Gene Information gene info

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GENE：YTHDC2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol YTHDC2
FullNmae YTH N6-methyladenosine RNA binding protein C2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24721
EnsembleID ENSG00000047188
Uniprot Q9H6S0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
YTHDC2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
YTHDC2 GO:0003723,GO:0003723,GO:0004386,GO:0005515,GO:0005524,GO:0005622,GO:0005783,GO:0007286,GO:0008186,GO:0016887,GO:0034458,GO:0034612,GO:0035770,GO:0044829,GO:0048471,GO:0048599,GO:0051321,GO:0051729,GO:0070063,GO:0070555,GO:1990247

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IRAK1 YTHDC2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF4 YTHDC2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
JUN YTHDC2 23180781 24269672 physical association anti tag coimmunoprecipitation InnateDB
ATF2 YTHDC2 23180781 24269672 physical association anti tag coimmunoprecipitation InnateDB
POLR2B YTHDC2 23180781 24269672 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 YTHDC2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 YTHDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF YTHDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 YTHDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 YTHDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 YTHDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 YTHDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS YTHDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 YTHDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A YTHDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 YTHDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 YTHDC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000017EA6A YTHDC2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016FF9C YTHDC2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SNW1 YTHDC2 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CBX8 YTHDC2 21282530 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NIFK YTHDC2 25348397 N/A physical interaction ComPPI
FGF3 YTHDC2 25348397 N/A physical interaction ComPPI
JUN YTHDC2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 YTHDC2 25348397 N/A physical interaction ComPPI
RPL18A YTHDC2 25348397 N/A physical interaction ComPPI
IRF4 YTHDC2 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL3 YTHDC2 25348397 N/A physical interaction ComPPI
HSP90AA1 YTHDC2 25348397 N/A physical interaction ComPPI
NTRK1 YTHDC2 25348397 N/A physical interaction ComPPI
AXIN1 YTHDC2 22682247 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPU YTHDC2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NXF2 YTHDC2 25348397 N/A physical interaction ComPPI
DCTN1 YTHDC2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
IRAK1 YTHDC2 25348397 N/A physical interaction ComPPI
GABARAP YTHDC2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MYO6 YTHDC2 25348397 N/A physical interaction ComPPI
CAND1 YTHDC2 25348397 N/A physical interaction ComPPI
SRPK2 YTHDC2 25348397 N/A physical interaction ComPPI
FBXW11 YTHDC2 25348397 N/A physical interaction ComPPI
IFI16 YTHDC2 25348397 N/A physical interaction ComPPI
TARDBP YTHDC2 25348397 N/A physical interaction ComPPI
GSTO1 YTHDC2 25348397 N/A physical interaction ComPPI
RPS14 YTHDC2 25348397 N/A physical interaction ComPPI
GABARAPL1 YTHDC2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
LYAR YTHDC2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
FBL YTHDC2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
FGF8 YTHDC2 25348397 N/A physical interaction ComPPI
MNDA YTHDC2 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
SIRT7 YTHDC2 25348397 N/A physical interaction ComPPI
NOP53 YTHDC2 25348397 N/A physical interaction ComPPI
ZBTB38 YTHDC2 25348397 N/A physical interaction ComPPI
TP53 YTHDC2 22653443 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
HSP90AA2P YTHDC2 25348397 N/A physical interaction ComPPI
USP42 YTHDC2 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YTHDC2 CCDC8 25348397 N/A physical interaction ComPPI
YTHDC2 CC2D2A 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
YTHDC2 ZNF550 25348397 N/A physical interaction ComPPI
YTHDC2 ZNF512 25348397 N/A physical interaction ComPPI
YTHDC2 ZSCAN31 25348397 N/A physical interaction ComPPI
YTHDC2 ZNF324B 25348397 N/A physical interaction ComPPI
YTHDC2 WDR46 25348397 N/A physical interaction ComPPI
DICER1 YTHDC2 21858095 24234451 association anti tag coimmunoprecipitation IntAct
SMARCA2 YTHDC2 24234451 30021884 physical association cross-linking study IntAct
IRAK1 YTHDC2 21903422 27898060 N/A N/A OmniPath

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