GENE：MLLT1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | MLLT1 |
| FullNmae | MLLT1 super elongation complex subunit |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:7134 |
| EnsembleID | ENSG00000130382 |
| Uniprot | Q03111 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| MLLT1 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| MLLT1 | GO:0001650,GO:0003682,GO:0005515,GO:0005654,GO:0005654,GO:0005829,GO:0008023,GO:0008023,GO:0045893,GO:0070577 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| MLLT1 | hsa:4298 | path:hsa03250 | Viral life cycle - HIV-1 - Homo sapiens (human) |
| MLLT1 | hsa:4298 | path:hsa05202 | Transcriptional misregulation in cancer - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | MLLT1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | MLLT1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | MLLT1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | MLLT1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | MLLT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | MLLT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | MLLT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | MLLT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | MLLT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | MLLT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | MLLT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | MLLT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | MLLT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | MLLT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | MLLT1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000324096 | MLLT1 | N/A | rna interference,inhibition | experimental interaction detection | miRSponge |
| URS0000324096 | MLLT1 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection,experimental interaction detection,experimental interaction detection | TarBase |
| URS00005651EE | MLLT1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001BCAC5 | MLLT1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000424278 | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002394F5 | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000547F6A | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D15B | MLLT1 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000077DDE | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C403E | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000035D2F9 | MLLT1 | 23592263 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00005485E8 | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000913AC | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000037D7E5 | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003883FE | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039E1E1 | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DDD35 | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000042E1F | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000298BA3 | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002075FA | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B3783 | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000600E6 | MLLT1 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | MLLT1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | MLLT1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | MLLT1 | 20371350 23313552 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000048D44E | MLLT1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005CCD18 | MLLT1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AB32B | MLLT1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008B558 | MLLT1 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000236310 | MLLT1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000060AABB | MLLT1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000017EA6A | MLLT1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000022AAA | MLLT1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004DEA91 | MLLT1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005FDCD1 | MLLT1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000393C7 | MLLT1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000044FD7 | MLLT1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002578DA | MLLT1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000016914 | MLLT1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003A5E54 | MLLT1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D2680 | MLLT1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004283FE | MLLT1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000059EB31 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000366551 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000019907A | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000137EDE | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000148B91 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EED18 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000027352D | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C7B2B | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D1FC | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AD450 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000005E58C | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001F5B39 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00003758F0 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002198F3 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000247AC6 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C0099 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00005F9738 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CE046 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000334286 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001ADE63 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000003575B | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AE8D3 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E728C | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000041FA2C | MLLT1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ATM | MLLT1 | 22135298 | phosphorylation | N/A | PhosphoSite |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CDC73 | MLLT1 | 20541477 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| CBX8 | MLLT1 | 11313972 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| SKP1 | MLLT1 | 20203130 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| BMI1 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| RYBP | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| H4C1 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| CSNK2A1 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| AFF1 | MLLT1 | 14525934 15856011 20153263 24234451 25348397 | association | affinity chromatography technology,anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,IntAct |
| H2BC21 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| RPL12 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| ARRB2 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| EPB41L2 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| H3-4 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| H1-5 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| RNF2 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| POLR2A | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| CCNT1 | MLLT1 | 20153263 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| ELL | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| SIRT1 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| MED26 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| H3C1 | MLLT1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| BCOR | MLLT1 | 24234451 25348397 27505670 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| CDK9 | MLLT1 | 20153263 21729782 23455922 23602568 24234451 25348397 | association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification | ComPPI,IntAct |
| RFX5 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| YAF2 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| MLLT10 | MLLT1 | 14525934 15856011 20203130 24234451 25348397 | association | anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| EAF1 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| H2AX | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| CHD1 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| ESR2 | MLLT1 | 21182203 24234451 25348397 | association | cosedimentation through density gradient | ComPPI,IntAct |
| BRD4 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| RFXAP | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| MLLT6 | MLLT1 | 20203130 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| AFF4 | MLLT1 | 14525934 15856011 20153263 21729782 24234451 25348397 | association,physical association | affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| ARID1A | MLLT1 | 12665591 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| MLLT1 | DOT1L | 20153263 20203130 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MLLT1 | MLLT3 | 20203130 21729782 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MLLT1 | ACACA | 25348397 | N/A | physical interaction | ComPPI |
| MLLT1 | KMT2A | 25348397 | N/A | physical interaction | ComPPI |
| MLLT1 | ELL2 | 21729782 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MLLT1 | PAF1 | 25348397 | N/A | physical interaction | ComPPI |
| MLLT1 | ELL3 | 25348397 | N/A | physical interaction | ComPPI |
| MLLT1 | SLC25A10 | 25348397 | N/A | physical interaction | ComPPI |
| MLLT1 | H2AC20 | 25348397 | N/A | physical interaction | ComPPI |
| MLLT1 | PIP4K2A | 25348397 | N/A | physical interaction | ComPPI |
| MLLT1 | CAMKV | 25348397 | N/A | physical interaction | ComPPI |
| MLLT1 | BPIFB1 | 25348397 | N/A | physical interaction | ComPPI |
| MLLT1 | DENND2D | 25348397 | N/A | physical interaction | ComPPI |
| MLLT1 | ALKBH4 | 23145062 24234451 25348397 | colocalization,physical association | two hybrid,physical interaction,confocal microscopy | ComPPI,IntAct |
| MLLT1 | YIF1A | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MLLT1 | PCGF1 | 24234451 25348397 27505670 | association | tandem affinity purification | ComPPI,IntAct |
| WDR5 | MLLT1 | 18829457 18829459 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| MRPL12 | MLLT1 | 25348397 | N/A | physical interaction | ComPPI |
| YARS2 | MLLT1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| ATM | MLLT1 | 25921070 27898060 | N/A | N/A | OmniPath |