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GENE：HSBP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HSBP1
FullNmae heat shock factor binding protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5203
EnsembleID ENSG00000230989
Uniprot O75506

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HSBP1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HSBP1 ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
HSBP1 GO:0000122,GO:0003714,GO:0005515,GO:0005634,GO:0005654,GO:0005829,GO:0019896,GO:0035987,GO:0042802,GO:0070370,GO:1904115

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 HSBP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 HSBP1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 HSBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HSBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HSBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HSBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HSBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HSBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000040FA88 HSBP1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000553F51 HSBP1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA HSBP1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 HSBP1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 HSBP1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 HSBP1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 HSBP1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E HSBP1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 HSBP1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002F5FEE HSBP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00006AA21F HSBP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000331800 HSBP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0920 HSBP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002A71AD HSBP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 HSBP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 HSBP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F HSBP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C HSBP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 HSBP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB HSBP1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000101787 HSBP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5FFC HSBP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000C48FA HSBP1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00006DE17B HSBP1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000486E0B HSBP1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000021202F HSBP1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00005CCD18 HSBP1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075CC78 HSBP1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075D814 HSBP1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001012BC HSBP1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00004E008F HSBP1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00003AD2AA HSBP1 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HSPA1A HSBP1 25361965 interaction type N/A PTMCode2
HSBP1 HSPA1A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
WASHC3 HSBP1 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
HSBP1 KRTAP10-7 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HSBP1 HSPA1A 14525934 25348397 9649501 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
HSBP1 HSPA1B 25348397 N/A in vitro,in vivo ComPPI
HSBP1 HSF1 14525934 25348397 9649501 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
HSBP1 HSPA4 25348397 N/A physical interaction ComPPI
HSBP1 RB1CC1 20562859 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSBP1 RRBP1 25348397 N/A physical interaction ComPPI
HSBP1 VCP 25348397 N/A physical interaction ComPPI
HSBP1 KIFC3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HSBP1 SDCBP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HSBP1 CCHCR1 25348397 N/A physical interaction ComPPI
HSBP1 KIAA1217 25348397 N/A physical interaction ComPPI
HSBP1 LNX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HSBP1 KRTAP10-3 25348397 N/A physical interaction ComPPI
HSBP1 NOTCH2NLA 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HSBP1 IFT57 25348397 N/A physical interaction ComPPI
HSBP1 BORCS6 25348397 N/A physical interaction ComPPI
HSBP1 SCLT1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSBP1 ODF2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HSBP1 BSPRY 25348397 N/A physical interaction ComPPI
HSBP1 POC1B 25348397 N/A physical interaction ComPPI
HSBP1 RCAN2 25348397 N/A physical interaction ComPPI
HSBP1 LIN54 17531812 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
HSBP1 SDCBP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSBP1 BRK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSBP1 ZBTB25 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSBP1 GORASP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSBP1 CYSRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSBP1 KRTAP10-9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSBP1 KRTAP1-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSBP1 DDIT4L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSBP1 MPP7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX11 HSBP1 25348397 N/A physical interaction ComPPI
HSBP1 HSBP1 11679589 14525934 24234451 25416956 physical association experimental interaction detection,two hybrid array,two hybrid prey pooling approach,two hybrid HPRD,IntAct
HSBP1 HSF1 27898060 9649501 9869631 inhibition N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00008B89F9 HSBP1 27087310 direct interaction,inhibition N/A NPInter

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