Gene Information gene info

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GENE：PEX6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PEX6
FullNmae peroxisomal biogenesis factor 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8859
EnsembleID ENSG00000124587
Uniprot Q13608

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PEX6 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PEX6 GO:0001750,GO:0005515,GO:0005524,GO:0005737,GO:0005777,GO:0005778,GO:0005778,GO:0005829,GO:0005829,GO:0005829,GO:0006625,GO:0007031,GO:0016558,GO:0016561,GO:0016562,GO:0016887,GO:0016887,GO:0043335,GO:0044877,GO:0050821,GO:0097733,GO:0140036,GO:0140318

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PEX6 hsa:5190 path:hsa04146 Peroxisome - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 PEX6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PEX6 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PEX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PEX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PEX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PEX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PEX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PEX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PEX6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SMAD3 PEX6 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001C770D PEX6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 PEX6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 PEX6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000553F51 PEX6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000334286 PEX6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 PEX6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005586D0 PEX6 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PEX6 PEX26 25361965 interaction type N/A PTMCode2
PEX26 PEX6 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PSMC3 PEX6 25348397 N/A physical interaction ComPPI
SMAD3 PEX6 14525934 14651998 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
THBS3 PEX6 25348397 N/A physical interaction ComPPI
CERS2 PEX6 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ENSA PEX6 25348397 N/A physical interaction ComPPI
CD79A PEX6 25348397 N/A physical interaction ComPPI
PEX1 PEX6 14525934 15634331 16007078 16911527 22500805 22710083 22940862 24234451 25348397 25659908 26066397 27898060 9588209 9671729 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct,OmniPath
PEX6 PEX26 12717447 14525934 16257970 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PEX6 RPL27A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PEX6 TMEM25 25348397 N/A physical interaction ComPPI
PEX6 THBS4 25348397 N/A physical interaction ComPPI
PEX6 DKKL1 25348397 N/A physical interaction ComPPI
PEX6 KBTBD4 25348397 N/A physical interaction ComPPI
PEX6 IMPDH1 25348397 N/A physical interaction ComPPI
PEX6 OLFM2 25348397 N/A physical interaction ComPPI
PEX6 LNX1 25348397 N/A physical interaction ComPPI
PEX6 ATF7IP 14525934 15231748 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
RPS14 PEX6 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct

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