Gene Information gene info

  1. Home

GENE：SQLE

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SQLE
FullNmae squalene epoxidase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11279
EnsembleID ENSG00000104549
Uniprot Q14534

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SQLE ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SQLE ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
SQLE GO:0004506,GO:0004506,GO:0004506,GO:0005515,GO:0005783,GO:0005789,GO:0008203,GO:0010033,GO:0016020,GO:0016126,GO:0016126,GO:0016126,GO:0042127,GO:0043231,GO:0071949,GO:0140042

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SQLE hsa:6713 path:hsa00100 Steroid biosynthesis - Homo sapiens (human)
SQLE hsa:6713 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SQLE IRF4 18568025 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 SQLE 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SQLE 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SQLE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SQLE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SQLE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SQLE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SQLE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SQLE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A SQLE 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SQLE 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 SQLE 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000000B1C9 SQLE 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000016914 SQLE 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CHRND SQLE 25348397 N/A physical interaction ComPPI
ATP2B2 SQLE 25348397 N/A physical interaction ComPPI
CREB3 SQLE 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ALDOC SQLE 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FAF2 SQLE 25348397 N/A physical interaction ComPPI
HLA-DRB1 SQLE 25348397 N/A physical interaction ComPPI
CREB3L1 SQLE 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TMCO3 SQLE 25348397 N/A physical interaction ComPPI
ZNRF4 SQLE 25348397 N/A physical interaction ComPPI
MARCHF6 SQLE 24234451 24449766 24840124 25348397 27898060 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
SQLE ZNF641 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SQLE TREML2 25348397 N/A physical interaction ComPPI
SQLE SLC39A12 25348397 N/A physical interaction ComPPI
SQLE SLC18A1 25348397 N/A physical interaction ComPPI
SQLE PCDHGA5 25348397 N/A physical interaction ComPPI
SQLE SLC17A2 25348397 N/A physical interaction ComPPI
SQLE REEP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

Source Target Pmid Interactiontype Methods Database
URS00009AD1EA SQLE 27087310 direct interaction,inhibition N/A NPInter

Visualization










  Return