GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
TRIM46 |
FullNmae |
tripartite motif containing 46 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:19019 |
EnsembleID |
ENSG00000163462 |
Uniprot |
Q7Z4K8 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
TRIM46 |
ferroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
TRIM46 |
GO:0001578,GO:0001764,GO:0005856,GO:0007409,GO:0008270,GO:0030517,GO:0032880,GO:0043194,GO:0044304,GO:0044304,GO:0048490,GO:0099612,GO:1901953,GO:1904115,GO:1990769 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
ETS1 |
TRIM46 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
SMARCA4 |
TRIM46 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
TRIM46 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
TRIM46 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
TRIM46 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
TRIM46 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXP1 |
TRIM46 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
TRIM46 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
VDR |
TRIM46 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
TK1 |
TRIM46 |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
RNF7 |
TRIM46 |
22493164
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
CBLC |
TRIM46 |
22493164
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
NTRK1 |
TRIM46 |
25348397
|
N/A |
physical interaction |
ComPPI |
MDM4 |
TRIM46 |
22493164
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
BRCA1 |
TRIM46 |
22493164
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
UCHL5 |
TRIM46 |
25348397
|
N/A |
physical interaction |
ComPPI |
USP1 |
TRIM46 |
25348397
|
N/A |
physical interaction |
ComPPI |
USP2 |
TRIM46 |
25348397
|
N/A |
physical interaction |
ComPPI |
TRIM46 |
USP15 |
25348397
|
N/A |
physical interaction |
ComPPI |
TRIM46 |
RNF125 |
22493164
24234451
25348397
|
physical association |
two hybrid,physical interaction,two hybrid array |
ComPPI,IntAct |
TRIM46 |
APP |
25348397
|
N/A |
physical interaction |
ComPPI |
TRIM46 |
MTNR1B |
24234451
25348397
26514267
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
Visualization