Gene Information gene info

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GENE：ING4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ING4
FullNmae inhibitor of growth family member 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19423
EnsembleID ENSG00000111653
Uniprot Q9UNL4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ING4 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ING4 GO:0000123,GO:0001558,GO:0001558,GO:0003713,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006338,GO:0006355,GO:0006355,GO:0006355,GO:0006473,GO:0006915,GO:0007049,GO:0008285,GO:0035064,GO:0035064,GO:0036408,GO:0043065,GO:0043995,GO:0043996,GO:0043997,GO:0045111,GO:0045892,GO:0045893,GO:0045926,GO:0046872,GO:0051726,GO:0140889,GO:1902164,GO:1902749,GO:2000278

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ING4 CREB1 15753290 23180781 physical association anti tag coimmunoprecipitation InnateDB
ING4 CEBPD 21072181 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 ING4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ING4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ING4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ING4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 ING4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ING4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ING4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX3 ING4 17956589 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000160683 ING4 21106054 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 ING4 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000002103A ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000236310 ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000D6C3F ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000029D793 ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000014F13C ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000383DF4 ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000519450 ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002394F5 ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000C5969 ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000BF7F9 ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005485E8 ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001919B0 ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000036B845 ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005DEC41 ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000235862 ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003AD2AA ING4 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PPFIA1 ING4 25361965 interaction type N/A PTMCode2
ING4 PPFIA1 25361965 interaction type N/A PTMCode2
ING4 RELA 25361965 interaction type N/A PTMCode2
RELA ING4 25361965 interaction type N/A PTMCode2
TP53 ING4 25361965 interaction type N/A PTMCode2
ING4 TP53 25361965 interaction type N/A PTMCode2
EGLN1 ING4 25361965 interaction type N/A PTMCode2
ING4 EGLN1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HOXB9 ING4 25348397 N/A physical interaction ComPPI
JADE3 ING4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPFIA1 ING4 16973615 17363573 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
DPPA4 ING4 25348397 N/A physical interaction ComPPI
PADI4 ING4 25348397 N/A physical interaction ComPPI
NAV2 ING4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EP300 ING4 25348397 N/A physical interaction,in vivo ComPPI
UBE2D2 ING4 25348397 N/A physical interaction ComPPI
CDKN2A ING4 25348397 N/A physical interaction ComPPI
MYC ING4 25348397 N/A physical interaction ComPPI
RELA ING4 15029197 18779315 23624912 25348397 27898060 N/A two hybrid,physical interaction,in vivo ComPPI,OmniPath
MAPK8IP2 ING4 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SUV39H1 ING4 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
H3-4 ING4 25348397 N/A physical interaction ComPPI
EGFR ING4 25348397 N/A physical interaction ComPPI
CDC34 ING4 25348397 N/A physical interaction ComPPI
H2AC14 ING4 24234451 25348397 26496610 association anti tag coimmunoprecipitation ComPPI,IntAct
H3C15 ING4 25348397 N/A physical interaction ComPPI
POGZ ING4 25348397 N/A physical interaction ComPPI
NOLC1 ING4 25348397 N/A physical interaction ComPPI
BRD1 ING4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ING4 EGLN1 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
ING4 KAT7 16387653 17954561 22334692 24234451 25348397 26496610 27898060 association anti tag coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct,OmniPath
ING4 TP53 12750254 15251430 15882981 17954561 18775696 20053357 21177815 21454715 23967213 24234451 25348397 27898060 physical association coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
ING4 CDKN2A 25348397 N/A physical interaction ComPPI
ING4 JADE1 25348397 N/A physical interaction ComPPI
ING4 JADE2 25348397 N/A physical interaction ComPPI
ING4 MEAF6 25348397 N/A physical interaction ComPPI
ING4 G3BP2 16973615 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ING4 TLX3 25348397 N/A physical interaction ComPPI
ING4 MSX1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ING4 GADD45A 23388825 25348397 27898060 N/A physical interaction ComPPI,OmniPath
ING4 HNRNPD 23603392 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct,OmniPath
ING4 KMT2A 25348397 N/A physical interaction ComPPI
ING4 BRPF1 25348397 N/A physical interaction ComPPI
ING4 H2BC15 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ING4 RPP38 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ING4 H2AJ 25348397 N/A physical interaction ComPPI
ING4 TRIM56 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ING4 PCGF1 25348397 N/A physical interaction ComPPI
ING4 BCOR 25348397 N/A physical interaction ComPPI
ING4 BECN1 22081109 24234451 25348397 physical association two hybrid ComPPI,IntAct
ING4 GRIPAP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ING4 BEX3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
H3C1 ING4 17157298 20053357 20705953 24234451 25348397 27898060 N/A nuclear magnetic resonance,physical interaction ComPPI,IntAct,OmniPath
H3-3A ING4 20953165 24234451 25348397 physical association pull down ComPPI,IntAct
EBNA1BP2 ING4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDIA3 ING4 24234451 30021884 physical association cross-linking study IntAct

Visualization










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