GENE：RGCC
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RGCC |
| FullNmae | regulator of cell cycle |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:20369 |
| EnsembleID | ENSG00000102760 |
| Uniprot | Q9H4X1 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RGCC | parthanatos | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| RGCC | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RGCC | GO:0001100,GO:0001818,GO:0001819,GO:0001937,GO:0003331,GO:0005515,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005737,GO:0005813,GO:0005829,GO:0006956,GO:0007049,GO:0008285,GO:0010628,GO:0010718,GO:0010718,GO:0016525,GO:0019901,GO:0019901,GO:0019901,GO:0030295,GO:0030295,GO:0032967,GO:0043537,GO:0045737,GO:0045737,GO:0045840,GO:0045944,GO:0051091,GO:0051496,GO:0070412,GO:0071456,GO:0072537,GO:0090272,GO:1900087,GO:1901203,GO:1901991,GO:2000048,GO:2000353,GO:2000573 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| RGCC | hsa:28984 | path:hsa04810 | Regulation of actin cytoskeleton - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | RGCC | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | RGCC | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | RGCC | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | RGCC | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | RGCC | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | RGCC | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | RGCC | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | RGCC | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | RGCC | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | RGCC | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CDK1 | RGCC | 22135298 | phosphorylation | N/A | PhosphoSite |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SMAD2 | RGCC | 25348397 | N/A | physical interaction | ComPPI |
| SMAD3 | RGCC | 25348397 | N/A | physical interaction | ComPPI |
| TLN1 | RGCC | 25348397 | N/A | physical interaction | ComPPI |
| PLK1 | RGCC | 25348397 | N/A | physical interaction | ComPPI |
| AKT1 | RGCC | 25348397 | N/A | physical interaction | ComPPI |
| TLN2 | RGCC | 25348397 | N/A | physical interaction | ComPPI |
| RGCC | CDK1 | 11687586 14525934 25348397 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| RGCC | TRAF7 | 25348397 | N/A | physical interaction | ComPPI |
| RGCC | CARS2 | 25348397 | N/A | physical interaction | ComPPI |
| AKT1 | RGCC | 19162005 27898060 | N/A | N/A | OmniPath |
| TP53 | RGCC | 18431400 27898060 | stimulant | N/A | OmniPath |
| CDK1 | RGCC | 11687586 19162005 19690332 27898060 | N/A | N/A | OmniPath |