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GENE：MDM2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MDM2
FullNmae MDM2 proto-oncogene
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6973
EnsembleID ENSG00000135679
Uniprot Q00987

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MDM2 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MDM2 necroptosis 36279969 We also detected activation of intracellular mediators of necroptosis: IRE1, ATF6, GADD34, ERO1, Mdm2 and P53. retulator signature
MDM2 mitotic_cd 23749457 Together, MDM2-mediated mitotic catastrophe is a previously unrecognized variant of podocyte loss where MDM2 forces podocytes to complete the cell cycle, which in the absence of cytokinesis leads to podocyte aneuploidy, mitotic catastrophe, and loss by detachment.  retulator signature
MDM2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MDM2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MDM2 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
MDM2 GO:0000122,GO:0000209,GO:0001568,GO:0001974,GO:0002027,GO:0002039,GO:0002039,GO:0003181,GO:0003203,GO:0003281,GO:0003283,GO:0004842,GO:0004842,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005730,GO:0005730,GO:0005737,GO:0005737,GO:0005829,GO:0005886,GO:0006511,GO:0006511,GO:0006511,GO:0006915,GO:0006977,GO:0007049,GO:0007089,GO:0008097,GO:0008270,GO:0008284,GO:0009410,GO:0009636,GO:0010039,GO:0010468,GO:0010628,GO:0010955,GO:0010977,GO:0016567,GO:0016567,GO:0016604,GO:0016874,GO:0016925,GO:0017053,GO:0019789,GO:0019899,GO:0019904,GO:0030666,GO:0031625,GO:0031648,GO:0031648,GO:0032026,GO:0032436,GO:0032991,GO:0032991,GO:0033612,GO:0034504,GO:0042176,GO:0042220,GO:0042802,GO:0042975,GO:0043021,GO:0043066,GO:0043130,GO:0043161,GO:0043518,GO:0045184,GO:0045472,GO:0045892,GO:0045892,GO:0045931,GO:0046677,GO:0046827,GO:0048545,GO:0051149,GO:0051603,GO:0051726,GO:0051865,GO:0060411,GO:0061630,GO:0061630,GO:0061630,GO:0061630,GO:0061663,GO:0065003,GO:0070301,GO:0071301,GO:0071312,GO:0071363,GO:0071375,GO:0071391,GO:0071456,GO:0071480,GO:0071494,GO:0072537,GO:0072717,GO:0097718,GO:1901797,GO:1901797,GO:1902254,GO:1904404,GO:1904707,GO:1904754,GO:1990000,GO:1990785

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MDM2 hsa:4193 path:hsa01522 Endocrine resistance - Homo sapiens (human)
MDM2 hsa:4193 path:hsa01524 Platinum drug resistance - Homo sapiens (human)
MDM2 hsa:4193 path:hsa04068 FoxO signaling pathway - Homo sapiens (human)
MDM2 hsa:4193 path:hsa04110 Cell cycle - Homo sapiens (human)
MDM2 hsa:4193 path:hsa04115 p53 signaling pathway - Homo sapiens (human)
MDM2 hsa:4193 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)
MDM2 hsa:4193 path:hsa04144 Endocytosis - Homo sapiens (human)
MDM2 hsa:4193 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
MDM2 hsa:4193 path:hsa04218 Cellular senescence - Homo sapiens (human)
MDM2 hsa:4193 path:hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human)
MDM2 hsa:4193 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)
MDM2 hsa:4193 path:hsa05131 Shigellosis - Homo sapiens (human)
MDM2 hsa:4193 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
MDM2 hsa:4193 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
MDM2 hsa:4193 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
MDM2 hsa:4193 path:hsa05200 Pathways in cancer - Homo sapiens (human)
MDM2 hsa:4193 path:hsa05202 Transcriptional misregulation in cancer - Homo sapiens (human)
MDM2 hsa:4193 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)
MDM2 hsa:4193 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
MDM2 hsa:4193 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)
MDM2 hsa:4193 path:hsa05214 Glioma - Homo sapiens (human)
MDM2 hsa:4193 path:hsa05215 Prostate cancer - Homo sapiens (human)
MDM2 hsa:4193 path:hsa05218 Melanoma - Homo sapiens (human)
MDM2 hsa:4193 path:hsa05219 Bladder cancer - Homo sapiens (human)
MDM2 hsa:4193 path:hsa05220 Chronic myeloid leukemia - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SNAI2 MDM2 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 26192618 6396087 9450543 9618481 interaction type N/A ACSN
AKT1 MDM2 11154281 11504915 11715018 11923280 15169778 17680028 20214616 20398329 23180781 26192618 interaction type,phosphorylation reaction in-gel kinase assay,protein kinase assay ACSN,InnateDB
ATM MDM2 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 26192618 9168117 9858600 interaction type N/A ACSN
TWIST1 MDM2 11283614 11528470 12490555 13130303 14623871 15140942 15574337 15640618 15980428 16510505 16716598 16831886 17055429 17093497 17332325 17537911 17550342 17987801 18297062 18832382 19208835 19284610 19336515 20027199 20713526 20731704 20818389 21199805 21317430 21502402 21733352 2191300 21919891 22406545 22945800 26192618 7768934 9278421 interaction type N/A ACSN
HDAC1 MDM2 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 26192618 6396087 9450543 9618481 interaction type N/A ACSN
HDAC3 MDM2 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 26192618 6396087 9450543 9618481 interaction type N/A ACSN
ATR MDM2 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 26192618 9488723 9858600 interaction type N/A ACSN
MDM2 FOXO3 11715018 11779693 11923280 14761977 15024084 15084260 15169778 15876864 16307918 17110379 17158541 19321440 20679392 26192618 9450543 interaction type N/A ACSN
TP53 MDM2 10706102 15155458 15469934 19042971 19901969 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF2 MDM2 19032150 23180781 ubiquitination reaction,physical association anti tag coimmunoprecipitation,enzymatic study,solid phase assay InnateDB
EP300 MDM2 15286281 23180781 physical association anti tag coimmunoprecipitation InnateDB
HIF1A MDM2 17234751 23180781 physical association anti tag coimmunoprecipitation InnateDB
EGR1 MDM2 15225550 23180781 physical association anti tag coimmunoprecipitation InnateDB
HNRNPK MDM2 23092970 23180781 physical association anti tag coimmunoprecipitation InnateDB
RELA MDM2 15155458 23180781 physical association anti tag coimmunoprecipitation InnateDB
TBP MDM2 15155458 23180781 physical association anti tag coimmunoprecipitation InnateDB
MDM2 AATF 17468107 23180781 physical association anti tag coimmunoprecipitation InnateDB
ARRB1 MDM2 11588219 12538596 15878855 17303558 18544533 23331499 inhibition,stimulation N/A SignaLink
MDM2 IGF1R 12821780 17303558 18632619 19165858 23331499 stimulation N/A SignaLink
ABL1 MDM2 12110584 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 MDM2 11424091 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 MDM2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC MDM2 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYCN MDM2 15644444 15927364 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP53 MDM2 10469568 10566557 10718212 11756653 12851404 12902982 14532965 15851483 15856024 18566224 18583933 18971253 20036872 20837136 22180176 22223137 22532570 9071998 9645455 9858609 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 MDM2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MDM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MDM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MDM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MDM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MDM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MDM2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
BRCA1 MDM2 11256609 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MDM2 20837136 trascriptional regulation,stimulation inferred by curator TFlink
ELF4 MDM2 23393136 trascriptional regulation,stimulation inferred by curator TFlink
ELL MDM2 15851483 trascriptional regulation,stimulation inferred by curator TFlink
EP300 MDM2 11591713 trascriptional regulation,stimulation inferred by curator TFlink
ESR1 MDM2 12897156 trascriptional regulation,stimulation inferred by curator TFlink
ETS2 MDM2 12750288 trascriptional regulation,stimulation inferred by curator TFlink
FOSL2 MDM2 22493372 trascriptional regulation,stimulation inferred by curator TFlink
FUS MDM2 17234782 trascriptional regulation,stimulation inferred by curator TFlink
JUND MDM2 18071306 22493372 trascriptional regulation,stimulation inferred by curator TFlink
MLLT10 MDM2 15851483 trascriptional regulation,stimulation inferred by curator TFlink
MLLT3 MDM2 15851483 trascriptional regulation,stimulation inferred by curator TFlink
NFATC2 MDM2 22787160 trascriptional regulation,stimulation inferred by curator TFlink
NPM1 MDM2 23393136 trascriptional regulation,stimulation inferred by curator TFlink
NR4A1 MDM2 17139261 trascriptional regulation,stimulation inferred by curator TFlink
SKI MDM2 22411991 trascriptional regulation,stimulation inferred by curator TFlink
SP1 MDM2 15550242 17214373 17634539 18026875 23584477 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 MDM2 15550242 17214373 17634539 18026875 23584477 trascriptional regulation,stimulation inferred by curator TFlink
TFAP4 MDM2 19505873 trascriptional regulation,stimulation inferred by curator TFlink
TP73 MDM2 10469568 trascriptional regulation,stimulation inferred by curator TFlink
ZBTB2 MDM2 19380588 trascriptional regulation,stimulation inferred by curator TFlink
JUN MDM2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000008A99 MDM2 22330136 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00004F4657 MDM2 22330136 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000A057E MDM2 23365201 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000C85B2 MDM2 22431589 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00002FC5B0 MDM2 22431589 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00005CC20C MDM2 20542001 rna interference,inhibition western blot,quantitative reverse transcription pcr miRSponge
URS000075ABF4 MDM2 21217645 rna interference,inhibition experimental interaction detection,western blot miRSponge
URS00002FC5B0 MDM2 22431589 23592263 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00000C85B2 MDM2 22431589 23592263 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000008A99 MDM2 22330136 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00004F4657 MDM2 22330136 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000A057E MDM2 23365201 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000075ABF4 MDM2 21217645 25416803 mrna cleavage,inhibition experimental interaction detection,western blot TarBase
URS00005CC20C MDM2 20542001 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS000003ABC4 MDM2 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00005651EE MDM2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002233F4 MDM2 25136862 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00002075FA MDM2 20371350 23391506 23446348 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,clip,miRNA interference luciferase reporter assay TarBase
URS0000170CF4 MDM2 20371350 21572407 23446348 23592263 24324033 24398324 25416803 26701625 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000039A052 MDM2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 MDM2 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000045147B MDM2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 MDM2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F MDM2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F MDM2 23592263 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00002D2333 MDM2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B59A2 MDM2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B7E30 MDM2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002AAD6B MDM2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000033EBB8 MDM2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C48FA MDM2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000007A060 MDM2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 MDM2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004AF715 MDM2 20371350 21572407 23446348 23592263 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000153377 MDM2 20371350 21572407 23446348 23592263 24398324 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D860 MDM2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003D8730 MDM2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000105D19 MDM2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 MDM2 20371350 21572407 22012620 23446348 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE MDM2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E MDM2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 MDM2 20371350 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC MDM2 20371350 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B MDM2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 MDM2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 MDM2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 MDM2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F MDM2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 MDM2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 MDM2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B MDM2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A3D MDM2 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000076995 MDM2 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001B9F58 MDM2 21572407 22012620 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000015F70F MDM2 19536157 22012620 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000171FEC MDM2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 MDM2 22012620 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000184017 MDM2 22012620 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002E0524 MDM2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000042B108 MDM2 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001B0D1E MDM2 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00006097A6 MDM2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA MDM2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000003BF62 MDM2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000202460 MDM2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000272039 MDM2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000024B619 MDM2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004F859B MDM2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B MDM2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000C7662 MDM2 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000034979B MDM2 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003CC709 MDM2 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001D6605 MDM2 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000004203C MDM2 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000039D790 MDM2 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000040EC3B MDM2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000171525 MDM2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000ECE9C MDM2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002C28B2 MDM2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001C04A2 MDM2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000016E46F MDM2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 MDM2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002F8148 MDM2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 MDM2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001FFA8C MDM2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004818BD MDM2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000007340 MDM2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 MDM2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 MDM2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 MDM2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00004977C5 MDM2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC MDM2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA MDM2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000048BA36 MDM2 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D MDM2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 MDM2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C MDM2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003D4175 MDM2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000003FD55 MDM2 24882579 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000007FBA MDM2 25416803 26718483 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000100748 MDM2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C770D MDM2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002152A8 MDM2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075A760 MDM2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000078918 MDM2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000076E54 MDM2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002B0B46 MDM2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 MDM2 22135298 phosphorylation N/A PhosphoSite
MAPKAPK2 MDM2 22135298 phosphorylation N/A PhosphoSite
CSNK1D MDM2 22135298 phosphorylation N/A PhosphoSite
SRC MDM2 22135298 phosphorylation N/A PhosphoSite
ABL1 MDM2 22135298 phosphorylation N/A PhosphoSite
PLK1 MDM2 22135298 phosphorylation N/A PhosphoSite
PKM MDM2 22135298 phosphorylation N/A PhosphoSite
ATR MDM2 22135298 phosphorylation N/A PhosphoSite
PAK6 MDM2 22135298 phosphorylation N/A PhosphoSite
ATM MDM2 22135298 phosphorylation N/A PhosphoSite
PIM1 MDM2 22135298 phosphorylation N/A PhosphoSite
DAPK3 MDM2 22135298 phosphorylation N/A PhosphoSite
AKT1 MDM2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
HNRNPK MDM2 19249676 23092970 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2I MDM2 25348397 N/A physical interaction ComPPI
SMARCE1 MDM2 25348397 N/A physical interaction ComPPI
DAXX MDM2 15364927 16845383 18566590 18583933 20195357 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,display technology,fluorescence technology,nuclear magnetic resonance,pull down,physical interaction,fluorescence microscopy,in vitro,in vivo ComPPI,IntAct
PIM2 MDM2 19166854 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
TSNAX MDM2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
HSPA8 MDM2 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
BHLHE40 MDM2 17347673 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
TFRC MDM2 25348397 N/A physical interaction ComPPI
PPIB MDM2 25348397 N/A physical interaction ComPPI
MYDGF MDM2 25348397 N/A physical interaction ComPPI
RPS7 MDM2 17310983 21988832 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
KRT2 MDM2 25348397 N/A physical interaction ComPPI
S100B MDM2 20591429 24234451 25348397 N/A molecular sieving,surface plasmon resonance,physical interaction ComPPI,IntAct
S100A4 MDM2 20591429 24234451 25348397 physical association molecular sieving,surface plasmon resonance,physical interaction,competition binding ComPPI,IntAct
NPM1 MDM2 14525934 15144954 22510990 23039052 24234451 25348397 27898060 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
RARA MDM2 25348397 26776160 27898060 N/A anti bait coimmunoprecipitation,physical interaction ComPPI,OmniPath
PCNA MDM2 16861890 20733054 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CDKN1A MDM2 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
PSMC3 MDM2 25348397 N/A physical interaction ComPPI
PSMC6 MDM2 25348397 N/A physical interaction ComPPI
ATF4 MDM2 21988832 24234451 25348397 colocalization,physical association two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
SNAI2 MDM2 25348397 N/A physical interaction ComPPI
S100A1 MDM2 20591429 24234451 25348397 N/A molecular sieving,surface plasmon resonance,physical interaction ComPPI,IntAct
CCND1 MDM2 25348397 N/A physical interaction ComPPI
S100A2 MDM2 20591429 24234451 25348397 N/A molecular sieving,surface plasmon resonance,physical interaction ComPPI,IntAct
TUBB MDM2 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
MAGEA2 MDM2 25348397 N/A physical interaction ComPPI
RPL37A MDM2 25348397 N/A physical interaction ComPPI
SET MDM2 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
KPNA1 MDM2 25348397 N/A physical interaction ComPPI
VCP MDM2 25348397 N/A physical interaction ComPPI
GSTP1 MDM2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RPL11 MDM2 12842086 14525934 14612427 17110929 17310983 17373842 19713960 21399665 21988832 23507139 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
ACTB MDM2 25348397 N/A physical interaction ComPPI
RPS15 MDM2 25348397 N/A physical interaction ComPPI
RPS26 MDM2 25348397 N/A physical interaction ComPPI
FKBP1A MDM2 25348397 N/A physical interaction ComPPI
XIAP MDM2 25348397 N/A physical interaction ComPPI
RYBP MDM2 19098711 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
MKRN3 MDM2 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2D1 MDM2 25348397 N/A physical interaction ComPPI
RASSF5 MDM2 22173032 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
H2BC4 MDM2 25348397 N/A physical interaction ComPPI
SNAI1 MDM2 20385133 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSP90AB1 MDM2 25348397 N/A physical interaction ComPPI
DDX17 MDM2 25348397 N/A physical interaction ComPPI
UBE2E2 MDM2 25348397 N/A physical interaction ComPPI
CDK5RAP3 MDM2 25348397 N/A physical interaction ComPPI
CSNK1D MDM2 20708156 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,fluorescence microscopy ComPPI,IntAct
UBE2E3 MDM2 25348397 N/A physical interaction ComPPI
GNL3L MDM2 21132010 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,confocal microscopy ComPPI,IntAct
NLK MDM2 25348397 N/A physical interaction ComPPI
RPL10A MDM2 25348397 N/A physical interaction ComPPI
DLG4 MDM2 23260144 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
EZH2 MDM2 25348397 N/A physical interaction ComPPI
ERBB4 MDM2 25348397 N/A physical interaction ComPPI
SP1 MDM2 25348397 N/A physical interaction ComPPI
TBP MDM2 14525934 24234451 25348397 9271120 9388200 physical association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SRC MDM2 25348397 N/A physical interaction ComPPI
NOTCH4 MDM2 25348397 N/A physical interaction ComPPI
FBXW7 MDM2 25348397 N/A pull down ComPPI
NOTCH1 MDM2 25348397 N/A physical interaction ComPPI
PIM1 MDM2 19166854 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
SND1 MDM2 25348397 N/A physical interaction ComPPI
RAB8A MDM2 25348397 N/A physical interaction ComPPI
VEGFA MDM2 25348397 N/A physical interaction ComPPI
SETDB1 MDM2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TTF1 MDM2 22383580 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CASP3 MDM2 14525934 21726810 24234451 25241761 25348397 9278461 protein cleavage,physical association experimental interaction detection,physical interaction,protease assay,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
JUN MDM2 20195357 24234451 25348397 physical association display technology,physical interaction,tandem affinity purification ComPPI,IntAct
RB1 MDM2 14525934 16374512 20871633 24234451 25348397 7791904 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
TAF1 MDM2 14525934 25348397 9388200 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
AR MDM2 12145204 14525934 18332867 24234451 25348397 physical association affinity chromatography technology,anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
CREBBP MDM2 14525934 15013777 21149449 22349818 25348397 27898060 9809062 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
NACA MDM2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
VDR MDM2 25348397 N/A physical interaction ComPPI
SUMO1 MDM2 11384992 12393906 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EP300 MDM2 14525934 25348397 9809062 N/A experimental interaction detection,molecular sieving,physical interaction,in vitro ComPPI,HPRD
TSC22D3 MDM2 25348397 N/A physical interaction ComPPI
DHX9 MDM2 25348397 N/A physical interaction ComPPI
ATF3 MDM2 15933712 20592017 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HIF1A MDM2 10640274 12606552 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
COPS5 MDM2 14525934 17879958 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
COP1 MDM2 25348397 N/A physical interaction ComPPI
USP7 MDM2 14525934 15916963 16402859 16474402 16845383 17936559 18566590 22056774 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,classical fluorescence spectroscopy,experimental interaction detection,isothermal titration calorimetry,molecular sieving,pull down,x-ray crystallography,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PIAS1 MDM2 12393906 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
FHL2 MDM2 25348397 N/A physical interaction ComPPI
RBBP6 MDM2 17470788 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SF3B1 MDM2 25348397 N/A physical interaction ComPPI
JUND MDM2 20195357 24234451 25348397 physical association display technology,physical interaction,tandem affinity purification ComPPI,IntAct
CTBP1 MDM2 25348397 N/A physical interaction ComPPI
CTBP2 MDM2 12867035 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
KAT2B MDM2 12068014 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SFPQ MDM2 25348397 N/A physical interaction ComPPI
UBE2D2 MDM2 20705607 24234451 25348397 N/A molecular sieving,physical interaction ComPPI,IntAct
UBE2G2 MDM2 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2L3 MDM2 25348397 N/A physical interaction ComPPI
PSMA3 MDM2 22659184 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RHOA MDM2 25348397 N/A physical interaction ComPPI
U2AF2 MDM2 25348397 N/A physical interaction ComPPI
FEZ1 MDM2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
WT1 MDM2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RYR2 MDM2 20195357 24234451 25348397 physical association display technology,physical interaction,tandem affinity purification ComPPI,IntAct
GTF2I MDM2 25348397 N/A physical interaction ComPPI
GSK3B MDM2 25348397 N/A physical interaction ComPPI
CLU MDM2 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
PDIA3 MDM2 25348397 N/A physical interaction ComPPI
MED1 MDM2 14525934 15848166 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
GAPDH MDM2 25348397 N/A physical interaction ComPPI
YWHAZ MDM2 25348397 N/A physical interaction ComPPI
MAP4K4 MDM2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
CDKN2A MDM2 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
UBTF MDM2 25348397 N/A physical interaction ComPPI
UBB MDM2 14525934 17290220 17936559 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,comigration in sds page,two hybrid ComPPI,HPRD,IntAct
UBC MDM2 17290220 18566590 19098711 19166840 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,comigration in sds page ComPPI,IntAct
RPS27A MDM2 21988832 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction,comigration in sds page ComPPI,IntAct
UBA52 MDM2 25348397 N/A anti bait coimmunoprecipitation,physical interaction,comigration in sds page ComPPI
HSP90AA1 MDM2 25348397 N/A physical interaction ComPPI
UBE2N MDM2 25348397 N/A physical interaction ComPPI
USO1 MDM2 25348397 N/A physical interaction ComPPI
CANX MDM2 25348397 N/A physical interaction ComPPI
HIPK1 MDM2 22173032 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
CDH1 MDM2 16980628 25086032 25348397 27898060 N/A physical interaction ComPPI,OmniPath
BTRC MDM2 20708156 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
JAK1 MDM2 25348397 N/A physical interaction ComPPI
PDGFB MDM2 25348397 N/A physical interaction ComPPI
NUMB MDM2 12646252 14525934 18172499 24234451 25348397 9632782 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
SREK1 MDM2 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
CSNK1E MDM2 20708156 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down ComPPI,IntAct
CLSTN1 MDM2 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
E2F1 MDM2 25348397 N/A physical interaction ComPPI
SMARCA4 MDM2 25348397 N/A physical interaction ComPPI
POLH MDM2 25348397 N/A physical interaction ComPPI
POLE MDM2 10982879 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,OmniPath
HSP90B1 MDM2 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
PLK1 MDM2 19833129 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,pull down,physical interaction,protein kinase assay ComPPI,IntAct
PSMA6 MDM2 22659184 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PPP1CA MDM2 25348397 N/A physical interaction ComPPI
HEY1 MDM2 25348397 N/A physical interaction ComPPI
HNRNPU MDM2 25348397 N/A physical interaction ComPPI
MAP2 MDM2 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
NEFM MDM2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
CSNK2A1 MDM2 25348397 N/A physical interaction ComPPI
XRCC6 MDM2 25348397 N/A physical interaction ComPPI
EEF1A1 MDM2 17373842 23260144 24234451 25348397 association,physical association anti bait coimmunoprecipitation,pull down,physical interaction,confocal microscopy ComPPI,IntAct
PPARG MDM2 25348397 N/A physical interaction ComPPI
IER3 MDM2 25348397 N/A physical interaction ComPPI
TPR MDM2 25348397 N/A physical interaction ComPPI
DDX5 MDM2 25348397 N/A physical interaction ComPPI
TERT MDM2 25348397 N/A physical interaction ComPPI
PA2G4 MDM2 25348397 N/A physical interaction ComPPI
PDLIM7 MDM2 25348397 N/A physical interaction ComPPI
PPP2R5C MDM2 21460856 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDE4D MDM2 25348397 N/A physical interaction ComPPI
TP73 MDM2 10207051 10435614 11223036 14525934 19218448 24234451 25348397 N/A classical fluorescence spectroscopy,coimmunoprecipitation,experimental interaction detection,nuclear magnetic resonance,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
DAPK3 MDM2 25348397 N/A physical interaction ComPPI
RELA MDM2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PSMD1 MDM2 25348397 N/A physical interaction ComPPI
PKM MDM2 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
SORBS2 MDM2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2B MDM2 25348397 N/A physical interaction ComPPI
ANG MDM2 25348397 N/A physical interaction ComPPI
PPARD MDM2 25348397 N/A physical interaction ComPPI
RARS1 MDM2 25348397 N/A physical interaction ComPPI
RAD54B MDM2 25348397 N/A physical interaction ComPPI
ATM MDM2 11331603 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RANBP1 MDM2 25348397 N/A physical interaction ComPPI
H2BC21 MDM2 25348397 N/A physical interaction ComPPI
XPO1 MDM2 25348397 N/A physical interaction ComPPI
YWHAQ MDM2 25348397 N/A physical interaction ComPPI
SUV39H1 MDM2 25348397 N/A physical interaction ComPPI
PRDM2 MDM2 25348397 N/A physical interaction ComPPI
MDM4 MDM2 10218570 10608892 12393902 12483531 14525934 15604276 17159902 18566590 21988832 22493164 22902369 24234451 25348397 colocalization,association,physical association affinity chromatography technology,anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,two hybrid array,imaging technique,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
RBBP8 MDM2 25348397 N/A physical interaction ComPPI
EID1 MDM2 11073989 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
AATF MDM2 25348397 N/A physical interaction ComPPI
PSMC5 MDM2 25348397 N/A physical interaction ComPPI
NR0B2 MDM2 22197810 22575647 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
ARRB1 MDM2 19879840 21857681 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RNF8 MDM2 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GRK2 MDM2 14525934 17006543 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
CLPB MDM2 25348397 N/A physical interaction ComPPI
RLIM MDM2 25348397 N/A physical interaction ComPPI
RRM1 MDM2 25348397 N/A physical interaction ComPPI
RRM2B MDM2 19015526 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS6 MDM2 25348397 N/A physical interaction ComPPI
RPS6KB1 MDM2 25348397 N/A physical interaction ComPPI
RPS25 MDM2 25348397 N/A physical interaction ComPPI
HUWE1 MDM2 25348397 N/A physical interaction ComPPI
RAD23A MDM2 25348397 N/A physical interaction ComPPI
EPS15 MDM2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RPL4 MDM2 25348397 N/A physical interaction ComPPI
TRIM23 MDM2 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CUL4B MDM2 25348397 N/A physical interaction ComPPI
TBRG1 MDM2 25348397 N/A physical interaction ComPPI
STX1A MDM2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SRP19 MDM2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
IPO7 MDM2 25348397 N/A physical interaction ComPPI
ARRB2 MDM2 11588219 12488444 12538596 14525934 15878855 17984062 18544533 21081496 21389118 21466165 21988832 24234451 25348397 26545496 27898060 ubiquitination reaction,physical association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,two hybrid array,in vivo ComPPI,HPRD,IntAct,OmniPath
CSNK2A2 MDM2 25348397 N/A physical interaction ComPPI
MDM2 PML 12759344 12915590 14507915 14525934 15195100 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,imaging technique,in vitro,in vivo ComPPI,HPRD,IntAct
MDM2 KAT5 11927554 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MDM2 UBE2A 12640129 14525934 25348397 N/A coimmunoprecipitation,experimental interaction detection,physical interaction,fluorescence microscopy,in vivo ComPPI,HPRD
MDM2 NR3C1 11562347 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MDM2 TCAP 14525934 16678796 23414517 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid fragment pooling approach,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
MDM2 PSMD10 14525934 16023600 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MDM2 USP2 14525934 17290220 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
MDM2 UBQLN4 14525934 17290220 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
MDM2 HIPK2 14525934 16212962 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
MDM2 JMY 17170761 24234451 25348397 physical association anti bait coimmunoprecipitation,in vivo ComPPI,IntAct
MDM2 CHEK2 14525934 15862297 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
MDM2 DHFR 14525934 18451149 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
MDM2 PSME3 14525934 18309296 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,molecular sieving,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
MDM2 CCAR1 14525934 18382127 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MDM2 RASSF1 14525934 18566590 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
MDM2 PPM1D 14525934 17936559 24234451 25348397 dephosphorylation reaction,physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,phosphatase assay,in vitro,in vivo ComPPI,HPRD,IntAct
MDM2 ESR1 10766163 11178989 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
MDM2 AKT1 11504915 12145204 14525934 15527798 19166854 20856200 23397142 24234451 25241761 25348397 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,protein kinase assay,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
MDM2 GTF2E2 14525934 25348397 9271120 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MDM2 PJA1 10722742 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MDM2 RANBP2 12393906 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MDM2 TSG101 11172000 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MDM2 CCNG1 12556559 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MDM2 RPL5 14525934 14612427 15308643 15314173 15314174 17110929 17116689 17242401 17373842 18426907 18560357 20547751 20554519 21097889 21399665 21925390 23169665 24234451 25348397 27898060 7935455 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct,OmniPath
MDM2 MTBP 10906133 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MDM2 TP53 10196247 11178989 12842086 12867035 12915590 14525934 14704432 15144954 15604276 15848166 16212962 16432196 16845383 17080083 17139261 17159902 17268548 17310983 17347673 17438265 17470788 17875722 17879958 17936559 18172499 18309296 18316739 18451149 18485870 18815136 19098711 19166840 19234109 19255450 19411066 19656744 20173098 20591429 20708156 21132010 21170087 21726810 21857681 21988832 22085928 22510990 22575647 22653443 22659184 22819825 22975381 23776060 24207125 24234451 24667498 25241761 25348397 29997244 7686617 8875929 9278461 ubiquitination reaction,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,bioluminescence resonance energy transfer,classical fluorescence spectroscopy,two hybrid,coimmunoprecipitation,cosedimentation in solution,experimental interaction detection,fluorescence polarization spectroscopy,isothermal titration calorimetry,molecular sieving,nuclear magnetic resonance,peptide array,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,biochemical,chromatin immunoprecipitation assay,enzyme linked immunosorbent assay,genetic,luminescence based mammalian interactome mapping,proximity ligation assay,surface plasmon resonance array,ubiquitinase assay,two hybrid ComPPI,HPRD,IntAct
MDM2 MDC1 14578343 18471438 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MDM2 CDKN2A 12740913 17909018 18583933 19166854 20713054 24234451 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,fluorescence microscopy ComPPI,IntAct
MDM2 HDAC1 12426395 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
MDM2 ABL1 12110584 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
MDM2 FKBP3 19166840 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
MDM2 RPL26 18951086 20542919 21988832 23169665 24234451 25348397 27898060 physical association two hybrid,physical interaction ComPPI,IntAct,OmniPath
MDM2 GNAS 25348397 N/A physical interaction ComPPI
MDM2 GNAS 25348397 N/A physical interaction ComPPI
MDM2 GNAS 25348397 N/A physical interaction ComPPI
MDM2 FOXO4 18665269 20874444 21525355 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MDM2 GNL3 21132010 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MDM2 PTK2 25348397 N/A physical interaction ComPPI
MDM2 SFN 17546054 24234451 25348397 association coimmunoprecipitation,physical interaction ComPPI,IntAct
MDM2 NCL 20195357 22103682 24234451 25348397 physical association display technology,far western blotting,pull down,physical interaction ComPPI,IntAct
MDM2 UBE2U 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MDM2 UBE2Z 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MDM2 PYHIN1 16479015 25348397 26186194 27898060 N/A physical interaction ComPPI,OmniPath
MDM2 BANP 25348397 N/A physical interaction ComPPI
MDM2 TRIM28 25348397 N/A physical interaction ComPPI
MDM2 GATA3 25348397 N/A physical interaction ComPPI
MDM2 YY1 22659184 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MDM2 H3-4 25348397 N/A physical interaction ComPPI
MDM2 EHMT1 25348397 N/A physical interaction ComPPI
MDM2 RPS27L 21170087 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,confocal microscopy ComPPI,IntAct
MDM2 RPS27 21170087 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
MDM2 ADRB2 25348397 N/A physical interaction ComPPI
MDM2 SIVA1 25348397 N/A physical interaction ComPPI
MDM2 MTA1 25348397 N/A physical interaction ComPPI
MDM2 RCHY1 19483087 20333547 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MDM2 G3BP2 25348397 N/A physical interaction ComPPI
MDM2 PSMD2 25348397 N/A physical interaction ComPPI
MDM2 PAK1IP1 25348397 N/A physical interaction ComPPI
MDM2 ZNF668 25348397 N/A physical interaction ComPPI
MDM2 TP63 25348397 N/A physical interaction ComPPI
MDM2 USP10 25348397 N/A physical interaction ComPPI
MDM2 PSMC1 25348397 N/A physical interaction ComPPI
MDM2 PSMD4 25348397 N/A physical interaction ComPPI
MDM2 PSMA7 25348397 N/A physical interaction ComPPI
MDM2 RUNX3 25348397 N/A physical interaction ComPPI
MDM2 APEX1 25348397 N/A physical interaction ComPPI
MDM2 UIMC1 25348397 N/A physical interaction ComPPI
MDM2 SOX4 25348397 N/A physical interaction ComPPI
MDM2 UBE4B 25348397 N/A physical interaction ComPPI
MDM2 BAIAP2L1 25348397 N/A physical interaction ComPPI
MDM2 RFWD3 20173098 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
MDM2 ERBB3 25348397 N/A physical interaction ComPPI
MDM2 HEXIM1 25348397 N/A physical interaction ComPPI
MDM2 CDK9 25348397 N/A physical interaction ComPPI
MDM2 DYRK2 25348397 N/A physical interaction ComPPI
MDM2 HSP90AA2P 25348397 N/A physical interaction ComPPI
MDM2 HSPA4 25348397 N/A physical interaction ComPPI
MDM2 LAMP2 25348397 N/A physical interaction ComPPI
MDM2 RPS3 19656744 24234451 25348397 ubiquitination reaction,association,physical association anti bait coimmunoprecipitation,fluorescent resonance energy transfer,pull down,physical interaction,proximity ligation assay,ubiquitinase assay ComPPI,IntAct
MDM2 TRIM13 25348397 N/A physical interaction ComPPI
MDM2 GORAB 20598683 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
MDM2 FOXO1 25348397 N/A physical interaction ComPPI
MDM2 FOXO3 25348397 N/A physical interaction ComPPI
MDM2 UCHL1 25348397 N/A physical interaction ComPPI
MDM2 USP42 25348397 N/A physical interaction ComPPI
MDM2 CUL1 20708156 24234451 24804778 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
MDM2 FBXW11 20708156 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
MDM2 SMURF1 25348397 N/A physical interaction ComPPI
MDM2 CSNK1A1 20708156 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
MDM2 SENP3 25348397 N/A physical interaction ComPPI
MDM2 TRIM27 25348397 N/A physical interaction ComPPI
MDM2 RFFL 25348397 N/A physical interaction ComPPI
MDM2 PTPA 25348397 N/A physical interaction ComPPI
MDM2 PSMB6 22659184 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MDM2 PSMA8 25348397 N/A physical interaction ComPPI
MDM2 RASSF3 25348397 N/A physical interaction ComPPI
MDM2 LATS1 25348397 N/A physical interaction ComPPI
MDM2 RAD50 25348397 N/A physical interaction ComPPI
MDM2 NBN 25348397 N/A physical interaction ComPPI
MDM2 MRE11 25348397 N/A physical interaction ComPPI
MDM2 CUL4A 25348397 N/A physical interaction ComPPI
MDM2 DTL 25348397 N/A physical interaction ComPPI
MDM2 ESR2 25348397 N/A physical interaction ComPPI
MDM2 BUB1B 25348397 N/A physical interaction ComPPI
MDM2 IRF2 25348397 N/A physical interaction ComPPI
MDM2 TPT1 25348397 N/A physical interaction ComPPI
MDM2 PDCD5 25348397 N/A physical interaction ComPPI
MDM2 CDKN2AIP 25348397 N/A physical interaction ComPPI
MDM2 LATS2 25348397 N/A physical interaction ComPPI
MDM2 WWOX 25348397 N/A physical interaction ComPPI
MDM2 ERCC6 25348397 N/A physical interaction ComPPI
MDM2 ERCC6 25348397 N/A physical interaction ComPPI
MDM2 ERCC8 25348397 N/A physical interaction ComPPI
MDM2 DDB1 25348397 N/A physical interaction ComPPI
MDM2 DHRS2 25348397 N/A physical interaction ComPPI
MDM2 ITCH 21093410 25348397 26025930 27898060 N/A physical interaction ComPPI,OmniPath
MDM2 EEF1A1P5 25348397 N/A physical interaction ComPPI
MDM2 DCD 17373842 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MDM2 TUBB2A 25348397 N/A physical interaction ComPPI
MDM2 KRT14 17373842 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MDM2 RPS20 17373842 19656744 23874713 24234451 25348397 27898060 association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct,OmniPath
MDM2 TUBA1C 17373842 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MDM2 GSN 25348397 N/A physical interaction ComPPI
MDM2 HNF4A 25348397 N/A physical interaction ComPPI
MDM2 NME2 21504894 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MDM2 NEDD4 15001356 24413081 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MDM2 DAPK1 25348397 N/A physical interaction ComPPI
MDM2 PBX1 25348397 N/A physical interaction ComPPI
MDM2 UBE2D3 25348397 N/A physical interaction ComPPI
MDM2 UBE3A 25348397 N/A physical interaction ComPPI
MDM2 RNF2 25348397 N/A physical interaction ComPPI
MDM2 EGR1 25348397 N/A physical interaction ComPPI
MDM2 PAK6 25348397 N/A physical interaction ComPPI
MDM2 IRF1 23134341 24583282 24721577 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MDM2 CENPX 25348397 N/A physical interaction ComPPI
MDM2 GADD45A 25348397 N/A physical interaction ComPPI
MDM2 RABL6 25348397 N/A physical interaction ComPPI
MDM2 RPL37 25348397 N/A physical interaction ComPPI
MDM2 TRIM4 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MDM2 TRAF5 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MDM2 TRIM9 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MDM2 PHF7 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MDM2 RNF10 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MDM2 RNF126 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MDM2 UBE2K 25348397 N/A physical interaction ComPPI
MDM2 LMO7 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MDM2 HLA-DMB 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MDM2 YY1AP1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MDM2 NACA 25348397 N/A physical interaction ComPPI
MDM2 NACA4P 25348397 N/A physical interaction ComPPI
MDM2 MYD88 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MDM2 SDHC 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MDM2 DNAJB4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MDM2 GCAT 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MDM2 SHPK 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MDM2 POT1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MDM2 ANKRD17 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MDM2 NOP53 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MDM2 SESN2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MDM2 RASSF6 25348397 N/A physical interaction ComPPI
MDM2 EZR 20195357 24234451 25348397 physical association display technology,physical interaction,tandem affinity purification ComPPI,IntAct
MDM2 APP 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
MDM2 CWC25 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
MDM2 ZNF133 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
MDM2 TAB1 25348397 N/A physical interaction ComPPI
MDM2 RPL6 25348397 N/A physical interaction ComPPI
MDM2 AURKA 24240108 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MDM2 NOC2L 25348397 N/A physical interaction ComPPI
MDM2 XPC 25348397 N/A physical interaction ComPPI
MDM2 PGAM1 25348397 N/A physical interaction ComPPI
MDM2 PGAM2 25348397 N/A physical interaction ComPPI
MDM2 DNAJB1 25348397 N/A physical interaction ComPPI
MDM2 ANAPC2 25348397 N/A physical interaction ComPPI
MDM2 RBM38 22710720 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MDM2 ALDH16A1 25348397 N/A physical interaction ComPPI
MDM2 DLAT 25348397 N/A physical interaction ComPPI
MDM2 EDC4 25348397 N/A physical interaction ComPPI
MDM2 EIF2AK1 25348397 N/A physical interaction ComPPI
MDM2 ESYT1 25348397 N/A physical interaction ComPPI
MDM2 ARHGAP45 25348397 N/A physical interaction ComPPI
MDM2 HNRNPM 25348397 N/A physical interaction ComPPI
MDM2 HRNR 25348397 N/A physical interaction ComPPI
MDM2 IARS1 25348397 N/A physical interaction ComPPI
MDM2 IFI16 25348397 N/A physical interaction ComPPI
MDM2 IGF2BP3 25348397 N/A physical interaction ComPPI
MDM2 ILF3 25348397 N/A physical interaction ComPPI
MDM2 KARS1 25348397 N/A physical interaction ComPPI
MDM2 CCAR2 25348397 N/A physical interaction ComPPI
MDM2 NEK9 25348397 N/A physical interaction ComPPI
MDM2 OGDH 25348397 N/A physical interaction ComPPI
MDM2 OGDHL 25348397 N/A physical interaction ComPPI
MDM2 RECQL 25348397 N/A physical interaction ComPPI
MDM2 TOP1 25348397 N/A physical interaction ComPPI
MDM2 ZNF318 25348397 N/A physical interaction ComPPI
MDM2 PER2 25348397 N/A physical interaction ComPPI
MDM2 SIRT6 25348397 N/A physical interaction ComPPI
MDM2 UBE2M 25348397 N/A physical interaction ComPPI
MDM2 FSBP 25348397 N/A physical interaction ComPPI
MDM2 SMARCA2 25348397 N/A physical interaction ComPPI
MDM2 ACACA 25348397 N/A physical interaction ComPPI
MDM2 PTBP1 25348397 N/A physical interaction ComPPI
MDM2 IYD 25348397 N/A physical interaction ComPPI
MDM2 HNRNPD 25348397 N/A physical interaction ComPPI
MDM2 FUBP1 25348397 N/A physical interaction ComPPI
MDM2 EEF2 25348397 N/A physical interaction ComPPI
MDM2 EIF3B 25348397 N/A physical interaction ComPPI
MDM2 DCAF8 25348397 N/A physical interaction ComPPI
MDM2 EFTUD2 25348397 N/A physical interaction ComPPI
MDM2 EXOSC6 25348397 N/A physical interaction ComPPI
MDM2 SF3B3 25348397 N/A physical interaction ComPPI
MDM2 DET1 25348397 N/A physical interaction ComPPI
MDM2 DIRAS3 25348397 N/A physical interaction ComPPI
MDM2 SURF2 25348397 N/A physical interaction ComPPI
MDM2 RFPL2 25348397 N/A physical interaction ComPPI
MDM2 CMSS1 25348397 N/A physical interaction ComPPI
MDM2 RPL22L1 25348397 N/A physical interaction ComPPI
MDM2 IER2 25348397 N/A physical interaction ComPPI
MDM2 ZNF420 25348397 N/A physical interaction ComPPI
MDM2 ELF4 25348397 N/A physical interaction ComPPI
MDM2 ABL2 25348397 N/A physical interaction ComPPI
MDM2 HCK 25348397 N/A physical interaction ComPPI
MDM2 ATP2A2 25348397 N/A physical interaction ComPPI
MDM2 BRINP1 25348397 N/A physical interaction ComPPI
MDM2 MS4A1 25348397 N/A physical interaction ComPPI
MDM2 RPS23 25348397 N/A physical interaction ComPPI
MDM2 RUVBL2 25348397 N/A physical interaction ComPPI
MDM2 SRSF11 25348397 N/A physical interaction ComPPI
MDM2 FBXO31 25348397 N/A physical interaction ComPPI
MDM2 TFIP11 25348397 N/A physical interaction ComPPI
MDM2 SETD7 25348397 N/A physical interaction ComPPI
MDM2 DDX24 25348397 N/A physical interaction ComPPI
MDM2 NAT10 25348397 N/A physical interaction ComPPI
MDM2 RPL23A 25348397 N/A physical interaction ComPPI
MDM2 SUZ12 25348397 N/A physical interaction ComPPI
MDM2 EED 25348397 N/A physical interaction ComPPI
MDM2 NOLC1 25348397 N/A physical interaction ComPPI
MDM2 DDX42 25348397 N/A physical interaction ComPPI
MDM2 NUCKS1 20195357 24234451 25348397 physical association display technology,physical interaction ComPPI,IntAct
MDM2 RRP1 25348397 N/A physical interaction ComPPI
MDM2 PDS5A 25348397 N/A physical interaction ComPPI
MDM2 RPL36A 25348397 N/A physical interaction ComPPI
MDM2 RPL15 25348397 N/A physical interaction ComPPI
MDM2 HMGN1 25348397 N/A physical interaction ComPPI
MDM2 MAP1LC3A 25348397 N/A physical interaction ComPPI
MDM2 RESF1 25348397 N/A physical interaction ComPPI
MDM2 PBXIP1 25348397 N/A physical interaction ComPPI
MDM2 SHARPIN 25348397 N/A physical interaction ComPPI
MDM2 MAPKAPK2 25348397 N/A physical interaction ComPPI
MDM2 USP15 25348397 N/A physical interaction ComPPI
MDM2 USP26 25348397 N/A physical interaction ComPPI
MDM2 NGFR 25348397 N/A physical interaction ComPPI
MDM2 SMG7 25348397 N/A physical interaction ComPPI
MDM2 RSL1D1 25348397 N/A physical interaction ComPPI
MDM2 SIRT1 25348397 N/A physical interaction ComPPI
MDM2 SIRT7 25348397 N/A physical interaction ComPPI
MDM2 SIRT2 25348397 N/A physical interaction ComPPI
MDM2 SIRT3 25348397 N/A physical interaction ComPPI
MDM2 MSI2 25348397 N/A physical interaction ComPPI
MDM2 PHLDB3 25348397 N/A physical interaction ComPPI
MDM2 XAGE1A 25348397 N/A physical interaction ComPPI
MDM2 ZNF550 25348397 N/A physical interaction ComPPI
MDM2 YAF2 25348397 N/A physical interaction ComPPI
MDM2 ARNTL2 25348397 N/A physical interaction ComPPI
MDM2 RPS11 25348397 N/A physical interaction ComPPI
MDM2 TSPYL6 25348397 N/A physical interaction ComPPI
MDM2 H2BC11 25348397 N/A physical interaction ComPPI
MDM2 ZNF764 25348397 N/A physical interaction ComPPI
MDM2 MAK16 25348397 N/A physical interaction ComPPI
MDM2 ZNF274 25348397 N/A physical interaction ComPPI
MDM2 PPAN 25348397 N/A physical interaction ComPPI
MDM2 CRTC2 25348397 N/A physical interaction ComPPI
MDM2 CRTC3 25348397 N/A physical interaction ComPPI
MDM2 TRIM25 25348397 N/A physical interaction ComPPI
MDM2 CSNK2B 25348397 N/A physical interaction ComPPI
MDM2 USP48 25348397 N/A physical interaction ComPPI
MDM2 TP53I3 25348397 N/A physical interaction ComPPI
MDM2 ATRX 25348397 N/A physical interaction ComPPI
MDM2 BCAR1 25348397 N/A physical interaction ComPPI
MDM2 TUBB1 17373842 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MDM2 CDKN2B 17373842 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MDM2 GAPDHS 17373842 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MDM2 PIM3 19166854 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
MDM2 PFDN6 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 BAIAP2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 EEF1G 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 ERICH3 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 WDR45 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 RASGRF1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 FAM171A1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 MARS1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 RCN2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 NUDT9 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 ZBTB1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 PTPRD 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 DAAM2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 KIF5A 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 RPL27A 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 ARHGEF6 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 GABRA2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 OGA 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 TBCA 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 ZNF766 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 NDUFA12 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 PRPF6 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 CHRM3 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 MEA1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 ZNHIT6 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 TMEM87A 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 SMC3 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 PRRC2C 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 SEC63 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 MRPS33 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 NSD2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 NAP1L1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 ZNF326 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
MDM2 GNL2 21132010 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
MDM2 OTUB1 22124327 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down ComPPI,IntAct
TP53RK MDM2 25348397 N/A physical interaction ComPPI
CASP2 MDM2 21726810 24234451 25348397 protein cleavage physical interaction,protease assay ComPPI,IntAct
FHIT MDM2 25348397 N/A physical interaction ComPPI
KPNA6 MDM2 25348397 N/A physical interaction ComPPI
RPL23 MDM2 17110929 17310983 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
S100A6 MDM2 20591429 24234451 25348397 N/A molecular sieving,surface plasmon resonance,physical interaction ComPPI,IntAct
AGPS MDM2 25348397 N/A physical interaction ComPPI
IGF1R MDM2 12821780 14525934 18632619 20195357 24234451 25241761 25348397 physical association display technology,experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
ARIH2 MDM2 22819825 22940738 24234451 25348397 27898060 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
RPS14 MDM2 25348397 N/A physical interaction ComPPI
RIDA MDM2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MDM2 MDM2 17159902 17936559 22493164 24234451 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid array IntAct
MDM2 PPARA 19103650 27898060 N/A N/A OmniPath
CEBPB MDM2 25720496 27898060 N/A N/A OmniPath
PAX3 MDM2 22216266 27898060 N/A N/A OmniPath
MDM2 SLC14A2 18784257 27898060 N/A N/A OmniPath
TAT MDM2 12883554 27898060 N/A N/A OmniPath
SRC MDM2 25624478 27898060 N/A N/A OmniPath
NUMB MDM2 12646252 16678796 18172499 20940030 22337874 23252402 27898060 9632782 inhibition N/A OmniPath
MDM2 NUMB 12646252 16678796 18172499 20940030 22337874 23252402 27898060 9632782 inhibition N/A OmniPath
ARRB1 MDM2 11588219 12538596 15878855 17303558 18544533 19879840 21081496 21466165 27898060 inhibition,stimulant N/A OmniPath
PLK1 MDM2 12383858 19833129 27898060 stimulant N/A OmniPath
MAPKAPK2 MDM2 15688025 27898060 stimulant N/A OmniPath
CHEK2 MDM2 10710310 15862297 16943424 19176998 27898060 inhibition,stimulant N/A OmniPath
ELAVL1 MDM2 19884656 27898060 stimulant N/A OmniPath
MDM2 IGF1R 12821780 17303558 18632619 19165858 20195357 25241761 27898060 inhibition,stimulant N/A OmniPath
ATR MDM2 11504915 14654783 15169778 15527798 15688025 27898060 inhibition N/A OmniPath
PIM1 MDM2 11504915 11715018 11923280 11960368 18467333 19166854 23132866 27898060 stimulant N/A OmniPath
ATM MDM2 10611322 11331603 12167711 12383858 15703839 17936559 19816404 24813712 27898060 inhibition,stimulant N/A OmniPath
MDM2 TP63 11714701 20571051 21088494 25417702 27898060 inhibition,stimulant N/A OmniPath
AKT1 MDM2 11504915 11715018 11923280 12145204 15169778 15527798 18332867 19166854 19664995 20856200 21930127 23397142 25241761 27898060 stimulant N/A OmniPath
MDM2 AKT1 11504915 11715018 11923280 12145204 15169778 15527798 18332867 19166854 20856200 21930127 23397142 25241761 27898060 N/A N/A OmniPath
MDM2 KAT5 11927554 16904321 18264029 18499675 19150978 27898060 inhibition N/A OmniPath
TRIM28 MDM2 16107876 17056014 20858735 27898060 stimulant N/A OmniPath
TP53 MDM2 10196247 10321734 10347217 10435614 10488081 10561590 10562557 10608892 10640350 10681559 10706102 10722742 10766163 10827196 10889512 10980696 11046142 11070080 11094089 11112690 11178989 11223036 11278372 11285227 11328884 11331603 11351297 11384992 11431470 11486026 11562347 11572869 11597128 11697899 11709713 11713287 11713288 11714701 11744695 11839577 11925449 11983168 12167711 12208736 12381304 12426395 12529318 12552135 12612087 12620407 12690203 12842086 12867035 12897156 12915590 12944468 14499615 14517261 14559824 14596917 14612427 14671306 14702041 14704432 14741215 15001357 15013777 15053879 15058298 15064742 15094782 15122315 15144954 15154850 15155458 15210108 15242646 15247280 15280377 15295102 15308643 15313915 15469934 15542844 15558054 15604276 15824742 15838523 15848166 15908921 15933712 15950904 16023600 16055726 16107876 1614537 16152627 16159876 16173922 16212962 16215989 16330492 16331255 16338390 16414131 16432196 16547496 16579792 16595680 16624812 16678796 16751805 16845383 16857591 16861890 16866370 16870621 16905769 16964247 17056014 17060322 17080083 17098746 17116689 17139261 17159902 17268548 17290220 17297477 17301054 17302414 17318220 17347673 17363365 17369817 17380154 17426254 17438265 17470788 17525743 17591690 17616658 17666403 17848574 17875722 17879958 17908790 17936559 17989425 18061646 18172499 18223694 18234963 18309296 18316739 18332869 18451149 18467333 18485870 18541670 18566590 18604177 18665269 18813780 18815136 18981217 19033382 19071110 19081178 19085961 19098711 19106616 19153082 19160491 19166840 19188367 19223463 19234109 19255450 19303885 19305137 19332559 19357310 19411066 19411846 19483087 19568783 19579266 19590512 19597489 19656744 19805293 19816404 19837670 19857530 19901969 19941302 20047188 20080206 20124408 20173098 20174603 20234175 20235143 20395212 20479273 20484049 20542919 20570896 20588255 20591429 20591651 20624280 20639885 20657550 20659896 20694676 20705607 20708156 20847049 20959462 20962272 21060154 21071676 21075307 21084285 21084564 21088494 21098709 21132010 21149449 21170087 21261729 21268072 21316347 21317885 21454483 21465263 21471462 21478269 21561866 21572037 21584881 21726810 21750659 21857681 21887275 21925390 21965653 21986495 21988832 22032989 22046440 22083959 22084066 22085928 22103682 22124327 22157679 22227409 22262183 22266850 22266868 22301280 22318540 22331460 22366412 22374672 22389628 22391559 22405968 22411991 22444248 22474335 22487680 22525275 22575647 22588298 22659184 22737255 22807444 22819825 22912717 22914926 22916255 22920093 22948151 22975381 23134341 23150668 23169665 23201157 23246961 23252402 23261415 23318437 23370271 23402884 23443559 23483203 23572512 23609977 23671280 23728348 23776060 23776465 23802716 23826318 23880345 23946421 24127580 24200963 24207125 24240685 24314634 24361594 24413661 24567357 24621507 24643130 24659749 24667498 24842904 24926618 24980433 24998844 25103245 25156994 25168242 25241761 25277184 25283148 25313037 25362358 25384516 25417702 25464845 25512388 25543083 25609649 25624478 25637791 25739118 25912675 26001071 26186194 26238070 26350565 26540344 26556313 26578655 26673821 27898060 7686617 7689721 7926727 8058315 8875929 9131587 9223638 9260156 9271120 9278461 9363941 9450543 9529249 9582019 9724739 9809062 9824166 stimulant N/A OmniPath
MDM2 TP53 10196247 10321734 10347217 10435614 10488081 10561590 10562557 10608892 10640350 10681559 10706102 10722742 10766163 10827196 10889512 10935507 10980696 11046142 11070080 11094089 11112690 11178989 11223036 11278372 11285227 11328884 11331603 11351297 11384992 11431470 11486026 11562347 11572869 11597128 11697899 11709713 11713287 11713288 11714701 11744695 11839577 11925449 11983168 12167711 12208736 12381304 12426395 12529318 12552135 12612087 12620407 12690203 12842086 12867035 12897156 12915590 12944468 14499615 14517261 14559824 14596917 14612427 14671306 14702041 14704432 14741215 15001357 15013777 15053879 15058298 15064742 15094782 15122315 15144954 15154850 15155458 15210108 15242646 15247280 15280377 15295102 15308643 15313915 15469934 15542844 15558054 15604276 15824742 15838523 15848166 15908921 15933712 15950904 16023600 16055726 16107876 1614537 16152627 16159876 16173922 16212962 16215989 16330492 16331255 16338390 16414131 16432196 16547496 16579792 16595680 16624812 16678796 16751805 16845383 16857591 16861890 16866370 16870621 16905769 16964247 17056014 17060322 17080083 17098746 17110336 17116689 17139261 17159902 17268548 17290220 17297477 17301054 17302414 17318220 17347673 17363365 17369817 17380154 17426254 17438265 17470788 17525743 17591690 17616658 17666403 17848574 17875722 17879958 17908790 17936559 17989425 18061646 18172499 18223694 18234963 18309296 18316739 18332869 18451149 18467333 18485870 18541670 18566590 18604177 18665269 18813780 18815136 18981217 19033382 19071110 19081178 19085961 19098711 19106616 19153082 19160491 19166840 19188367 19223463 19234109 19255450 19303885 19305137 19332559 19357310 19411066 19411846 19483087 19568783 19579266 19590512 19597489 19656744 19805293 19816404 19837670 19857530 19901969 19941302 20047188 20080206 20124408 20173098 20174603 20234175 20235143 20395212 20479273 20484049 20542919 20570896 20588255 20591429 20591651 20624280 20639885 20657550 20659896 20694676 20705607 20708156 20847049 20959462 20962272 21060154 21071676 21075307 21084285 21084564 21088494 21098709 21132010 21149449 21170087 21261729 21268072 21316347 21317885 21454483 21465263 21471462 21478269 21561866 21572037 21584881 21726810 21750659 21857681 21887275 21925390 21965653 21986495 21988832 22032989 22046440 22083959 22084066 22085928 22103682 22124327 22157679 22227409 22262183 22266850 22266868 22301280 22318540 22331460 22337874 22366412 22374672 22389628 22391559 22405968 22411991 22444248 22474335 22487680 22525275 22575647 22588298 22659184 22737255 22807444 22819825 22912717 22914926 22916255 22920093 22948151 22975381 23134341 23150668 23150757 23169665 23201157 23246961 23252402 23261415 23318437 23370271 23402884 23443559 23483203 23572512 23609977 23671280 23728348 23776060 23776465 23802716 23826318 23880345 23946421 24127580 24200963 24207125 24240685 24314634 24361594 24413661 24567357 24621507 24643130 24659749 24667498 24842904 24926618 24980433 24998844 25103245 25156994 25168242 25241761 25277184 25283148 25313037 25362358 25384516 25417702 25464845 25512388 25543083 25609649 25624478 25637791 25739118 25912675 26001071 26186194 26238070 26350565 26540344 26556313 26578655 26673821 27898060 7686617 7689721 7926727 8058315 8875929 9131587 9223638 9260156 9271120 9278461 9363941 9450543 9529249 9582019 9724739 9809062 9824166 inhibition N/A OmniPath
PPM1D MDM2 17936559 17939684 27898060 inhibition,stimulant N/A OmniPath
ABL1 MDM2 12110584 14757045 16702947 20841568 21081495 25624478 27898060 inhibition,stimulant N/A OmniPath
DAXX MDM2 15364927 16845383 18566590 18583933 20195357 21134643 23038753 23405218 27898060 stimulant N/A OmniPath
MDM2 TP53BP1 14671306 27898060 inhibition N/A OmniPath
CDKN2A MDM2 10713175 10801444 10822382 10871849 11223036 11718560 12085228 12167711 12209154 14612427 15355988 15485902 16107876 16173922 16915296 17116689 17426254 17909018 18418067 18467333 18541670 18583933 18813780 19049976 19166854 20395212 20713054 20832751 21133853 22120712 23580573 24769896 25809483 27898060 9529248 9529249 9653180 9724636 inhibition N/A OmniPath
PPP1CB MDM2 23277204 27898060 stimulant N/A OmniPath
CSNK1D MDM2 12167711 15703839 16335531 16870621 19816404 20708156 21986495 21990374 22976441 27898060 inhibition N/A OmniPath
MDM2 AR 12145204 15640443 17974989 18332867 21157430 23132866 26196320 26411689 27898060 inhibition N/A OmniPath
PPP1CA MDM2 23277204 27898060 stimulant N/A OmniPath
DDX17 MDM2 17226766 27898060 stimulant N/A OmniPath
MDM2 RELA 15155458 21988832 23839035 27898060 stimulant N/A OmniPath
MDM2 EP300 11070080 15013777 15154850 15286281 20234175 27898060 9809062 inhibition N/A OmniPath
EP300 MDM2 11070080 15013777 15154850 15286281 20234175 27898060 9809062 N/A N/A OmniPath
ERBB4 MDM2 15985438 27898060 inhibition,stimulant N/A OmniPath
SGK1 MDM2 19690332 19756449 27898060 N/A N/A OmniPath
MDM2 NOTCH1 22128911 23252402 27898060 stimulant N/A OmniPath
PPP2CA MDM2 11983168 27898060 stimulant N/A OmniPath
USP7 MDM2 15916963 16082221 16402859 16474402 16845383 16943424 17380154 17936559 18566590 20697359 20713061 20816748 22056774 26238070 26460617 27898060 stimulant N/A OmniPath
MDM2 HNRNPK 16360036 19249676 22825850 23092970 27898060 inhibition N/A OmniPath
MDM2 JMY 17170761 17386256 27898060 inhibition,stimulant N/A OmniPath
COPS5 MDM2 17879958 18926707 27898060 stimulant N/A OmniPath
MDM2 RRM2B 19015526 27898060 inhibition N/A OmniPath
MDM2 TP73 10207051 10321734 10435614 10469568 11223036 17700533 18499675 19218448 20588255 21088494 21261729 25301064 25417702 26025930 27898060 inhibition N/A OmniPath
MDM2 HIF1A 10640274 12606552 17234751 19696166 25447306 27898060 stimulant N/A OmniPath
HIF1A MDM2 10640274 12606552 17234751 19696166 25447306 27898060 N/A N/A OmniPath
AKT2 MDM2 11504915 27898060 stimulant N/A OmniPath
GSK3B MDM2 16055726 18505846 27898060 stimulant N/A OmniPath
DAPK3 MDM2 12167711 15001356 23146908 27898060 stimulant N/A OmniPath
RPS6KB1 MDM2 20657550 27898060 inhibition,stimulant N/A OmniPath
MDM4 MDM2 10218570 10608892 10827196 11606419 12370303 12393902 12483531 12860999 12874296 15604276 15735705 16055726 16227609 16511560 17159902 17301054 17616658 18219319 19432880 19573810 19619542 19683495 19838211 20473904 20484049 20697359 20705607 20724842 21730132 21925390 21988832 22120712 22266850 22333590 22493164 22666487 23028042 23671280 23946421 24755078 24813712 25105592 25384516 25512388 25659040 25703327 25809483 25825738 25981963 26001071 27898060 inhibition,stimulant N/A OmniPath
MDM2 MDM4 10218570 10608892 10827196 11606419 12370303 12393902 12483531 12860999 12874296 12963717 15604276 15735705 16055726 16227609 16511560 17159902 17301054 17616658 18219319 19432880 19573810 19619542 19683495 19838211 20473904 20484049 20697359 20705607 20724842 21730132 21925390 21988832 22120712 22266850 22333590 22493164 22666487 23028042 23671280 23946421 24755078 24813712 25105592 25384516 25512388 25659040 25703327 25809483 25825738 25981963 26001071 27898060 inhibition,stimulant N/A OmniPath
PRKDC MDM2 11504915 12167711 27898060 stimulant N/A OmniPath
MDM2 GRK2 17006543 21081496 26228571 27898060 N/A N/A OmniPath
MDM2 CDKN2AIP 17460193 18292944 27898060 inhibition N/A OmniPath
PPP1CC MDM2 23277204 27898060 stimulant N/A OmniPath
MDM2 NOTCH4 21402876 27898060 inhibition N/A OmniPath
CDKN2A MDM2 12740913 17909018 18583933 19166854 20713054 23416275 27898060 inhibition N/A OmniPath
PPP2CB MDM2 11983168 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B1CA8 MDM2 27087310 direct interaction,inhibition N/A NPInter

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