GENE：AQP8
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | AQP8 |
| FullNmae | aquaporin 8 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:642 |
| EnsembleID | ENSG00000103375 |
| Uniprot | O94778 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| AQP8 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| AQP8 | GO:0005515,GO:0005739,GO:0005743,GO:0005743,GO:0005790,GO:0005886,GO:0005886,GO:0005886,GO:0006833,GO:0006833,GO:0006833,GO:0008519,GO:0015250,GO:0015250,GO:0015250,GO:0015250,GO:0015264,GO:0015265,GO:0015840,GO:0015843,GO:0016323,GO:0016324,GO:0030183,GO:0030868,GO:0031526,GO:0031966,GO:0035377,GO:0045177,GO:0045540,GO:0046691,GO:0046691,GO:0071320,GO:0071918,GO:0072488,GO:0072488,GO:0072489,GO:0080170,GO:0080170,GO:0097708,GO:0140157,GO:1990748 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| AQP8 | hsa:343 | path:hsa04976 | Bile secretion - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GATA1 | AQP8 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | AQP8 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| CEBPA | AQP8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | AQP8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | AQP8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | AQP8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SERP1 | AQP8 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| PLP2 | AQP8 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |