GENE：PEX2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PEX2 |
| FullNmae | peroxisomal biogenesis factor 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:9717 |
| EnsembleID | ENSG00000164751 |
| Uniprot | P28328 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PEX2 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PEX2 | GO:0000038,GO:0000038,GO:0000425,GO:0005515,GO:0005778,GO:0005778,GO:0005778,GO:0005778,GO:0005829,GO:0006635,GO:0006635,GO:0007031,GO:0007031,GO:0008270,GO:0008320,GO:0016020,GO:0016558,GO:0016562,GO:0016567,GO:0016593,GO:0016593,GO:0031648,GO:0034614,GO:0044721,GO:0048147,GO:0050680,GO:0061630,GO:0061630,GO:1990928 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| PEX2 | hsa:5828 | path:hsa04146 | Peroxisome - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | PEX2 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| ETS1 | PEX2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | PEX2 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | PEX2 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | PEX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | PEX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | PEX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | PEX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | PEX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | PEX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | PEX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | PEX2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000007FBA | PEX2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000036B845 | PEX2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001E0AEA | PEX2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000077AED | PEX2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000250A40 | PEX2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031D186 | PEX2 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004E008F | PEX2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000078918 | PEX2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005CCD18 | PEX2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000486E0B | PEX2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AD2AA | PEX2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029D793 | PEX2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000021D08 | PEX2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006F90B | PEX2 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075B538 | PEX2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000083D87 | PEX2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000008A99 | PEX2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000759B6A | PEX2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000221168 | PEX2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | PEX2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000160683 | PEX2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | PEX2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000001C659 | PEX2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000045B99E | PEX2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000202460 | PEX2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TLE1 | PEX2 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| PEX2 | ERG28 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| PEX2 | APP | 25348397 | N/A | physical interaction | ComPPI |
| PEX2 | PEX5 | 25348397 | N/A | physical interaction | ComPPI |
| PEX2 | PEX14 | 21525035 24234451 25348397 | association | pull down,physical interaction | ComPPI,IntAct |
| PEX2 | UBE2A | 19410543 24234451 25348397 | association | pull down | ComPPI,IntAct |
| PEX2 | PEX19 | 20531392 24234451 25348397 | N/A | peptide array | ComPPI,IntAct |