Gene Information gene info

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GENE：RBX1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RBX1
FullNmae ring-box 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9928
EnsembleID ENSG00000100387
Uniprot P62877

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RBX1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RBX1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RBX1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RBX1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RBX1 GO:0000165,GO:0000209,GO:0004842,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0006281,GO:0006511,GO:0006511,GO:0006513,GO:0006974,GO:0006974,GO:0007283,GO:0008270,GO:0016567,GO:0016567,GO:0016567,GO:0019005,GO:0019005,GO:0019788,GO:0031146,GO:0031146,GO:0031461,GO:0031461,GO:0031462,GO:0031463,GO:0031464,GO:0031464,GO:0031465,GO:0031466,GO:0031467,GO:0031625,GO:0032436,GO:0032480,GO:0034450,GO:0034644,GO:0034644,GO:0042110,GO:0043123,GO:0043161,GO:0043161,GO:0043687,GO:0045116,GO:0045732,GO:0060090,GO:0061629,GO:0061630,GO:0061630,GO:0061630,GO:0061663,GO:0062197,GO:0070936,GO:0071230,GO:0090090,GO:0097602,GO:0097602,GO:0097602,GO:0140627,GO:1902499,GO:1904263

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RBX1 hsa:9978 path:hsa03420 Nucleotide excision repair - Homo sapiens (human)
RBX1 hsa:9978 path:hsa04066 HIF-1 signaling pathway - Homo sapiens (human)
RBX1 hsa:9978 path:hsa04110 Cell cycle - Homo sapiens (human)
RBX1 hsa:9978 path:hsa04114 Oocyte meiosis - Homo sapiens (human)
RBX1 hsa:9978 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)
RBX1 hsa:9978 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)
RBX1 hsa:9978 path:hsa04310 Wnt signaling pathway - Homo sapiens (human)
RBX1 hsa:9978 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)
RBX1 hsa:9978 path:hsa04710 Circadian rhythm - Homo sapiens (human)
RBX1 hsa:9978 path:hsa05131 Shigellosis - Homo sapiens (human)
RBX1 hsa:9978 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
RBX1 hsa:9978 path:hsa05200 Pathways in cancer - Homo sapiens (human)
RBX1 hsa:9978 path:hsa05211 Renal cell carcinoma - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RBX1 CUL1 10023660 10230406 10230407 10535940 10648623 10671552 10713156 11348595 11861641 11900249 11955436 11956208 11961546 11967263 12051714 12417738 12609982 12648680 12706828 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16759355 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 18988627 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 19933270 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21071413 21411632 22270359 22682247 22730322 23180781 23331499 23343194 23732914 24023259 25730849 26159692 26192618 26885856 7542250 7641885 8666229 9694792 interaction type,stimulation,physical association anti tag coimmunoprecipitation ACSN,InnateDB,SignaLink,SignaLink
RBX1 SKP1 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 SKP2 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 DDB1 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398 26192618 interaction type N/A ACSN
RBX1 CUL2 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 RACK1 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 VHL 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15601820 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258 23180781 26192618 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
RBX1 CUL3 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 26192618 27984721 9242610 interaction type N/A ACSN
RBX1 KEAP1 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759 26192618 interaction type N/A ACSN
RBX1 CISH 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17884153 18420585 18931676 19622404 19622774 19686080 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 CUL4A 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143 26192618 interaction type N/A ACSN
RBX1 TSC2 11900249 12648680 12820959 12906785 15340381 15459660 15688063 15703371 16636147 16697054 17680028 17884153 18381890 18931676 19022819 19440234 19622404 19686080 19809470 19847258 20146692 20211143 26192618 interaction type N/A ACSN
RBX1 RICTOR 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16469695 16697054 17884153 18931676 19143635 19622404 19686080 19809470 19847258 20832730 26159692 26192618 interaction type N/A ACSN
APC RBX1 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26192618 26885856 7542250 7641885 8666229 9694792 interaction type N/A ACSN
RBX1 AMER1 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26192618 26885856 7542250 7641885 8666229 9694792 interaction type N/A ACSN
RBX1 CSN2 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26192618 26885856 7542250 7641885 8666229 9694792 interaction type N/A ACSN
RBX1 CSN3 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26192618 26885856 7542250 7641885 8666229 9694792 interaction type N/A ACSN
RBX1 NEDD8 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26192618 26885856 7542250 7641885 8666229 9694792 interaction type N/A ACSN
RBX1 USP15 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26192618 26885856 7542250 7641885 8666229 9694792 interaction type N/A ACSN
CAND1 RBX1 12504025 12504026 15537541 26192618 interaction type N/A ACSN
RBX1 FANCM 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 CDC25A 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 WEE1 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 HIF1A 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
OS9 RBX1 12351678 15652751 15721254 26192618 interaction type N/A ACSN
RBX1 NFE2L2 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759 26192618 interaction type N/A ACSN
RBX1 BCL2L11 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17884153 18420585 18931676 19622404 19622774 19686080 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 DDIT4 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143 26192618 interaction type N/A ACSN
RBX1 NFKBIA 10066435 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19150432 19270156 19622404 19686080 19809470 19847258 26192618 9859996 interaction type N/A ACSN
RBX1 BCL2 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759 26192618 interaction type N/A ACSN
TNFAIP3 RBX1 20599425 26192618 interaction type N/A ACSN
SQSTM1 RBX1 14744430 15340068 16252010 18545270 19427028 20531300 21981924 25002027 26192618 26587781 28574505 interaction type N/A ACSN
RBX1 PDCD4 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16697054 17053147 17884153 18931676 19270156 19622404 19686080 19797085 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 MTOR 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18636226 18787170 18931676 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 SGK1 11154281 11500365 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16469695 16697054 17884153 18570873 18636226 18925875 18931676 19143635 19584721 19622404 19686080 19809470 19847258 20338997 20832730 26159692 26192618 interaction type N/A ACSN
AKT1 RBX1 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 26192618 27331412 28216025 9812896 interaction type N/A ACSN
RBX1 PPP3CB 11900249 12648680 12820959 15071497 15340381 15459660 15489953 15688063 15703371 16697054 17884153 18931676 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 SUFU 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16611981 16697054 17884153 18931676 19150432 19270156 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
RBX1 ULK3 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16611981 16697054 17884153 18931676 19150432 19270156 19622404 19686080 19809470 19847258 26192618 interaction type N/A ACSN
LRR1 RBX1 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
RBX1 FEM1B 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
FBXO31 RBX1 16357137 23180781 physical association anti tag coimmunoprecipitation InnateDB
RBX1 CASP3 17217622 23180781 physical association anti tag coimmunoprecipitation InnateDB
RBX1 CUL7 12904573 23180781 physical association anti tag coimmunoprecipitation InnateDB
CUL1 RBX1 10648623 11956208 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
RBX1 FBXO2 18203720 23180781 physical association anti tag coimmunoprecipitation InnateDB
FBXO6 RBX1 18203720 23180781 physical association anti tag coimmunoprecipitation InnateDB
FBXO44 RBX1 18203720 23180781 physical association anti tag coimmunoprecipitation InnateDB
FBXO27 RBX1 18203720 23180781 physical association anti tag coimmunoprecipitation InnateDB
SARS2 RBX1 18203720 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR RBX1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 RBX1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 RBX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RBX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RBX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RBX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RBX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AF45F RBX1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 RBX1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 RBX1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000036B845 RBX1 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RBX1 CDKN1B 25361965 interaction type N/A PTMCode2
CDKN1B RBX1 25361965 interaction type N/A PTMCode2
RBX1 SKP1 25361965 interaction type N/A PTMCode2
SKP1 RBX1 25361965 interaction type N/A PTMCode2
RBX1 NEDD8 25361965 interaction type N/A PTMCode2
NEDD8 RBX1 25361965 interaction type N/A PTMCode2
RBX1 UBE2M 25361965 interaction type N/A PTMCode2
UBE2M RBX1 25361965 interaction type N/A PTMCode2
RBX1 VHL 25361965 interaction type N/A PTMCode2
VHL RBX1 25361965 interaction type N/A PTMCode2
RBX1 DDB2 25361965 interaction type N/A PTMCode2
DDB2 RBX1 25361965 interaction type N/A PTMCode2
RBX1 CUL3 25361965 interaction type N/A PTMCode2
CUL3 RBX1 25361965 interaction type N/A PTMCode2
RBX1 SKP2 25361965 interaction type N/A PTMCode2
SKP2 RBX1 25361965 interaction type N/A PTMCode2
RBX1 FBXW7 25361965 interaction type N/A PTMCode2
FBXW7 RBX1 25361965 interaction type N/A PTMCode2
RBX1 CAND1 25361965 interaction type N/A PTMCode2
CAND1 RBX1 25361965 interaction type N/A PTMCode2
RBX1 CUL5 25361965 interaction type N/A PTMCode2
CUL5 RBX1 25361965 interaction type N/A PTMCode2
RBX1 DDB1 25361965 interaction type N/A PTMCode2
DDB1 RBX1 25361965 interaction type N/A PTMCode2
RBX1 COPS6 25361965 interaction type N/A PTMCode2
COPS6 RBX1 25361965 interaction type N/A PTMCode2
RBX1 FEM1B 25361965 interaction type N/A PTMCode2
FEM1B RBX1 25361965 interaction type N/A PTMCode2
RBX1 FBXW8 25361965 interaction type N/A PTMCode2
FBXW8 RBX1 25361965 interaction type N/A PTMCode2
RBX1 FBXO31 25361965 interaction type N/A PTMCode2
FBXO31 RBX1 25361965 interaction type N/A PTMCode2
RBX1 CUL1 25361965 interaction type N/A PTMCode2
CUL1 RBX1 25361965 interaction type N/A PTMCode2
RBX1 CUL4A 25361965 interaction type N/A PTMCode2
CUL4A RBX1 25361965 interaction type N/A PTMCode2
RBX1 CUL4B 25361965 interaction type N/A PTMCode2
CUL4B RBX1 25361965 interaction type N/A PTMCode2
CDC34 RBX1 25361965 interaction type N/A PTMCode2
RBX1 CDC34 25361965 interaction type N/A PTMCode2
KEAP1 RBX1 25361965 interaction type N/A PTMCode2
RBX1 KEAP1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CUL5 RBX1 14525934 14564014 18805092 24234451 25348397 neddylation reaction,physical association experimental interaction detection,x-ray crystallography,physical interaction,enzymatic study,in vivo ComPPI,HPRD,IntAct
HSPA8 RBX1 25348397 N/A physical interaction ComPPI
RHOBTB3 RBX1 25348397 N/A physical interaction ComPPI
PBX4 RBX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTG1 RBX1 25348397 N/A physical interaction ComPPI
CCND1 RBX1 11311237 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
KRTAP12-2 RBX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDKN1B RBX1 18805092 24234451 25348397 ubiquitination reaction physical interaction,enzymatic study ComPPI,IntAct
SKP1 RBX1 10531037 11961546 12481031 12813041 14525934 24234451 25348397 27705803 association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
FBXO17 RBX1 25348397 N/A physical interaction ComPPI
FBXO2 RBX1 25348397 N/A physical interaction ComPPI
UBE2D1 RBX1 25348397 N/A physical interaction ComPPI
DCUN1D1 RBX1 25348397 N/A physical interaction ComPPI
KEAP1 RBX1 25348397 N/A physical interaction ComPPI
MED8 RBX1 12149480 24234451 25348397 association coimmunoprecipitation,physical interaction ComPPI,IntAct
KBTBD7 RBX1 25348397 N/A physical interaction ComPPI
UBE2R2 RBX1 25348397 N/A physical interaction ComPPI
UBE2E2 RBX1 25348397 N/A physical interaction ComPPI
UBE2E3 RBX1 25348397 N/A physical interaction ComPPI
MAGEC2 RBX1 25348397 N/A physical interaction ComPPI
SERTAD1 RBX1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
H4C1 RBX1 25348397 N/A physical interaction ComPPI
ERBIN RBX1 25348397 N/A physical interaction ComPPI
EZH2 RBX1 23238014 24234451 25348397 26496610 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXW7 RBX1 25348397 N/A physical interaction ComPPI
CASP3 RBX1 25348397 N/A physical interaction ComPPI
MAP4K1 RBX1 25348397 N/A physical interaction ComPPI
SMAD3 RBX1 11359933 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
HIF1A RBX1 25348397 N/A physical interaction ComPPI
COPS5 RBX1 18850735 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
COP1 RBX1 25348397 N/A physical interaction ComPPI
KLHL3 RBX1 25348397 N/A physical interaction ComPPI
UBE2G1 RBX1 25348397 N/A physical interaction ComPPI
UBE2D2 RBX1 25348397 N/A physical interaction ComPPI
UBE2G2 RBX1 25348397 N/A physical interaction ComPPI
UBE2L3 RBX1 25348397 N/A physical interaction ComPPI
RHOB RBX1 25348397 N/A physical interaction ComPPI
RBX1 VHL 14525934 15601820 17353931 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
RBX1 CUL4B 12609982 14525934 23238014 24234451 25348397 26496610 association,physical association affinity chromatography technology,anti tag coimmunoprecipitation,experimental interaction detection,molecular sieving,physical interaction,in vitro ComPPI,HPRD,IntAct
RBX1 CUL1 11961546 12504026 12609982 14525934 18805092 20399188 21765416 22660580 24234451 24949976 25348397 ubiquitination reaction,neddylation reaction,association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,cosedimentation in solution,cross-linking study,experimental interaction detection,molecular sieving,pull down,x-ray crystallography,physical interaction,enzymatic study,in vitro,x ray scattering,ubiquitinase assay,neddylase assay ComPPI,HPRD,IntAct
RBX1 FBH1 11956208 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RBX1 CAND1 12504026 12609982 14525934 15537541 24234451 25348397 association,physical association affinity chromatography technology,anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,x-ray crystallography,physical interaction,in vitro ComPPI,HPRD,IntAct
RBX1 CUL3 11311237 14525934 25348397 N/A anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RBX1 CUL7 10531037 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
RBX1 GPS1 11337588 14525934 24234451 25348397 27029275 physical association transmission electron microscopy,experimental interaction detection,physical interaction,electron tomography,in vitro ComPPI,HPRD,IntAct
RBX1 FBXW8 10531037 12481031 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
RBX1 COPS6 11337588 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RBX1 CUL4A 14525934 18593899 22157821 24234451 25348397 association experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
RBX1 DET1 25348397 N/A physical interaction ComPPI
RBX1 CCND2 25348397 N/A physical interaction ComPPI
RBX1 CCND3 25348397 N/A physical interaction ComPPI
RBX1 CUL2 15601820 17183367 19327355 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RBX1 NEDD8 25348397 N/A physical interaction ComPPI
RBX1 FBXO3 25348397 N/A physical interaction ComPPI
RBX1 FBXO22 25348397 N/A physical interaction ComPPI
RBX1 TUBA1B 25348397 N/A physical interaction ComPPI
RBX1 HSPA1A 25348397 N/A physical interaction ComPPI
RBX1 HSPA1B 25348397 N/A physical interaction ComPPI
RBX1 SKP2 18239684 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 ABTB2 25348397 N/A physical interaction ComPPI
RBX1 RPS6KB1 25348397 N/A physical interaction ComPPI
RBX1 PTGS2 25348397 N/A physical interaction ComPPI
RBX1 FBXO11 17098746 22113614 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 PGAM5 25348397 N/A physical interaction ComPPI
RBX1 PSMA6 25348397 N/A physical interaction ComPPI
RBX1 DDB1 16473935 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 DDB2 16473935 24234451 25348397 26496610 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 FBXO31 25348397 N/A physical interaction ComPPI
RBX1 ZC3HC1 25348397 N/A physical interaction ComPPI
RBX1 GAN 25348397 N/A physical interaction ComPPI
RBX1 ENC1 25348397 N/A physical interaction ComPPI
RBX1 KLHL41 25348397 N/A physical interaction ComPPI
RBX1 DIO2 25348397 N/A physical interaction ComPPI
RBX1 ARID1B 25348397 N/A physical interaction ComPPI
RBX1 ELOB 12149480 24234451 25348397 association coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 FBXW11 25348397 N/A physical interaction ComPPI
RBX1 ING3 25348397 N/A physical interaction ComPPI
RBX1 DCAF1 25348397 N/A physical interaction ComPPI
RBX1 CORO7 21130766 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 UBXN7 18775313 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 TRPC4AP 25348397 N/A physical interaction ComPPI
RBX1 FBXO42 25348397 N/A physical interaction ComPPI
RBX1 CRBN 24234451 25348397 27029275 physical association transmission electron microscopy,physical interaction ComPPI,IntAct
RBX1 RICTOR 25348397 N/A physical interaction ComPPI
RBX1 MAPK8IP2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RBX1 MAP3K7 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RBX1 TAB1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RBX1 FRZB 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RBX1 MAP3K20 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RBX1 RAG1 25348397 N/A physical interaction ComPPI
RBX1 ELOC 12149480 24234451 25348397 association coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 HOXB4 25348397 N/A physical interaction ComPPI
RBX1 GLMN 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RBX1 ELAVL1 25348397 N/A physical interaction ComPPI
RBX1 MCM10 25348397 N/A physical interaction ComPPI
RBX1 PRAME 21822215 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 BTRC 25348397 N/A physical interaction ComPPI
RBX1 CUL9 25348397 N/A physical interaction ComPPI
RBX1 FBXW2 25348397 N/A physical interaction ComPPI
RBX1 FBXL5 25348397 N/A physical interaction ComPPI
RBX1 FBXO6 25348397 N/A physical interaction ComPPI
RBX1 FBXO44 25348397 N/A physical interaction ComPPI
RBX1 SARS2 25348397 N/A physical interaction ComPPI
RBX1 FBXO27 25348397 N/A physical interaction ComPPI
RBX1 PSMA2 25348397 N/A physical interaction ComPPI
RBX1 KLHL7 21828050 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 ERCC8 25348397 N/A physical interaction ComPPI
RBX1 FBXO25 25348397 N/A physical interaction ComPPI
RBX1 CCNF 25348397 N/A physical interaction ComPPI
RBX1 FBXL12 18660753 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
RBX1 PML 25348397 N/A physical interaction ComPPI
RBX1 HINT1 25348397 N/A physical interaction ComPPI
RBX1 GRK5 25348397 N/A physical interaction ComPPI
RBX1 MKNK2 25348397 N/A physical interaction ComPPI
RBX1 LRR1 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 LRRC14 25348397 N/A physical interaction ComPPI
RBX1 COPS3 25348397 N/A physical interaction ComPPI
RBX1 COPS4 25348397 N/A physical interaction ComPPI
RBX1 COPS7A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 UBE2D3 25348397 N/A physical interaction ComPPI
RBX1 UBE2M 19549727 21765416 24234451 25348397 physical association two hybrid,nuclear magnetic resonance,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RBX1 MYB 25348397 N/A physical interaction ComPPI
RBX1 APP 25348397 N/A physical interaction ComPPI
RBX1 SESN2 23274085 24234451 25348397 29294217 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 SESN1 25348397 N/A physical interaction ComPPI
RBX1 FEM1B 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 FBXL15 21572392 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 TRIM27 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RBX1 RNF126 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RBX1 TRIM74 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RBX1 HAX1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RBX1 OS9 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RBX1 GFPT1 25348397 N/A physical interaction ComPPI
RBX1 MTSS1 25348397 N/A physical interaction ComPPI
RBX1 VRK2 25348397 N/A physical interaction ComPPI
RBX1 NEDD4 25348397 N/A physical interaction ComPPI
RBX1 DCUN1D3 25348397 N/A physical interaction ComPPI
RBX1 DAB2IP 25348397 N/A physical interaction ComPPI
RBX1 TP53 22653443 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 UBE2L6 25348397 N/A physical interaction ComPPI
RBX1 ESR1 25348397 N/A physical interaction ComPPI
RBX1 IP6K1 25348397 N/A physical interaction ComPPI
RBX1 H1-1 25348397 N/A physical interaction ComPPI
RBX1 H1-2 25348397 N/A physical interaction ComPPI
RBX1 SAMHD1 25348397 N/A physical interaction ComPPI
RBX1 EEF1A1 25348397 N/A physical interaction ComPPI
RBX1 EEF1A1P5 25348397 N/A physical interaction ComPPI
RBX1 HSPB1 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
RBX1 KBTBD6 25348397 N/A physical interaction ComPPI
RBX1 FBXO21 25348397 N/A physical interaction ComPPI
RBX1 IBTK 25348397 N/A physical interaction ComPPI
RBX1 GATA2 25348397 N/A physical interaction ComPPI
RBX1 GHR 25348397 N/A physical interaction ComPPI
RBX1 KDM2B 25348397 N/A physical interaction ComPPI
RBX1 CREB3L3 25348397 N/A physical interaction ComPPI
RBX1 DCUN1D2 25348397 N/A physical interaction ComPPI
RBX1 DCUN1D4 25348397 N/A physical interaction ComPPI
RBX1 KCTD17 25348397 N/A physical interaction ComPPI
RBX1 DTL 25348397 N/A physical interaction ComPPI
RBX1 UVRAG 25348397 N/A physical interaction ComPPI
RBX1 FBXO7 25348397 N/A physical interaction ComPPI
RBX1 KLHL18 25348397 N/A physical interaction ComPPI
RBX1 AIRE 25348397 N/A physical interaction ComPPI
RBX1 FBXO32 25348397 N/A physical interaction ComPPI
RBX1 FXR1 25348397 N/A physical interaction ComPPI
RBX1 DNMT3A 25348397 N/A physical interaction ComPPI
RBX1 SUV39H1 25348397 N/A physical interaction ComPPI
RBX1 KMT5A 25348397 N/A physical interaction ComPPI
RBX1 UBXN1 25348397 N/A physical interaction ComPPI
RBX1 AHR 25348397 N/A physical interaction ComPPI
RBX1 FBXW5 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
RBX1 FBXO33 16797541 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
RBX1 CTNNB1 18805092 24234451 25348397 ubiquitination reaction enzymatic study ComPPI,IntAct
RBX1 SUZ12 23238014 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RBX1 CCNA2 16209941 24234451 25348397 association molecular sieving ComPPI,IntAct
RBX1 BECN1 23974797 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RBX1 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
CSNK1E RBX1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CBX5 RBX1 25348397 N/A physical interaction ComPPI
CDC34 RBX1 10713156 10748083 11463388 11675391 11927591 12435635 12565873 12813041 12840033 14532120 14578910 15327770 15531760 15980415 16009132 16123592 16322693 16338364 16861890 17965458 18239684 18805092 18851830 19112177 19581926 19933270 20081843 20160477 20353940 20596027 20638939 20663873 20832730 21070969 21130766 21220517 21841822 22017877 22113614 22334663 22608923 22669845 22711876 22959436 23297342 23478441 23589337 23770852 23910095 23972993 24129577 24234451 24316736 25149538 25202122 25348397 25515538 26407237 26649820 26818844 27898060 N/A nuclear magnetic resonance,physical interaction ComPPI,IntAct,OmniPath
DDA1 RBX1 25348397 N/A physical interaction ComPPI
DCUN1D5 RBX1 25348397 N/A physical interaction ComPPI
INAVA RBX1 24234451 29420262 association anti tag coimmunoprecipitation IntAct
RBX1 CUL1 10230406 10230407 10535940 10648623 10713156 10748083 11027288 11245432 11337588 11359933 11384984 11483504 11861641 11956208 11961546 12167173 12215511 12381738 12417738 12481031 12504025 12504026 12565873 12609982 12684064 12706828 12840033 12904573 15361859 15448697 15659098 15749712 15860010 16123592 16275325 16759355 16880526 17158585 17452440 18805092 18826954 19245792 19250909 19933270 19942853 20399188 20638939 20832730 21169563 21765416 22405651 22474075 22767593 22822056 23535663 23770852 24949976 26344197 26540345 26725323 27898060 stimulant N/A OmniPath
RBX1 TCF3 14592976 27898060 N/A N/A OmniPath
CASP3 RBX1 17217622 27898060 N/A N/A OmniPath
RBX1 NFKB1 11295495 27898060 stimulant N/A OmniPath
RBX1 NFKBIA 10230406 27898060 inhibition N/A OmniPath
RBX1 NFE2L2 15572695 27898060 inhibition N/A OmniPath
RBX1 UBE2M 11574546 12565873 16275327 17132228 17439941 18826954 19245792 19250909 19549727 20353940 21765416 24949976 25912140 27898060 stimulant N/A OmniPath
RBX1 NFKB2 14676825 27898060 stimulant N/A OmniPath

Visualization










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