Gene Information gene info

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GENE：PTPN6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTPN6
FullNmae protein tyrosine phosphatase non-receptor type 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9658
EnsembleID ENSG00000111679
Uniprot P29350

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTPN6 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTPN6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTPN6 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PTPN6 GO:0000165,GO:0000278,GO:0001784,GO:0001784,GO:0001784,GO:0002244,GO:0002924,GO:0004725,GO:0004725,GO:0004726,GO:0005001,GO:0005515,GO:0005576,GO:0005634,GO:0005654,GO:0005654,GO:0005730,GO:0005737,GO:0005737,GO:0005829,GO:0005911,GO:0006470,GO:0007186,GO:0008284,GO:0008285,GO:0016020,GO:0017124,GO:0018108,GO:0019221,GO:0019901,GO:0030154,GO:0030154,GO:0030220,GO:0031295,GO:0032715,GO:0032720,GO:0032991,GO:0033007,GO:0033630,GO:0035335,GO:0035335,GO:0035556,GO:0035580,GO:0035855,GO:0042098,GO:0042105,GO:0042130,GO:0042169,GO:0042267,GO:0042981,GO:0043409,GO:0045577,GO:0050732,GO:0050839,GO:0050852,GO:0050853,GO:0050860,GO:0051279,GO:0051897,GO:0060338,GO:0070062,GO:0070372,GO:0070527,GO:0106015,GO:0140031,GO:1904724,GO:1905867,GO:2000045

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PTPN6 hsa:5777 path:hsa04148 Efferocytosis - Homo sapiens (human)
PTPN6 hsa:5777 path:hsa04520 Adherens junction - Homo sapiens (human)
PTPN6 hsa:5777 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)
PTPN6 hsa:5777 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
PTPN6 hsa:5777 path:hsa04660 T cell receptor signaling pathway - Homo sapiens (human)
PTPN6 hsa:5777 path:hsa04662 B cell receptor signaling pathway - Homo sapiens (human)
PTPN6 hsa:5777 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
PTPN6 hsa:5777 path:hsa05140 Leishmaniasis - Homo sapiens (human)
PTPN6 hsa:5777 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
PTPN6 hsa:5777 path:hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PTPN11 PTPN6 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 17371980 19833085 20007250 20038811 20363967 20435894 21469115 22437870 22483603 22513334 22683124 22952938 22955274 23732914 25355530 26192618 26667266 26755705 26885856 27474009 27806234 28893624 8976179 8986721 9751747 9765283 interaction type N/A ACSN
PTPN6 PDCD1 10358138 11447289 11572860 12138178 12176909 12707331 12773515 12917349 15240681 15699106 15713798 17371980 19833085 22437870 22513334 22952938 23732914 25355530 26192618 26667266 26885856 27474009 27806234 28893624 8976179 8986721 9751747 9765283 interaction type N/A ACSN
NECTIN2 PTPN6 12913096 19098271 22285893 26192618 26755705 interaction type N/A ACSN
PTPN6 CD226 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26192618 26667266 26755705 27474009 8976179 8986721 9751747 9765283 interaction type N/A ACSN
PTPN6 IL2 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26192618 26667266 26755705 27474009 8976179 8986721 9751747 9765283 interaction type N/A ACSN
PTPN6 IFNG 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26192618 26667266 26755705 27474009 8976179 8986721 9751747 9765283 interaction type N/A ACSN
PTPN6 IL10 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26192618 26667266 26755705 27474009 8976179 8986721 9751747 9765283 interaction type N/A ACSN
PTPN6 IL13 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26192618 26667266 26755705 27474009 8976179 8986721 9751747 9765283 interaction type N/A ACSN
PTPN6 STAT3 12176909 12773515 12917349 15240681 15713798 15870198 18508557 22513334 22952938 23180781 23331499 25355530 26192618 26667266 27474009 8976179 8986721 9765283 interaction type,inhibition,physical association anti tag coimmunoprecipitation ACSN,InnateDB,SignaLink,SignaLink
PTPN6 VAV1 12176909 12773515 12917349 15240681 15713798 22513334 22952938 25355530 26192618 26667266 27474009 8976179 8986721 9765283 interaction type N/A ACSN
HLA-C PTPN6 11513144 21339333 26192618 9605119 interaction type N/A ACSN
KIR2DL1 PTPN6 11513144 12515815 12917349 16606694 18574028 18835194 23180781 26192618 9751747 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
HLA-B PTPN6 11513144 11994457 26192618 8976179 8986721 9605119 9751747 interaction type N/A ACSN
KIR3DL1 PTPN6 11513144 11994457 26192618 8976179 8986721 9605119 9751747 interaction type N/A ACSN
HLA-E PTPN6 10358164 11015446 11062502 12731048 15120186 15536084 22464172 26192618 2731048 8478617 9485206 9486650 9655483 interaction type N/A ACSN
KLRD1 PTPN6 10358164 11015446 11062502 12731048 15120186 15536084 22464172 26192618 2731048 8478617 9485206 9486650 9655483 interaction type N/A ACSN
KIR2DL3 PTPN6 11513144 26192618 8574854 9751747 interaction type N/A ACSN
KIR2DL2 PTPN6 11513144 21339333 26192618 9605119 interaction type N/A ACSN
PTPN6 MAP3K7 17079228 23180781 dephosphorylation reaction,physical association anti tag coimmunoprecipitation,dephosphorylation reaction InnateDB
TLR10 PTPN6 16482509 23180781 physical association two hybrid InnateDB
IL2RB PTPN6 23180781 9520455 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 TYK2 14624462 18508557 23180781 23331499 29145629 8524272 8943354 dephosphorylation reaction,inhibition,physical association anti tag coimmunoprecipitation,inferred by curator InnateDB,Reactome,SignaLink,SignaLink
PTPN6 JAK1 23180781 23331499 8524272 9852037 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink,SignaLink
IFNAR1 PTPN6 18508557 23180781 29145629 8524272 8943354 dephosphorylation reaction,physical association anti tag coimmunoprecipitation,gst pull down,inferred by curator InnateDB,Reactome
PTPN6 JAK2 10772872 15983048 18988627 21071413 23180781 23331499 8943354 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink,SignaLink
PTPN6 IRF1 11483597 23180781 dephosphorylation reaction in gel phosphatase assay InnateDB
PTPN6 IRF8 11483597 16914719 23180781 dephosphorylation reaction,physical association anti tag coimmunoprecipitation,in gel phosphatase assay InnateDB
PTPN6 SRC 23180781 9261115 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 DNMT1 15870198 23180781 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 HDAC1 15870198 23180781 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 CEACAM1 18836450 23180781 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 TLR2 18836450 23180781 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 IL4R 23180781 9065461 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 CD33 10206955 10887109 17947393 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
PTPN6 SIGLEC9 10887109 15292262 23180781 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 SIGLEC5 19596804 23180781 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 BCL6 19965633 23180781 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 CD46 11858824 23180781 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 SMAD3 18729074 23180781 physical association tandem affinity purification InnateDB
PTPN6 LAIR1 11171044 11328818 23180781 physical association two hybrid InnateDB
PTPN6 GRB2 11171044 11328818 23180781 physical association two hybrid InnateDB
HBA1 PTPN6 11171044 23180781 physical association two hybrid InnateDB
PTPN6 PILRA 11171044 11328818 23180781 physical association two hybrid InnateDB
PTPN6 SIGLEC10 11328818 11733002 12163025 23180781 physical association anti tag coimmunoprecipitation,two hybrid,pull down InnateDB
PTPN6 LILRB4 12163025 23180781 physical association two hybrid InnateDB
PTPN6 LILRB2 12163025 23180781 physical association two hybrid InnateDB
PTPN6 SIGLEC7 10499918 15292262 23180781 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 SYK 12763134 23180781 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 ZAP70 10458769 12763134 23109003 23180781 8638162 inhibition,physical association anti tag coimmunoprecipitation InnateDB,SignaLink
PTPN6 CD22 11551923 23180781 8627166 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 CD19 23180781 9120258 physical association anti tag coimmunoprecipitation InnateDB
CD22 PTPN6 11551923 23180781 23836650 29145629 7618087 9890995 physical association anti tag coimmunoprecipitation,inferred by curator InnateDB,Reactome
PTPN6 EGR1 20690147 23180781 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 NFAT5 20351292 23180781 physical association anti tag coimmunoprecipitation InnateDB
PTPN6 KIR3DL1 15187115 23180781 physical association anti tag coimmunoprecipitation InnateDB
LST1 PTPN6 22589543 23180781 physical association anti tag coimmunoprecipitation InnateDB
GH1 PTPN6 24243840 29145629 physical association inferred by curator Reactome
GHR PTPN6 24243840 29145629 physical association inferred by curator Reactome
GH2 PTPN6 24243840 29145629 physical association inferred by curator Reactome
PTPN6 PTPN6 24243840 29145629 physical association inferred by curator Reactome
IGHD PTPN6 23836650 29145629 7618087 9890995 physical association inferred by curator Reactome
IGHM PTPN6 23836650 29145629 7618087 9890995 physical association inferred by curator Reactome
IGKC PTPN6 23836650 29145629 7618087 9890995 physical association inferred by curator Reactome
CD79A PTPN6 23836650 29145629 7618087 9890995 physical association inferred by curator Reactome
PTPN6 CD79B 23836650 29145629 7618087 9890995 physical association inferred by curator Reactome
HLA-DQA1 PTPN6 12947224 15358536 18173375 18759926 29145629 dephosphorylation reaction inferred by curator Reactome
HLA-DPA1 PTPN6 12947224 15358536 18173375 18759926 29145629 dephosphorylation reaction inferred by curator Reactome
HLA-DQA2 PTPN6 12947224 15358536 18173375 18759926 29145629 dephosphorylation reaction inferred by curator Reactome
HLA-DRA PTPN6 12947224 15358536 18173375 18759926 29145629 dephosphorylation reaction inferred by curator Reactome
JAK1 PTPN6 18508557 24243840 29145629 8943354 dephosphorylation reaction inferred by curator Reactome
PTPN6 STAT2 18508557 29145629 8943354 dephosphorylation reaction inferred by curator Reactome
PTPN6 IFNGR2 24243840 29145629 dephosphorylation reaction inferred by curator Reactome
IFNGR1 PTPN6 24243840 29145629 dephosphorylation reaction inferred by curator Reactome
IFNG PTPN6 24243840 29145629 dephosphorylation reaction inferred by curator Reactome
PTPN6 JAK3 11021818 18988627 23331499 9520455 stimulation N/A SignaLink,SignaLink
PTPN6 SOCS1 14551136 23331499 stimulation N/A SignaLink,SignaLink
PTPN6 STAT6 12459556 12791978 23331499 stimulation N/A SignaLink
PTPN6 ROS1 11266449 23331499 stimulation N/A SignaLink
PTPN6 LCK 10488096 10574931 11294838 12468540 15489916 23109003 23331499 7512963 8114715 8692915 inhibition,stimulation N/A SignaLink,SignaLink
PDCD1 PTPN6 11160222 15240681 15358536 23109003 chemical activation reaction N/A SignaLink
CTLA4 PTPN6 23109003 9256472 chemical activation reaction N/A SignaLink
PTPN6 PIK3R1 10488096 11526404 15032589 21780115 22880054 23109003 inhibition N/A SignaLink
MAPK1 PTPN6 12459785 16231973 23109003 inhibition N/A SignaLink
MAPK3 PTPN6 12459785 16231973 23109003 inhibition N/A SignaLink
LCK PTPN6 12459785 16231973 23109003 chemical activation reaction N/A SignaLink
PTPN6 CD247 11238643 23109003 inhibition N/A SignaLink

Source Target Pmid Interactiontype Methods Database
BLNK PTPN6 20005715 interaction type N/A PSP
CAV1 PTPN6 20005715 interaction type N/A PSP
DOK1 PTPN6 20005715 interaction type N/A PSP
GRB2 PTPN6 20005715 interaction type N/A PSP
IRS2 PTPN6 20005715 interaction type N/A PSP
IRS4 PTPN6 20005715 interaction type N/A PSP
LCP2 PTPN6 20005715 interaction type N/A PSP
PAG1 PTPN6 20005715 interaction type N/A PSP
PIK3R1 PTPN6 20005715 interaction type N/A PSP
SHC1 PTPN6 20005715 interaction type N/A PSP
TFG PTPN6 20005715 interaction type N/A PSP
CAV1 PTPN6 12176037 18988627 20005715 21071413 N/A N/A SignaLink
GRB2 PTPN6 20005715 N/A N/A SignaLink
DOK1 PTPN6 10585470 18988627 20005715 20005715 N/A N/A SignaLink
IRS4 PTPN6 12774026 18988627 20005715 20005715 N/A N/A SignaLink
PAG1 PTPN6 10790433 10790433 18988627 20005715 20005715 21071413 N/A N/A SignaLink
IRS2 PTPN6 12198247 18988627 20005715 20005715 N/A N/A SignaLink
LCP2 PTPN6 15588985 18988627 20005715 20005715 21071413 8760799 8760799 8760799 9765283 9765283 N/A N/A SignaLink
PIK3R1 PTPN6 11160222 20005715 20005715 21071413 N/A N/A SignaLink
SHC1 PTPN6 20005715 20005715 N/A N/A SignaLink
BLNK PTPN6 10903736 11356834 11356834 15588985 18988627 20005715 20005715 21071413 N/A N/A SignaLink
TFG PTPN6 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 PTPN6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PTPN6 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PTPN6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PTPN6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PTPN6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PTPN6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PTPN6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PTPN6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR PTPN6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 PTPN6 18948549 trascriptional regulation,stimulation inferred by curator TFlink
NPM1 PTPN6 16825495 trascriptional regulation,stimulation inferred by curator TFlink
PKNOX1 PTPN6 20864515 trascriptional regulation,stimulation inferred by curator TFlink
RELA PTPN6 18948549 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 PTPN6 14630083 15870198 16825495 21792937 trascriptional regulation,stimulation inferred by curator TFlink
USF1 PTPN6 12071971 trascriptional regulation,stimulation inferred by curator TFlink
USF2 PTPN6 12071971 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PTPN6 N/A trascriptional regulation,stimulation inferred by curator TFlink
MYC PTPN6 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001C0099 PTPN6 25416803 26081980 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000021D7C8 PTPN6 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000044FD7 PTPN6 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005FDE70 PTPN6 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004E02F2 PTPN6 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000ECE9C PTPN6 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003BD367 PTPN6 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002E728C PTPN6 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SRC PTPN6 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LCK PTPN6 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
INSR PTPN6 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
PRKCA PTPN6 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
LYN PTPN6 22135298 phosphorylation N/A PhosphoSite
SSTR2 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 SSTR2 25361965 interaction type N/A PTMCode2
LAIR1 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 LAIR1 25361965 interaction type N/A PTMCode2
BTLA PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 BTLA 25361965 interaction type N/A PTMCode2
SIRPA PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 SIRPA 25361965 interaction type N/A PTMCode2
CXCR4 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CXCR4 25361965 interaction type N/A PTMCode2
PDCD1 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 PDCD1 25361965 interaction type N/A PTMCode2
TYK2 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 TYK2 25361965 interaction type N/A PTMCode2
PTPN6 LCK 25361965 interaction type N/A PTMCode2
CSF2RB PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CSF2RB 25361965 interaction type N/A PTMCode2
PTPRC PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 PTPRC 25361965 interaction type N/A PTMCode2
PRKCD PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 PRKCD 25361965 interaction type N/A PTMCode2
PTK2B PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 PTK2B 25361965 interaction type N/A PTMCode2
LIFR PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 LIFR 25361965 interaction type N/A PTMCode2
IL4R PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 IL4R 25361965 interaction type N/A PTMCode2
GHR PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 GHR 25361965 interaction type N/A PTMCode2
KDR PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 KDR 25361965 interaction type N/A PTMCode2
PILRA PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 PILRA 25361965 interaction type N/A PTMCode2
IL6ST PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 IL6ST 25361965 interaction type N/A PTMCode2
CBL PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CBL 25361965 interaction type N/A PTMCode2
CD72 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CD72 25361965 interaction type N/A PTMCode2
IFNAR1 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 IFNAR1 25361965 interaction type N/A PTMCode2
TFG PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 TFG 25361965 interaction type N/A PTMCode2
ZAP70 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 ZAP70 25361965 interaction type N/A PTMCode2
CD247 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CD247 25361965 interaction type N/A PTMCode2
JAK1 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 JAK1 25361965 interaction type N/A PTMCode2
CD33 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CD33 25361965 interaction type N/A PTMCode2
LCP2 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 LCP2 25361965 interaction type N/A PTMCode2
EPOR PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 EPOR 25361965 interaction type N/A PTMCode2
STAT6 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 STAT6 25361965 interaction type N/A PTMCode2
CD5 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CD5 25361965 interaction type N/A PTMCode2
PTPN6 JAK3 25361965 interaction type N/A PTMCode2
JAK3 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 SHC1 25361965 interaction type N/A PTMCode2
SHC1 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 MPIG6B 25361965 interaction type N/A PTMCode2
MPIG6B PTPN6 25361965 interaction type N/A PTMCode2
CTNND1 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CTNND1 25361965 interaction type N/A PTMCode2
PTPN6 SRC 25361965 interaction type N/A PTMCode2
HBA1 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 HBA1 25361965 interaction type N/A PTMCode2
LILRA3 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 LILRA3 25361965 interaction type N/A PTMCode2
KLRC1 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 KLRC1 25361965 interaction type N/A PTMCode2
CD300LF PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CD300LF 25361965 interaction type N/A PTMCode2
EGFR PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 EGFR 25361965 interaction type N/A PTMCode2
ABL1 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 ABL1 25361965 interaction type N/A PTMCode2
SYK PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 SYK 25361965 interaction type N/A PTMCode2
KIT PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 KIT 25361965 interaction type N/A PTMCode2
GRB2 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 GRB2 25361965 interaction type N/A PTMCode2
SIGLEC10 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 SIGLEC10 25361965 interaction type N/A PTMCode2
CLEC4A PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CLEC4A 25361965 interaction type N/A PTMCode2
PTPN6 PRKCA 25361965 interaction type N/A PTMCode2
CD22 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CD22 25361965 interaction type N/A PTMCode2
PIK3R1 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 PIK3R1 25361965 interaction type N/A PTMCode2
CUZD1 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CUZD1 25361965 interaction type N/A PTMCode2
JAK2 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 JAK2 25361965 interaction type N/A PTMCode2
LILRB4 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 LILRB4 25361965 interaction type N/A PTMCode2
GAB2 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 GAB2 25361965 interaction type N/A PTMCode2
SOCS3 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 SOCS3 25361965 interaction type N/A PTMCode2
DOK1 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 DOK1 25361965 interaction type N/A PTMCode2
PTPN6 INSR 25361965 interaction type N/A PTMCode2
STAT5A PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 STAT5A 25361965 interaction type N/A PTMCode2
IL2RB PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 IL2RB 25361965 interaction type N/A PTMCode2
FCRL3 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 FCRL3 25361965 interaction type N/A PTMCode2
FLT3 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 FLT3 25361965 interaction type N/A PTMCode2
CD79A PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CD79A 25361965 interaction type N/A PTMCode2
CTNNB1 PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CTNNB1 25361965 interaction type N/A PTMCode2
BCR PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 BCR 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LCP2 PTPN6 14525934 15588985 25348397 8760799 9765283 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SPATA2 PTPN6 11160222 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
FHL3 PTPN6 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ROR2 PTPN6 25348397 N/A physical interaction ComPPI
LAT PTPN6 25348397 N/A physical interaction ComPPI
ANXA1 PTPN6 23754495 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RPL37A PTPN6 25348397 N/A physical interaction ComPPI
TRAF6 PTPN6 14500659 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PSMD7 PTPN6 25348397 N/A pull down ComPPI
RPL36AL PTPN6 25348397 N/A physical interaction ComPPI
TYK2 PTPN6 14525934 25348397 7629131 8780698 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN6 KIT 12614164 14525934 24234451 25348397 7684496 9528781 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN6 ROS1 11266449 14525934 17416557 24234451 25348397 dephosphorylation reaction,association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,phosphatase assay,in vivo,two hybrid ComPPI,HPRD,IntAct
PTPN6 LYN 10488096 10574931 11042209 12468540 14525934 22624718 24234451 25348397 8114715 8692915 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN6 CD72 14525934 15588985 25348397 9590210 9740800 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN6 CBL 12176909 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN6 IFNAR1 14525934 25348397 8524272 9029147 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PTPN6 PECAM1 24234451 25348397 9774457 association pull down,surface plasmon resonance,physical interaction,in vitro,in vivo ComPPI,IntAct
PTPN6 ZAP70 10458769 14525934 25348397 8638162 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PTPN6 PRKCD 11723252 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN6 SSTR2 11920268 14525934 25348397 27898060 9305905 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
PTPN6 SRC 12468645 14525934 25348397 8647855 9261115 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN6 TNFRSF1A 11786908 14525934 24234451 25348397 association experimental interaction detection,pull down,in vivo ComPPI,HPRD,IntAct
PTPN6 SYK 10072516 11356834 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PTPN6 IL6ST 10800945 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PTPN6 GHR 14525934 25348397 9632636 N/A experimental interaction detection,in vivo ComPPI,HPRD
PTPN6 CTNND1 10835420 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN6 CAV1 12176037 14525934 24234451 25348397 colocalization,physical association coimmunoprecipitation,cosedimentation through density gradient,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
PTPN6 SIRPA 10660565 10660620 14525934 14662855 24234451 25348397 8943344 9632768 physical association two hybrid,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
PTPN6 KHDRBS1 14525934 24234451 25348397 9045636 physical association coimmunoprecipitation,experimental interaction detection,in vitro ComPPI,HPRD,IntAct
PTPN6 DOK1 10585470 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PTPN6 IRS4 12774026 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPN6 STAT5B 14525934 25348397 9211920 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PTPN6 BLNK 10903736 11356834 14525934 15588985 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN6 PILRA 10660620 10903717 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,surface plasmon resonance,physical interaction,in vivo ComPPI,HPRD,IntAct
PTPN6 PAG1 10790433 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PTPN6 GAB2 11812650 11895767 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PTPN6 SLAMF6 11489943 14525934 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN6 SIGLEC11 11986327 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PTPN6 BTLA 12796776 14525934 14652006 24234451 25348397 association coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
PTPN6 CUZD1 12361947 14525934 15588985 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PTPN6 FCGR2B 14525934 24234451 25348397 7716523 8577729 9148918 9603468 association,physical association affinity chromatography technology,experimental interaction detection,proteinchip(r,pull down,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN6 PILRB 25348397 N/A two hybrid,in vitro ComPPI
PTPN6 TREML1 12393607 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
PTPN6 LILRB2 18802077 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction,in vitro ComPPI,IntAct
PTPN6 LILRB4 18802077 24234451 25348397 physical association anti bait coimmunoprecipitation,in vitro ComPPI,IntAct
PTPN6 SIGLEC12 11328818 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
PTPN6 CD300LF 14525934 14662855 15184070 15549731 24234451 25348397 27898060 association two hybrid,coimmunoprecipitation,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,IntAct,OmniPath
PTPN6 KLRB1 10229828 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
PTPN6 PIK3R1 10488096 11160222 11337495 14525934 24234451 25348397 association two hybrid,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
PTPN6 PTK2B 10521452 10747947 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN6 GRB2 10660620 11964172 14525934 24234451 25348397 25535246 8632004 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,far western blotting,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN6 CEACAM1 14525934 25348397 9867848 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPN6 CTNNB1 12571228 14525934 15588985 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
PTPN6 ACTN4 14525934 15070900 15588985 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPN6 MS4A2 14525934 25348397 9379041 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPN6 KIR2DL5A 14525934 15187115 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPN6 MYH9 12705885 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
PTPN6 FLT3 14525934 15831474 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPN6 PRKCA 14525934 15269224 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPN6 TFG 14525934 15557341 24234451 25348397 27898060 physical association experimental interaction detection,pull down,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
PTPN6 ACTN1 14525934 15070900 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPN6 KDR 14525934 16453023 18377662 24234451 25348397 9405464 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN6 IRS2 12198247 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
PTPN6 CD79A 14525934 25348397 7539038 N/A experimental interaction detection,in vivo ComPPI,HPRD
PTPN6 FAS 11786908 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PTPN6 IL2RB 14525934 25348397 9520455 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPN6 CD79B 14525934 25348397 7539038 N/A experimental interaction detection,in vivo ComPPI,HPRD
PTPN6 JAK1 14525934 25348397 7629131 9520455 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PTPN6 PTPN11 14525934 25348397 8541543 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PTPN6 CD247 14525934 14672952 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PTPN6 JAK3 14525934 25348397 9520455 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPN6 SHC1 14525934 25348397 8541543 N/A experimental interaction detection,in vivo ComPPI,HPRD
PTPN6 STAT6 12791978 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PTPN6 TLR10 14525934 16482509 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
PTPN6 TMEM62 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PTPN6 SIGLEC10 12163025 14525934 24234451 25348397 association two hybrid,experimental interaction detection,biochemical,in vivo,two hybrid ComPPI,HPRD,IntAct
PTPN6 KIR2DL3 14525934 24234451 25348397 8574854 8648092 8691154 9148918 association,physical association affinity chromatography technology,coimmunoprecipitation,experimental interaction detection,pull down,surface plasmon resonance,in vitro ComPPI,HPRD,IntAct
PTPN6 LAIR1 10660620 10764762 24234451 25348397 association,physical association two hybrid,coimmunoprecipitation,pull down,physical interaction,in vitro ComPPI,IntAct
PTPN6 VAV1 14525934 25348397 8632004 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN6 SOS1 14525934 25348397 8632004 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PTPN6 EGFR 14525934 24234451 25348397 9733788 association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN6 EPOR 14525934 24234451 25348397 7228577 7528537 7528577 7889566 association,physical association affinity chromatography technology,anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN6 ESR1 14525934 24234451 25348397 7539106 dephosphorylation reaction experimental interaction detection,phosphatase assay,in vitro ComPPI,HPRD,IntAct
PTPN6 CSF2RB 14525934 24234451 25348397 7528537 8246974 9162089 9254654 association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN6 HOXA10 12145285 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN6 INSR 12468540 14525934 25348397 7512963 8114715 8692915 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN6 IL4R 11714803 14525934 24234451 25348397 9392697 association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN6 JAK2 14525934 25348397 8943354 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PTPN6 BCR 14525934 25348397 9211920 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PTPN6 LIFR 10800945 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PTPN6 PTPRC 25348397 N/A in vivo ComPPI
PTPN6 CD5 10082557 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PTPN6 LCK 10488096 10574931 11294838 12468540 14525934 19167335 24234451 25348397 7512963 8114715 8692915 dephosphorylation reaction,phosphorylation reaction experimental interaction detection,physical interaction,protein kinase assay,phosphatase assay,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN6 CD33 10206955 10556798 14525934 17947393 24234451 25348397 association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,enzymatic study,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN6 KLRC1 14525934 25348397 9485206 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PTPN6 CXCR4 10506573 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PTPN6 NOS1 11511520 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN6 CD22 14525934 15588985 24234451 25348397 7618087 8627166 9890995 association,physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN6 ABL1 10488096 10574931 12468540 14525934 25348397 7512963 8114715 8692915 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PTPN6 MPIG6B 11544253 14525934 24234451 25348397 association coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
PTPN6 FCRL3 25348397 N/A physical interaction ComPPI
PTPN6 LILRB1 18802077 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PTPN6 TXN 25348397 N/A physical interaction ComPPI
PTPN6 SMAD3 25348397 N/A physical interaction,tandem affinity purification ComPPI
PTPN6 SAMD4B 25348397 N/A physical interaction ComPPI
PTPN6 PANK4 25348397 N/A physical interaction ComPPI
PTPN6 NSUN7 25348397 N/A physical interaction ComPPI
PTPN6 AIMP1 25348397 N/A physical interaction ComPPI
PTPN6 DARS1 25348397 N/A physical interaction ComPPI
PTPN6 PTPN2 25348397 N/A physical interaction ComPPI
PTPN6 PFKP 25348397 N/A physical interaction ComPPI
PTPN6 TRIP6 25348397 N/A physical interaction ComPPI
PTPN6 VARS1 25348397 N/A physical interaction ComPPI
PTPN6 OLIG1 25348397 N/A two hybrid,physical interaction ComPPI
PTPN6 PTK2 25348397 N/A two hybrid,physical interaction ComPPI
PTPN6 PLCG1 25348397 N/A physical interaction ComPPI
PTPN6 PLCG2 25348397 N/A physical interaction ComPPI
PTPN6 ERBB4 25348397 N/A physical interaction ComPPI
PTPN6 ERBB2 25348397 N/A physical interaction ComPPI
PTPN6 FGFR2 25348397 N/A physical interaction ComPPI
PTPN6 FGFR4 25348397 N/A physical interaction ComPPI
PTPN6 IGF1R 25348397 N/A physical interaction ComPPI
PTPN6 DUSP18 25348397 N/A physical interaction ComPPI
PTPN6 PTPN12 25348397 N/A physical interaction ComPPI
PTPN6 NUDT16 25348397 N/A physical interaction ComPPI
PTPN6 NMNAT1 25348397 N/A physical interaction ComPPI
PTPN6 MACROD1 25348397 N/A physical interaction ComPPI
PTPN6 RPL7L1 25348397 N/A physical interaction ComPPI
PTPN6 RPS19BP1 25348397 N/A physical interaction ComPPI
PTPN6 BRIX1 25348397 N/A physical interaction ComPPI
PTPN6 SRP14 25348397 N/A physical interaction ComPPI
PTPN6 GADD45GIP1 25348397 N/A physical interaction ComPPI
PTPN6 RPL30 25348397 N/A physical interaction ComPPI
PTPN6 EBNA1BP2 25348397 N/A physical interaction ComPPI
PTPN6 DIMT1 25348397 N/A physical interaction ComPPI
PTPN6 RPF2 25348397 N/A physical interaction ComPPI
PTPN6 RRS1 25348397 N/A physical interaction ComPPI
PTPN6 C8ORF33 25348397 N/A physical interaction ComPPI
PTPN6 RPL35A 25348397 N/A physical interaction ComPPI
PTPN6 SRSF5 25348397 N/A physical interaction ComPPI
PTPN6 CLTCL1 25348397 N/A physical interaction ComPPI
PTPN6 PA2G4 25348397 N/A physical interaction ComPPI
PTPN6 RPL18A 25348397 N/A physical interaction ComPPI
PTPN6 RPL22L1 25348397 N/A physical interaction ComPPI
PTPN6 RPP30 25348397 N/A physical interaction ComPPI
PTPN6 LMTK2 25348397 N/A physical interaction ComPPI
PTPN6 AATK 25348397 N/A physical interaction ComPPI
PTPN6 ERBB3 25348397 N/A physical interaction ComPPI
PTPN6 ROR1 25348397 N/A physical interaction ComPPI
PTPN6 PTK7 25348397 N/A physical interaction ComPPI
PTPN6 SIGLEC7 25348397 N/A physical interaction ComPPI
PTPN6 SIGLEC9 25348397 N/A physical interaction ComPPI
PTPN6 CDK1 25348397 N/A physical interaction ComPPI
PTPN6 FGFRL1 25348397 N/A physical interaction ComPPI
PTPN6 NFAT5 25348397 N/A anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,dephosphorylation reaction,physical interaction,protein phosphatase assay ComPPI
PTPN6 CAMK1 24234451 25348397 25915125 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PTPN6 MAP3K4 15601262 24234451 25348397 dephosphorylation reaction,colocalization experimental interaction detection,imaging technique ComPPI,IntAct
PTPN6 NTRK1 25348397 N/A anti bait coimmunoprecipitation ComPPI
PTPN6 CDH2 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
PTPN6 PDGFRB 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
PTPN6 PDCD1 15240681 24234451 25348397 association coimmunoprecipitation ComPPI,IntAct
PTPN6 SH3BP2 16649996 24234451 25348397 association pull down,surface plasmon resonance ComPPI,IntAct
PTPN6 KIR2DL1 24234451 25348397 8691146 association coimmunoprecipitation,pull down ComPPI,IntAct
PTPN6 CASP8 18086677 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
PTPN6 CD37 22624718 24234451 25348397 association,physical association anti bait coimmunoprecipitation ComPPI,IntAct
PTPN6 THEMIS 24234451 25348397 25535246 association,physical association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
PTPN6 CD244 11489943 24234451 24642916 25348397 association,physical association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
PTPN6 PSMD13 25348397 N/A pull down ComPPI
PTPN6 PSMD2 25348397 N/A pull down ComPPI
PTPN6 PSMD4 25348397 N/A pull down ComPPI
PTPN6 PSMD1 25348397 N/A pull down ComPPI
PTPN6 PSMC5 25348397 N/A pull down ComPPI
PTPN6 PSMD3 25348397 N/A pull down ComPPI
PTPN6 PSMD11 25348397 N/A pull down ComPPI
PTPN6 DUSP22 24234451 25348397 28330616 association pull down ComPPI,IntAct
PTPN6 CD300A 11489943 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PTPN6 LILRB3 18802077 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PTPN6 PTPN6 11920268 14525934 7518460 8574854 9151699 9531263 9842885 9973385 N/A experimental interaction detection HPRD
CLEC4A PTPN6 11178971 14525934 N/A experimental interaction detection HPRD
SRC PTPN6 10488096 12468540 12468645 14699166 14757045 16649996 17974954 27898060 8647855 9261115 stimulant N/A OmniPath
PTPN6 SRC 12468645 14699166 17974954 27898060 8647855 9261115 inhibition,stimulant N/A OmniPath
LCK PTPN6 10488096 10574931 10617656 11294838 12468540 16497976 19167335 27898060 7512963 8114715 8692915 stimulant N/A OmniPath
PTPN6 LCK 10488096 10574931 10617656 11294838 12468540 16497976 19167335 27898060 7512963 8114715 8692915 inhibition,stimulant N/A OmniPath
PRKCA PTPN6 15269224 27898060 inhibition,stimulant N/A OmniPath
LYN PTPN6 10488096 10574931 11042209 12468540 18083107 19690332 22624718 27898060 8114715 8692915 stimulant N/A OmniPath
PTPN6 LYN 10488096 10574931 11042209 12468540 15537644 22624718 27898060 8114715 8692915 inhibition N/A OmniPath
PTPN1 PTPN6 21123182 27898060 N/A N/A OmniPath
PTPN6 NTRK1 14662744 27898060 N/A N/A OmniPath
EGFR PTPN6 27898060 7518460 7673163 9733788 N/A N/A OmniPath
PTPN6 EGFR 27898060 7518460 7673163 9038217 9733788 inhibition,stimulant N/A OmniPath
PTPN6 ACTN1 15070900 27898060 inhibition N/A OmniPath
PTPN6 MAP3K7 17079228 27898060 N/A N/A OmniPath
PTPN6 IRF1 11483597 27898060 N/A N/A OmniPath
PTPN6 STAT6 12459556 12791978 1279198 27898060 inhibition,stimulant N/A OmniPath
PTPN6 JAK3 11021818 27898060 9520455 inhibition,stimulant N/A OmniPath
PTPN6 KDR 16453023 18377662 18840653 27898060 9405464 inhibition N/A OmniPath
PTPN6 SOCS1 14551136 27898060 stimulant N/A OmniPath
PTPN6 KIT 12614164 23416972 27898060 7684496 9528781 inhibition N/A OmniPath
PTPN6 ESR1 27898060 7539106 N/A N/A OmniPath
PTPN6 CTNND1 10835420 27898060 stimulant N/A OmniPath
PTPN6 NFAT5 20351292 27898060 inhibition N/A OmniPath
TLR10 PTPN6 16482509 27898060 N/A N/A OmniPath
TLR2 PTPN6 18836450 27898060 N/A N/A OmniPath
PTPN6 ACTG1 12646642 27898060 inhibition N/A OmniPath
GRB2 PTPN6 10660620 10747947 11171044 11328818 11964172 25535246 27898060 8632004 N/A N/A OmniPath
IFNAR1 PTPN6 27898060 8524272 9029147 N/A N/A OmniPath
MAPK3 PTPN6 12468540 14757045 27898060 7512963 N/A N/A OmniPath
PTPN6 JAK1 14624462 27898060 7629131 8524272 9520455 9852037 inhibition,stimulant N/A OmniPath
PTPN6 IRF8 11483597 16914719 27898060 N/A N/A OmniPath
IRF8 PTPN6 11483597 16914719 27898060 N/A N/A OmniPath
PTPN6 TYK2 14624462 27898060 7629131 8524272 8780698 inhibition N/A OmniPath
ABL1 PTPN6 10488096 10574931 12468540 16497976 20841568 27898060 7512963 8114715 8692915 stimulant N/A OmniPath
PTPN6 CASP8 18086677 27898060 inhibition,stimulant N/A OmniPath
CD19 PTPN6 27898060 9120258 N/A N/A OmniPath
PTPN6 HOXA10 12145285 27898060 N/A N/A OmniPath
INSR PTPN6 10734133 12468540 14551136 14699166 16497976 17675340 18377662 21900501 25535246 25876760 27898060 7512963 8114715 8692915 stimulant N/A OmniPath
PTPN6 INSR 10734133 12468540 27898060 7512963 8114715 8692915 inhibition N/A OmniPath
PTPN6 STAT3 18508557 27898060 inhibition,stimulant N/A OmniPath
IL4R PTPN6 11714803 27898060 9065461 9392697 N/A N/A OmniPath
PTPN6 IL4R 11714803 27898060 9065461 9392697 inhibition N/A OmniPath
JAK2 PTPN6 10772872 15983048 27898060 8943354 stimulant N/A OmniPath
PTPN6 JAK2 10772872 15983048 27898060 8943354 inhibition,stimulant N/A OmniPath
PTPN6 NOS1 11511520 27898060 N/A N/A OmniPath
SMAD3 PTPN6 18729074 27898060 N/A N/A OmniPath
PTPN6 ZAP70 10458769 12763134 27898060 8638162 inhibition,stimulant N/A OmniPath
ZAP70 PTPN6 10458769 12763134 27898060 8638162 N/A N/A OmniPath
PTPN6 CD72 11114375 12882840 15588985 27898060 9590210 9740800 inhibition N/A OmniPath
PTPN6 LAIR1 10660620 10764762 10903717 11160222 11171044 11328818 27898060 9285412 N/A N/A OmniPath
LAIR1 PTPN6 10660620 10764762 10903717 11160222 11171044 11328818 27898060 9285412 N/A N/A OmniPath
CEACAM1 PTPN6 18836450 27898060 9867848 N/A N/A OmniPath
PTPN6 KCNH2 12361947 27898060 inhibition N/A OmniPath
PTPN6 LILRB1 12163025 15474475 27898060 N/A N/A OmniPath
LILRB1 PTPN6 12163025 15474475 27898060 N/A N/A OmniPath
PTPN6 CSF2RB 11812650 27898060 7528537 8246974 9162089 9254654 inhibition N/A OmniPath
SIGLEC9 PTPN6 10887109 15292262 27898060 N/A N/A OmniPath
CD22 PTPN6 10228003 11356834 11551923 15588985 27898060 7618087 8627166 9890995 stimulant N/A OmniPath
PTPN6 CD22 10228003 11356834 11551923 15588985 27898060 7618087 8627166 9890995 N/A N/A OmniPath
PTPN6 ROS1 11266449 17416557 27898060 inhibition,stimulant N/A OmniPath
IL2RB PTPN6 27898060 9520455 N/A N/A OmniPath
PTPN6 IL2RB 27898060 9520455 inhibition N/A OmniPath
SIGLEC5 PTPN6 19596804 27898060 N/A N/A OmniPath
PTPN6 SYK 10072516 10458769 10747947 11356834 12763134 27898060 inhibition N/A OmniPath
CD46 PTPN6 11858824 27898060 N/A N/A OmniPath
SIGLEC10 PTPN6 11328818 11733002 12163025 27898060 N/A N/A OmniPath
PTPN6 HBA1 11171044 27898060 N/A N/A OmniPath
LILRB4 PTPN6 12163025 27898060 9151699 9973385 N/A N/A OmniPath
LILRB2 PTPN6 12163025 27898060 9531263 9842885 N/A N/A OmniPath
CD33 PTPN6 10206955 10556798 10887109 17947393 27898060 N/A N/A OmniPath
PTPN6 CD33 10206955 10556798 10887109 17947393 27898060 N/A N/A OmniPath
KIR2DL1 PTPN6 18574028 27898060 8691146 stimulant N/A OmniPath
SIGLEC7 PTPN6 10499918 15292262 27898060 N/A N/A OmniPath
PTPN6 PTK2B 10521452 10747947 27898060 inhibition N/A OmniPath
PTPN6 GAB2 11812650 11895767 27898060 N/A N/A OmniPath
PTPN6 PILRA 10660620 10903717 11171044 11328818 27898060 N/A N/A OmniPath
PILRA PTPN6 10660620 10903717 11171044 11328818 27898060 N/A N/A OmniPath
PTPN6 SH3BP2 16649996 27898060 inhibition N/A OmniPath
PTPN6 PECAM1 10350061 27898060 9774457 N/A N/A OmniPath

Visualization










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