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GENE：NR1D1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NR1D1
FullNmae nuclear receptor subfamily 1 group D member 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7962
EnsembleID ENSG00000126368
Uniprot P20393

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NR1D1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NR1D1 GO:0000122,GO:0000122,GO:0000122,GO:0000785,GO:0000785,GO:0000976,GO:0000977,GO:0000978,GO:0000978,GO:0000978,GO:0000981,GO:0001222,GO:0001222,GO:0001227,GO:0001678,GO:0003707,GO:0004879,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005978,GO:0008270,GO:0009755,GO:0010498,GO:0016604,GO:0019216,GO:0020037,GO:0030154,GO:0030425,GO:0030522,GO:0031648,GO:0032922,GO:0034144,GO:0042632,GO:0042749,GO:0042752,GO:0043124,GO:0043197,GO:0043401,GO:0044321,GO:0044321,GO:0045598,GO:0045892,GO:0045892,GO:0045893,GO:0045944,GO:0050728,GO:0060086,GO:0061178,GO:0061469,GO:0061889,GO:0070859,GO:0070888,GO:0071222,GO:0071347,GO:0071356,GO:0120163,GO:0150079,GO:1903979,GO:1990837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NR1D1 hsa:9572 path:hsa04710 Circadian rhythm - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP NR1D1 21832049 23180781 physical association protein array InnateDB
NR1D1 NR2E3 15190009 23331499 stimulation N/A SignaLink
NR2E3 NR1D1 15190009 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR NR1D1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 NR1D1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 NR1D1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC NR1D1 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
RORA NR1D1 12377782 22024429 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
FOXP3 NR1D1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 NR1D1 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 NR1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NR1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NR1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NR1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NR1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NR1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NR1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PPARG NR1D1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 NR1D1 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
GSK3B NR1D1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
TDO2 NR1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HDAC3 NR1D1 20534529 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NCOR2 NR1D1 25348397 N/A two hybrid,physical interaction,in vitro ComPPI
NCOR1 NR1D1 14525934 15604093 20581824 24234451 25348397 27898060 8948627 9482666 physical association two hybrid,experimental interaction detection,fluorescent resonance energy transfer,x-ray crystallography,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
UBB NR1D1 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
UBC NR1D1 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
RPS27A NR1D1 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
UBA52 NR1D1 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
APOA4 NR1D1 24234451 24311788 25348397 27898060 colocalization,physical association anti tag coimmunoprecipitation,confocal microscopy,proximity ligation assay ComPPI,IntAct,OmniPath
PKM NR1D1 25348397 N/A protein kinase assay ComPPI
NR2E3 NR1D1 14525934 15190009 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
HUWE1 NR1D1 20534529 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPG21 NR1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MYCBP2 NR1D1 20534529 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
C1D NR1D1 25348397 N/A physical interaction ComPPI
NR1D1 APP 25348397 N/A physical interaction ComPPI
NR1D1 INPP1 25348397 N/A physical interaction ComPPI
NR1D1 NR1D2 14525934 15604093 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
NR1D1 NR1D1 11669620 14525934 9660968 N/A experimental interaction detection HPRD
NR1D1 ARNTL 18662546 20159955 25260595 27898060 inhibition N/A OmniPath
GSK3B NR1D1 16484495 27898060 stimulant N/A OmniPath
NR2E3 NR1D1 15190009 27898060 stimulant N/A OmniPath
C1D NR1D1 27898060 9405624 stimulant N/A OmniPath

Visualization










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