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GENE：PDLIM1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PDLIM1
FullNmae PDZ and LIM domain 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2067
EnsembleID ENSG00000107438
Uniprot O00151

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PDLIM1 disulfidptosis 39146597 Previous studies have identified 15 essential genes (FLNA, FLNB, MYH9, TLN1, ACTB, MYL6, MYH10, CAPZB, DSTN, IQGAP1, ACTN4, PDLIM1, CD2AP, INF2, SLC7A11) associated with disulfidptosis. retulator signature

Go Annotation:

GeneSymbol Go id
PDLIM1 GO:0001666,GO:0001725,GO:0001725,GO:0003713,GO:0003779,GO:0003779,GO:0005515,GO:0005667,GO:0005737,GO:0005856,GO:0005912,GO:0005912,GO:0005925,GO:0006357,GO:0006979,GO:0007507,GO:0010761,GO:0030011,GO:0030018,GO:0030018,GO:0030036,GO:0030036,GO:0030950,GO:0031941,GO:0043149,GO:0045893,GO:0046872,GO:0051371,GO:0061061,GO:0098609,GO:0098641

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL7R PDLIM1 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR PDLIM1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 PDLIM1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 PDLIM1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PDLIM1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PDLIM1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 PDLIM1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 PDLIM1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PDLIM1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PDLIM1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PDLIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PDLIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PDLIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PDLIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PDLIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PDLIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PDLIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PDLIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PDLIM1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 PDLIM1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00005CC20C PDLIM1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD PDLIM1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
RLIM PDLIM1 25361965 interaction type N/A PTMCode2
PDLIM1 RLIM 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ACTN3 PDLIM1 25348397 N/A physical interaction ComPPI
EIF1B PDLIM1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
VIM PDLIM1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HK2 PDLIM1 25348397 N/A physical interaction ComPPI
CLNS1A PDLIM1 25348397 N/A physical interaction ComPPI
NUDT12 PDLIM1 25348397 N/A physical interaction ComPPI
SCYL2 PDLIM1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ACTN4 PDLIM1 10753915 14525934 16189514 24234451 25348397 physical association experimental interaction detection,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,in vivo ComPPI,HPRD,IntAct
ACTN1 PDLIM1 10753915 11110697 11973348 14525934 25348397 26186194 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
CANX PDLIM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CDH1 PDLIM1 25348397 N/A physical interaction ComPPI
GORASP2 PDLIM1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MAPK6 PDLIM1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ACTN2 PDLIM1 10861853 14525934 25348397 26186194 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
EEA1 PDLIM1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RLIM PDLIM1 11882901 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SOX2 PDLIM1 25348397 N/A physical interaction ComPPI
RPS6KA5 PDLIM1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDLIM1 PITX2 12464179 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PDLIM1 STK35 11973348 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
PDLIM1 GFAP 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PDLIM1 AGK 14525934 16169070 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
PDLIM1 PGS1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PDLIM1 ESR1 25348397 N/A physical interaction ComPPI
PDLIM1 SUPT4H1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PDLIM1 IGBP1 25348397 N/A physical interaction ComPPI
PDLIM1 PNPT1 25348397 N/A physical interaction ComPPI
PDLIM1 NUBP1 25348397 N/A physical interaction ComPPI
PDLIM1 NXF1 25348397 N/A physical interaction ComPPI
PDLIM1 CUL7 25348397 N/A physical interaction ComPPI
PDLIM1 LUZP4 25348397 N/A physical interaction ComPPI
PDLIM1 RANGRF 25348397 N/A physical interaction ComPPI
PDLIM1 HSPB1 25348397 N/A physical interaction ComPPI
PDLIM1 STMN1 25348397 N/A physical interaction ComPPI
PDLIM1 LIMA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDLIM1 FBXO31 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDLIM1 G3BP1 25348397 N/A physical interaction ComPPI
PDLIM1 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
PDLIM1 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
PDLIM1 EZR 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ARIH2 PDLIM1 25348397 N/A physical interaction ComPPI
PTGER4 PDLIM1 24234451 28298427 physical association ubiquitin reconstruction IntAct
HNRNPD PDLIM1 24234451 30021884 physical association cross-linking study IntAct
IL7R PDLIM1 20167604 27898060 N/A N/A OmniPath

Visualization










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