Gene Information gene info

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GENE：HDDC3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HDDC3
FullNmae HD domain containing 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30522
EnsembleID ENSG00000184508
Uniprot Q8N4P3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HDDC3 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HDDC3 GO:0005515,GO:0008893,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HDDC3 hsa:374659 path:hsa00230 Purine metabolism - Homo sapiens (human)
HDDC3 hsa:374659 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP HDDC3 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 HDDC3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 HDDC3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP73 HDDC3 19558638 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 HDDC3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 HDDC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HDDC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 HDDC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HDDC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 HDDC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122F23 HDDC3 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EXOC5 HDDC3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NMI HDDC3 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
CCDC172 HDDC3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TNIP1 HDDC3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TPM3 HDDC3 25348397 N/A physical interaction ComPPI
GKAP1 HDDC3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HDDC3 APP 25348397 N/A physical interaction ComPPI
HDDC3 CEP57L1 25348397 N/A physical interaction ComPPI
HDDC3 WRAP73 25348397 N/A physical interaction ComPPI
HDDC3 GDPGP1 25348397 N/A physical interaction ComPPI
HDDC3 GOLGA8F 24234451 25348397 25416956 physical association two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HDDC3 GOLGA8DP 24234451 25348397 25416956 physical association two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ATP6V1C1 HDDC3 25348397 N/A physical interaction ComPPI

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