GENE:AQP3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | AQP3 |
| FullNmae | aquaporin 3 (Gill blood group) |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:636 |
| EnsembleID | ENSG00000165272 |
| Uniprot | Q92482 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| AQP3 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| AQP3 | GO:0002684,GO:0003091,GO:0005515,GO:0005654,GO:0005737,GO:0005886,GO:0005886,GO:0005886,GO:0005911,GO:0006833,GO:0006833,GO:0006833,GO:0015204,GO:0015250,GO:0015250,GO:0015250,GO:0015250,GO:0015254,GO:0015254,GO:0015793,GO:0015793,GO:0016020,GO:0016323,GO:0016323,GO:0032526,GO:0033280,GO:0042476,GO:0042802,GO:0045616,GO:0051592,GO:0051649,GO:0070295,GO:0071456,GO:0071918,GO:0090650 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| AQP3 | hsa:360 | path:hsa04962 | Vasopressin-regulated water reabsorption - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | AQP3 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR2 | AQP3 | 20034404 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | AQP3 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | AQP3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| MYC | AQP3 | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| YBX1 | AQP3 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | AQP3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | AQP3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | AQP3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | AQP3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | AQP3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | AQP3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | AQP3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CREB1 | AQP3 | 18495115 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | AQP3 | 11231003 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP73 | AQP3 | 11231003 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ATF1 | AQP3 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00003D5391 | AQP3 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000036AFF1 | AQP3 | 23800944 24462679 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay | TarBase |
| URS00002367FA | AQP3 | 24070899 25416803 | mrna cleavage,inhibition | western blot,miRNA interference luciferase reporter assay | TarBase |
| URS00004900F1 | AQP3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | AQP3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AA845 | AQP3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075BDA4 | AQP3 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000061E50F | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000070B1D | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000045B99E | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003A5E54 | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FB065 | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001310DE | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000081D1E | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000427B68 | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003A8BB2 | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000080D0A | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008AA34 | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C02E4 | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039A25B | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075B13F | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AEA5 | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004283FE | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000118224 | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000037B2E0 | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000319E1 | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000496C56 | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000012930C | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD02D | AQP3 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LMNA | AQP3 | 25348397 | N/A | physical interaction | ComPPI |
| OLFM4 | AQP3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| PLD2 | AQP3 | 14525934 14675200 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| CAV1 | AQP3 | 25348397 | N/A | physical interaction | ComPPI |
| TNF | AQP3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| STX1A | AQP3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| PLP2 | AQP3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ELAVL1 | AQP3 | 25348397 | N/A | physical interaction | ComPPI |
| CD79A | AQP3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AQP3 | SAR1A | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AQP3 | ERGIC3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AQP3 | GPX8 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AQP3 | MRM1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AQP3 | GPR152 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AQP3 | SGPL1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AQP3 | FAM209A | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AQP3 | SSMEM1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AQP3 | HIBADH | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AQP3 | TMEM107 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AQP3 | LEUTX | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
