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GENE：BRD7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BRD7
FullNmae bromodomain containing 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:14310
EnsembleID ENSG00000166164
Uniprot Q9NPI1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BRD7 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BRD7 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
BRD7 GO:0000776,GO:0000785,GO:0000976,GO:0002039,GO:0003713,GO:0003714,GO:0003714,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0006338,GO:0006357,GO:0006357,GO:0006357,GO:0007049,GO:0007346,GO:0016055,GO:0016363,GO:0016586,GO:0030071,GO:0042393,GO:0045582,GO:0045597,GO:0045663,GO:0045815,GO:0045892,GO:0045893,GO:0070316,GO:0070577,GO:0070577,GO:2000045,GO:2000134,GO:2000781,GO:2000819

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
BRD7 hsa:29117 path:hsa03082 ATP-dependent chromatin remodeling - Homo sapiens (human)
BRD7 hsa:29117 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BRD7 LEF1 17666529 21358755 22290435 22761862 26192618 interaction type N/A ACSN
BRD7 IRF2 11025449 23180781 physical association two hybrid,pull down InnateDB
BRD7 HNRNPUL1 12489984 23180781 physical association anti tag coimmunoprecipitation,two hybrid,pull down InnateDB
BRD7 H2BC21 12489984 23180781 physical association pull down InnateDB
BRD7 H3-4 12489984 23180781 physical association pull down InnateDB
H4C1 BRD7 12489984 23180781 physical association pull down InnateDB
BRD7 BRD2 16786191 23180781 physical association anti tag coimmunoprecipitation InnateDB
H3C1 BRD7 16265664 23180781 physical association anti tag coimmunoprecipitation InnateDB
H2AC12 BRD7 12489984 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 BRD7 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 BRD7 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC BRD7 19111069 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
SP1 BRD7 16792505 19111069 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
FOXP3 BRD7 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 BRD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA BRD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF BRD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 BRD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 BRD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS BRD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A BRD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 BRD7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F6 BRD7 16792505 trascriptional regulation,stimulation inferred by curator TFlink
MAX BRD7 19111069 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 BRD7 16792505 19111069 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000171525 BRD7 22015043 rna interference,inhibition array technology,western blot,immunohistochemistry,miRNA interference luciferase reporter assay miRSponge
URS0000171525 BRD7 22015043 25416803 mrna cleavage,inhibition array technology,western blot,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000002103A BRD7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000070B1D BRD7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000157026 BRD7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000239117 BRD7 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0874 BRD7 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 BRD7 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 BRD7 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D BRD7 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001FFA8C BRD7 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000031BC7D BRD7 20371350 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MYC BRD7 25361965 interaction type N/A PTMCode2
BRD7 MYC 25361965 interaction type N/A PTMCode2
SMARCA4 BRD7 25361965 interaction type N/A PTMCode2
BRD7 SMARCA4 25361965 interaction type N/A PTMCode2
IRF2 BRD7 25361965 interaction type N/A PTMCode2
BRD7 IRF2 25361965 interaction type N/A PTMCode2
SMARCC1 BRD7 25361965 interaction type N/A PTMCode2
BRD7 SMARCC1 25361965 interaction type N/A PTMCode2
SMARCE1 BRD7 25361965 interaction type N/A PTMCode2
BRD7 SMARCE1 25361965 interaction type N/A PTMCode2
DVL1 BRD7 25361965 interaction type N/A PTMCode2
BRD7 DVL1 25361965 interaction type N/A PTMCode2
BRD3 BRD7 25361965 interaction type N/A PTMCode2
BRD7 BRD3 25361965 interaction type N/A PTMCode2
HNRNPUL1 BRD7 25361965 interaction type N/A PTMCode2
BRD7 HNRNPUL1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2I BRD7 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
TFAP4 BRD7 25348397 N/A physical interaction ComPPI
SMARCE1 BRD7 25348397 N/A physical interaction ComPPI
CDC5L BRD7 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PLEKHF2 BRD7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BHLHE40 BRD7 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
AGR2 BRD7 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FTH1 BRD7 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SMARCC1 BRD7 25348397 N/A physical interaction ComPPI
PCBD1 BRD7 25348397 N/A physical interaction ComPPI
H2AC11 BRD7 25348397 N/A in vitro ComPPI
H4C1 BRD7 12489984 24234451 25348397 physical association pull down,in vitro ComPPI,IntAct
SMARCD1 BRD7 25348397 N/A physical interaction ComPPI
EP300 BRD7 20228809 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PSMD11 BRD7 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PRKAR1A BRD7 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SMARCA4 BRD7 25348397 N/A physical interaction ComPPI
TRIM24 BRD7 25348397 N/A physical interaction ComPPI
H2BC21 BRD7 25348397 N/A in vitro ComPPI
RPLP1 BRD7 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
DVL1 BRD7 25348397 N/A two hybrid,in vitro,in vivo ComPPI
H3-4 BRD7 25348397 N/A in vitro ComPPI
H3C15 BRD7 25348397 N/A physical interaction ComPPI
BRD2 BRD7 16786191 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HAP1 BRD7 25348397 N/A two hybrid,physical interaction ComPPI
CEP126 BRD7 15383276 24234451 25348397 physical association two hybrid ComPPI,IntAct
PTPN13 BRD7 10526152 25348397 27898060 N/A two hybrid,in vivo ComPPI,OmniPath
H3C1 BRD7 12489984 24234451 25348397 29568061 association,physical association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HNRNPUL1 BRD7 12489984 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,two hybrid,fluorescence technology,pull down,physical interaction,in vitro,in vivo ComPPI,IntAct
BARD1 BRD7 15383276 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GTF3C3 BRD7 25348397 N/A physical interaction ComPPI
BRD7 RIF1 25348397 N/A two hybrid ComPPI
BRD7 BRD3 25348397 N/A two hybrid ComPPI
BRD7 LAMA4 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
BRD7 BTBD2 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
BRD7 IRF2 25348397 N/A physical interaction ComPPI
BRD7 BRCA1 25348397 N/A physical interaction ComPPI
BRD7 POU2F1 25348397 N/A physical interaction ComPPI
BRD7 RBFOX2 25348397 N/A physical interaction ComPPI
BRD7 BCL7C 25348397 N/A physical interaction ComPPI
BRD7 ARID2 25348397 N/A physical interaction ComPPI
BRD7 CHD7 20130577 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BRD7 SMARCC2 25348397 N/A physical interaction ComPPI
BRD7 LRIF1 15383276 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BRD7 DPF3 25348397 N/A physical interaction ComPPI
BRD7 NUP50 25348397 N/A physical interaction ComPPI
BRD7 TP53 20228809 20660729 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,confocal microscopy ComPPI,IntAct
BRD7 GTF3C5 25348397 N/A physical interaction ComPPI
BRD7 PBRM1 25348397 N/A physical interaction ComPPI
BRD7 MX1 25348397 N/A physical interaction ComPPI
BRD7 REEP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRD7 BCL7A 25348397 N/A physical interaction ComPPI
BRD7 DLST 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
BRD7 H2BC1 12489984 24234451 25348397 physical association pull down ComPPI,IntAct
BRD7 H2AC1 12489984 24234451 25348397 physical association pull down ComPPI,IntAct
PAFAH1B3 BRD7 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SERPINB9 BRD7 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
NEFL BRD7 15383276 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MKI67 BRD7 24234451 26949251 association anti tag coimmunoprecipitation IntAct
SMARCB1 BRD7 24234451 30108113 association pull down,proximity-dependent biotin identification IntAct
DENND4A BRD7 19111069 27898060 inhibition N/A OmniPath

Visualization










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