Gene Information gene info

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GENE：SAT2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SAT2
FullNmae spermidine/spermine N1-acetyltransferase family member 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23160
EnsembleID ENSG00000141504
Uniprot Q96F10

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SAT2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SAT2 ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SAT2 GO:0004145,GO:0005515,GO:0005737,GO:0008080,GO:0008080,GO:0032918,GO:0032919,GO:0032920,GO:0042802,GO:0046204,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SAT2 hsa:112483 path:hsa00330 Arginine and proline metabolism - Homo sapiens (human)
SAT2 hsa:112483 path:hsa01100 Metabolic pathways - Homo sapiens (human)
SAT2 hsa:112483 path:hsa04216 Ferroptosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F1 SAT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000021D7C8 SAT2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
VHL SAT2 25361965 interaction type N/A PTMCode2
SAT2 VHL 25361965 interaction type N/A PTMCode2
SAT2 HIF1A 25361965 interaction type N/A PTMCode2
HIF1A SAT2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SAT1 SAT2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
SAT2 HIF1A 25348397 N/A physical interaction ComPPI
SAT2 ELOC 25348397 N/A physical interaction ComPPI
SAT2 VHL 25348397 N/A physical interaction ComPPI
SAT2 KAT2B 25348397 N/A physical interaction ComPPI
SAT2 PANK2 25348397 N/A physical interaction ComPPI
SAT2 TGFBR1 14525934 15761153 N/A experimental interaction detection HPRD
SAT2 SAT2 16230384 24234451 25416956 30476227 physical association affinity chromatography technology,two hybrid array,two hybrid prey pooling approach IntAct,TheBiogrid
NDUFA10 SAT2 24234451 30021884 physical association cross-linking study IntAct
C1QBP SAT2 24234451 30021884 physical association cross-linking study IntAct
SMC1A SAT2 24234451 30021884 physical association cross-linking study IntAct
ERI2 SAT2 11238380 12453419 14559996 16230384 16452305 16940996 20460684 22939629 26344197 30476227 8895581 colocalization,association,physical association affinity chromatography technology,biochemical TheBiogrid
IL17F SAT2 17643375 30476227 physical association affinity chromatography technology TheBiogrid
OR2D3 SAT2 20130577 30476227 physical association affinity chromatography technology TheBiogrid
SAT2 DTD2 22939629 26344197 30476227 colocalization biochemical TheBiogrid
GPR146 SAT2 23752268 30476227 physical association affinity chromatography technology TheBiogrid
TLCD1 SAT2 26344197 30476227 colocalization biochemical TheBiogrid

Source Target Pmid Interactiontype Methods Database
URS00008BED1B SAT2 27087310 direct interaction,inhibition N/A NPInter

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