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GENE：INTS2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol INTS2
FullNmae integrator complex subunit 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:29241
EnsembleID ENSG00000108506
Uniprot Q9H0H0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
INTS2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
INTS2 GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0016020,GO:0016180,GO:0016180,GO:0031965,GO:0032039,GO:0032039,GO:0032039,GO:0034243,GO:0034472

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
INTS2 CREB1 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 INTS2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 INTS2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 INTS2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 INTS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A INTS2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001799A3 INTS2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 INTS2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000007F792 INTS2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000122F23 INTS2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000015D23B INTS2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C0D3F INTS2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C INTS2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000498DAA INTS2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000042619A INTS2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000009265 INTS2 23824327 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS000058863C INTS2 23824327 25416803 28735896 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
POLR2C INTS2 25361965 interaction type N/A PTMCode2
INTS2 POLR2C 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NCK2 INTS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DEF6 INTS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP2R1A INTS2 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
DPEP1 INTS2 25348397 N/A physical interaction ComPPI
SLAMF1 INTS2 25348397 N/A physical interaction ComPPI
PPP2CB INTS2 25348397 N/A physical interaction ComPPI
HNRNPL INTS2 25348397 N/A physical interaction ComPPI
PPP2CA INTS2 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
SUV39H1 INTS2 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SOX2 INTS2 25348397 N/A physical interaction ComPPI
CD70 INTS2 25348397 N/A physical interaction ComPPI
ATP6V1B1 INTS2 25348397 N/A physical interaction ComPPI
APLNR INTS2 25348397 N/A physical interaction ComPPI
SEM1 INTS2 25348397 N/A physical interaction ComPPI
CD274 INTS2 25348397 N/A physical interaction ComPPI
KDM1A INTS2 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CKAP5 INTS2 25348397 N/A physical interaction ComPPI
TGOLN2 INTS2 25348397 N/A physical interaction ComPPI
FAS INTS2 25348397 N/A physical interaction ComPPI
RPP30 INTS2 25348397 N/A physical interaction ComPPI
POLR2C INTS2 18562274 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
INTS11 INTS2 25348397 N/A physical interaction ComPPI
INTS13 INTS2 25348397 N/A physical interaction ComPPI
ABCF3 INTS2 25348397 N/A physical interaction ComPPI
INTS1 INTS2 25348397 N/A physical interaction ComPPI
C7ORF26 INTS2 25348397 N/A physical interaction ComPPI
INTS10 INTS2 25348397 N/A physical interaction ComPPI
SNX4 INTS2 25348397 N/A physical interaction ComPPI
SEM1 INTS2 25348397 N/A physical interaction ComPPI
DKKL1 INTS2 25348397 N/A physical interaction ComPPI
INTS7 INTS2 25348397 N/A physical interaction ComPPI
INTS3 INTS2 25348397 N/A physical interaction ComPPI
INTS2 INTS5 25348397 N/A physical interaction ComPPI
INTS2 INTS6 25348397 N/A physical interaction ComPPI
INTS2 INTS8 25348397 N/A physical interaction ComPPI
INTS2 SCN2B 25348397 N/A physical interaction ComPPI
INTS2 INTS14 25348397 N/A physical interaction ComPPI
INTS2 VSIG1 25348397 N/A physical interaction ComPPI
INTS2 FAM174A 25348397 N/A physical interaction ComPPI
INTS2 SLC15A1 25348397 N/A physical interaction ComPPI
INTS2 STING1 24234451 25348397 29251827 association anti bait coimmunoprecipitation ComPPI,IntAct
ATP6V1B2 INTS2 25348397 N/A physical interaction ComPPI

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