GENE:AEBP2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | AEBP2 |
| FullNmae | AE binding protein 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:24051 |
| EnsembleID | ENSG00000139154 |
| Uniprot | Q6ZN18 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| AEBP2 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| AEBP2 | GO:0000122,GO:0000785,GO:0003677,GO:0003712,GO:0005654,GO:0005654,GO:0006325,GO:0006357,GO:0035098,GO:0035098,GO:0046872 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| AEBP2 | hsa:121536 | path:hsa03083 | Polycomb repressive complex - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | AEBP2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| TP73 | AEBP2 | 21245298 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| FOXP3 | AEBP2 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | AEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | AEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | AEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | AEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | AEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | AEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | AEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | AEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | AEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | AEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | AEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | AEBP2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000ED600 | AEBP2 | 20215506 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00005651EE | AEBP2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00005FDE70 | AEBP2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000000B1C9 | AEBP2 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000272039 | AEBP2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| RBBP4 | AEBP2 | 25361965 | interaction type | N/A | PTMCode2 |
| AEBP2 | RBBP4 | 25361965 | interaction type | N/A | PTMCode2 |
| EED | AEBP2 | 25361965 | interaction type | N/A | PTMCode2 |
| AEBP2 | EED | 25361965 | interaction type | N/A | PTMCode2 |
| SUZ12 | AEBP2 | 25361965 | interaction type | N/A | PTMCode2 |
| AEBP2 | SUZ12 | 25361965 | interaction type | N/A | PTMCode2 |
| JARID2 | AEBP2 | 25361965 | interaction type | N/A | PTMCode2 |
| AEBP2 | JARID2 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LDOC1 | AEBP2 | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| KBTBD7 | AEBP2 | 25348397 | N/A | physical interaction | ComPPI |
| EZH2 | AEBP2 | 24234451 25348397 27705803 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| BTRC | AEBP2 | 25348397 | N/A | physical interaction | ComPPI |
| PIGR | AEBP2 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| LTF | AEBP2 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| RBBP4 | AEBP2 | 14525934 15225548 24234451 25348397 27705803 | association | experimental interaction detection,physical interaction,in vitro,tandem affinity purification | ComPPI,HPRD,IntAct |
| PIP | AEBP2 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| S100A7 | AEBP2 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| EED | AEBP2 | 14525934 15225548 24234451 25348397 27705803 | association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,tandem affinity purification | ComPPI,HPRD,IntAct |
| ATXN3 | AEBP2 | 25348397 | N/A | physical interaction | ComPPI |
| LACRT | AEBP2 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| ELAVL1 | AEBP2 | 25348397 | N/A | physical interaction | ComPPI |
| EZH1 | AEBP2 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| AEBP2 | SUZ12 | 14525934 15225548 20075857 24234451 25348397 27705803 | association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,tandem affinity purification | ComPPI,HPRD,IntAct |
| AEBP2 | RALYL | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| AEBP2 | H1-1 | 25348397 | N/A | physical interaction | ComPPI |
| AEBP2 | H1-2 | 25348397 | N/A | physical interaction | ComPPI |
| AEBP2 | KMT5A | 25348397 | N/A | physical interaction | ComPPI |
| AEBP2 | APP | 25348397 | N/A | physical interaction | ComPPI |
| AEBP2 | JMJD6 | 23455924 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| AEBP2 | FBXW11 | 25348397 | N/A | physical interaction | ComPPI |
| AEBP2 | HMBOX1 | 25348397 | N/A | physical interaction | ComPPI |
| AEBP2 | JARID2 | 24234451 25348397 27705803 | association | anti tag coimmunoprecipitation,physical interaction,tandem affinity purification | ComPPI,IntAct |
| AEBP2 | RBBP7 | 24234451 25348397 27705803 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| AEBP2 | THAP1 | 25348397 | N/A | physical interaction | ComPPI |
| AEBP2 | RPL39 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| AEBP2 | LGALS7 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| AEBP2 | SCGB2A1 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| PHB2 | AEBP2 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| TTC9C | AEBP2 | 24234451 30021884 | physical association | cross-linking study | IntAct |
