Gene Information gene info

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GENE：CCDC6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CCDC6
FullNmae coiled-coil domain containing 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18782
EnsembleID ENSG00000108091
Uniprot Q16204

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CCDC6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CCDC6 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CCDC6 GO:0005200,GO:0005515,GO:0005829,GO:0005856,GO:0007010,GO:0008150,GO:0017124,GO:0042802

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CCDC6 hsa:8030 path:hsa05200 Pathways in cancer - Homo sapiens (human)
CCDC6 hsa:8030 path:hsa05216 Thyroid cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CCDC6 POLR2F 23180781 23994473 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR CCDC6 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 CCDC6 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 CCDC6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 CCDC6 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CCDC6 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 CCDC6 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 CCDC6 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 CCDC6 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 CCDC6 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CCDC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CCDC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CCDC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CCDC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CCDC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CCDC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CCDC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 CCDC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 CCDC6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC CCDC6 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001597DC CCDC6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000148B91 CCDC6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000157026 CCDC6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002C02E4 CCDC6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002B7450 CCDC6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA CCDC6 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS00001EFBE3 CCDC6 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS000050CCE0 CCDC6 22815788 25416803 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS00003E5ECC CCDC6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000BD6DC CCDC6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009EA8F CCDC6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F CCDC6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005F9738 CCDC6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 CCDC6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004AE8D3 CCDC6 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000020CEC2 CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000017DBB8 CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000412AC7 CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000759EB8 CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000019D79B CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000364FEF CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001799A3 CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C CCDC6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 CCDC6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB CCDC6 25416803 26835423 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CHEK1 CCDC6 22135298 phosphorylation N/A PhosphoSite
CDK2 CCDC6 22135298 phosphorylation N/A PhosphoSite
ATM CCDC6 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
PIN1 CCDC6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PDE4DIP CCDC6 25348397 N/A physical interaction ComPPI
ZNF774 CCDC6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RALBP1 CCDC6 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SORBS3 CCDC6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP2R1A CCDC6 24234451 25348397 26496610 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SKP1 CCDC6 23108047 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EGLN3 CCDC6 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
CD2AP CCDC6 25348397 N/A physical interaction ComPPI
PPP4C CCDC6 14525934 17353931 18715871 19156129 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
FBXW7 CCDC6 23108047 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP7 CCDC6 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAFF CCDC6 25348397 N/A physical interaction ComPPI
GSK3B CCDC6 25348397 N/A physical interaction ComPPI
YWHAB CCDC6 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 CCDC6 25348397 N/A physical interaction ComPPI
APC CCDC6 25348397 N/A physical interaction ComPPI
P4HB CCDC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP1CA CCDC6 25348397 N/A physical interaction ComPPI
CSNK2A1 CCDC6 22113938 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
PPP2CB CCDC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP2CA CCDC6 24234451 25348397 26496610 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PKM CCDC6 25348397 N/A protein kinase assay ComPPI
EXOC1 CCDC6 25348397 N/A physical interaction ComPPI
XPO1 CCDC6 25348397 N/A physical interaction ComPPI
MAPK7 CCDC6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CEP55 CCDC6 25348397 N/A physical interaction ComPPI
CUL1 CCDC6 23108047 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SEPTIN2 CCDC6 25348397 N/A physical interaction ComPPI
SF3A1 CCDC6 25348397 N/A physical interaction ComPPI
TRIM28 CCDC6 25348397 N/A physical interaction ComPPI
CCNB1 CCDC6 25348397 N/A physical interaction ComPPI
TRPC4AP CCDC6 25348397 N/A physical interaction ComPPI
LPXN CCDC6 25348397 N/A physical interaction ComPPI
NR3C1 CCDC6 25348397 N/A physical interaction ComPPI
PAX6 CCDC6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TFIP11 CCDC6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HNRNPR CCDC6 25348397 N/A physical interaction ComPPI
TRIM25 CCDC6 25348397 N/A physical interaction ComPPI
ELAVL1 CCDC6 25348397 N/A physical interaction ComPPI
ESR1 CCDC6 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
ESR2 CCDC6 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
LRSAM1 CCDC6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NUDC CCDC6 25348397 N/A physical interaction ComPPI
PPP4R1 CCDC6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP4R2 CCDC6 25348397 N/A physical interaction ComPPI
PCBP3 CCDC6 25348397 N/A physical interaction ComPPI
ATF5 CCDC6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LNX1 CCDC6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATF2 CCDC6 25348397 N/A physical interaction ComPPI
RPTOR CCDC6 25348397 N/A physical interaction ComPPI
MTMR7 CCDC6 25348397 N/A physical interaction ComPPI
TCP10L CCDC6 25348397 N/A physical interaction ComPPI
BRCC3 CCDC6 25348397 N/A physical interaction ComPPI
CREB1 CCDC6 25348397 N/A physical interaction ComPPI
MTUS2 CCDC6 25348397 N/A physical interaction ComPPI
C1S CCDC6 25348397 N/A physical interaction ComPPI
GAPVD1 CCDC6 25348397 N/A physical interaction ComPPI
CEP170 CCDC6 25348397 N/A physical interaction ComPPI
TCL1B CCDC6 25348397 N/A physical interaction ComPPI
PPP4R3B CCDC6 25348397 N/A physical interaction ComPPI
PAAF1 CCDC6 25348397 N/A physical interaction ComPPI
RASSF7 CCDC6 25348397 N/A physical interaction ComPPI
HDAC1 CCDC6 25348397 N/A physical interaction ComPPI
PPP4R3A CCDC6 25348397 N/A physical interaction ComPPI
GAS8 CCDC6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCDC6 ZNF444 25348397 N/A physical interaction ComPPI
CCDC6 DDI2 25348397 N/A physical interaction ComPPI
CCDC6 SARS1 25348397 N/A physical interaction ComPPI
CCDC6 POLG2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCDC6 CDK1 25348397 N/A physical interaction ComPPI
CCDC6 LZTS3 25348397 N/A physical interaction ComPPI
CCDC6 ZNF331 25348397 N/A physical interaction ComPPI
CCDC6 FBXO42 25348397 N/A physical interaction ComPPI
CCDC6 CCDC102A 25348397 N/A physical interaction ComPPI
CCDC6 ZNF445 25348397 N/A physical interaction ComPPI
CCDC6 NECAB1 25348397 N/A physical interaction ComPPI
CCDC6 TRIM14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCDC6 CYTH4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCDC6 LUZP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCDC6 REXO1L1P 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCDC6 ZNF835 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCDC6 CENPQ 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK3 CCDC6 14525934 14712216 15144186 15302935 N/A experimental interaction detection HPRD
CCDC6 CCDC6 24234451 physical association two hybrid array,two hybrid prey pooling approach IntAct
CDK2 CCDC6 14712216 15570572 27898060 stimulant N/A OmniPath
FBXW7 CCDC6 23108047 25885523 27898060 inhibition N/A OmniPath
ATM CCDC6 17420723 23108047 27898060 stimulant N/A OmniPath
MAPK3 CCDC6 14712216 15144186 15302935 16964243 17287340 18212344 18669648 18691976 19413330 19415658 19651622 19664994 19664995 20068231 20166139 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B29C8 CCDC6 27087310 direct interaction,inhibition N/A NPInter

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