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GENE：KDM5C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KDM5C
FullNmae lysine demethylase 5C
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11114
EnsembleID ENSG00000126012
Uniprot P41229

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KDM5C ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KDM5C GO:0000785,GO:0003677,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006338,GO:0006355,GO:0008270,GO:0009636,GO:0032452,GO:0032453,GO:0032453,GO:0034647,GO:0045892,GO:0048511

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 KDM5C 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A KDM5C 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
YBX1 KDM5C 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 KDM5C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KDM5C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 KDM5C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 KDM5C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 KDM5C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ARX KDM5C 23246292 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000075ABF4 KDM5C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE KDM5C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000048BA36 KDM5C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D KDM5C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000451A1 KDM5C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD KDM5C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000015A0D9 KDM5C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 KDM5C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F KDM5C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005DEC41 KDM5C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BF7F9 KDM5C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000519450 KDM5C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 KDM5C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000028BB8 KDM5C 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PCNA KDM5C 25348397 N/A physical interaction ComPPI
LSM2 KDM5C 25348397 N/A physical interaction ComPPI
SET KDM5C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
E2F6 KDM5C 17468742 24234451 25348397 26496610 association anti tag coimmunoprecipitation,cosedimentation through density gradient,physical interaction,tandem affinity purification ComPPI,IntAct
CALM1 KDM5C 25348397 N/A physical interaction ComPPI
RING1 KDM5C 17468742 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
EHMT2 KDM5C 17468742 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CENPK KDM5C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMAD3 KDM5C 25348397 N/A physical interaction ComPPI
NCOR1 KDM5C 17468742 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ACTN1 KDM5C 25348397 N/A physical interaction ComPPI
CSNK2A1 KDM5C 25348397 N/A physical interaction ComPPI
XPO1 KDM5C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPTBN2 KDM5C 25348397 N/A physical interaction ComPPI
HDAC2 KDM5C 17468742 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
H3C15 KDM5C 17320160 17320161 17468742 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SKP2 KDM5C 25348397 N/A physical interaction ComPPI
RNF2 KDM5C 17468742 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TFDP1 KDM5C 17468742 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
TSPYL2 KDM5C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MBD2 KDM5C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SSH3 KDM5C 25348397 N/A physical interaction ComPPI
CSNK2B KDM5C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAX KDM5C 17468742 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
REST KDM5C 17468742 24234451 25348397 association,physical association anti bait coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
L3MBTL1 KDM5C 17468742 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
USP5 KDM5C 25348397 N/A physical interaction ComPPI
TKT KDM5C 25348397 N/A physical interaction ComPPI
CBX3 KDM5C 17468742 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NXF1 KDM5C 25348397 N/A physical interaction ComPPI
HDAC1 KDM5C 17468742 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SLC25A22 KDM5C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MGA KDM5C 17468742 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
KDM5C IER2 25348397 N/A physical interaction ComPPI
KDM5C ZNF687 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KDM5C H3C1 17909537 27898060 inhibition N/A OmniPath

Visualization










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