Gene Information gene info

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GENE：CIRBP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CIRBP
FullNmae cold inducible RNA binding protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1982
EnsembleID ENSG00000099622
Uniprot Q14011

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CIRBP ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CIRBP GO:0003723,GO:0003723,GO:0003730,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005681,GO:0005737,GO:0005737,GO:0009409,GO:0009411,GO:0010494,GO:0017148,GO:0030371,GO:0034063,GO:0045727,GO:0048026,GO:0048255,GO:0070181

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CIRBP TLR4 23180781 24097189 physical association surface plasmon resonance array InnateDB
CIRBP LY96 23180781 24097189 physical association surface plasmon resonance array InnateDB
CIRBP AGER 23180781 24097189 physical association surface plasmon resonance array InnateDB
CIRBP TLR2 23180781 24097189 physical association surface plasmon resonance array InnateDB
RNF2 CIRBP 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
BMI1 CIRBP 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 CIRBP 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 CIRBP 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CIRBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CIRBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CIRBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CIRBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CIRBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CIRBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CIRBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR CIRBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 CIRBP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 CIRBP 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
SF3A2 CIRBP 25361965 interaction type N/A PTMCode2
CIRBP SF3A2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HNRNPK CIRBP 21516116 22365833 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ORC1 CIRBP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL5 CIRBP 25348397 N/A physical interaction ComPPI
SNRPA CIRBP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LXN CIRBP 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53BP1 CIRBP 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
ATXN1 CIRBP 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
BMI1 CIRBP 25348397 N/A physical interaction ComPPI
KHDRBS2 CIRBP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HNRNPH2 CIRBP 25348397 N/A physical interaction ComPPI
DUSP23 CIRBP 25348397 N/A physical interaction ComPPI
SF3A2 CIRBP 17332742 24234451 25348397 physical association affinity chromatography technology,physical interaction ComPPI,IntAct
KHDRBS1 CIRBP 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
JUN CIRBP 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 CIRBP 25348397 N/A physical interaction ComPPI
PAXIP1 CIRBP 25348397 N/A physical interaction ComPPI
SRF CIRBP 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CUL3 CIRBP 25348397 N/A physical interaction ComPPI
PRMT1 CIRBP 11850402 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PRNP CIRBP 18482256 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
PLK1 CIRBP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CSNK2A1 CIRBP 22113938 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
PRKAR2A CIRBP 25348397 N/A physical interaction ComPPI
PRMT5 CIRBP 25348397 N/A physical interaction ComPPI
TPR CIRBP 25348397 N/A physical interaction ComPPI
HABP4 CIRBP 21771594 24234451 25348397 physical association two hybrid ComPPI,IntAct
TMPO CIRBP 25348397 N/A physical interaction ComPPI
NEDD8 CIRBP 25348397 N/A physical interaction ComPPI
CUL2 CIRBP 25348397 N/A physical interaction ComPPI
WDR77 CIRBP 25348397 N/A physical interaction ComPPI
PAPOLA CIRBP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL1 CIRBP 25348397 N/A physical interaction ComPPI
EGFR CIRBP 25348397 N/A physical interaction ComPPI
RNF2 CIRBP 25348397 N/A physical interaction ComPPI
GTF2F1 CIRBP 25348397 N/A physical interaction ComPPI
CCNB2 CIRBP 25348397 N/A physical interaction ComPPI
RTN4 CIRBP 25348397 N/A physical interaction ComPPI
CDC14B CIRBP 25348397 N/A physical interaction ComPPI
SF1 CIRBP 25348397 N/A physical interaction ComPPI
VCAM1 CIRBP 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
NARS1 CIRBP 25348397 N/A physical interaction ComPPI
PRKN CIRBP 25348397 N/A physical interaction ComPPI
RBMX CIRBP 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
CAND1 CIRBP 25348397 N/A physical interaction ComPPI
FOXA1 CIRBP 25348397 N/A physical interaction ComPPI
RBMY1A1 CIRBP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SRSF3 CIRBP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BARD1 CIRBP 25348397 N/A physical interaction ComPPI
SMURF1 CIRBP 25348397 N/A physical interaction ComPPI
ELAVL1 CIRBP 25348397 N/A physical interaction ComPPI
NOP56 CIRBP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NUP88 CIRBP 25348397 N/A physical interaction ComPPI
ZFAND6 CIRBP 25348397 N/A physical interaction ComPPI
ESR1 CIRBP 25348397 N/A physical interaction ComPPI
KHSRP CIRBP 25348397 N/A physical interaction ComPPI
CIRBP PRNP 25348397 N/A physical interaction ComPPI
CIRBP APP 25348397 N/A physical interaction ComPPI
CIRBP CNOT3 25348397 N/A physical interaction ComPPI
CIRBP LSM14A 25348397 N/A physical interaction ComPPI
CIRBP CAPRIN1 25348397 N/A physical interaction ComPPI
CIRBP TMPO 25348397 N/A physical interaction ComPPI
CIRBP POLR1C 25348397 N/A physical interaction ComPPI
CIRBP FN1 25348397 N/A physical interaction ComPPI
CIRBP HNRNPA0 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CIRBP IL7R 25348397 N/A physical interaction ComPPI
CIRBP BAG5 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CIRBP LNX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CIRBP RBMY1F 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CIRBP MOV10 25348397 N/A physical interaction ComPPI
CIRBP NXF1 25348397 N/A physical interaction ComPPI
CIRBP NAA20 25348397 N/A physical interaction ComPPI
CIRBP AHSA1 25348397 N/A physical interaction ComPPI
CIRBP HNRNPA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CIRBP NANOGP8 25348397 N/A physical interaction ComPPI
CIRBP NANOG 25348397 N/A physical interaction ComPPI
CIRBP RC3H1 25348397 N/A physical interaction ComPPI
CIRBP COPRS 25348397 N/A physical interaction ComPPI
CIRBP RIOK1 25348397 N/A physical interaction ComPPI
CIRBP NGRN 25348397 N/A physical interaction ComPPI
CIRBP PAIP2B 25348397 N/A physical interaction ComPPI
CIRBP PRMT6 25348397 N/A physical interaction ComPPI
CIRBP GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
LYAR CIRBP 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MALSU1 CIRBP 25348397 N/A physical interaction ComPPI
YARS2 CIRBP 25348397 N/A physical interaction ComPPI
PSPH CIRBP 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MRPL1 CIRBP 25348397 N/A physical interaction ComPPI
NCBP3 CIRBP 24234451 26382858 association pull down IntAct
CIRBP TLR4 24097189 27898060 N/A N/A OmniPath
CIRBP TLR2 24097189 27898060 N/A N/A OmniPath
CIRBP LY96 24097189 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00008BFCD4 CIRBP 27087310 direct interaction,inhibition N/A NPInter
URS00009B0E56 CIRBP 27087310 direct interaction,inhibition N/A NPInter

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