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GENE：KDM5A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KDM5A
FullNmae lysine demethylase 5A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9886
EnsembleID ENSG00000073614
Uniprot P29375

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KDM5A ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KDM5A GO:0000122,GO:0000785,GO:0000976,GO:0003677,GO:0003713,GO:0004857,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005730,GO:0006338,GO:0006355,GO:0008270,GO:0031490,GO:0032452,GO:0032922,GO:0034647,GO:0034647,GO:0035064,GO:0042393,GO:0045893,GO:0051090,GO:0140718

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 KDM5A 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 KDM5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA KDM5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 KDM5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 KDM5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 KDM5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 KDM5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A KDM5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 KDM5A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC KDM5A N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 KDM5A 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00002C0FCB KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000204177 KDM5A 23824327 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00001383CF KDM5A 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 KDM5A 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 KDM5A 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE KDM5A 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000215483 KDM5A 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000039607D KDM5A 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 KDM5A 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000939AF KDM5A 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000450F92 KDM5A 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005CE28 KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEF5F KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000038446A KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD02D KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016FF9C KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001D4A78 KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC379 KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 KDM5A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 KDM5A 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 KDM5A 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AKT1 KDM5A 22135298 phosphorylation N/A PhosphoSite
SUZ12 KDM5A 25361965 interaction type N/A PTMCode2
KDM5A SUZ12 25361965 interaction type N/A PTMCode2
LMO2 KDM5A 25361965 interaction type N/A PTMCode2
KDM5A LMO2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MORF4L2 KDM5A 25348397 N/A physical interaction ComPPI
RARA KDM5A 11358960 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
EZH2 KDM5A 25348397 N/A physical interaction ComPPI
TBP KDM5A 14525934 25348397 7935440 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RB1 KDM5A 14525934 22615382 24234451 25348397 7935440 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,biochemical,in vitro ComPPI,HPRD,IntAct
VDR KDM5A 11358960 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
KDM5A LMO2 14525934 25348397 27898060 9129143 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
KDM5A ESR1 11358960 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
KDM5A RBL1 14525934 25348397 7935440 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
KDM5A NR3C1 11358960 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
KDM5A H3C15 25348397 N/A physical interaction ComPPI
KDM5A MXD1 25348397 N/A physical interaction ComPPI
KDM5A EED 25348397 N/A physical interaction ComPPI
KDM5A SUZ12 25348397 N/A physical interaction ComPPI
KDM5A MORF4L1 25348397 N/A physical interaction ComPPI
KDM5A SIN3B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KDM5A HDAC2 25348397 N/A physical interaction ComPPI
KDM5A RBPJ 20231316 25348397 27898060 N/A physical interaction ComPPI,OmniPath
KDM5A HDAC1 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KDM5A H3-4 25348397 N/A physical interaction ComPPI
KDM5A GATAD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KDM5A RBBP7 25348397 N/A physical interaction ComPPI
KDM5A TM9SF4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KDM5A PHF12 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KDM5A FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
KDM5A EMSY 25348397 N/A physical interaction ComPPI
KDM5A ZNF131 25348397 N/A physical interaction ComPPI
KDM5A TRIM25 25348397 N/A physical interaction ComPPI
KDM5A CCT6A 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
KDM5A H3C1 18483221 27898060 inhibition N/A OmniPath

Visualization










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