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GENE：YAP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol YAP1
FullNmae Yes1 associated transcriptional regulator
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16262
EnsembleID ENSG00000137693
Uniprot P46937

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
YAP1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
YAP1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
YAP1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
YAP1 cuproptosis 38515849 In the present study, analysis of data downloaded from TCGA database revealed that YAP1 was positively associated with genes related to copper-induced cell death in patients with melanoma.This evidence showed that YAP1 can regulate cuproptosis in SKCM. regulator

Go Annotation:

GeneSymbol Go id
YAP1 GO:0000122,GO:0000902,GO:0000976,GO:0000978,GO:0001570,GO:0001674,GO:0001829,GO:0001894,GO:0002067,GO:0003015,GO:0003143,GO:0003682,GO:0003713,GO:0003713,GO:0003713,GO:0003714,GO:0003714,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0006974,GO:0008283,GO:0010628,GO:0010629,GO:0010837,GO:0016020,GO:0030054,GO:0030216,GO:0030307,GO:0030857,GO:0030859,GO:0030903,GO:0032570,GO:0033148,GO:0035019,GO:0035265,GO:0035329,GO:0035329,GO:0035329,GO:0042060,GO:0045599,GO:0045669,GO:0045747,GO:0045893,GO:0045893,GO:0045944,GO:0045944,GO:0048339,GO:0048368,GO:0050673,GO:0050679,GO:0050767,GO:0050847,GO:0060045,GO:0060070,GO:0060242,GO:0060449,GO:0060487,GO:0060576,GO:0061026,GO:0065003,GO:0065003,GO:0070064,GO:0070102,GO:0070161,GO:0071300,GO:0071480,GO:0072091,GO:0072307,GO:0090263,GO:0097191,GO:0140297,GO:0140552,GO:0140552,GO:1900182,GO:1902018,GO:1902459,GO:1903703,GO:1904036,GO:2000737,GO:2001237

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
YAP1 hsa:10413 path:hsa04390 Hippo signaling pathway - Homo sapiens (human)
YAP1 hsa:10413 path:hsa04392 Hippo signaling pathway - multiple species - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YAP1 WWTR1 12807903 18280240 18617895 21666501 23708000 25502501 26192618 26711338 7782338 association N/A ACSN
YAP1 SERPINE1 12807903 18280240 18617895 21666501 23708000 25502501 26192618 26711338 7782338 interaction type N/A ACSN
CDC42EP3 YAP1 26192618 26711338 27248291 interaction type N/A ACSN
ITCH YAP1 10940313 11318614 16469705 16861923 18552861 18628966 21107885 21383157 26192618 interaction type N/A ACSN
ABL1 YAP1 10837221 11804596 11971963 12628935 12709442 15459660 18835194 19788416 21051857 21199784 21435002 26192618 9168117 interaction type N/A ACSN
EGR1 YAP1 19137013 23180781 physical association anti tag coimmunoprecipitation,protein array InnateDB
BAX YAP1 19137013 23180781 physical association anti tag coimmunoprecipitation InnateDB
YAP1 SMAD7 12118366 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR YAP1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 YAP1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 YAP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 YAP1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A YAP1 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 YAP1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 YAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA YAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF YAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 YAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 YAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 YAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS YAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 YAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A YAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF YAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 YAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000008DA94 YAP1 23340296 rna interference,inhibition western blot miRSponge
URS0000324096 YAP1 17699775 25416803 mrna cleavage,inhibition array technology TarBase
URS00000ED600 YAP1 20215506 21856745 24892549 25416803 27832783 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000008DA94 YAP1 23340296 25416803 mrna cleavage,inhibition western blot TarBase
URS000003ABC4 YAP1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000003E1A9 YAP1 24242138 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS0000171CD1 YAP1 25416803 25743273 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000039A25B YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000070B1D YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000038718E YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002E628F YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000052EA98 YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002FB065 YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F YAP1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004AE8D3 YAP1 25416803 25846731 26550114 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000040780F YAP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000016D2D4 YAP1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F YAP1 25416803 27432214 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000040EE1D YAP1 25416803 28356122 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000F0F49 YAP1 25416803 27500472 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
AURKA YAP1 22135298 phosphorylation N/A PhosphoSite
LATS1 YAP1 22135298 phosphorylation N/A PhosphoSite
STK38 YAP1 22135298 phosphorylation N/A PhosphoSite
PRKAA1 YAP1 22135298 phosphorylation N/A PhosphoSite
STK38L YAP1 22135298 phosphorylation N/A PhosphoSite
CDK1 YAP1 22135298 phosphorylation N/A PhosphoSite
ABL1 YAP1 22135298 phosphorylation N/A PhosphoSite
NLK YAP1 22135298 phosphorylation N/A PhosphoSite
STK3 YAP1 22135298 phosphorylation N/A PhosphoSite
LATS2 YAP1 22135298 phosphorylation N/A PhosphoSite
PRKCZ YAP1 22135298 phosphorylation N/A PhosphoSite
AKT1 YAP1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
KPNA2 YAP1 25348397 N/A physical interaction ComPPI
PIN1 YAP1 25348397 N/A physical interaction ComPPI
SNRPB YAP1 25348397 N/A physical interaction ComPPI
YES1 YAP1 23245941 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
VPS4B YAP1 25348397 N/A physical interaction ComPPI
TSNAX YAP1 25348397 N/A physical interaction ComPPI
PALS1 YAP1 24234451 24255178 24366813 25348397 colocalization,association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RPL9 YAP1 25348397 N/A physical interaction ComPPI
NPM1 YAP1 25348397 N/A physical interaction ComPPI
PSMC6 YAP1 25348397 N/A physical interaction ComPPI
PPP2R1A YAP1 25348397 N/A physical interaction ComPPI
STAT1 YAP1 25348397 N/A physical interaction ComPPI
TUBB YAP1 25348397 N/A physical interaction ComPPI
TK1 YAP1 25348397 N/A physical interaction ComPPI
AMOT YAP1 19615732 24234451 24255178 24366813 24976009 25348397 25751139 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
WBP2 YAP1 14525934 24234451 24255178 24366813 25283809 25348397 25751139 7644498 association anti tag coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
VCP YAP1 25348397 N/A physical interaction ComPPI
NUBP2 YAP1 25348397 N/A physical interaction ComPPI
YWHAG YAP1 14525934 15324660 17353931 24234451 24255178 24366813 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,proximity-dependent biotin identification ComPPI,HPRD,IntAct
RAN YAP1 25348397 N/A physical interaction ComPPI
UBE2D1 YAP1 25348397 N/A physical interaction ComPPI
TP53BP2 YAP1 11278422 14525934 24234451 24255178 24366813 25348397 25751139 colocalization,association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid fragment pooling approach,in vitro,in vivo,tandem affinity purification,proximity-dependent biotin identification ComPPI,HPRD,IntAct
CTNND1 YAP1 21376238 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
DDX17 YAP1 24234451 24581491 25348397 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,molecular sieving,fluorescence microscopy ComPPI,IntAct
PRRG2 YAP1 17502622 24234451 25283809 25348397 physical association two hybrid,isothermal titration calorimetry,pull down,physical interaction ComPPI,IntAct
RPL10A YAP1 25348397 N/A physical interaction ComPPI
EGLN3 YAP1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
NF2 YAP1 24234451 24255178 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMAD1 YAP1 19914168 24234451 25348397 physical association anti tag coimmunoprecipitation,isothermal titration calorimetry,physical interaction ComPPI,IntAct
ZYX YAP1 25348397 N/A physical interaction ComPPI
ERBB4 YAP1 14525934 15023535 24234451 25283809 25348397 N/A two hybrid,experimental interaction detection,isothermal titration calorimetry,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
SMAD7 YAP1 12118366 14525934 22921829 24234451 25283809 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,isothermal titration calorimetry,nuclear magnetic resonance,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
MPDZ YAP1 24234451 24255178 24366813 25348397 colocalization,association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
FBXW7 YAP1 25348397 N/A physical interaction ComPPI
SND1 YAP1 25348397 N/A physical interaction ComPPI
JUN YAP1 25348397 N/A physical interaction ComPPI
RUNX2 YAP1 10228168 14525934 24234451 25348397 25751140 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
SMAD2 YAP1 25348397 N/A physical interaction ComPPI
SMARCD1 YAP1 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SUMO1 YAP1 25348397 N/A physical interaction ComPPI
EP300 YAP1 25348397 N/A physical interaction ComPPI
SMAD3 YAP1 25348397 N/A physical interaction ComPPI
HIF1A YAP1 24234451 25348397 25438054 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKD1 YAP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SMAD5 YAP1 25348397 N/A physical interaction ComPPI
SLC9A3R1 YAP1 10562288 14525934 24234451 25348397 colocalization,physical association affinity chromatography technology,anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,imaging technique,in vitro,in vivo ComPPI,HPRD,IntAct
UBE2L3 YAP1 25348397 N/A physical interaction ComPPI
ITGB1 YAP1 25348397 N/A physical interaction ComPPI
TGM2 YAP1 25348397 N/A physical interaction ComPPI
GSK3B YAP1 24234451 24976009 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SLC9A3R2 YAP1 16166090 24234451 24255178 25348397 27173435 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PDIA3 YAP1 25348397 N/A physical interaction ComPPI
YWHAB YAP1 17974916 19439659 20048001 24234451 24255178 24366813 25348397 association,physical association anti tag coimmunoprecipitation,coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAZ YAP1 15161933 24234451 24255178 25348397 25670079 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,confocal microscopy ComPPI,IntAct
PRKAA1 YAP1 24234451 25348397 25751139 25751140 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
PFKP YAP1 25348397 N/A physical interaction ComPPI
ARFIP1 YAP1 25348397 N/A physical interaction ComPPI
ACTN1 YAP1 25348397 N/A physical interaction ComPPI
ENO1 YAP1 25348397 N/A physical interaction ComPPI
CDH1 YAP1 21376238 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BTRC YAP1 21900206 24234451 24976009 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
AXIN1 YAP1 24234451 24976009 25348397 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct,OmniPath
THBS1 YAP1 25348397 N/A physical interaction ComPPI
YBX1 YAP1 25348397 N/A physical interaction ComPPI
COPA YAP1 25348397 N/A physical interaction ComPPI
PARP1 YAP1 25348397 N/A physical interaction ComPPI
XRCC5 YAP1 25348397 N/A physical interaction ComPPI
RRBP1 YAP1 25348397 N/A physical interaction ComPPI
ENAH YAP1 25348397 N/A physical interaction ComPPI
SMARCA4 YAP1 25348397 N/A physical interaction ComPPI
IGFBP7 YAP1 25348397 N/A physical interaction ComPPI
HSP90B1 YAP1 25348397 N/A physical interaction ComPPI
PRDX1 YAP1 25348397 N/A physical interaction ComPPI
XRN2 YAP1 25348397 N/A physical interaction ComPPI
PSMA5 YAP1 25348397 N/A physical interaction ComPPI
PPP1CA YAP1 24234451 24255178 24366813 25348397 25751139 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
MAP2K1 YAP1 24211253 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,fluorescence microscopy ComPPI,IntAct
HNRNPU YAP1 14525934 15096513 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
TRIP6 YAP1 25348397 N/A physical interaction ComPPI
XRCC6 YAP1 25348397 N/A physical interaction ComPPI
EEF1A1 YAP1 25348397 N/A physical interaction ComPPI
IQGAP1 YAP1 21376238 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CAD YAP1 25348397 N/A physical interaction ComPPI
PA2G4 YAP1 25348397 N/A physical interaction ComPPI
PDLIM7 YAP1 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARID1B YAP1 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
KLF5 YAP1 25348397 N/A physical interaction ComPPI
PARD3 YAP1 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TP73 YAP1 11278685 14525934 18280240 24234451 25283809 25348397 N/A experimental interaction detection,isothermal titration calorimetry,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
AHNAK YAP1 25348397 N/A physical interaction ComPPI
RAPGEF6 YAP1 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBM10 YAP1 25348397 N/A physical interaction ComPPI
EPRS1 YAP1 25348397 N/A physical interaction ComPPI
XPO1 YAP1 11027275 18573877 25348397 27898060 9857197 N/A physical interaction ComPPI,OmniPath
YWHAQ YAP1 12535517 14525934 22863277 24234451 24255178 24366813 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
TMPO YAP1 25348397 N/A physical interaction ComPPI
PSMC5 YAP1 25348397 N/A physical interaction ComPPI
RPS6 YAP1 25348397 N/A physical interaction ComPPI
UBQLN2 YAP1 25348397 N/A physical interaction ComPPI
UBA2 YAP1 25348397 N/A physical interaction ComPPI
HNRNPA2B1 YAP1 25348397 N/A physical interaction ComPPI
SRSF2 YAP1 25348397 N/A physical interaction ComPPI
NEDD8 YAP1 25348397 N/A physical interaction ComPPI
PAPOLA YAP1 25348397 N/A physical interaction ComPPI
H1-4 YAP1 25348397 N/A physical interaction ComPPI
SV2B YAP1 25348397 N/A physical interaction ComPPI
RPL7A YAP1 25348397 N/A physical interaction ComPPI
EGFR YAP1 25348397 N/A physical interaction ComPPI
SEPTIN2 YAP1 25348397 N/A physical interaction ComPPI
RAB11A YAP1 24234451 25348397 28468127 physical association anti bait coimmunoprecipitation ComPPI,IntAct
YWHAH YAP1 24234451 24255178 24366813 25348397 25751139 colocalization,association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
SFN YAP1 24234451 25348397 25670079 association physical interaction,chromatin immunoprecipitation assay ComPPI,IntAct
YWHAE YAP1 24234451 24255178 24366813 25348397 25751139 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
HDAC2 YAP1 25348397 N/A physical interaction ComPPI
H1-5 YAP1 25348397 N/A physical interaction ComPPI
LMNB1 YAP1 25348397 N/A physical interaction ComPPI
CDC20 YAP1 25348397 N/A physical interaction ComPPI
CCT5 YAP1 25348397 N/A physical interaction ComPPI
PHB2 YAP1 25348397 N/A physical interaction ComPPI
HSPA4 YAP1 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KLF4 YAP1 24234451 25348397 25531778 N/A anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT16H YAP1 25348397 N/A physical interaction ComPPI
YAP1 TEAD4 11358867 14525934 24234451 24525233 25348397 25751139 25751140 26592798 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,pull down,physical interaction,comigration in non denaturing gel electrophoresis,in vitro,in vivo,bio-layer interferometry ComPPI,HPRD,IntAct
YAP1 TEAD2 20368466 24234451 25348397 25751139 association isothermal titration calorimetry,nuclear magnetic resonance,pull down,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,IntAct
YAP1 TEAD3 11358867 14525934 24234451 24255178 24366813 25348397 25751139 colocalization,association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification,proximity-dependent biotin identification ComPPI,HPRD,IntAct
YAP1 WBP1 11604498 14525934 24234451 25283809 25348397 27898060 7644498 9202023 N/A experimental interaction detection,isothermal titration calorimetry,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
YAP1 SCAMP3 14525934 19158374 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
YAP1 RUNX1 10228168 14525934 24234451 25283809 25348397 N/A two hybrid,experimental interaction detection,isothermal titration calorimetry,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
YAP1 AKT1 12535517 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
YAP1 KIF5A 25348397 N/A physical interaction ComPPI
YAP1 RUNX3 25348397 N/A physical interaction ComPPI
YAP1 TP63 11278685 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
YAP1 SMAD6 25348397 N/A physical interaction ComPPI
YAP1 ITCH 25348397 N/A physical interaction ComPPI
YAP1 FBXW11 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
YAP1 ELAVL1 25348397 N/A physical interaction ComPPI
YAP1 LATS2 24234451 25348397 25751139 association physical interaction,tandem affinity purification ComPPI,IntAct
YAP1 LATS1 22863277 24234451 24255178 24366813 25283809 25348397 25751139 phosphorylation reaction,association anti tag coimmunoprecipitation,isothermal titration calorimetry,physical interaction,protein kinase assay,tandem affinity purification ComPPI,IntAct
YAP1 PML 25348397 N/A physical interaction ComPPI
YAP1 PTPN14 24234451 24255178 24366813 25283809 25348397 25751139 association anti tag coimmunoprecipitation,isothermal titration calorimetry,physical interaction,tandem affinity purification ComPPI,IntAct
YAP1 POLR2A 25348397 N/A physical interaction ComPPI
YAP1 AMOTL2 24234451 24255178 24366813 25348397 25751139 colocalization,association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
YAP1 AHCYL1 25348397 N/A physical interaction ComPPI
YAP1 SULT1A1 25348397 N/A physical interaction ComPPI
YAP1 UNK 25348397 N/A physical interaction ComPPI
YAP1 ZFYVE19 25348397 N/A physical interaction ComPPI
YAP1 IGBP1 25348397 N/A physical interaction ComPPI
YAP1 THUMPD1 25348397 N/A physical interaction ComPPI
YAP1 ZPR1 25348397 N/A physical interaction ComPPI
YAP1 USP9X 25348397 N/A physical interaction ComPPI
YAP1 TTC9C 25348397 N/A physical interaction ComPPI
YAP1 UCHL3 25348397 N/A physical interaction ComPPI
YAP1 UFM1 25348397 N/A physical interaction ComPPI
YAP1 UBE2C 25348397 N/A physical interaction ComPPI
YAP1 UBXN7 25348397 N/A physical interaction ComPPI
YAP1 TEAD1 22863277 24234451 24255178 24581491 24882516 25348397 25751139 25751140 26258633 colocalization,association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
YAP1 CREB1 25348397 N/A physical interaction ComPPI
YAP1 AMOTL1 24234451 24255178 24366813 25348397 25751139 colocalization,association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
YAP1 ARID1A 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
YAP1 ATP5IF1 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YAP1 BCL9L 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
YAP1 CCDC85C 24234451 24255178 25348397 25751139 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
YAP1 DPF2 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
YAP1 PATJ 24234451 24255178 24366813 25348397 colocalization,association anti tag coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
YAP1 LIN7C 24234451 24255178 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YAP1 RAE1 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YAP1 RAPGEF2 24234451 24255178 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YAP1 RASSF8 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
YAP1 TJP2 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YAP1 PRMT3 25348397 N/A physical interaction ComPPI
YAP1 RTF1 25348397 N/A physical interaction ComPPI
YAP1 TOM1 25348397 N/A physical interaction ComPPI
YAP1 ABL1 14525934 18280240 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
YAP1 MOV10 25348397 N/A physical interaction ComPPI
YAP1 NXF1 25348397 N/A physical interaction ComPPI
YAP1 FAM189B 25348397 N/A physical interaction ComPPI
YAP1 PRRG4 25348397 N/A physical interaction ComPPI
YAP1 CYYR1 25348397 N/A physical interaction ComPPI
YAP1 ARRDC1 25348397 N/A physical interaction ComPPI
YAP1 LDLRAD4 25348397 N/A physical interaction ComPPI
YAP1 STUB1 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YAP1 CPVL 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YAP1 ERP44 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YAP1 FASN 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YAP1 HSPH1 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YAP1 HSPA4L 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YAP1 HYOU1 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YAP1 MCMBP 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YAP1 PTCH1 24234451 25283809 25348397 N/A isothermal titration calorimetry,physical interaction ComPPI,IntAct
YAP1 PTPN21 25348397 N/A physical interaction ComPPI
YAP1 BAG4 25348397 N/A physical interaction ComPPI
YAP1 CTNNB1 21376238 22234184 23245941 24234451 24976009 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,inference by socio-affinity scoring ComPPI,IntAct
YAP1 NUDT5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
YAP1 EEF1A1P5 25348397 N/A physical interaction ComPPI
YAP1 WWC3 25348397 N/A physical interaction ComPPI
YAP1 HRNR 25348397 N/A physical interaction ComPPI
YAP1 RPL6 25348397 N/A physical interaction ComPPI
YAP1 EIF3B 25348397 N/A physical interaction ComPPI
YAP1 SUN2 25348397 N/A physical interaction ComPPI
YAP1 SLC25A5 25348397 N/A physical interaction ComPPI
YAP1 PSMD2 25348397 N/A physical interaction ComPPI
YAP1 DDX3X 25348397 N/A physical interaction ComPPI
YAP1 RPS4X 25348397 N/A physical interaction ComPPI
YAP1 FAM120A 25348397 N/A physical interaction ComPPI
YAP1 NCL 25348397 N/A physical interaction ComPPI
YAP1 CSTF1 25348397 N/A physical interaction ComPPI
YAP1 TMPO 25348397 N/A physical interaction ComPPI
YAP1 MAP4 25348397 N/A physical interaction ComPPI
YAP1 USP15 25348397 N/A physical interaction ComPPI
YAP1 RPL18 25348397 N/A physical interaction ComPPI
YAP1 SF3B3 25348397 N/A physical interaction ComPPI
YAP1 FLG2 25348397 N/A physical interaction ComPPI
YAP1 HSPB1 25348397 N/A physical interaction ComPPI
YAP1 CCT2 25348397 N/A physical interaction ComPPI
YAP1 PRPF8 25348397 N/A physical interaction ComPPI
YAP1 EIF4B 25348397 N/A physical interaction ComPPI
YAP1 CYFIP1 25348397 N/A physical interaction ComPPI
YAP1 MATR3 25348397 N/A physical interaction ComPPI
YAP1 TUBB6 25348397 N/A physical interaction ComPPI
YAP1 PSMC2 25348397 N/A physical interaction ComPPI
YAP1 EIF3L 25348397 N/A physical interaction ComPPI
YAP1 HNRNPR 25348397 N/A physical interaction ComPPI
YAP1 IMMT 25348397 N/A physical interaction ComPPI
YAP1 RPS8 25348397 N/A physical interaction ComPPI
YAP1 CAVIN1 25348397 N/A physical interaction ComPPI
YAP1 NUMA1 25348397 N/A physical interaction ComPPI
YAP1 SRSF6 25348397 N/A physical interaction ComPPI
YAP1 OGDH 25348397 N/A physical interaction ComPPI
YAP1 RPL24 25348397 N/A physical interaction ComPPI
YAP1 PHGDH 25348397 N/A physical interaction ComPPI
YAP1 IPO5 25348397 N/A physical interaction ComPPI
YAP1 TSR1 25348397 N/A physical interaction ComPPI
YAP1 ATAD3A 25348397 N/A physical interaction ComPPI
YAP1 RPL19 25348397 N/A physical interaction ComPPI
YAP1 PGAM5 25348397 N/A physical interaction ComPPI
YAP1 SEC16A 25348397 N/A physical interaction ComPPI
YAP1 AJUBA 25348397 N/A physical interaction ComPPI
YAP1 UPF1 25348397 N/A physical interaction ComPPI
YAP1 RPL15 25348397 N/A physical interaction ComPPI
YAP1 RPL13A 25348397 N/A physical interaction ComPPI
YAP1 CNN2 25348397 N/A physical interaction ComPPI
YAP1 HDAC1 25348397 N/A physical interaction ComPPI
YAP1 RBBP7 25348397 N/A physical interaction ComPPI
YAP1 PRDX6 25348397 N/A physical interaction ComPPI
YAP1 UQCRC2 25348397 N/A physical interaction ComPPI
YAP1 MVD 25348397 N/A physical interaction ComPPI
YAP1 MYH10 25348397 N/A physical interaction ComPPI
YAP1 PLOD2 25348397 N/A physical interaction ComPPI
YAP1 PSMD6 25348397 N/A physical interaction ComPPI
YAP1 ADSS2 25348397 N/A physical interaction ComPPI
YAP1 PAICS 25348397 N/A physical interaction ComPPI
YAP1 FUBP1 25348397 N/A physical interaction ComPPI
YAP1 CIAPIN1 25348397 N/A physical interaction ComPPI
YAP1 SFXN1 25348397 N/A physical interaction ComPPI
YAP1 DNAJC10 25348397 N/A physical interaction ComPPI
YAP1 PTBP1 25348397 N/A physical interaction ComPPI
YAP1 ANXA5 25348397 N/A physical interaction ComPPI
YAP1 WDR1 25348397 N/A physical interaction ComPPI
YAP1 SPINDOC 25348397 N/A physical interaction ComPPI
YAP1 MACROH2A1 25348397 N/A physical interaction ComPPI
YAP1 RTN4 25348397 N/A physical interaction ComPPI
YAP1 H1-10 25348397 N/A physical interaction ComPPI
YAP1 ACTL6A 25348397 N/A physical interaction ComPPI
YAP1 RPL17 25348397 N/A physical interaction ComPPI
YAP1 TWF1 25348397 N/A physical interaction ComPPI
YAP1 RPL21 25348397 N/A physical interaction ComPPI
YAP1 JPT2 25348397 N/A physical interaction ComPPI
YAP1 TAZ 25348397 N/A physical interaction ComPPI
YAP1 TBK1 25348397 N/A physical interaction ComPPI
YAP1 IKBKE 25348397 N/A physical interaction ComPPI
YAP1 RARG 25348397 N/A physical interaction ComPPI
YAP1 PRKAG1 24234451 25348397 25751139 association physical interaction,tandem affinity purification ComPPI,IntAct
YAP1 CTNNA1 21376238 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
YAP1 CTNNA2 21376238 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
YAP1 CDH3 21376238 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
YAP1 TBX5 23245941 24234451 25348397 association,physical association anti tag coimmunoprecipitation,chromatin immunoprecipitation assay ComPPI,IntAct
YAP1 VGLL4 24234451 24525233 25348397 association pull down ComPPI,IntAct
YAP1 WWTR1 24234451 24976009 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
YAP1 SOCS6 24234451 25180228 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct,OmniPath
YAP1 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
MED28 YAP1 16964398 24234451 25348397 physical association peptide array ComPPI,IntAct
NFE2 YAP1 14525934 25348397 9305852 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HNRNPF YAP1 25348397 N/A physical interaction ComPPI
PSMB4 YAP1 25348397 N/A physical interaction ComPPI
RPL14 YAP1 25348397 N/A physical interaction ComPPI
VPS25 YAP1 25348397 N/A physical interaction ComPPI
DEFA6 YAP1 25348397 N/A physical interaction ComPPI
YAP1 SCRIB 24234451 30126976 N/A p8 filamentous phage display IntAct
YAP1 SHANK1 24234451 30126976 N/A p8 filamentous phage display IntAct
EGR1 YAP1 19137013 27898060 N/A N/A OmniPath
YAP1 LY6E 19106090 27898060 N/A N/A OmniPath
YAP1 CTNNB1 22234184 23245941 23607968 27898060 stimulant N/A OmniPath
SLC9A3R1 YAP1 10562288 27898060 N/A N/A OmniPath
YAP1 ITCH 19788416 27898060 inhibition N/A OmniPath
MAPK9 YAP1 17081983 18669648 21364637 27898060 N/A N/A OmniPath
STK38 YAP1 18640976 24462114 24658687 25180175 25601544 25751140 27898060 N/A N/A OmniPath
CSNK1E YAP1 23431053 24715453 27898060 inhibition N/A OmniPath
YAP1 SMAD1 19914168 21685363 23431053 27898060 stimulant N/A OmniPath
AKT1 YAP1 12535517 20153295 20729916 20823509 21376238 21666719 21730131 24362629 24812269 25109332 25195862 25360797 25373897 25531778 25739674 25772246 25998128 26039999 26119935 26265440 26364602 27898060 inhibition N/A OmniPath
PML YAP1 19111660 19788416 27898060 stimulant N/A OmniPath
ABL1 YAP1 18280240 18701449 19788416 20841568 25361080 27898060 stimulant N/A OmniPath
CDK1 YAP1 12535517 24101154 25605730 25751139 27898060 N/A N/A OmniPath
LATS1 YAP1 15302935 17889669 17974916 18158288 18220336 18413746 18640976 18669648 20048001 20841485 21041411 21383157 22641346 22658639 22863277 24107629 24255178 24366813 25283809 27898060 inhibition,stimulant N/A OmniPath
SUMO1 YAP1 19788416 27898060 stimulant N/A OmniPath
CSNK1D YAP1 23431053 24715453 27898060 inhibition N/A OmniPath
LATS2 YAP1 15302935 17974916 18158288 18220336 18413746 18565851 18640976 18669648 19141641 19797269 19919647 20048001 21041410 21041411 21832154 21909427 22658639 22863277 23027127 23752589 25670202 26578655 26598551 27898060 inhibition N/A OmniPath
YAP1 DVL1 23178811 27898060 inhibition N/A OmniPath
YAP1 TP73 11278685 15678106 15893728 17110958 17889669 18280240 18640976 19111660 19788416 21808241 25283809 27898060 stimulant N/A OmniPath
MAPK8 YAP1 17081983 18669648 21364637 27898060 N/A N/A OmniPath
BTRC YAP1 20048001 21900206 23431053 27898060 inhibition N/A OmniPath
YAP1 RUNX2 10228168 14765127 22153608 27898060 inhibition N/A OmniPath
TJP2 YAP1 20868367 23829894 27898060 inhibition N/A OmniPath
YAP1 SMAD7 12118366 22921829 25283809 27898060 stimulant N/A OmniPath
CTNNA1 YAP1 23431053 27898060 inhibition N/A OmniPath
YAP1 TEAD4 11358867 23431053 24525233 25751139 25751140 26592798 27898060 stimulant N/A OmniPath
CTNNA2 YAP1 23431053 27898060 inhibition N/A OmniPath
AMOT YAP1 19615732 21205866 21808241 22385262 23564455 24101513 24106267 24225952 24255178 24366813 27898060 inhibition N/A OmniPath
YAP1 TEAD1 11358867 22863277 23431053 24255178 24581491 24882516 27898060 stimulant N/A OmniPath
YAP1 TEAD2 11358867 20368466 23431053 25751139 27898060 stimulant N/A OmniPath
YAP1 TEAD3 11358867 23431053 24255178 24366813 27898060 stimulant N/A OmniPath

Visualization










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