNK2A2 PTEN 12297295 27898060 N/A N/A OmniPath
CDK19 PTEN 12077256 12297295 16107342 27898060 N/A N/A OmniPath
MAST1 PTEN 15951562 27898060 inhibition N/A OmniPath
MAST2 PTEN 10646847 15951562 27898060 stimulant N/A OmniPath
MAST3 PTEN 15951562 27898060 stimulant N/A OmniPath
FRK PTEN 19345329 27898060 N/A N/A OmniPath

Visualization










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