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GENE：SMAD7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SMAD7
FullNmae SMAD family member 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6773
EnsembleID ENSG00000101665
Uniprot O15105

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SMAD7 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SMAD7 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SMAD7 apoptosis 35795857 Abnormal Smad7 expression can lead to apoptosis in different cell types. retulator signature

Go Annotation:

GeneSymbol Go id
SMAD7 GO:0000122,GO:0000785,GO:0001650,GO:0001657,GO:0002725,GO:0005515,GO:0005518,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005813,GO:0005829,GO:0005829,GO:0005886,GO:0005912,GO:0006357,GO:0007179,GO:0008013,GO:0009653,GO:0010717,GO:0010719,GO:0010801,GO:0010944,GO:0022409,GO:0030154,GO:0030279,GO:0030336,GO:0030512,GO:0030512,GO:0030514,GO:0031397,GO:0031503,GO:0031625,GO:0032436,GO:0032926,GO:0032991,GO:0033137,GO:0034333,GO:0034616,GO:0034713,GO:0043433,GO:0046872,GO:0048844,GO:0050821,GO:0051444,GO:0055010,GO:0055117,GO:0060373,GO:0060392,GO:0060392,GO:0060395,GO:0060412,GO:0070411,GO:0070411,GO:0070697,GO:0071144,GO:0071560,GO:0140416,GO:0140416,GO:1902731,GO:1903043,GO:1990756,GO:1990830,GO:2000317,GO:2000320

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SMAD7 hsa:4092 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)
SMAD7 hsa:4092 path:hsa04390 Hippo signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMAD2 SMAD7 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 26192618 9670020 association N/A ACSN
SMAD3 SMAD7 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 26192618 8515656 association N/A ACSN
SMAD7 SMAD4 11279127 15265520 19032343 23180781 23784029 26192618 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
SMAD7 TGFBR1 11279127 14657019 14722617 15148321 15265520 17314099 18988627 21071413 21791611 22286770 23331499 23784029 26192618 9215638 interaction type,stimulation N/A ACSN,SignaLink,SignaLink
TGFB1 SMAD7 11133108 11708773 12490555 14557817 15111329 15181457 15252039 15548370 16474430 16607286 16716598 17615296 17934056 18403754 19010789 19109155 19920116 20519943 20644162 21041997 21278795 21900405 21909923 22703233 26192618 7594497 9157999 9335507 interaction type N/A ACSN
SMAD7 TAB2 17384642 23180781 23331499 stimulation,physical association anti tag coimmunoprecipitation,two hybrid InnateDB,SignaLink
SMAD7 TAB1 11737269 23180781 23331499 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink
SMAD7 TAB3 17384642 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD7 MAPK14 12589052 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD7 MAP3K7 12589052 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD7 CTNNB1 15684397 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD7 LEF1 15684397 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD7 ITCH 15946939 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD7 FKBP1A 16720724 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
SMAD7 ACVR1B 16720724 23180781 physical association pull down InnateDB
SMAD7 SMURF1 16720724 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMURF1 SMAD7 11278251 12151385 12408818 12519765 14722617 15221015 16720724 18988627 21071413 23180781 23331499 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink,SignaLink
SMAD7 SERPINE1 17438144 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD7 HDAC1 19049980 23180781 physical association anti tag coimmunoprecipitation InnateDB
PRMT5 SMAD7 19032343 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD7 HDAC3 19032343 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD7 TBL1XR1 19032343 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD7 SKI 19032343 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD7 STAMBPL1 14728725 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD7 EGR1 20690147 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMAD7 SMAD3 21071413 21625455 23180781 23331499 9892009 9892110 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink,SignaLink
SMAD7 SMAD7 11163210 17438144 19352540 20663871 21791611 26467481 9892110 interaction type,bind,up-regulates activity,down-regulates,down-regulates activity,relocalization reaction N/A Signor
SMAD7 SMAD2 17438144 21071413 23331499 9892009 9892110 stimulation N/A SignaLink,SignaLink
SMAD7 BMPR1A 10564272 23331499 stimulation N/A SignaLink,SignaLink
SMAD7 ACVR1 10564272 23331499 stimulation N/A SignaLink,SignaLink
SMAD7 ACVRL1 12023024 23331499 stimulation N/A SignaLink,SignaLink
CTNNB1 SMAD7 15684397 18988627 21071413 23331499 stimulation N/A SignaLink,SignaLink
SIRT1 SMAD7 17098745 21071413 23331499 stimulation N/A SignaLink,SignaLink
ITCH SMAD7 15946939 19030025 21071413 23331499 stimulation N/A SignaLink,SignaLink
SIK1 SMAD7 19030025 23331499 stimulation N/A SignaLink,SignaLink
SMURF2 SMAD7 22921829 interaction type,stimulation N/A SignaLink
NEDD4L SMAD7 15496141 22921829 23331499 interaction type,stimulation N/A SignaLink,SignaLink
RLIM SMAD7 22560923 ubiquitination reaction,inhibition N/A SignaLink
TGFB1I1 SMAD7 21996749 interaction type,inhibition N/A SignaLink
SMAD7 BMPR1B 10564272 23331499 stimulation N/A SignaLink
SMAD7 SMURF2 11163210 18448069 20937913 23331499 stimulation N/A SignaLink
KAT2A SMAD7 12408818 23331499 stimulation N/A SignaLink
RNF111 SMAD7 14657019 23331499 stimulation N/A SignaLink
SMAD7 PPP1R15A 14718519 23331499 stimulation N/A SignaLink
WWP1 SMAD7 15221015 23331499 stimulation N/A SignaLink
UCHL5 SMAD7 16027725 23331499 stimulation N/A SignaLink
SMAD7 PPP1CA 16571110 23331499 stimulation N/A SignaLink
SMAD7 MAP3K1 10085121 23331499 inhibition N/A SignaLink
EP300 SMAD7 12408818 21269274 23331499 stimulation N/A SignaLink
SMAD7 STRAP 10757800 17314099 23331499 stimulation N/A SignaLink
YAP1 SMAD7 12118366 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR SMAD7 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SMAD7 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SMAD7 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 SMAD7 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 SMAD7 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMAD3 SMAD7 10559222 10823886 12761881 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
SMAD4 SMAD7 10559222 10823886 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
MYC SMAD7 12695333 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SKI SMAD7 15128733 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SKIL SMAD7 16442497 23154975 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 SMAD7 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 SMAD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SMAD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SMAD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SMAD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SMAD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SMAD7 15579469 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SMAD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SMAD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SMAD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HDAC1 SMAD7 24369345 trascriptional regulation,stimulation inferred by curator TFlink
JUN SMAD7 15579469 trascriptional regulation,stimulation inferred by curator TFlink
MTA1 SMAD7 22841502 trascriptional regulation,stimulation inferred by curator TFlink
YY1 SMAD7 24369345 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D SMAD7 23292313 rna interference,inhibition western blot,quantitative reverse transcription pcr miRSponge
URS000013ABA3 SMAD7 23471579 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000060B2B SMAD7 23471579 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000C85B2 SMAD7 23435373 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000060B2B SMAD7 23471579 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000013ABA3 SMAD7 23471579 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000C85B2 SMAD7 22286770 23435373 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000009262D SMAD7 23292313 24887517 25416803 26575121 28192117 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,immunocytochemistry,miRNA interference luciferase reporter assay TarBase
URS0000122ED0 SMAD7 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 SMAD7 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000041CB9C SMAD7 20371350 21572407 23446348 23622248 24398324 24435757 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,clash,miRNA interference luciferase reporter assay TarBase
URS00001A405B SMAD7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F SMAD7 23665284 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000600E6 SMAD7 22286770 25286029 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000DDD35 SMAD7 22286770 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000CBE63 SMAD7 25416803 25880168 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS0000021D08 SMAD7 25416803 25436421 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00001EFEC1 SMAD7 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000058BB84 SMAD7 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC SMAD7 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 SMAD7 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000075C3F6 SMAD7 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC SMAD7 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 SMAD7 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 SMAD7 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD SMAD7 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 SMAD7 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D SMAD7 20371350 21572407 23446348 24398324 25416803 26837421 27574009 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000007D64A SMAD7 20371350 21572407 23446348 24398324 25416803 27303812 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00000F0F49 SMAD7 20371350 21572407 23446348 24398324 25416803 27628042 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000171CD1 SMAD7 20371350 21572407 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 SMAD7 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 SMAD7 22473208 25416803 27100897 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS00002367FA SMAD7 25416803 26390174 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000298BA3 SMAD7 25416803 27006642 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000272039 SMAD7 25416803 27192628 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
SMAD7 AXIN1 25361965 interaction type N/A PTMCode2
AXIN1 SMAD7 25361965 interaction type N/A PTMCode2
SMAD7 SMURF2 25361965 interaction type N/A PTMCode2
SMURF2 SMAD7 25361965 interaction type N/A PTMCode2
SMAD7 BMPR1B 25361965 interaction type N/A PTMCode2
BMPR1B SMAD7 25361965 interaction type N/A PTMCode2
SMAD7 WWP1 25361965 interaction type N/A PTMCode2
WWP1 SMAD7 25361965 interaction type N/A PTMCode2
SMAD7 AKT1 25361965 interaction type N/A PTMCode2
AKT1 SMAD7 25361965 interaction type N/A PTMCode2
SMAD7 RNF111 25361965 interaction type N/A PTMCode2
RNF111 SMAD7 25361965 interaction type N/A PTMCode2
SMAD7 SMAD6 25361965 interaction type N/A PTMCode2
SMAD6 SMAD7 25361965 interaction type N/A PTMCode2
SMAD7 SMAD4 25361965 interaction type N/A PTMCode2
SMAD4 SMAD7 25361965 interaction type N/A PTMCode2
SMAD7 CTNNB1 25361965 interaction type N/A PTMCode2
CTNNB1 SMAD7 25361965 interaction type N/A PTMCode2
SMAD7 STAMBP 25361965 interaction type N/A PTMCode2
STAMBP SMAD7 25361965 interaction type N/A PTMCode2
SMAD7 MAP2K3 25361965 interaction type N/A PTMCode2
MAP2K3 SMAD7 25361965 interaction type N/A PTMCode2
SMAD7 TGFBR2 25361965 interaction type N/A PTMCode2
TGFBR2 SMAD7 25361965 interaction type N/A PTMCode2
SMAD7 ITCH 25361965 interaction type N/A PTMCode2
ITCH SMAD7 25361965 interaction type N/A PTMCode2
MYOD1 SMAD7 25361965 interaction type N/A PTMCode2
SMAD7 MYOD1 25361965 interaction type N/A PTMCode2
BMPR1A SMAD7 25361965 interaction type N/A PTMCode2
SMAD7 BMPR1A 25361965 interaction type N/A PTMCode2
MAPK14 SMAD7 25361965 interaction type N/A PTMCode2
SMAD7 MAPK14 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HAT1 SMAD7 12408818 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
FKBP1A SMAD7 16720724 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
SMAD4 SMAD7 15128733 19032343 24234451 25348397 association physical interaction,chromatin immunoprecipitation assay ComPPI,IntAct
TAB3 SMAD7 25348397 N/A physical interaction ComPPI
HEYL SMAD7 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ERBIN SMAD7 25348397 N/A physical interaction,in vitro ComPPI
SMURF2 SMAD7 11163210 14525934 15231748 17719543 20937913 22921829 24234451 25348397 physical association classical fluorescence spectroscopy,two hybrid,experimental interaction detection,isothermal titration calorimetry,nuclear magnetic resonance,physical interaction,in vitro,in vivo,ion mobility mass spectrometry of complexes,two hybrid ComPPI,HPRD,IntAct
SMAD1 SMAD7 25348397 N/A physical interaction ComPPI
CBL SMAD7 25348397 N/A physical interaction ComPPI
TGFBR2 SMAD7 11163210 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RNF111 SMAD7 14525934 14657019 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SMAD7 ZNF107 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMAD7 ZBTB44 14525934 15231748 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
SMAD7 TTF2 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMAD7 MYOD1 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMAD7 SOX5 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMAD7 ASH1L 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMAD7 ZBTB11 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMAD7 SOX13 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMAD7 TTF1 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMAD7 MAPK14 12589052 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SMAD7 MAP2K6 12589052 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SMAD7 ACVR1B 12023024 14525934 16720724 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
SMAD7 MAP2K3 25348397 N/A physical interaction,in vitro,in vivo ComPPI
SMAD7 MAP3K7 12589052 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SMAD7 EP300 12408818 14525934 24234451 25303530 25348397 association experimental interaction detection,physical interaction,chromatin immunoprecipitation assay,in vitro,in vivo ComPPI,HPRD,IntAct
SMAD7 SMAD6 14525934 25348397 9256479 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SMAD7 STRAP 10757800 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SMAD7 STAMBP 11483516 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SMAD7 PKHD1 25348397 N/A two hybrid,in vitro ComPPI
SMAD7 PARD3 12650946 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
SMAD7 SMURF1 11278251 12151385 12519765 14525934 25348397 N/A experimental interaction detection,isothermal titration calorimetry,nuclear magnetic resonance,physical interaction,in vitro,in vivo,ion mobility mass spectrometry of complexes ComPPI,HPRD
SMAD7 PIAS4 12815042 14525934 15231748 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
SMAD7 YAP1 12118366 14525934 22921829 24234451 25283809 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,isothermal titration calorimetry,nuclear magnetic resonance,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
SMAD7 STAMBPL1 14525934 14728725 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SMAD7 BMPR1B 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMAD7 DVL1 12650946 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
SMAD7 SASH3 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMAD7 AXIN1 14525934 16601693 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,imaging technique,in vitro,in vivo ComPPI,HPRD,IntAct
SMAD7 AKT1 14525934 16362038 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SMAD7 CTNNB1 14525934 15684397 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SMAD7 PIAS1 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMAD7 XRCC6 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMAD7 KDM2A 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMAD7 MBD1 14525934 15231748 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
SMAD7 CXXC5 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMAD7 SOX7 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMAD7 BMPR1A 25348397 N/A physical interaction ComPPI
SMAD7 TGFBR1 14525934 15148321 25348397 9215638 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SMAD7 LEF1 25348397 N/A physical interaction ComPPI
SMAD7 DVL1P1 25348397 N/A physical interaction ComPPI
SMAD7 TAB1 11737269 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SMAD7 KAT2B 25348397 N/A physical interaction ComPPI
SMAD7 UCHL5 25348397 N/A physical interaction ComPPI
SMAD7 ITCH 25348397 N/A physical interaction ComPPI
SMAD7 HDAC1 25348397 N/A physical interaction ComPPI
SMAD7 HDAC2 25348397 N/A physical interaction ComPPI
SMAD7 HDAC3 19032343 24234451 25348397 association physical interaction,chromatin immunoprecipitation assay ComPPI,IntAct
SMAD7 HDAC5 25348397 N/A physical interaction ComPPI
SMAD7 HDAC6 25348397 N/A physical interaction ComPPI
SMAD7 NEDD4 25348397 N/A physical interaction ComPPI
SMAD7 SRF 25348397 N/A physical interaction ComPPI
SMAD7 WWP1 25348397 N/A physical interaction ComPPI
SMAD7 SMAD2 25348397 N/A physical interaction ComPPI
SMAD7 SIRT1 17098745 24234451 25348397 N/A pull down,physical interaction ComPPI,IntAct
SMAD7 ZEB1 20514018 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SMAD7 TSC22D1 25348397 N/A physical interaction ComPPI
SMAD7 WWP2 21258410 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
SMAD7 USP11 25348397 N/A physical interaction ComPPI
SMAD7 UBE2L3 25348397 N/A physical interaction ComPPI
SMAD7 USP15 25348397 N/A physical interaction ComPPI
SMAD7 COPS5 14993265 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,confocal microscopy ComPPI,IntAct
SMAD7 TAB2 25348397 N/A physical interaction ComPPI
SMAD7 TOLLIP 25348397 N/A physical interaction ComPPI
SMAD7 TP53 25348397 N/A physical interaction ComPPI
SMAD7 ATM 25348397 N/A physical interaction ComPPI
SMAD7 TGFB1I1 18762808 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SMAD7 PPP1R15A 25348397 N/A physical interaction ComPPI
SMAD7 BAMBI 25348397 N/A physical interaction ComPPI
SMAD7 CDH1 25348397 N/A physical interaction ComPPI
SMAD7 BMPR2 25348397 N/A physical interaction ComPPI
SMAD7 ACVR1 25348397 N/A physical interaction ComPPI
SMAD7 ACVR2B 25348397 N/A physical interaction ComPPI
SMAD7 UBE2O 25348397 N/A physical interaction ComPPI
SMAD7 MRTFB 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMAD7 MYC 25348397 N/A physical interaction ComPPI
SMAD7 SKP2 25348397 N/A physical interaction ComPPI
SMAD7 TCF7L2 25348397 N/A physical interaction ComPPI
SMAD7 NR4A1 25348397 N/A physical interaction ComPPI
SMAD7 AXIN2 25348397 N/A physical interaction ComPPI
SMAD7 SMAD3 25348397 N/A physical interaction ComPPI
SMAD7 SMAD9 25348397 N/A physical interaction ComPPI
SMAD7 SETD7 25348397 N/A physical interaction ComPPI
SMAD7 UBC 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
SMAD7 UBA52 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
SMAD7 RNF165 23610558 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBB SMAD7 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
RPS27A SMAD7 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
NEDD4L SMAD7 25348397 N/A anti tag coimmunoprecipitation,isothermal titration calorimetry,isothermal titration calorimetry,nuclear magnetic resonance,physical interaction,physical interaction ComPPI
SMAD7 SMAD7 12589052 14525934 N/A experimental interaction detection HPRD
SMAD7 SKI 15128733 19032343 24234451 association chromatin immunoprecipitation assay IntAct
PRMT5 SMAD7 19032343 24234451 association chromatin immunoprecipitation assay IntAct
SMAD7 TBL1XR1 19032343 24234451 association chromatin immunoprecipitation assay IntAct
SMAD7 CBLB 23709694 27898060 N/A N/A OmniPath
CTNNB1 SMAD7 15684397 18593713 27898060 stimulant N/A OmniPath
ITCH SMAD7 15946939 1594694 19030025 22773947 27898060 inhibition,stimulant N/A OmniPath
SMAD7 MAP3K7 12589052 27898060 stimulant N/A OmniPath
MAP3K7 SMAD7 12589052 27898060 N/A N/A OmniPath
YAP1 SMAD7 12118366 22921829 25283809 27898060 stimulant N/A OmniPath
UCHL5 SMAD7 16027725 27898060 stimulant N/A OmniPath
SMAD7 MAP3K1 10085121 27898060 inhibition N/A OmniPath
KAT2A SMAD7 12408818 27898060 stimulant N/A OmniPath
SMAD7 STRAP 107578 10757800 17314099 27898060 stimulant N/A OmniPath
SMAD7 PPP1R15A 14718519 27898060 stimulant N/A OmniPath
SMAD7 SMAD1 17438144 27898060 inhibition N/A OmniPath
SIRT1 SMAD7 17098745 27898060 inhibition,stimulant N/A OmniPath
HDAC3 SMAD7 15831498 15831516 23213415 27898060 stimulant N/A OmniPath
MAPK14 SMAD7 12589052 17172861 27898060 N/A N/A OmniPath
SMAD7 SMAD2 17438144 26555259 27898060 9892009 9892110 inhibition,stimulant N/A OmniPath
SMAD7 TAB2 17384642 27898060 stimulant N/A OmniPath
TAB2 SMAD7 17384642 27898060 N/A N/A OmniPath
SMAD7 PPP1CA 16571110 27898060 stimulant N/A OmniPath
EP300 SMAD7 12408818 15831498 2126927 27898060 stimulant N/A OmniPath
AXIN1 SMAD7 16601693 27898060 inhibition,stimulant N/A OmniPath
SMAD7 SMAD4 10559222 15817471 17438144 26555259 27898060 stimulant N/A OmniPath
SMAD7 TAB1 11737269 12589052 27898060 inhibition,stimulant N/A OmniPath
SMAD7 TGFBR1 10757800 11163210 12151385 14657019 14722617 15148321 15359284 15946939 16027725 17314099 19758997 20663871 21791611 22624557 23027871 25149540 27898060 9215638 9335507 9738003 9892110 inhibition,stimulant N/A OmniPath
SMAD7 SMAD3 10559222 26555259 27898060 9892110 inhibition,stimulant N/A OmniPath
WWP1 SMAD7 15221015 15359284 22773947 27898060 stimulant N/A OmniPath
SMAD7 BMPR1A 10564272 15148321 20663871 27898060 stimulant N/A OmniPath
NEDD4L SMAD7 15496141 22773947 22921829 27898060 stimulant N/A OmniPath
RNF111 SMAD7 14657019 17347560 20386537 23530056 27898060 inhibition,stimulant N/A OmniPath
SMAD7 BMPR1B 10564272 15761153 27898060 inhibition,stimulant N/A OmniPath
SMAD7 ACVR1 10564272 27898060 stimulant N/A OmniPath
SMAD7 SMURF2 11163210 14722617 15173588 15221015 15231748 16061177 16641086 17347560 17719543 18448069 19352540 20386537 20937913 21791611 22624557 22773947 22921829 23973329 25612247 25885904 26679521 27898060 stimulant N/A OmniPath
SMURF2 SMAD7 11163210 14722617 15173588 15221015 15231748 16061177 16641086 17347560 17719543 18448069 19352540 20386537 20937913 21791611 22624557 22773947 22921829 23973329 25612247 25885904 26679521 27898060 inhibition N/A OmniPath
SMAD7 SMURF1 11278251 12151385 12408818 12519765 14722617 15221015 16720724 19352540 20937913 21791611 22152476 22773947 22921829 23959799 24700460 27898060 stimulant N/A OmniPath
SMURF1 SMAD7 11278251 12151385 12408818 12519765 14722617 15221015 16720724 19352540 20937913 21791611 22152476 22773947 22921829 23959799 24700460 27898060 inhibition,stimulant N/A OmniPath
SMAD7 TAB3 17384642 27898060 stimulant N/A OmniPath
TAB3 SMAD7 17384642 27898060 N/A N/A OmniPath
SMAD7 ACVRL1 12023024 27898060 inhibition,stimulant N/A OmniPath
HAT1 SMAD7 12408818 27898060 N/A N/A OmniPath

Visualization










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