GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
FAR1 |
| FullNmae |
fatty acyl-CoA reductase 1 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:26222 |
| EnsembleID |
ENSG00000197601 |
| Uniprot |
Q8WVX9 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| FAR1 |
ferroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| FAR1 |
GO:0005515,GO:0005777,GO:0005777,GO:0005778,GO:0005778,GO:0005778,GO:0008611,GO:0008611,GO:0010025,GO:0010025,GO:0016491,GO:0035336,GO:0035336,GO:0046474,GO:0080019,GO:0080019,GO:0102965 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| ETS1 |
FAR1 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| GATA2 |
FAR1 |
18971253
19941826
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| YBX1 |
FAR1 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| SMARCA4 |
FAR1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
FAR1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| E2F4 |
FAR1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
FAR1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
FAR1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOS |
FAR1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| VDR |
FAR1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS0000338542 |
FAR1 |
N/A
|
rna interference,inhibition |
experimental interaction detection |
miRSponge |
| URS0000338542 |
FAR1 |
18668040
22473208
25416803
|
mrna cleavage,inhibition |
experimental interaction detection,clip |
TarBase |
| URS00000DDD35 |
FAR1 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS00005651EE |
FAR1 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS00002FC5B0 |
FAR1 |
22473208
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00001A7F58 |
FAR1 |
22473208
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| CUL5 |
FAR1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ATXN1 |
FAR1 |
23275563
24234451
25348397
|
physical association |
physical interaction,two hybrid prey pooling approach |
ComPPI,IntAct |
| KEAP1 |
FAR1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CUL3 |
FAR1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| SLC2A4 |
FAR1 |
14525934
16396496
25348397
|
N/A |
experimental interaction detection,physical interaction,in vivo |
ComPPI,HPRD |
| FAR1 |
IQCB1 |
21565611
24234451
25348397
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| FAR1 |
PEX14 |
21525035
24234451
25348397
|
association |
pull down,physical interaction |
ComPPI,IntAct |
| FAR1 |
CLN3 |
25348397
|
N/A |
physical interaction |
ComPPI |
| FAR1 |
EGFR |
25348397
|
N/A |
physical interaction |
ComPPI |
| FAR1 |
CYLD |
25348397
|
N/A |
physical interaction |
ComPPI |
| FAR1 |
CFTR |
25348397
|
N/A |
physical interaction |
ComPPI |
| FAR1 |
RIPK4 |
24234451
25348397
26972000
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
| FAR1 |
KSR1 |
24234451
25348397
27086506
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
| FAR1 |
TUBA1A |
24234451
25348397
29568061
|
association |
pull down |
ComPPI,IntAct |
| MAPK6 |
FAR1 |
24234451
25348397
26972000
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
| ECH1 |
FAR1 |
24234451
25348397
29426014
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
| CDK1 |
FAR1 |
21658602
24019491
24186061
25049391
27898060
8066461
8395009
8500168
9367986
9632750
|
N/A |
N/A |
OmniPath |
Visualization