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GENE：NFE2L2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NFE2L2
FullNmae NFE2 like bZIP transcription factor 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7782
EnsembleID ENSG00000116044
Uniprot Q16236

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NFE2L2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NFE2L2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NFE2L2 ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
NFE2L2 cuproptosis 36213577 We created a prognostic profile consisting of nineteen cuproptosis-related genes (NFE2L2, LIPT1, LIPT2, DLD, etc.) and their connected targets. retulator signature
NFE2L2 cuproptosis 38200445 In this study, four cuproptosis genes (i.e., NFE2L2, PDHA1, PDHB, and DLD) were found to have different roles in cuproptosis. regulator
NFE2L2 cuproptosis 38495196 Cuproptosis-related genes were manually curated, and differentially expressed cuproptosis-related genes (DECuGs) were identified.Then, the 16 DECuGs were obtained by the intersection of the 5018 DEGs and 63 cuproptosis-related genes. 63 cuproptosis-related genes
NFE2L2 cuproptosis 37983626 NFE2L2, NLRP3, GLS, LIPT1, and MTF1 were identified as potential cuproptosis predictors, thus shedding new light on ischemic stroke pathogenesis and heterogeneity. predictior
NFE2L2 cuproptosis 37983626 NFE2L2 (Nrf2) is an important transcription factor that regulates multiple biological pathways, including metal ion balance, heme/iron metabolism, and antioxidant activity. Nrf2 physiologically regulates oxidative stress and inflammation, has critical involvement in neuroprotection, and might be associated with cuproptosis. It stabilizes GPX4 activity and mitochondrial redox balance by controlling copper oxidation-related genes and glutathione regulatory genes. regulator
NFE2L2 cuproptosis 38348451 Namely Nrf2, a transcription factor that regulates antioxidant response element (ARE)-mediated genes. NFE2L2 activation can influence cellular redox status. CRGs in the cuproptosis pathway
NFE2L2 cuproptosis 38200445 These results pointed out that NFE2L2 is the most closely related cuproptosis gene that can predict the occurrence and development of PE, followed by PDHA1, PDHB, and DLD. GLS resulted as the least closely related to PE. related cuproptosis gene
NFE2L2 cuproptosis 36050740 A list of the cuproptosis-related genes was obtained from cuproptosis-related studies [18,19,20,21,22]. cuproptosis-related genes
NFE2L2 cuproptosis 36195876 We found that all the 18 cuproptosis-related genes have significant value for predicting the prognosis of LIHC patients. Among them, 13 genes are risk factors, including NFE2L2, NLRP3, ATP7A, LIPT1, LIPT2, DLD, DLAT, PDHA1, PDHB, MTF1, GLS, CDKN2A and DLST. And the others are favorable factors, including FDX1, ATP7B, SLC31A1, LIAS and DBT. cuproptosis-related genes
NFE2L2 cuproptosis 35964468 Cuproptosis-related gene sets were obtained from a previous study [9] and combined with the Molecular Signature Database (MsigDB) v7.0 database (http://www.gsea-msigdb.org/gsea/msigdb/, GOBP_CELLULAR_COPPER_ION_HOMEOSTASIS, GOBP_CELLULAR_RESPONSE_TO_COPPER_ION). Cuproptosis-related gene sets obtained from Molecular Signature Database (MsigDB) v7.18 database.
NFE2L2 cuproptosis 36313717 The details of ninety-six candidate cuproptosis-related genes involved in the copper homeostasis regulatory pathway, copper metabolism diseases, mitochondrial respiratory, and iron-sulfur cluster proteins were exhibited in聽Table S1. Cuproptosis genes related mitochondrial respiration
NFE2L2 cuproptosis 36818726 NLRP3, NFE2L2, ATP7A, LIPT1, GLS and MTF1 may serve as predictors of cuproptosis and play an important role in the pathogenesis of immune infiltration in IS. predictors of cuproptosis
NFE2L2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NFE2L2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NFE2L2 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
NFE2L2 GO:0000785,GO:0000976,GO:0000976,GO:0000978,GO:0000981,GO:0000981,GO:0001221,GO:0001228,GO:0002931,GO:0003677,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005794,GO:0005813,GO:0005829,GO:0005829,GO:0005886,GO:0006357,GO:0006357,GO:0006954,GO:0006979,GO:0010499,GO:0010628,GO:0010667,GO:0010976,GO:0016567,GO:0019904,GO:0030194,GO:0030968,GO:0031625,GO:0032993,GO:0034599,GO:0034599,GO:0034599,GO:0034599,GO:0036003,GO:0036499,GO:0036499,GO:0042149,GO:0043161,GO:0043536,GO:0043565,GO:0045088,GO:0045454,GO:0045766,GO:0045944,GO:0045944,GO:0045995,GO:0046223,GO:0046326,GO:0061419,GO:0061629,GO:0070301,GO:0070301,GO:0071280,GO:0071356,GO:0071466,GO:0071498,GO:0071499,GO:0090575,GO:0140467,GO:1900038,GO:1900407,GO:1902037,GO:1902176,GO:1903071,GO:1903788,GO:1904385,GO:1904753,GO:2000121,GO:2000352,GO:2000379

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NFE2L2 hsa:4780 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)
NFE2L2 hsa:4780 path:hsa05012 Parkinson disease - Homo sapiens (human)
NFE2L2 hsa:4780 path:hsa05200 Pathways in cancer - Homo sapiens (human)
NFE2L2 hsa:4780 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
NFE2L2 hsa:4780 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
NFE2L2 hsa:4780 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)
NFE2L2 hsa:4780 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NFE2L2 KEAP1 19560419 23850759 26192618 interaction type N/A ACSN
NFE2L2 SRXN1 10441483 10821856 10874044 11279008 11909699 12356737 12511571 15521073 16219762 17512463 18761713 19027064 19747488 23850759 26192618 interaction type N/A ACSN
CUL3 NFE2L2 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759 26192618 interaction type N/A ACSN
RBX1 NFE2L2 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759 26192618 interaction type N/A ACSN
NFE2L2 HMOX1 10441483 10821856 10874044 11279008 11909699 12356737 12511571 15521073 16219762 17512463 18761713 19027064 19747488 23850759 26192618 interaction type N/A ACSN
NFE2L2 PRDX1 10441483 10821856 10874044 11279008 11909699 12356737 12511571 15521073 16219762 17512463 18761713 19027064 19747488 23850759 26192618 interaction type N/A ACSN
NFE2L2 TXNRD1 10441483 10821856 10874044 11279008 11909699 12356737 12511571 15521073 16219762 17512463 18761713 19027064 19747488 23850759 26192618 interaction type N/A ACSN
NFE2L2 TXN 10441483 10821856 10874044 11279008 11909699 12356737 12511571 15521073 16219762 17512463 18761713 19027064 19747488 23850759 26192618 interaction type N/A ACSN
NFE2L2 GCLC 10441483 10821856 10874044 11279008 11909699 12356737 12511571 15521073 16219762 17512463 18761713 19027064 19666106 19747488 23180781 23850759 26192618 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
NFE2L2 JUN 19666106 23180781 physical association anti tag coimmunoprecipitation InnateDB
NFE2L2 GCLM 19666106 23180781 physical association anti tag coimmunoprecipitation InnateDB
CFTR NFE2L2 20309604 23180781 physical association anti tag coimmunoprecipitation InnateDB
NQO1 NFE2L2 20309604 23180781 physical association anti tag coimmunoprecipitation InnateDB
YY1 NFE2L2 20309604 23180781 physical association anti tag coimmunoprecipitation InnateDB
SQSTM1 NFE2L2 20452972 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR NFE2L2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 NFE2L2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 NFE2L2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 NFE2L2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 NFE2L2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 NFE2L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NFE2L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NFE2L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NFE2L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NFE2L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NFE2L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NFE2L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 NFE2L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NFE2L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NFE2L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NFE2L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 NFE2L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 NFE2L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 NFE2L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 NFE2L2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001E0AEA NFE2L2 23236440 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00002E92A8 NFE2L2 23236440 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00001B341F NFE2L2 23236440 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00002E92A8 NFE2L2 23236440 25416803 27508019 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001E0AEA NFE2L2 23236440 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00001B341F NFE2L2 22473208 23236440 25226451 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,chromatin immunoprecipitation assay,clip,miRNA interference luciferase reporter assay TarBase
URS000003ABC4 NFE2L2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000600E6 NFE2L2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000285DCB NFE2L2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 NFE2L2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000028BB8 NFE2L2 25416803 27386246 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
GSK3B NFE2L2 22135298 phosphorylation N/A PhosphoSite
CDK5 NFE2L2 22135298 phosphorylation N/A PhosphoSite
FYN NFE2L2 22135298 phosphorylation N/A PhosphoSite
CUL3 NFE2L2 25361965 interaction type N/A PTMCode2
NFE2L2 CUL3 25361965 interaction type N/A PTMCode2
MAFK NFE2L2 25361965 interaction type N/A PTMCode2
NFE2L2 MAFK 25361965 interaction type N/A PTMCode2
JUN NFE2L2 25361965 interaction type N/A PTMCode2
NFE2L2 JUN 25361965 interaction type N/A PTMCode2
MAFG NFE2L2 25361965 interaction type N/A PTMCode2
NFE2L2 MAFG 25361965 interaction type N/A PTMCode2
KEAP1 NFE2L2 25361965 interaction type N/A PTMCode2
NFE2L2 KEAP1 25361965 interaction type N/A PTMCode2
ATF4 NFE2L2 25361965 interaction type N/A PTMCode2
NFE2L2 ATF4 25361965 interaction type N/A PTMCode2
NRF1 NFE2L2 25361965 interaction type N/A PTMCode2
NFE2L2 NRF1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MAPK9 NFE2L2 25348397 N/A physical interaction ComPPI
KPNA3 NFE2L2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RARA NFE2L2 18048326 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDKN1A NFE2L2 25348397 N/A physical interaction ComPPI
ATF4 NFE2L2 11274184 14525934 24234451 25348397 26700459 27898060 association,physical association two hybrid,experimental interaction detection,physical interaction,chromatin immunoprecipitation assay,in vitro,in vivo,proximity ligation assay,two hybrid ComPPI,HPRD,IntAct,OmniPath
KEAP1 NFE2L2 11439354 14525934 16888629 17015834 18757741 19706542 21988832 24234451 25348397 9887101 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,isothermal titration calorimetry,pull down,x-ray crystallography,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
UBE2E2 NFE2L2 25348397 N/A physical interaction ComPPI
UBE2E3 NFE2L2 25348397 N/A physical interaction ComPPI
PRKCQ NFE2L2 25348397 N/A physical interaction ComPPI
SIAH2 NFE2L2 25348397 N/A physical interaction ComPPI
MAPK8 NFE2L2 25348397 N/A physical interaction ComPPI
PRKCA NFE2L2 25348397 N/A physical interaction ComPPI
PRKCD NFE2L2 12198130 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CASP3 NFE2L2 10510468 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
JUN NFE2L2 12805554 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MAF NFE2L2 25348397 N/A physical interaction ComPPI
CREBBP NFE2L2 11683914 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SUMO1 NFE2L2 25348397 N/A physical interaction ComPPI
TCF20 NFE2L2 25348397 N/A physical interaction ComPPI
HDAC3 NFE2L2 25348397 N/A physical interaction ComPPI
CHD6 NFE2L2 14525934 16314513 25348397 27898060 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD,OmniPath
JUND NFE2L2 14525934 25348397 9872330 N/A experimental interaction detection,in vivo ComPPI,HPRD
NFE2L2 MAFK 10747902 11013233 14525934 21988832 24234451 25348397 9150357 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct
NFE2L2 PPARG 10930400 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
NFE2L2 MAFG 11013233 14525934 18692475 21988832 24234451 25348397 25416956 9150357 physical association two hybrid,experimental interaction detection,physical interaction,mammalian protein protein interaction trap,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct
NFE2L2 EIF2AK3 14517290 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
NFE2L2 MAFF 12490281 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
NFE2L2 PMF1 10419538 11256947 12020345 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
NFE2L2 COPS7A 12020345 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
NFE2L2 CASP1 10510468 14525934 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
NFE2L2 TRIM24 25348397 N/A physical interaction ComPPI
NFE2L2 SMARCA4 25348397 N/A physical interaction ComPPI
NFE2L2 CUL3 25348397 N/A physical interaction ComPPI
NFE2L2 NCOR2 25348397 N/A physical interaction ComPPI
NFE2L2 NCOR1 25348397 N/A physical interaction ComPPI
NFE2L2 YY1 25348397 N/A physical interaction ComPPI
NFE2L2 MYC 25348397 N/A physical interaction ComPPI
NFE2L2 BACH1 25348397 N/A physical interaction ComPPI
NFE2L2 PRKCH 25348397 N/A physical interaction ComPPI
NFE2L2 PRKCG 25348397 N/A physical interaction ComPPI
NFE2L2 SQSTM1 25348397 N/A physical interaction ComPPI
NFE2L2 GADD45GIP1 25348397 N/A physical interaction ComPPI
NFE2L2 GSK3B 25348397 N/A physical interaction ComPPI
NFE2L2 PGAM5 25348397 N/A physical interaction ComPPI
NFE2L2 ENC1 25348397 N/A physical interaction ComPPI
NFE2L2 BPTF 25348397 N/A physical interaction ComPPI
NFE2L2 SUMO2 25348397 N/A physical interaction ComPPI
NFE2L2 RNF4 25348397 N/A physical interaction ComPPI
NFE2L2 NFE2L3 25348397 N/A physical interaction ComPPI
NFE2L2 CREB3 25348397 N/A physical interaction ComPPI
NFE2L2 AHR 25348397 N/A physical interaction ComPPI
NFE2L2 RBMX 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NFE2L2 NQO1 25348397 N/A physical interaction ComPPI
NFE2L2 BRCA1 25348397 N/A physical interaction ComPPI
NFE2L2 AKT1 25348397 N/A physical interaction ComPPI
NFE2L2 MAP2K1 25348397 N/A physical interaction ComPPI
NFE2L2 MAPK7 25348397 N/A physical interaction ComPPI
NFE2L2 HDAC1 25348397 N/A physical interaction ComPPI
NFE2L2 HDAC2 25348397 N/A physical interaction ComPPI
NFE2L2 FBXW11 25348397 N/A physical interaction ComPPI
NFE2L2 TNNT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NFE2L2 WAC 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NFE2L2 UBC 17420218 17591699 17785452 18512965 19279002 19786557 20173742 20307651 21245377 25348397 27898060 N/A anti tag coimmunoprecipitation,covalent binding,physical interaction,comigration in sds page ComPPI,OmniPath
NFE2L2 BTRC 21245377 22964642 25348397 25900982 26091241 27898060 N/A physical interaction ComPPI,OmniPath
NFE2L2 TRIM28 25348397 N/A physical interaction ComPPI
NFE2L2 RBM45 25348397 N/A physical interaction ComPPI
NFE2L2 CDH1 25348397 N/A physical interaction ComPPI
NFE2L2 PAQR3 25348397 N/A physical interaction ComPPI
NFE2L2 PPP1R13L 25348397 N/A physical interaction ComPPI
NFE2L2 DCAF11 25348397 N/A physical interaction ComPPI
NFE2L2 NCF1B 25348397 N/A physical interaction ComPPI
NFE2L2 NCF1 25348397 N/A physical interaction ComPPI
NFE2L2 UBA52 25348397 N/A anti tag coimmunoprecipitation,covalent binding,physical interaction,comigration in sds page ComPPI
NFE2L2 EEF1G 21597468 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NFE2L2 KDM1A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBB NFE2L2 25348397 N/A anti tag coimmunoprecipitation,covalent binding,physical interaction,comigration in sds page ComPPI
RPS27A NFE2L2 25348397 N/A anti tag coimmunoprecipitation,covalent binding,physical interaction,comigration in sds page ComPPI
MAP2K2 NFE2L2 25348397 N/A physical interaction ComPPI
NFE2 NFE2L2 12805554 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
NFE2L2 HYOU1 24234451 26700459 association chromatin immunoprecipitation assay IntAct
NFE2L2 PML 24234451 28777872 physical association pull down IntAct
H2BC9 NFE2L2 24234451 30021884 physical association cross-linking study IntAct
HNRNPD NFE2L2 24234451 30021884 physical association cross-linking study IntAct
CDK5 NFE2L2 25909891 27898060 N/A N/A OmniPath
SRC NFE2L2 18802114 27898060 N/A N/A OmniPath
PRKCA NFE2L2 12198130 12947090 19920073 27898060 stimulant N/A OmniPath
PRKCB NFE2L2 12198130 27898060 stimulant N/A OmniPath
EIF2AK3 NFE2L2 14517290 27898060 stimulant N/A OmniPath
FYN NFE2L2 16513647 21097520 21690096 27898060 inhibition N/A OmniPath
PRKCD NFE2L2 12198130 19920073 27898060 N/A N/A OmniPath
NFE2L2 ABCC3 19345732 27898060 N/A N/A OmniPath
NFE2L2 NQO1 18241676 18535259 27898060 stimulant N/A OmniPath
NFE2L2 PRDX1 15289456 27898060 stimulant N/A OmniPath
NFE2L2 CXCL8 16220540 27898060 N/A N/A OmniPath
HDAC2 NFE2L2 18241676 27898060 inhibition N/A OmniPath
JUND NFE2L2 16545679 27898060 9872330 N/A N/A OmniPath
SIRT1 NFE2L2 20623181 27898060 inhibition N/A OmniPath
HDAC3 NFE2L2 18241676 27898060 inhibition N/A OmniPath
ESR1 NFE2L2 20623181 27898060 inhibition N/A OmniPath
MAPK13 NFE2L2 16951197 27898060 inhibition N/A OmniPath
AKT1 NFE2L2 19931411 27898060 N/A N/A OmniPath
PTGS2 NFE2L2 15917255 27898060 N/A N/A OmniPath
VEGFA NFE2L2 20185790 22033923 27898060 N/A N/A OmniPath
NFE2L2 VEGFA 20185790 22033923 27898060 N/A N/A OmniPath
MAF NFE2L2 18694732 27898060 stimulant N/A OmniPath
MAFG NFE2L2 11013233 16189514 18585411 18692475 21988832 22942279 23661758 23737527 24140708 25416956 27898060 9150357 N/A N/A OmniPath
JUNB NFE2L2 27898060 9872330 N/A N/A OmniPath
MAPK3 NFE2L2 19931411 27898060 N/A N/A OmniPath
TRIM28 NFE2L2 21382013 25995248 27898060 N/A N/A OmniPath
NFE2L2 OSGIN1 18535259 27898060 stimulant N/A OmniPath
CREBBP NFE2L2 11154691 11683914 18241676 19273602 21196497 27898060 stimulant N/A OmniPath
MAPK14 NFE2L2 16951197 27898060 inhibition N/A OmniPath
NFE2L2 NFKBIA 16246346 27898060 N/A N/A OmniPath
NFE2L2 HMOX1 18241676 18535259 27898060 stimulant N/A OmniPath
BACH1 NFE2L2 15734732 19897490 27898060 inhibition N/A OmniPath
SMARCA4 NFE2L2 16923960 27898060 N/A N/A OmniPath
HDAC1 NFE2L2 18241676 27898060 inhibition N/A OmniPath
TNF NFE2L2 18202225 27898060 stimulant N/A OmniPath
KLF2 NFE2L2 18467642 27898060 stimulant N/A OmniPath
MAP2K6 NFE2L2 16951197 27898060 inhibition N/A OmniPath
BRCA1 NFE2L2 15520196 27898060 N/A N/A OmniPath
EP300 NFE2L2 19273602 27898060 N/A N/A OmniPath
MAPK1 NFE2L2 12198130 16308312 27898060 N/A N/A OmniPath
CSNK2A1 NFE2L2 17512459 27898060 inhibition N/A OmniPath
NFE2L2 GCLM 16485034 18535259 19808663 27898060 stimulant N/A OmniPath
KEAP1 NFE2L2 11439354 11909699 12145307 14517290 14585973 15143058 15475350 15572695 15601839 15985429 16006525 16507366 16581765 16785233 16790436 16888629 17020408 17420218 17462537 17591699 17785452 17822677 17903176 18358244 18387606 18417180 18512965 18694732 18757741 18981988 19279002 19560419 19920073 20027226 20173742 20421418 20463144 20484052 20486933 20599909 21262351 21383067 21988832 22215675 22245129 22448038 22558124 22688683 23066931 23382044 23645672 23722832 23857982 23986495 24011591 24130096 24322982 24366543 24512214 24704364 24997453 25582950 25628777 26536456 27898060 9887101 inhibition N/A OmniPath
NFE2L2 YY1 20309604 27898060 N/A N/A OmniPath
NFE2L2 SQSTM1 20452972 27898060 N/A N/A OmniPath
MAPK11 NFE2L2 16951197 27898060 inhibition N/A OmniPath
GSK3B NFE2L2 16551619 22751928 27898060 inhibition N/A OmniPath
RBX1 NFE2L2 15572695 27898060 inhibition N/A OmniPath
MAPK8 NFE2L2 16308312 27898060 N/A N/A OmniPath
NFE2L2 CCL2 16246346 27898060 inhibition N/A OmniPath
BTG2 NFE2L2 22493435 27898060 stimulant N/A OmniPath
IKBKB NFE2L2 18241676 27898060 inhibition N/A OmniPath
JUN NFE2L2 12805554 19666106 20232342 27898060 9872330 N/A N/A OmniPath
CUL3 NFE2L2 15367669 15601839 17015834 27898060 N/A N/A OmniPath
NFKBIE NFE2L2 18241676 27898060 inhibition N/A OmniPath
MAPK12 NFE2L2 16951197 27898060 inhibition N/A OmniPath
PTMA NFE2L2 15657435 27898060 N/A N/A OmniPath
NFE2L2 CFTR 20309604 27898060 inhibition N/A OmniPath
PAG1 NFE2L2 11683914 27898060 N/A N/A OmniPath
NFE2L2 ABCC2 18038766 27898060 N/A N/A OmniPath
PIK3CG NFE2L2 19272177 27898060 N/A N/A OmniPath
GADD45GIP1 NFE2L2 20427290 27898060 inhibition N/A OmniPath
NFE2L2 VAMP1 16246346 27898060 inhibition N/A OmniPath
NFE2L2 UGT2B7 18622263 27898060 N/A N/A OmniPath
MAFF NFE2L2 12490281 23661758 23737527 26186194 27898060 N/A N/A OmniPath
MT3 NFE2L2 18554677 27898060 stimulant N/A OmniPath
NFE2L2 MUC5AC 20216230 27898060 inhibition N/A OmniPath
ENC1 NFE2L2 17875699 18981988 19424503 20511222 27898060 inhibition N/A OmniPath
NOX1 NFE2L2 18802114 20347035 27898060 N/A N/A OmniPath
PGAM5 NFE2L2 18387606 27898060 inhibition,stimulant N/A OmniPath
EPX NFE2L2 20229611 27898060 N/A N/A OmniPath
NFE2L2 CBR3 20806931 27898060 N/A N/A OmniPath

Visualization










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