GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
AQP5 |
FullNmae |
aquaporin 5 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:638 |
EnsembleID |
ENSG00000161798 |
Uniprot |
P55064 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
AQP5 |
ferroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
AQP5 |
GO:0005515,GO:0005783,GO:0005886,GO:0005886,GO:0005886,GO:0005902,GO:0006833,GO:0006833,GO:0009925,GO:0015250,GO:0015250,GO:0015670,GO:0015670,GO:0016324,GO:0016324,GO:0030157,GO:0030659,GO:0042476,GO:0042802,GO:0046541,GO:0048593,GO:0051289,GO:0055085,GO:0070062,GO:0071476 |
KEGG Annotation:
GeneSymbol |
GeneID |
Pathway |
Pathway Name |
AQP5 |
hsa:362 |
path:hsa04970 |
Salivary secretion - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
AQP5 |
HNRNPK |
23180781
25416956
|
physical association |
two hybrid |
InnateDB |
AQP5 |
KRT31 |
23180781
25416956
|
physical association |
two hybrid |
InnateDB |
AQP5 |
KRT40 |
23180781
25416956
|
physical association |
two hybrid |
InnateDB |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
YBX1 |
AQP5 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
EGR1 |
AQP5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
AQP5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
AQP5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS0000237AF9 |
AQP5 |
18185580
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
PRKACA |
AQP5 |
22135298
|
phosphorylation |
N/A |
PhosphoSite |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
HNRNPK |
AQP5 |
24234451
25348397
25416956
|
physical association |
two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid |
ComPPI,IntAct |
AQP5 |
KRT31 |
24234451
25348397
25416956
|
physical association |
two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid |
ComPPI,IntAct |
AQP5 |
KRT40 |
24234451
25348397
25416956
|
physical association |
two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid |
ComPPI,IntAct |
AQP5 |
MDFI |
14525934
16189514
19060904
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid |
ComPPI,HPRD,IntAct |
AQP5 |
GLRX |
21988832
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
AQP5 |
WNT2 |
21988832
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
AQP5 |
NOTCH2NLA |
24234451
25348397
25416956
|
physical association |
physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid |
ComPPI,IntAct |
AQP5 |
CREB3 |
21516116
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
AQP5 |
AQP5 |
18768791
24234451
|
N/A |
molecular sieving,x-ray crystallography |
IntAct |
AQP5 |
TRPV4 |
16571723
27898060
|
N/A |
N/A |
OmniPath |
PRKACA |
AQP5 |
18478076
26569106
27898060
|
N/A |
N/A |
OmniPath |
Visualization