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GENE：PIEZO1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PIEZO1
FullNmae piezo type mechanosensitive ion channel component 1 (Er blood group)
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28993
EnsembleID ENSG00000103335
Uniprot Q92508

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PIEZO1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PIEZO1 GO:0005261,GO:0005261,GO:0005515,GO:0005783,GO:0005783,GO:0005789,GO:0005886,GO:0005886,GO:0006812,GO:0008381,GO:0010831,GO:0031258,GO:0033116,GO:0033625,GO:0033634,GO:0042391,GO:0050982,GO:0071260,GO:0098655

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 PIEZO1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C PIEZO1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PIEZO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PIEZO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PIEZO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PIEZO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 PIEZO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PIEZO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PIEZO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PIEZO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PIEZO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR PIEZO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PIEZO1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004AC389 PIEZO1 22322955 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00004AC389 PIEZO1 22322955 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000041FA2C PIEZO1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BD6DC PIEZO1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009EA8F PIEZO1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000ECE9C PIEZO1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004E02F2 PIEZO1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE PIEZO1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A PIEZO1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000116F83 PIEZO1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 PIEZO1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000246356 PIEZO1 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
YIPF3 PIEZO1 25348397 N/A physical interaction ComPPI
DSTN PIEZO1 25348397 N/A physical interaction ComPPI
VAPA PIEZO1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAB7A PIEZO1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM25 PIEZO1 25348397 N/A physical interaction ComPPI
RAB5C PIEZO1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SORD PIEZO1 25348397 N/A physical interaction ComPPI
GJB2 PIEZO1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GOLT1B PIEZO1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TSPAN5 PIEZO1 25348397 N/A physical interaction ComPPI

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