GENE:AGPS
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | AGPS |
| FullNmae | alkylglycerone phosphate synthase |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:327 |
| EnsembleID | ENSG00000018510 |
| Uniprot | O00116 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| AGPS | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| AGPS | GO:0005515,GO:0005739,GO:0005777,GO:0005777,GO:0005778,GO:0005782,GO:0005829,GO:0008609,GO:0008609,GO:0008610,GO:0008610,GO:0008611,GO:0008611,GO:0016020,GO:0071949 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| AGPS | hsa:8540 | path:hsa00565 | Ether lipid metabolism - Homo sapiens (human) |
| AGPS | hsa:8540 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
| AGPS | hsa:8540 | path:hsa04146 | Peroxisome - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | AGPS | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | AGPS | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | AGPS | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| MYC | AGPS | 18414489 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| SMARCA4 | AGPS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | AGPS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | AGPS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | AGPS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | AGPS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | AGPS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | AGPS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | AGPS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | AGPS | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000122ED0 | AGPS | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000023133F | AGPS | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001310DE | AGPS | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000081D1E | AGPS | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004719AB | AGPS | 21572407 23313552 23446348 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | AGPS | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000427B68 | AGPS | 21572407 23313552 23446348 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000535FDD | AGPS | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | AGPS | 23446348 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F4657 | AGPS | 23313552 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000237AF9 | AGPS | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000045DBD | AGPS | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LGALS3 | AGPS | 25348397 | N/A | physical interaction | ComPPI |
| MCM2 | AGPS | 25348397 | N/A | physical interaction | ComPPI |
| EMC2 | AGPS | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CSRP2 | AGPS | 25348397 | N/A | physical interaction | ComPPI |
| AGPS | GNPAT | 10215861 14525934 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| AGPS | ATG16L1 | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| AGPS | ABCD3 | 25348397 | N/A | physical interaction | ComPPI |
| AGPS | ABCD1 | 25348397 | N/A | physical interaction | ComPPI |
| AGPS | IDH3G | 25348397 | N/A | physical interaction | ComPPI |
| AGPS | SCP2 | 25348397 | N/A | physical interaction | ComPPI |
| AGPS | PEX5 | 25348397 | N/A | physical interaction | ComPPI |
| AGPS | PEX14 | 21525035 24234451 25348397 | association | pull down,physical interaction | ComPPI,IntAct |
| AGPS | HDAC11 | 23752268 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| AGPS | PRKN | 25348397 | N/A | physical interaction | ComPPI |
| AGPS | MDM2 | 25348397 | N/A | physical interaction | ComPPI |
| AGPS | GORASP1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| AGPS | CCDC8 | 25348397 | N/A | physical interaction | ComPPI |
| AGPS | MRPL37 | 25348397 | N/A | physical interaction | ComPPI |
| AGPS | TMEM87A | 25348397 | N/A | physical interaction | ComPPI |
| AGPS | LMAN1 | 25348397 | N/A | physical interaction | ComPPI |
| AGPS | NTRK1 | 25348397 | N/A | physical interaction | ComPPI |
| AGPS | CHORDC1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| AGPS | PARD6B | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| AGPS | NCDN | 25348397 | N/A | physical interaction | ComPPI |
| AGPS | PDHA1 | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
| AGPS | RIPK4 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| AGPS | CAT | 24234451 25348397 29568061 | association | pull down,proximity-dependent biotin identification | ComPPI,IntAct |
| HSCB | AGPS | 24234451 25348397 28380382 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
