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GENE：NR1D2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NR1D2
FullNmae nuclear receptor subfamily 1 group D member 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7963
EnsembleID ENSG00000174738
Uniprot Q14995

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NR1D2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NR1D2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NR1D2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NR1D2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NR1D2 GO:0000122,GO:0000785,GO:0000978,GO:0000978,GO:0000981,GO:0001227,GO:0004879,GO:0004879,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0006355,GO:0008270,GO:0009755,GO:0019216,GO:0030154,GO:0030522,GO:0042752,GO:0045892,GO:0045893,GO:0045944,GO:0048512,GO:0050727,GO:0050728,GO:0055088,GO:0097009,GO:1990837,GO:2001014

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NR1D2 hsa:9975 path:hsa04710 Circadian rhythm - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR NR1D2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 NR1D2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 NR1D2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 NR1D2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 NR1D2 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 NR1D2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 NR1D2 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 NR1D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NR1D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NR1D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NR1D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 NR1D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NR1D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NR1D2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001F0C23 NR1D2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000028BB8 NR1D2 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS000016D2D4 NR1D2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000EC1BE NR1D2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001B341F NR1D2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 NR1D2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 NR1D2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002AB575 NR1D2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004F4657 NR1D2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC NR1D2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000058878F NR1D2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 NR1D2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 NR1D2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C NR1D2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 NR1D2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 NR1D2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 NR1D2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE NR1D2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000321A1A NR1D2 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RBPMS NR1D2 25348397 N/A physical interaction ComPPI
BHLHE40 NR1D2 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
KRTAP4-2 NR1D2 25348397 N/A physical interaction ComPPI
GTF2B NR1D2 25348397 N/A physical interaction ComPPI
KRT40 NR1D2 25348397 N/A physical interaction ComPPI
NCOR1 NR1D2 14525934 25348397 8948627 9482666 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CSNK1E NR1D2 25348397 N/A physical interaction ComPPI
CSNK2A2 NR1D2 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TAF6 NR1D2 25348397 N/A physical interaction ComPPI
MID2 NR1D2 25348397 N/A physical interaction ComPPI
SIN3B NR1D2 25348397 N/A physical interaction ComPPI
TRIM25 NR1D2 25348397 N/A physical interaction ComPPI
NR1D1 NR1D2 14525934 15604093 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
TRIM27 NR1D2 25348397 N/A physical interaction ComPPI
CLOCK NR1D2 25348397 N/A physical interaction ComPPI
CRY1 NR1D2 25348397 N/A physical interaction ComPPI
SATB2 NR1D2 25348397 N/A physical interaction ComPPI
KAT5 NR1D2 25348397 N/A physical interaction ComPPI
RORC NR1D2 23555304 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRMT6 NR1D2 23455924 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
HDAC1 NR1D2 25348397 N/A physical interaction ComPPI
NR1D2 KRTAP10-9 25348397 N/A physical interaction ComPPI
NCOA5 NR1D2 11113208 14525934 N/A experimental interaction detection,two hybrid HPRD
NR1D2 CUL1 14525934 15604093 N/A two hybrid HPRD
NR1D2 UBE2I 14525934 15604093 N/A two hybrid HPRD
NR1D2 ARNTL 18662546 27898060 inhibition N/A OmniPath

Visualization










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